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Select item 99329321.

The Get1/2 insertase forms a channel to mediate the insertion of tail-anchored proteins into the ER

Paul Heo, Jacob A. Culver, Jennifer Miao, Frederic Pincet, Malaiyalam Mariappan

Cell Rep. Author manuscript; available in PMC 2023 Feb 16.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111921. Published online 2022 Dec 28. doi: 10.1016/j.celrep.2022.111921

PMCID:: PMC9932932

Abstract Article PDF–1.6M

Select item 85302272.

Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion

Un Seng Chio, Yumeng Liu, SangYoon Chung, Woo Jun Shim, Sowmya Chandrasekar, Shimon Weiss, Shu-ou Shan

J Cell Biol. 2021 Nov 1; 220(11): e202103079. Published online 2021 Oct 6. doi: 10.1083/jcb.202103079

PMCID:: PMC8530227

Abstract Article PDF–6.3M

Select item 46958513.

Active Nuclear Import of Membrane Proteins Revisited

Justyna K. Laba, Anton Steen, Petra Popken, Alina Chernova, Bert Poolman, Liesbeth M. Veenhoff

Cells. 2015 Dec; 4(4): 653–673. Published online 2015 Oct 13. doi: 10.3390/cells4040653

PMCID:: PMC4695851

Abstract Article PDF–3.6M

Select item 43427544.

The Get1/2 Transmembrane Complex is an ER Membrane Protein Insertase

Fei Wang, Charlene Chan, Nicholas R. Weir, Vladimir Denic

Nature. Author manuscript; available in PMC 2015 Feb 28.

Published in final edited form as: Nature. 2014 Aug 28; 512(7515): 441–444. Published online 2014 Jul 20. doi: 10.1038/nature13471

PMCID:: PMC4342754

Abstract Article PDF–844K

Select item 36018245.

Structural Basis for Tail-Anchored Membrane Protein Biogenesis by the Get3-Receptor Complex

Susanne Stefer, Simon Reitz, Fei Wang, Klemens Wild, Yin-Yuin Pang, Daniel Schwarz, Jörg Bomke, Christopher Hein, Frank Löhr, Frank Bernhard, Vladimir Denic, Volker Dötsch, Irmgard Sinning

Science. Author manuscript; available in PMC 2013 Mar 19.

Published in final edited form as: Science. 2011 Aug 5; 333(6043): 758–762. Published online 2011 Jun 30. doi: 10.1126/science.1207125

PMCID:: PMC3601824

Abstract Article PDF–2.4M

Select item 40506156.

The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins

Voytek Okreglak, Peter Walter

Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22): 8019–8024. Published online 2014 May 12. doi: 10.1073/pnas.1405755111

PMCID:: PMC4050615

Abstract Article PDF–1.2M

Select item 39107867.

The Natural Diyne-Furan Fatty Acid EV-086 Is an Inhibitor of Fungal Delta-9 Fatty Acid Desaturation with Efficacy in a Model of Skin Dermatophytosis

Philipp Knechtle, Melanie Diefenbacher, Katrine B. V. Greve, Federico Brianza, Christophe Folly, Harald Heider, Museer A. Lone, Lisa Long, Jean-Philippe Meyer, Patrick Roussel, Mahmoud A. Ghannoum, Roger Schneiter, Alexandra S. Sorensen

Antimicrob Agents Chemother. 2014 Jan; 58(1): 455–466. doi: 10.1128/AAC.01443-13

PMCID:: PMC3910786

Abstract Article PDF–2.3M

Select item 37604978.

The mechanism of membrane-associated steps in tail-anchored protein insertion

Malaiyalam Mariappan, Agnieszka Mateja, Malgorzata Dobosz, Elia Bove, Ramanujan S. Hegde, Robert J. Keenan

Nature. Author manuscript; available in PMC 2013 Sep 3.

Published in final edited form as: Nature. 2011 Aug 24; 477(7362): 61–66. Published online 2011 Aug 24. doi: 10.1038/nature10362

PMCID:: PMC3760497

Abstract Article PDF–2.0M

Select item 42462799.

Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway

Michael E. Rome, Un Seng Chio, Meera Rao, Harry Gristick, Shu-ou Shan

Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46): E4929–E4935. Published online 2014 Nov 3. doi: 10.1073/pnas.1411284111

PMCID:: PMC4246279

Abstract Article PDF–1.4M

Select item 361400210.

The Mechanism of Tail Anchored Protein Insertion into the ER Membrane

Fei Wang, Andrew Whynot, Matthew Tung, Vladimir Denic

Mol Cell. Author manuscript; available in PMC 2013 Apr 2.

Published in final edited form as: Mol Cell. 2011 Sep 2; 43(5): 738–750. Published online 2011 Aug 11. doi: 10.1016/j.molcel.2011.07.020

PMCID:: PMC3614002

Abstract Article PDF–2.5M

Select item 902624011.

GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER

Shunsuke Matsumoto, Suzuka Ono, Saori Shinoda, Chika Kakuta, Satoshi Okada, Takashi Ito, Tomoyuki Numata, Toshiya Endo

J Cell Biol. 2022 Jun 6; 221(6): e202104076. Published online 2022 Apr 20. doi: 10.1083/jcb.202104076

PMCID:: PMC9026240

Abstract Article PDF–6.9M

Select item 733750812.

Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress

Nurulain Ho, Wei Sheng Yap, Jiaming Xu, Haoxi Wu, Jhee Hong Koh, Wilson Wen Bin Goh, Bhawana George, Shu Chen Chong, Stefan Taubert, Guillaume Thibault

J Cell Biol. 2020 Jul 6; 219(7): e201909165. Published online 2020 Apr 29. doi: 10.1083/jcb.201909165

PMCID:: PMC7337508

Abstract Article PDF–5.9M

Select item 533838213.

Loss of GET pathway orthologs in Arabidopsis thaliana causes root hair growth defects and affects SNARE abundance

Shuping Xing, Dietmar Gerald Mehlhorn, Niklas Wallmeroth, Lisa Yasmin Asseck, Ritwika Kar, Alessa Voss, Philipp Denninger, Vanessa Aphaia Fiona Schmidt, Markus Schwarzländer, York-Dieter Stierhof, Guido Grossmann, Christopher Grefen

Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): E1544–E1553. Published online 2017 Jan 17. doi: 10.1073/pnas.1619525114