PMC Links for Gene (Select 81537) - PMC

Select item 32250061.

Pericyte Derived Sphinogosine 1-Phosphate Induces the Expression of Adhesion Proteins and Modulates the Retinal Endothelial Cell Barrier

P.G. McGuire, S. Rangasamy, J. Maestas, A. Das

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2011 Dec; 31(12): e107–e115. Published online 2011 Sep 22. doi: 10.1161/ATVBAHA.111.235408

PMCID:: PMC3225006

Abstract Article PDF–467K

Select item 89737082.

MicroRNA-656-3p inhibits colorectal cancer cell migration, invasion, and chemo-resistance by targeting sphingosine-1-phosphate phosphatase 1

Baoming Zhang, Shanting Gao, Zengtao Bao, Cheng Pan, Qingshui Tian, Qiang Tang

Bioengineered. 2022; 13(2): 3810–3826. Published online 2022 Jan 26. doi: 10.1080/21655979.2022.2031420

PMCID:: PMC8973708

Abstract Article PDF–3.6M

Select item 76103143.

Sevoflurane suppresses cell viability and invasion and promotes cell apoptosis in colon cancer by modulating exosome-mediated circ-HMGCS1 via the miR-34a-5p/SGPP1 axis

Juan He, Huaping Zhao, Xing Liu, Dongmei Wang, Yong Wang, Yanqiu Ai, Jianjun Yang

Oncol Rep. 2020 Dec; 44(6): 2429–2442. Published online 2020 Sep 29. doi: 10.3892/or.2020.7783

PMCID:: PMC7610314

Abstract Article PDF–2.4M

Select item 57425144.

Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells

Anja Schwiebs, Dominique Thomas, Burkhard Kleuser, Josef M. Pfeilschifter, Heinfried H. Radeke

Mediators Inflamm. 2017; 2017: 5187368. Published online 2017 Dec 11. doi: 10.1155/2017/5187368

PMCID:: PMC5742514

Abstract Article PDF–2.3M

Select item 32479605.

Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

Sandrine Lépine, Jeremy C. Allegood, Yvette Edmonds, Sheldon Milstien, Sarah Spiegel

J Biol Chem. 2011 Dec 30; 286(52): 44380–44390. Published online 2011 Nov 3. doi: 10.1074/jbc.M111.257519

PMCID:: PMC3247960

Abstract Article PDF–4.0M

Select item 14891786.

Sphingosine-1-Phosphate Phosphohydrolase Regulates Endoplasmic Reticulum-to-Golgi Trafficking of Ceramide

Paola Giussani, Michael Maceyka, Hervé Le Stunff, Aki Mikami, Sandrine Lépine, Elaine Wang, Samuel Kelly, Alfred H. Merrill, Jr., Sheldon Milstien, Sarah Spiegel

Mol Cell Biol. 2006 Jul; 26(13): 5055–5069. doi: 10.1128/MCB.02107-05

PMCID:: PMC1489178

Abstract Article PDF–1.3M

Select item 31318827.

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

S Lépine, J C Allegood, M Park, P Dent, S Milstien, S Spiegel

Cell Death Differ. 2011 Feb; 18(2): 350–361. Published online 2010 Aug 27. doi: 10.1038/cdd.2010.104

PMCID:: PMC3131882

Abstract Article PDF–398K

Select item 27455628.

Genetic Determinants of Circulating Sphingolipid Concentrations in European Populations

Andrew A. Hicks, Peter P. Pramstaller, Åsa Johansson, Veronique Vitart, Igor Rudan, Peter Ugocsai, Yurii Aulchenko, Christopher S. Franklin, Gerhard Liebisch, Jeanette Erdmann, Inger Jonasson, Irina V. Zorkoltseva, Cristian Pattaro, Caroline Hayward, Aaron Isaacs, Christian Hengstenberg, Susan Campbell, Carsten Gnewuch, A. CecileJ.W. Janssens, Anatoly V. Kirichenko, Inke R. König, Fabio Marroni, Ozren Polasek, Ayse Demirkan, Ivana Kolcic, Christine Schwienbacher, Wilmar Igl, Zrinka Biloglav, Jacqueline C. M. Witteman, Irene Pichler, Ghazal Zaboli, Tatiana I. Axenovich, Annette Peters, Stefan Schreiber, H.-Erich Wichmann, Heribert Schunkert, Nick Hastie, Ben A. Oostra, Sarah H. Wild, Thomas Meitinger, Ulf Gyllensten, Cornelia M. van Duijn, James F. Wilson, Alan Wright, Gerd Schmitz, Harry Campbell

PLoS Genet. 2009 Oct; 5(10): e1000672. Published online 2009 Oct 2. doi: 10.1371/journal.pgen.1000672

PMCID:: PMC2745562

Abstract Article PDF–604K

Select item 41483949.

Tumor Suppressor MicroRNA-27a in Colorectal Carcinogenesis and Progression by Targeting SGPP1 and Smad2

Yonghua Bao, Zhiguo Chen, Yongchen Guo, Yansheng Feng, Zexin Li, Wenliang Han, Jianguo Wang, Weixing Zhao, Yunjuan Jiao, Kai Li, Qian Wang, Jiaqi Wang, Huijuan Zhang, Liang Wang, Wancai Yang

PLoS One. 2014; 9(8): e105991. Published online 2014 Aug 28. doi: 10.1371/journal.pone.0105991

Expression of Concern in:: PLoS One. 2023; 18(1): e0280980.

PMCID:: PMC4148394

Abstract Article PDF–3.2M

Select item 1663510.

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

Suzanne M. Mandala, Rosemary Thornton, Ismael Galve-Roperh, Samantha Poulton, Courtney Peterson, Ana Olivera, James Bergstrom, Myra B. Kurtz, Sarah Spiegel

Proc Natl Acad Sci U S A. 2000 Jul 5; 97(14): 7859–7864. Published online 2000 Jun 20. doi: 10.1073/pnas.120146897

PMCID:: PMC16635

Abstract Article PDF–244K

Select item 328096811.

Genome-Wide Association Study Identifies Novel Loci Associated with Circulating Phospho- and Sphingolipid Concentrations

Ayşe Demirkan, Cornelia M. van Duijn, Peter Ugocsai, Aaron Isaacs, Peter P. Pramstaller, Gerhard Liebisch, James F. Wilson, Åsa Johansson, Igor Rudan, Yurii S. Aulchenko, Anatoly V. Kirichenko, A. Cecile J. W. Janssens, Ritsert C. Jansen, Carsten Gnewuch, Francisco S. Domingues, Cristian Pattaro, Sarah H. Wild, Inger Jonasson, Ozren Polasek, Irina V. Zorkoltseva, Albert Hofman, Lennart C. Karssen, Maksim Struchalin, James Floyd, Wilmar Igl, Zrinka Biloglav, Linda Broer, Arne Pfeufer, Irene Pichler, Susan Campbell, Ghazal Zaboli, Ivana Kolcic, Fernando Rivadeneira, Jennifer Huffman, Nicholas D. Hastie, Andre Uitterlinden, Lude Franke, Christopher S. Franklin, Veronique Vitart, DIAGRAM Consortium, Christopher P. Nelson, Michael Preuss, CARDIoGRAM Consortium, Joshua C. Bis, Christopher J. O'Donnell, Nora Franceschini, CHARGE Consortium, Jacqueline C. M. Witteman, Tatiana Axenovich, Ben A. Oostra, Thomas Meitinger, Andrew A. Hicks, Caroline Hayward, Alan F. Wright, Ulf Gyllensten, Harry Campbell, Gerd Schmitz, on behalf of the EUROSPAN consortium

PLoS Genet. 2012 Feb; 8(2): e1002490. Published online 2012 Feb 16. doi: 10.1371/journal.pgen.1002490

PMCID:: PMC3280968

Abstract Article PDF–592K

Select item 406425412.

An atlas of genetic influences on human blood metabolites

So-Youn Shin, Eric B. Fauman, Ann-Kristin Petersen, Jan Krumsiek, Rita Santos, Jie Huang, Matthias Arnold, Idil Erte, Vincenzo Forgetta, Tsun-Po Yang, Klaudia Walter, Cristina Menni, Lu Chen, Louella Vasquez, Ana M. Valdes, Craig L. Hyde, Vicky Wang, Daniel Ziemek, Phoebe Roberts, Li Xi, Elin Grundberg, The Multiple Tissue Human Expression Resource (MuTHER) Consortium, Melanie Waldenberger, J. Brent Richards, Robert P. Mohney, Michael V. Milburn, Sally L. John, Jeff Trimmer, Fabian J. Theis, John P. Overington, Karsten Suhre, M. Julia Brosnan, Christian Gieger, Gabi Kastenmüller, Tim D Spector, Nicole Soranzo

Nat Genet. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Nat Genet. 2014 Jun; 46(6): 543–550. Published online 2014 May 11. doi: 10.1038/ng.2982

PMCID:: PMC4064254

Abstract Article PDF–2.4M

Select item 268304713.

Ubiquitin-mediated proteolysis of HuR by heat shock

Kotb Abdelmohsen, Subramanya Srikantan, Xiaoling Yang, Ashish Lal, Hyeon Ho Kim, Yuki Kuwano, Stefanie Galban, Kevin G Becker, Davida Kamara, Rafael de Cabo, Myriam Gorospe

EMBO J. 2009 May 6; 28(9): 1271–1282. Published online 2009 Mar 26. doi: 10.1038/emboj.2009.67

PMCID:: PMC2683047

Abstract Article PDF–1.4M

Select item 1023742214.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011