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Select item 30860131.

Seipin Is a Discrete Homooligomer

Derk Binns, SungKyung Lee, Christopher L. Hilton, Qiu-Xing Jiang, Joel M. Goodman

Biochemistry. Author manuscript; available in PMC 2011 Jun 21.

Published in final edited form as: Biochemistry. 2010 Dec 21; 49(50): 10747–10755. Published online 2010 Nov 18. doi: 10.1021/bi1013003

PMCID:: PMC3086013

Abstract Article PDF–1.7M

Select item 93656732.

Seipin concentrates distinct neutral lipids via interactions with their acyl chain carboxyl esters

Mike F. Renne, Robin A. Corey, Joana Veríssimo Ferreira, Phillip J. Stansfeld, Pedro Carvalho

J Cell Biol. 2022 Sep 5; 221(9): e202112068. Published online 2022 Aug 8. doi: 10.1083/jcb.202112068

PMCID:: PMC9365673

Abstract Article PDF–5.9M

Select item 85010773.

Mechanism of lipid droplet formation by the yeast Sei1/Ldb16 Seipin complex

Yoel A. Klug, Justin C. Deme, Robin A. Corey, Mike F. Renne, Phillip J. Stansfeld, Susan M. Lea, Pedro Carvalho

Nat Commun. 2021; 12: 5892. Published online 2021 Oct 8. doi: 10.1038/s41467-021-26162-6

PMCID:: PMC8501077

Abstract Article PDF–3.4M

Select item 68296584.

Seipin negatively regulates sphingolipid production at the ER–LD contact site

Wei-Cheng Su, Yi-Hsiu Lin, Martin Pagac, Chao-Wen Wang

J Cell Biol. 2019 Nov 4; 218(11): 3663–3680. Published online 2019 Oct 8. doi: 10.1083/jcb.201902072

PMCID:: PMC6829658

Abstract Article PDF–4.4M

Select item 22342265.

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

Weihua Fei, Guanghou Shui, Bruno Gaeta, Ximing Du, Lars Kuerschner, Peng Li, Andrew J. Brown, Markus R. Wenk, Robert G. Parton, Hongyuan Yang

J Cell Biol. 2008 Feb 11; 180(3): 473–482. doi: 10.1083/jcb.200711136

PMCID:: PMC2234226

Abstract Article PDF–2.2M

Select item 72065456.

Synchrotron multimodal imaging in a whole cell reveals lipid droplet core organization

Frédéric Jamme, Bertrand Cinquin, Yann Gohon, Eva Pereiro, Matthieu Réfrégiers, Marine Froissard

J Synchrotron Radiat. 2020 May 1; 27(Pt 3): 772–778. Published online 2020 Apr 23. doi: 10.1107/S1600577520003847

PMCID:: PMC7206545

Abstract Article PDF–660K

Select item 46571627.

The seipin complex Fld1/Ldb16 stabilizes ER–lipid droplet contact sites

Alexandra Grippa, Laura Buxó, Gabriel Mora, Charlotta Funaya, Fatima-Zahra Idrissi, Francesco Mancuso, Raul Gomez, Júlia Muntanyà, Eduard Sabidó, Pedro Carvalho

J Cell Biol. 2015 Nov 23; 211(4): 829–844. doi: 10.1083/jcb.201502070

PMCID:: PMC4657162

Abstract Article PDF–6.9M

Select item 38241948.

The emergence of lipid droplets in yeast: current status and experimental approaches

Maja Radulovic, Oskar Knittelfelder, Alvaro Cristobal-Sarramian, Dagmar Kolb, Heimo Wolinski, Sepp D. Kohlwein

Curr Genet. 2013; 59(4): 231–242. Published online 2013 Sep 21. doi: 10.1007/s00294-013-0407-9

PMCID:: PMC3824194

Abstract Article PDF–1.5M

Select item 24092379.

The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology

Kimberly M. Szymanski, Derk Binns, René Bartz, Nick V. Grishin, Wei-Ping Li, Anil K. Agarwal, Abhimanyu Garg, Richard G. W. Anderson, Joel M. Goodman

Proc Natl Acad Sci U S A. 2007 Dec 26; 104(52): 20890–20895. Published online 2007 Dec 18. doi: 10.1073/pnas.0704154104

PMCID:: PMC2409237

Abstract Article PDF–1.1M

Select item 432584210.

Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology

Bethany R. Cartwright, Derk D. Binns, Christopher L. Hilton, Sungwon Han, Qiang Gao, Joel M. Goodman

Mol Biol Cell. 2015 Feb 15; 26(4): 726–739. doi: 10.1091/mbc.E14-08-1303

PMCID:: PMC4325842

Abstract Article PDF–2.9M

Select item 837487111.

Pex30-like proteins function as adaptors at distinct ER membrane contact sites

Joana Veríssimo Ferreira, Pedro Carvalho

J Cell Biol. 2021 Oct 4; 220(10): e202103176. Published online 2021 Aug 17. doi: 10.1083/jcb.202103176

PMCID:: PMC8374871

Abstract Article PDF–5.1M

Select item 606390512.

Seipin and the membrane-shaping protein Pex30 cooperate in organelle budding from the endoplasmic reticulum

Sihui Wang, Fatima-Zahra Idrissi, Martin Hermansson, Alexandra Grippa, Christer S. Ejsing, Pedro Carvalho

Nat Commun. 2018; 9: 2939. Published online 2018 Jul 27. doi: 10.1038/s41467-018-05278-2

PMCID:: PMC6063905

Abstract Article PDF–4.0M

Select item 574898113.

Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation

Michal Eisenberg-Bord, Muriel Mari, Uri Weill, Eden Rosenfeld-Gur, Ofer Moldavski, Inês G. Castro, Krishnakant G. Soni, Nofar Harpaz, Tim P. Levine, Anthony H. Futerman, Fulvio Reggiori, Vytas A. Bankaitis, Maya Schuldiner, Maria Bohnert

J Cell Biol. 2018 Jan 2; 217(1): 269–282. doi: 10.1083/jcb.201704122

PMCID:: PMC5748981

Abstract Article PDF–2.7M

Select item 574898014.

Regulation of lipid droplets by metabolically controlled Ldo isoforms

Vitor Teixeira, Lisa Johnsen, Fernando Martínez-Montañés, Alexandra Grippa, Laura Buxó, Fatima-Zahra Idrissi, Christer S. Ejsing, Pedro Carvalho

J Cell Biol. 2018 Jan 2; 217(1): 127–138. doi: 10.1083/jcb.201704115

PMCID:: PMC5748980

Abstract Article PDF–1.7M

Select item 562653015.

Pet10p is a yeast perilipin that stabilizes lipid droplets and promotes their assembly

Qiang Gao, Derk D. Binns, Lisa N. Kinch, Nick V. Grishin, Natalie Ortiz, Xiao Chen, Joel M. Goodman

J Cell Biol. 2017 Oct 2; 216(10): 3199–3217. doi: 10.1083/jcb.201610013

PMCID:: PMC5626530

Abstract Article PDF–3.0M

Select item 738045516.

Lipid droplet biogenesis from specialized ER subdomains

Vineet Choudhary, Roger Schneiter

Microb Cell. 2020 Aug 3; 7(8): 218–221. Published online 2020 Jun 16. doi: 10.15698/mic2020.08.727

PMCID:: PMC7380455

Abstract Article PDF–889K

Select item 534172717.

Lipid droplets are central organelles for meiosis II progression during yeast sporulation

Tzu-Han Hsu, Rey-Huei Chen, Yun-Hsin Cheng, Chao-Wen Wang

Mol Biol Cell. 2017 Feb 1; 28(3): 440–451. doi: 10.1091/mbc.E16-06-0375

PMCID:: PMC5341727

Abstract Article PDF–7.1M

Select item 733750318.

Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis

Vineet Choudhary, Ola El Atab, Giulia Mizzon, William A. Prinz, Roger Schneiter

J Cell Biol. 2020 Jul 6; 219(7): e201910177. Published online 2020 Apr 29. doi: 10.1083/jcb.201910177

PMCID:: PMC7337503

Abstract Article PDF–7.9M

Select item 467049419.

Dissecting seipin function: the localized accumulation of phosphatidic acid at ER/LD junctions in the absence of seipin is suppressed by Sei1p^ΔNterm only in combination with Ldb16p

Sungwon Han, Derk D. Binns, Yu-Fang Chang, Joel M. Goodman

BMC Cell Biol. 2015; 16: 29. Published online 2015 Dec 4. doi: 10.1186/s12860-015-0075-3

PMCID:: PMC4670494

Abstract Article PDF–1.9M

Select item 314562320.

A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets

Weihua Fei, Guanghou Shui, Yuxi Zhang, Natalie Krahmer, Charles Ferguson, Tamar S. Kapterian, Ruby C. Lin, Ian W. Dawes, Andrew J. Brown, Peng Li, Xun Huang, Robert G. Parton, Markus R. Wenk, Tobias C. Walther, Hongyuan Yang

PLoS Genet. 2011 Jul; 7(7): e1002201. Published online 2011 Jul 28. doi: 10.1371/journal.pgen.1002201