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Select item 61983721.

Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma

Yu Zheng, Baihui Li, Jian Wang, Yanjuan Xiong, Kaiyuan Wang, Ying Qi, Houfang Sun, Lei Wu, Lili Yang

Clin Epigenetics. 2018; 10: 129. Published online 2018 Oct 22. doi: 10.1186/s13148-018-0562-4

PMCID:: PMC6198372

Abstract Article PDF–3.1M

Select item 50084052.

Automethylation of SUV39H2, an oncogenic histone lysine methyltransferase, regulates its binding affinity to substrate proteins

Lianhua Piao, Makoto Nakakido, Takehiro Suzuki, Naoshi Dohmae, Yusuke Nakamura, Ryuji Hamamoto

Oncotarget. 2016 Apr 19; 7(16): 22846–22856. Published online 2016 Mar 14. doi: 10.18632/oncotarget.8072

PMCID:: PMC5008405

Abstract Article PDF–4.4M

Select item 74715093.

Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model

Jennings Luu, Les Kallestad, Thanh Hoang, Dominik Lewandowski, Zhiqian Dong, Seth Blackshaw, Krzysztof Palczewski

Hum Mol Genet. 2020 Aug 29; 29(15): 2611–2624. Published online 2020 Jul 21. doi: 10.1093/hmg/ddaa158

PMCID:: PMC7471509

Abstract Article PDF–2.5M

Select item 53705144.

Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C

Xi-yu Liu, Hong Li

J Diabetes Res. 2017; 2017: 8365762. Published online 2017 Mar 15. doi: 10.1155/2017/8365762

PMCID:: PMC5370514

Abstract Article PDF–1011K

Select item 46272835.

SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells

Lianhua Piao, Takehiro Suzuki, Naoshi Dohmae, Yusuke Nakamura, Ryuji Hamamoto

Oncotarget. 2015 Jul 10; 6(19): 16939–16950. Published online 2015 Jul 3. doi: 10.18632/oncotarget.4760

PMCID:: PMC4627283

Abstract Article PDF–1.1M

Select item 53031416.

Androgen Receptor Regulation by Histone Methyltransferase Suppressor of variegation 3–9 homolog 2 and Melanoma antigen-A11

Emily B. Askew, Suxia Bai, Amanda B. Parris, John T. Minges, Elizabeth M. Wilson

Mol Cell Endocrinol. Author manuscript; available in PMC 2018 Mar 5.

Published in final edited form as: Mol Cell Endocrinol. 2017 Mar 5; 443: 42–51. Published online 2016 Dec 29. doi: 10.1016/j.mce.2016.12.028

PMCID:: PMC5303141

Abstract Article PDF–3.0M

Select item 31980957.

Genetic Examination of SETD7 and SUV39H1/H2 Methyltransferases and the Risk of Diabetes Complications in Patients With Type 1 Diabetes

Anna Syreeni, Assam El-Osta, Carol Forsblom, Niina Sandholm, Maikki Parkkonen, Lise Tarnow, Hans-Henrik Parving, Amy J. McKnight, Alexander P. Maxwell, Mark E. Cooper, Per-Henrik Groop, on behalf of the FinnDiane Study Group

Diabetes. 2011 Nov; 60(11): 3073–3080. Published online 2011 Oct 17. doi: 10.2337/db11-0073

PMCID:: PMC3198095

Abstract Article PDF–605K

Select item 29664068.

Polycomb CBX7 Directly Controls Trimethylation of Histone H3 at Lysine 9 at the p16 Locus

Qiang Li, Xiuhong Wang, Zheming Lu, Baozhen Zhang, Zhenpo Guan, Zhaojun Liu, Qiming Zhong, Liankun Gu, Jing Zhou, Budong Zhu, Jiafu Ji, Dajun Deng

PLoS One. 2010; 5(10): e13732. Published online 2010 Oct 29. doi: 10.1371/journal.pone.0013732

PMCID:: PMC2966406

Abstract Article PDF–2.9M

Select item 12718079.

A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells

Slimane Ait-Si-Ali, Valentina Guasconi, Lauriane Fritsch, Hakima Yahi, Redha Sekhri, Irina Naguibneva, Philippe Robin, Florence Cabon, Anna Polesskaya, Annick Harel-Bellan

EMBO J. 2004 Feb 11; 23(3): 605–615. Published online 2004 Feb 5. doi: 10.1038/sj.emboj.7600074

PMCID:: PMC1271807

Abstract Article PDF–260K

Select item 279760810.

Structural Biology of Human H3K9 Methyltransferases

Hong Wu, Jinrong Min, Vladimir V. Lunin, Tatiana Antoshenko, Ludmila Dombrovski, Hong Zeng, Abdellah Allali-Hassani, Valérie Campagna-Slater, Masoud Vedadi, Cheryl H. Arrowsmith, Alexander N. Plotnikov, Matthieu Schapira

PLoS One. 2010; 5(1): e8570. Published online 2010 Jan 11. doi: 10.1371/journal.pone.0008570

PMCID:: PMC2797608

Abstract Article PDF–843K

Select item 10219811.

Isolation and Characterization of Suv39h2, a Second Histone H3 Methyltransferase Gene That Displays Testis-Specific Expression

Dónal O'Carroll, Harry Scherthan, Antoine H. F. M. Peters, Susanne Opravil, Andrew R. Haynes, Götz Laible, Stephen Rea, Manfred Schmid, Angelika Lebersorger, Martin Jerratsch, Lydia Sattler, Marie G. Mattei, Paul Denny, Stephen D. M. Brown, Dieter Schweizer, Thomas Jenuwein

Mol Cell Biol. 2000 Dec; 20(24): 9423–9433. doi: 10.1128/mcb.20.24.9423-9433.2000

PMCID:: PMC102198

Abstract Article PDF–2.9M

Select item 613844012.

DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development

Yin‐Li Zhang, Long‐Wen Zhao, Jue Zhang, Rongrong Le, Shu‐Yan Ji, Chuan Chen, Yawei Gao, Dali Li, Shaorong Gao, Heng‐Yu Fan

EMBO J. 2018 Sep 14; 37(18): e98981. Published online 2018 Aug 14. doi: 10.15252/embj.201898981

PMCID:: PMC6138440

Abstract Article PDF–3.2M

Select item 313336613.

Epigenetic Regulation of Surfactant Protein A Gene (SP-A) Expression in Fetal Lung Reveals a Critical Role for Suv39h Methyltransferases during Development and Hypoxia

Houda Benlhabib, Carole R. Mendelson

Mol Cell Biol. 2011 May; 31(10): 1949–1958. doi: 10.1128/MCB.01063-10

PMCID:: PMC3133366

Abstract Article PDF–1.0M

Select item 886983214.

Characterization of the pVHL Interactome in Human Testis Using High-Throughput Library Screening

Antonella Falconieri, Giovanni Minervini, Federica Quaglia, Geppo Sartori, Silvio C. E. Tosatto

Cancers (Basel) 2022 Feb; 14(4): 1009. Published online 2022 Feb 17. doi: 10.3390/cancers14041009

PMCID:: PMC8869832

Abstract Article PDF–1.1M

Select item 220079815.

Genome-Wide Survey and Developmental Expression Mapping of Zebrafish SET Domain-Containing Genes

Xiao-Jian Sun, Peng-Fei Xu, Ting Zhou, Ming Hu, Chun-Tang Fu, Yong Zhang, Yi Jin, Yi Chen, Sai-Juan Chen, Qiu-Hua Huang, Ting Xi Liu, Zhu Chen

PLoS One. 2008; 3(1): e1499. Published online 2008 Jan 30. doi: 10.1371/journal.pone.0001499

PMCID:: PMC2200798

Abstract Article PDF–755K

Select item 404112316.

Genome-wide meta-analysis identifies new susceptibility loci for migraine

Verneri Anttila, Bendik S. Winsvold, Padhraig Gormley, Tobias Kurth, Francesco Bettella, George McMahon, Mikko Kallela, Rainer Malik, Boukje de Vries, Gisela Terwindt, Sarah E. Medland, Unda Todt, Wendy L. McArdle, Lydia Quaye, Markku Koiranen, M. Arfan Ikram, Terho Lehtimäki, Anine H. Stam, Lannie Ligthart, Juho Wedenoja, Ian Dunham, Benjamin M. Neale, Priit Palta, Eija Hamalainen, Markus Schürks, Lynda M Rose, Julie E. Buring, Paul M. Ridker, Stacy Steinberg, Hreinn Stefansson, Finnbogi Jakobsson, Debbie A. Lawlor, David M. Evans, Susan M. Ring, Markus Färkkilä, Ville Artto, Mari A Kaunisto, Tobias Freilinger, Jean Schoenen, Rune R. Frants, Nadine Pelzer, Claudia M. Weller, Ronald Zielman, Andrew C. Heath, Pamela A.F. Madden, Grant W. Montgomery, Nicholas G. Martin, Guntram Borck, Hartmut Göbel, Axel Heinze, Katja Heinze-Kuhn, Frances M.K. Williams, Anna-Liisa Hartikainen, Anneli Pouta, Joyce van den Ende, Andre G. Uitterlinden, Albert Hofman, Najaf Amin, Jouke-Jan Hottenga, Jacqueline M. Vink, Kauko Heikkilä, Michael Alexander, Bertram Muller-Myhsok, Stefan Schreiber, Thomas Meitinger, Heinz Erich Wichmann, Arpo Aromaa, Johan G. Eriksson, Bryan Traynor, Daniah Trabzuni, North American Brain Expression Consortium, UK Brain Expression Consortium, Elizabeth Rossin, Kasper Lage, Suzanne B.R. Jacobs, J. Raphael Gibbs, Ewan Birney, Jaakko Kaprio, Brenda W. Penninx, Dorret I. Boomsma, Cornelia van Duijn, Olli Raitakari, Marjo-Riitta Jarvelin, John-Anker Zwart, Lynn Cherkas, David P. Strachan, Christian Kubisch, Michel D. Ferrari, Arn M.J.M. van den Maagdenberg, Martin Dichgans, Maija Wessman, George Davey Smith, Kari Stefansson, Mark J. Daly, Dale R. Nyholt, Daniel Chasman, Aarno Palotie

Nat Genet. Author manuscript; available in PMC 2014 Jun 2.

Published in final edited form as: Nat Genet. 2013 Aug; 45(8): 912–917. Published online 2013 Jun 23. doi: 10.1038/ng.2676

PMCID:: PMC4041123

Article PDF–571K

Select item 276866717.

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

Ji Luo, Michael J. Emanuele, Danan Li, Chad J. Creighton, Michael R. Schlabach, Thomas F. Westbrook, Kwok-kin Wong, Stephen J. Elledge

Cell. Author manuscript; available in PMC 2009 Nov 29.

Published in final edited form as: Cell. 2009 May 29; 137(5): 835–848. doi: 10.1016/j.cell.2009.05.006

PMCID:: PMC2768667

Abstract Article PDF–4.0M

Select item 954034518.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 674264619.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

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