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Select item 106588901.

TMUB1 expression is associated with the prognosis of colon cancer and immune cell infiltration

Yan Lu, Kang Wang, Yuanhong Peng, Jun Zhang, Qinuo Ju, Qihuan Xu, Manzhao Ouyang, Zhiwei He

PeerJ. 2023; 11: e16334. Published online 2023 Nov 17. doi: 10.7717/peerj.16334

PMCID:: PMC10658890

Abstract Article PDF–18M

Select item 102145702.

Inhibition of TMUB1 blocks apoptosis and NF‐κB pathway‐mediated inflammation in recurrent spontaneous abortion

Xiuping Zhang, Yuanjing Hu, Zhiping Zhang, Xueluo Zhang, Lixia Liang, Xiangrong Cui, Yuanxia Wu, Fen Hu, Xueqing Wu

Immun Inflamm Dis. 2023 May; 11(5): e879. Published online 2023 May 26. doi: 10.1002/iid3.879

PMCID:: PMC10214570

Abstract Article PDF–3.8M

Select item 93457313.

Tao Hao, Hanqiang Yu, Daqi Huang, Qian Liu

Dis Markers. 2022; 2022: 5884531. Published online 2022 Jul 26. doi: 10.1155/2022/5884531

PMCID:: PMC9345731

Abstract Article PDF–2.6M

Select item 40025474.

Cloning and Characterization of DULP, a Novel Ubiquitin-Like Molecule from Human Dendritic Cells

Guoyan Liu, Shuxun Liu, Ping Li, Ling Tang, Yanmei Han, Huazhang An, Jiangyan Li, Xiankun Dai, Nan Li, Xuetao Cao, Yizhi Yu

Cell Mol Immunol. 2009 Feb; 6(1): 27–33. doi: 10.1038/cmi.2009.4

PMCID:: PMC4002547

Summary PDF–2.6M

Select item 69272395.

Transmembrane and Ubiquitin-Like Domain Containing 1 Protein (TMUB1) Negatively Regulates Hepatocellular Carcinoma Proliferation via Regulating Signal Transducer and Activator of Transcription 1 (STAT1)

Yin Chen, Hangwei Fu, Yida Zhang, Ping Chen

Med Sci Monit. 2019; 25: 9471–9482. Published online 2019 Dec 12. doi: 10.12659/MSM.920319

PMCID:: PMC6927239

Abstract Article PDF–4.2M

Select item 70015026.

HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53‐dependent mitochondrial apoptosis

Marilena Castelli, Danilo Piobbico, Martina Chiacchiaretta, Cinzia Brunacci, Stefania Pieroni, Daniela Bartoli, Marco Gargaro, Francesca Fallarino, Paolo Puccetti, Silvia Soddu, Maria Agnese Della‐Fazia, Giuseppe Servillo

EMBO Rep. 2020 Feb 5; 21(2): e48073. Published online 2019 Dec 23. doi: 10.15252/embr.201948073

PMCID:: PMC7001502

Abstract Article PDF–2.3M

Select item 28898387.

Transmembrane and Ubiquitin-Like Domain Containing 1 (Tmub1) Regulates Locomotor Activity and Wakefulness in Mice and Interacts with CAMLG

Wandong Zhang, Katerina V. Savelieva, Adisak Suwanichkul, Daniel L. Small, Laura L. Kirkpatrick, Nianhua Xu, Thomas H. Lanthorn, Gui-Lan Ye

PLoS One. 2010; 5(6): e11261. Published online 2010 Jun 22. doi: 10.1371/journal.pone.0011261

PMCID:: PMC2889838

Abstract Article PDF–998K

Select item 75670748.

HOPS/Tmub1 involvement in the NF-kB-mediated inflammatory response through the modulation of TRAF6

Marina Maria Bellet, Stefania Pieroni, Marilena Castelli, Danilo Piobbico, Francesca Fallarino, Luigina Romani, Maria Agnese Della-Fazia, Giuseppe Servillo

Cell Death Dis. 2020 Oct; 11(10): 865. Published online 2020 Oct 15. doi: 10.1038/s41419-020-03086-5

PMCID:: PMC7567074

Abstract Article PDF–1.7M

Select item 39062459.

Different functions of HOPS isoforms in the cell: HOPS shuttling isoform is determined by RIP cleavage system

Marilena Castelli, Danilo Piobbico, Daniela Bartoli, Stefania Pieroni, Cinzia Brunacci, Marina Maria Bellet, Martina Chiacchiaretta, Maria Agnese Della Fazia, Giuseppe Servillo

Cell Cycle. 2014 Jan 15; 13(2): 293–302. Published online 2013 Feb 1. doi: 10.4161/cc.27054

PMCID:: PMC3906245

Abstract Article PDF–4.9M

Select item 308320710.

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

Youngah Jo, Peter V. Sguigna, Russell A. DeBose-Boyd

J Biol Chem. 2011 Apr 29; 286(17): 15022–15031. Published online 2011 Feb 22. doi: 10.1074/jbc.M110.211326

PMCID:: PMC3083207

Abstract Article PDF–1.4M

Select item 748243311.

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

Michael L. van de Weijer, Logesvaran Krshnan, Sabrina Liberatori, Elena Navarro Guerrero, Jacob Robson-Tull, Lilli Hahn, Robert Jan Lebbink, Emmanuel J.H.J. Wiertz, Roman Fischer, Daniel Ebner, Pedro Carvalho

Mol Cell. 2020 Sep 3; 79(5): 768–781.e7. doi: 10.1016/j.molcel.2020.07.009

Correction in:: Mol Cell. 2020 Oct 15; 80(2): 374–375.

PMCID:: PMC7482433

Abstract Article

Select item 966343312.

Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation

Chengyu Shi, Ying Wang, Minjie Wu, Yu Chen, Fangzhou Liu, Zheyuan Shen, Yiran Wang, Shaofang Xie, Yingying Shen, Lingjie Sang, Zhen Zhang, Zerui Gao, Luojia Yang, Lei Qu, Zuozhen Yang, Xinyu He, Yu Guo, Chenghao Pan, Jinxin Che, Huaiqiang Ju, Jian Liu, Zhijian Cai, Qingfeng Yan, Luyang Yu, Liangjing Wang, Xiaowu Dong, Pinglong Xu, Jianzhong Shao, Yang Liu, Xu Li, Wenqi Wang, Ruhong Zhou, Tianhua Zhou, Aifu Lin

Nat Commun. 2022; 13: 6951. Published online 2022 Nov 14. doi: 10.1038/s41467-022-34346-x

PMCID:: PMC9663433

Abstract Article PDF–4.4M

Select item 727904913.

EDEM1 Drives Misfolded Protein Degradation via ERAD and Exploits ER-Phagy as Back-Up Mechanism When ERAD Is Impaired

Marioara Chiritoiu, Gabriela N. Chiritoiu, Cristian V. A. Munteanu, Florin Pastrama, N. Erwin Ivessa, Stefana M. Petrescu

Int J Mol Sci. 2020 May; 21(10): 3468. Published online 2020 May 14. doi: 10.3390/ijms21103468

PMCID:: PMC7279049

Abstract Article PDF–12M

Select item 542795014.

Novel, Gel-free Proteomics Approach Identifies RNF5 and JAMP as Modulators of GPCR Stability

Sébastien J. Roy, Irina Glazkova, Louis Fréchette, Christian Iorio-Morin, Chantal Binda, Darlaine Pétrin, Phan Trieu, Mélanie Robitaille, Stéphane Angers, Terence E. Hébert, Jean-Luc Parent

Mol Endocrinol. 2013 Aug; 27(8): 1245–1266. Published online 2013 Jun 24. doi: 10.1210/me.2013-1091

PMCID:: PMC5427950

Abstract Article

Select item 325047915.

Defining human ERAD networks through an integrative mapping strategy

John C. Christianson, James A. Olzmann, Thomas A. Shaler, Mathew E. Sowa, Eric J. Bennett, Caleb M. Richter, Ryan E. Tyler, Ethan J. Greenblatt, J. Wade Harper, Ron R. Kopito

Nat Cell Biol. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Nat Cell Biol. 2012 Jan; 14(1): 93–105. Published online 2011 Nov 27. doi: 10.1038/ncb2383

PMCID:: PMC3250479

Abstract Article PDF–2.7M

Select item 733229316.

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson

eLife. 2020; 9: e57306. Published online 2020 Jul 2. doi: 10.7554/eLife.57306

PMCID:: PMC7332293

Abstract Article PDF–2.2M

Select item 787370117.

Global proteomics of Ubqln2-based murine models of ALS

Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley

J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960

PMCID:: PMC7873701

Abstract Article PDF–3.0M

Select item 737304818.

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis

Jingjiao Li, Mingquan Guo, Xiaoxu Tian, Xin Wang, Xing Yang, Ping Wu, Chengrong Liu, Zixuan Xiao, Yafei Qu, Yue Yin, Chunxia Wang, Yucai Zhang, Zhaoqin Zhu, Zhenshan Liu, Chao Peng, Tongyu Zhu, Qiming Liang

Med (N Y) 2021 Jan 15; 2(1): 99–112.e7. Published online 2020 Jul 21. doi: 10.1016/j.medj.2020.07.002

PMCID:: PMC7373048

Abstract Article PDF–3.8M

Select item 875541919.

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation

Yuzheng Zhou, Rong Zheng, Sixu Liu, Cyrollah Disoma, Ashuai Du, Shiqin Li, Zongpeng Chen, Zijun Dong, Yongxing Zhang, Sijia Li, Pinjia Liu, Aroona Razzaq, Xuan Chen, Yujie Liao, Siyi Tao, Yuxin Liu, Lunan Xu, Qianjun Zhang, Jian Peng, Xu Deng, Shanni Li, Taijiao Jiang, Zanxian Xia

J Biol Chem. 2022 Feb; 298(2): 101584. Published online 2022 Jan 13. doi: 10.1016/j.jbc.2022.101584

PMCID:: PMC8755419

Abstract Article PDF–3.5M

Select item 288296120.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

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