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Select item 85920891.

AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery

Jeremy D. Baker, Rikki L. Uhrich, Timothy J. Strovas, Aleen D. Saxton, Brian C. Kraemer

SLAS Discov. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: SLAS Discov. 2021 Mar; 26(3): 400–409. Published online 2020 Sep 28. doi: 10.1177/2472555220958387

PMCID:: PMC8592089

Abstract Article PDF–1.4M

Select item 50771842.

The Polyadenosine RNA-binding Protein, Zinc Finger Cys₃His Protein 14 (ZC3H14), Regulates the Pre-mRNA Processing of a Key ATP Synthase Subunit mRNA

Callie P. Wigington, Kevin J. Morris, Laura E. Newman, Anita H. Corbett

J Biol Chem. 2016 Oct 21; 291(43): 22442–22459. Published online 2016 Aug 25. doi: 10.1074/jbc.M116.754069

PMCID:: PMC5077184

Abstract Article PDF–1.2M

Select item 39885693.

A conserved role for the zinc finger polyadenosine RNA binding protein, ZC3H14, in control of poly(A) tail length

Seth M. Kelly, Sara W. Leung, ChangHui Pak, Ayan Banerjee, Kenneth H. Moberg, Anita H. Corbett

RNA. 2014 May; 20(5): 681–688. doi: 10.1261/rna.043984.113

PMCID:: PMC3988569

Abstract Article PDF–289K

Select item 31037134.

The role of MSUT-2 in tau neurotoxicity: a target for neuroprotection in tauopathy?

Jeanna M. Wheeler, Chris R. Guthrie, Brian C. Kraemer

Biochem Soc Trans. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Biochem Soc Trans. 2010 Aug; 38(4): 973–976. doi: 10.1042/BST0380973

PMCID:: PMC3103713

Abstract Article PDF–111K

Select item 30806095.

MSUT2 is a determinant of susceptibility to tau neurotoxicity

Chris R. Guthrie, Lynne Greenup, James B. Leverenz, Brian C. Kraemer

Hum Mol Genet. 2011 May 15; 20(10): 1989–1999. Published online 2011 Feb 25. doi: 10.1093/hmg/ddr079

PMCID:: PMC3080609

Abstract Article PDF–388K

Select item 19414666.

Recognition of polyadenosine RNA by zinc finger proteins

Seth M. Kelly, Suzette A. Pabit, Chad M. Kitchen, Peng Guo, Kavita A. Marfatia, T. J. Murphy, Anita H. Corbett, Keith M. Berland

Proc Natl Acad Sci U S A. 2007 Jul 24; 104(30): 12306–12311. Published online 2007 Jul 13. doi: 10.1073/pnas.0701244104

PMCID:: PMC1941466

Abstract Article PDF–867K

Select item 26804647.

Splice Variants of the Human ZC3H14 Gene Generate Multiple Isoforms of a Zinc Finger Polyadenosine RNA Binding Protein

Sara W. Leung, Luciano H. Apponi, Omar E. Cornejo, Chad M. Kitchen, Sandro R. Valentini, Grace K. Pavlath, Christine M. Dunham, Anita H. Corbett

Gene. Author manuscript; available in PMC 2010 Jun 15.

Published in final edited form as: Gene. 2009 Jun 15; 439(1-2): 71–78. Published online 2009 Mar 18. doi: 10.1016/j.gene.2009.02.022

PMCID:: PMC2680464

Abstract Article PDF–1.0M

Select item 27222258.

SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans

Chris R. Guthrie, Gerard D. Schellenberg, Brian C. Kraemer

Hum Mol Genet. 2009 May 15; 18(10): 1825–1838. Published online 2009 Mar 9. doi: 10.1093/hmg/ddp099

PMCID:: PMC2722225

Abstract Article PDF–643K

Select item 55778099.

The conserved, disease-associated RNA binding protein dNab2 interacts with the Fragile-X protein ortholog in Drosophila neurons

Rick S. Bienkowski, Ayan Banerjee, J. Christopher Rounds, Jennifer Rha, Omotola F. Omotade, Christina Gross, Kevin J. Morris, Sara W. Leung, ChangHui Pak, Stephanie K. Jones, Michael R. Santoro, Stephen T. Warren, James Q. Zheng, Gary J. Bassell, Anita H. Corbett, Kenneth H. Moberg

Cell Rep. Author manuscript; available in PMC 2017 Aug 31.

Published in final edited form as: Cell Rep. 2017 Aug 8; 20(6): 1372–1384. doi: 10.1016/j.celrep.2017.07.038

PMCID:: PMC5577809

Abstract Article PDF–2.2M

Select item 314574110.

Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans

ChangHui Pak, Masoud Garshasbi, Kimia Kahrizi, Christina Gross, Luciano H. Apponi, John J. Noto, Seth M. Kelly, Sara W. Leung, Andreas Tzschach, Farkhondeh Behjati, Seyedeh Sedigheh Abedini, Marzieh Mohseni, Lars R. Jensen, Hao Hu, Brenda Huang, Sara N. Stahley, Guanglu Liu, Kathryn R. Williams, Sharon Burdick, Yue Feng, Subhabrata Sanyal, Gary J. Bassell, Hans-Hilger Ropers, Hossein Najmabadi, Anita H. Corbett, Kenneth H. Moberg, Andreas W. Kuss

Proc Natl Acad Sci U S A. 2011 Jul 26; 108(30): 12390–12395. Published online 2011 Jul 6. doi: 10.1073/pnas.1107103108

PMCID:: PMC3145741

Abstract Article PDF–946K

Select item 470715811.

SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

Ming Wang, Jing Sang, Yanhua Ren, Kejia Liu, Xinyi Liu, Jian Zhang, Haolu Wang, Jian Wang, Amir Orian, Jie Yang, Jing Yi

Protein Cell. 2016 Jan; 7(1): 63–77. Published online 2015 Oct 28. doi: 10.1007/s13238-015-0216-7

PMCID:: PMC4707158

Abstract Article PDF–1.3M

Select item 1033388412.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 729750813.

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser, Dexter Jin, Ania Wronski, Stephen J. Elledge, Charlotte Kuperwasser

Cell Rep. Author manuscript; available in PMC 2020 Jun 16.

Published in final edited form as: Cell Rep. 2019 Sep 24; 28(13): 3435–3449.e5. doi: 10.1016/j.celrep.2019.08.060

PMCID:: PMC7297508

Abstract Article PDF–2.4M

Select item 915369214.

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4

Ashish Kumar, Yuanzhi Lyu, Yuichi Yanagihashi, Chanikarn Chantarasrivong, Vladimir Majerciak, Michelle Salemi, Kang-Hsin Wang, Tomoki Inagaki, Frank Chuang, Ryan R. Davis, Clifford G. Tepper, Kazushi Nakano, Chie Izumiya, Michiko Shimoda, Ken-ichi Nakajima, Alexander Merleev, Zhi-Ming Zheng, Mel Campbell, Yoshihiro Izumiya

Cell Rep. Author manuscript; available in PMC 2022 May 31.

Published in final edited form as: Cell Rep. 2022 May 10; 39(6): 110788. doi: 10.1016/j.celrep.2022.110788

PMCID:: PMC9153692

Abstract Article PDF–3.0M

Select item 573529715.

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics

Y Li, H Sun, C Zhang, J Liu, H Zhang, F Fan, R A Everley, X Ning, Y Sun, J Hu, J Liu, J Zhang, W Ye, X Qiu, S Dai, B Liu, H Xu, S Fu, S P Gygi, C Zhou

Oncogene. 2017 Dec 14; 36(50): 6839–6849. Published online 2017 Aug 28. doi: 10.1038/onc.2017.289

PMCID:: PMC5735297

Abstract Article PDF–1.3M

Select item 666750016.

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF

Rainer W. J. Kaiser, Michael Ignarski, Eric L. Van Nostrand, Christian K. Frese, Manaswita Jain, Sadrija Cukoski, Heide Heinen, Melanie Schaechter, Lisa Seufert, Konstantin Bunte, Peter Frommolt, Patrick Keller, Mark Helm, Katrin Bohl, Martin Höhne, Bernhard Schermer, Thomas Benzing, Katja Höpker, Christoph Dieterich, Gene W. Yeo, Roman-Ulrich Müller, Francesca Fabretti

Sci Rep. 2019; 9: 11071. Published online 2019 Jul 30. doi: 10.1038/s41598-019-47552-3

PMCID:: PMC6667500

Abstract Article PDF–2.8M

Select item 592237717.

Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer

Aida Barreiro-Alonso, Mónica Lamas-Maceiras, Rosa García-Díaz, Esther Rodríguez-Belmonte, Lu Yu, Mercedes Pardo, Jyoti S. Choudhary, María Esperanza Cerdán

Oncotarget. 2018 Apr 10; 9(27): 19050–19064. Published online 2018 Apr 10. doi: 10.18632/oncotarget.24887

PMCID:: PMC5922377

Abstract Article PDF–1.7M

Select item 951327118.

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1

Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin

J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379

PMCID:: PMC9513271

Abstract Article PDF–2.7M

Select item 539338619.

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation

Marni S. Crow, Ileana M. Cristea

Mol Cell Proteomics. 2017 Apr; 16(4 Suppl 1): S200–S214. Published online 2017 Jan 11. doi: 10.1074/mcp.M116.064741

PMCID:: PMC5393386

Abstract Article PDF–2.6M

Select item 827099920.

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis

Rui Liu, Lin-Wen Zeng, Rong Gong, Fanen Yuan, Hong-Bing Shu, Shu Li

Nat Commun. 2021; 12: 4227. Published online 2021 Jul 9. doi: 10.1038/s41467-021-24321-3

PMCID:: PMC8270999

Abstract Article PDF–3.8M

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