PMC Links for Gene (Select 81530) - PMC

Result Filters

Links from Gene

Items: 19

Select item 25689001.

Allosteric Coupling in Pyruvate Dehydrogenase Kinase 2

Alla Klyuyeva, Alina Tuganova, Kirill M. Popov

Biochemistry. Author manuscript; available in PMC 2008 Oct 16.

Published in final edited form as: Biochemistry. 2008 Aug 12; 47(32): 8358–8366. Published online 2008 Jul 16. doi: 10.1021/bi800631h

PMCID:: PMC2568900

Abstract Article PDF–2.0M

Select item 21364102.

The Carboxy-Terminal Tail of Pyruvate Dehydrogenase Kinase 2 Is Required for the Kinase Activity

Alla Klyuyeva, Alina Tuganova, Kirill M. Popov

Biochemistry. Author manuscript; available in PMC 2007 Dec 13.

Published in final edited form as: Biochemistry. 2005 Oct 18; 44(41): 13573–13582. doi: 10.1021/bi0505868

PMCID:: PMC2136410

Abstract Article PDF–1.4M

Select item 19502593.

Amino acid residues responsible for the recognition of dichloroacetate by pyruvate dehydrogenase kinase 2

Alla Klyuyeva, Alina Tuganova, Kirill M. Popov

FEBS Lett. Author manuscript; available in PMC 2007 Sep 7.

Published in final edited form as: FEBS Lett. 2007 Jun 26; 581(16): 2988–2992. Published online 2007 May 29. doi: 10.1016/j.febslet.2007.05.052

PMCID:: PMC1950259

Abstract Article PDF–449K

Select item 42957934.

Elucidation of the Interaction Loci of the Human Pyruvate Dehydrogenase Complex E2·E3BP Core with Pyruvate Dehydrogenase Kinase 1 and Kinase 2 by H/D Exchange Mass Spectrometry and Nuclear Magnetic Resonance

Junjie Wang, Sowmini Kumaran, Jieyu Zhou, Natalia S. Nemeria, Hu Tao, Lazaros Kakalis, Yun-Hee Park, Barbara Birkaya, Mulchand S. Patel, Frank Jordan

Biochemistry. 2015 Jan 13; 54(1): 69–82. Published online 2014 Dec 1. doi: 10.1021/bi5013113

PMCID:: PMC4295793

Abstract Article PDF–5.1M

Select item 34717525.

Inactivation of Pyruvate Dehydrogenase Kinase 2 by Mitochondrial Reactive Oxygen Species

Thomas R. Hurd, Yvonne Collins, Irina Abakumova, Edward T. Chouchani, Bartlomiej Baranowski, Ian M. Fearnley, Tracy A. Prime, Michael P. Murphy, Andrew M. James

J Biol Chem. 2012 Oct 12; 287(42): 35153–35160. Published online 2012 Aug 21. doi: 10.1074/jbc.M112.400002

PMCID:: PMC3471752

Abstract Article PDF–1.1M

Select item 30237706.

Chronic CSE Treatment Induces the Growth of Normal Oral Keratinocytes via PDK2 Upregulation, Increased Glycolysis and HIF1α Stabilization

Wenyue Sun, Steven S. Chang, Yumei Fu, Yan Liu, Joseph A. Califano

PLoS One. 2011; 6(1): e16207. Published online 2011 Jan 19. doi: 10.1371/journal.pone.0016207

PMCID:: PMC3023770

Abstract Article PDF–526K

Select item 27972137.

Pivotal Role of the C-terminal DW-motif in Mediating Inhibition of Pyruvate Dehydrogenase Kinase 2 by Dichloroacetate

Jun Li, Masato Kato, David T. Chuang

J Biol Chem. 2009 Dec 4; 284(49): 34458–34467. Published online 2009 Oct 15. doi: 10.1074/jbc.M109.065557

PMCID:: PMC2797213

Abstract Article PDF–2.4M

Select item 12231288.

Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone.

Mark J Holness, Karen Bulmer, Nicholas D Smith, Mary C Sugden

Biochem J. 2003 Feb 1; 369(Pt 3): 687–695. doi: 10.1042/BJ20021509

PMCID:: PMC1223128

Summary PDF–249K

Select item 12208979.

Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression.

M C Sugden, A Kraus, R A Harris, M J Holness

Biochem J. 2000 Mar 15; 346(Pt 3): 651–657.

PMCID:: PMC1220897

Summary PDF–177K

Select item 121903110.

Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex.

M M Bowker-Kinley, W I Davis, P Wu, R A Harris, K M Popov

Biochem J. 1998 Jan 1; 329(Pt 1): 191–196. doi: 10.1042/bj3290191

PMCID:: PMC1219031

Summary PDF–219K

Select item 478673311.

Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy

Md Habibur Rahman, Mithilesh Kumar Jha, Jong-Heon Kim, Youngpyo Nam, Maan Gee Lee, Younghoon Go, Robert A. Harris, Dong Ho Park, Hyun Kook, In-Kyu Lee, Kyoungho Suk

J Biol Chem. 2016 Mar 11; 291(11): 6011–6025. Published online 2016 Jan 14. doi: 10.1074/jbc.M115.699215

PMCID:: PMC4786733

Abstract Article PDF–3.1M

Select item 432316112.

Fasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout mice

Nam Ho Jeoung, Yasmeen Rahimi, Pengfei Wu, W. N. Paul Lee, Robert A. Harris

Biochem J. Author manuscript; available in PMC 2015 Feb 10.

Published in final edited form as: Biochem J. 2012 May 1; 443(3): 829–839. doi: 10.1042/BJ20112197

PMCID:: PMC4323161

Abstract Article PDF–437K

Select item 1113625313.

Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer

T. E. Roche, Y. Hiromasa

Cell Mol Life Sci. 2007 Apr; 64(7-8): 830. Published online 2007 Feb 19. doi: 10.1007/s00018-007-6380-z

PMCID:: PMC11136253

Abstract Article PDF–855K

Select item 122203314.

Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites.

E Kolobova, A Tuganova, I Boulatnikov, K M Popov

Biochem J. 2001 Aug 15; 358(Pt 1): 69–77. doi: 10.1042/0264-6021:3580069

PMCID:: PMC1222033

Summary PDF–195K

Select item 637421015.

Structural Analysis of Hippocampal Kinase Signal Transduction

Daniel B. McClatchy, Nam-Kyung Yu, Salvador Martínez-Bartolomé, Reesha Patel, Alexander R. Pelletier, Mathieu Lavalle-Adam, Susan B. Powell, Marissa Roberto, John R. Yates

ACS Chem Neurosci. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: ACS Chem Neurosci. 2018 Dec 19; 9(12): 3072–3085. Published online 2018 Aug 13. doi: 10.1021/acschemneuro.8b00284

PMCID:: PMC6374210

Abstract Article PDF–1.4M

Select item 277884416.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016