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Select item 98124191.

Functional Significance of Angiotensin Receptor Type 2 in the Neuroplasticity of Autonomic Ganglia in (mRen2)27 Transgenic Hypertensive Rats

Berwin Singh Swami Vetha, Rachel Byrum, Kaisi Peele, Debra Diz, Azeez Aileru

J Cardiovasc Pharmacol. 2023 Jan; 81(1): 76–84. Published online 2022 Sep 16. doi: 10.1097/FJC.0000000000001368

PMCID:: PMC9812419

Abstract Article PDF–864K

Select item 93547962.

Advanced oxidation protein products induce annulus fibrosus cell senescence through a NOX4-dependent, MAPK-mediated pathway and accelerate intervertebral disc degeneration

Xiangheng Dai, Yu Chen, Zihan Yu, Congrui Liao, Zhongyuan Liu, Jianting Chen, Qian Wu

PeerJ. 2022; 10: e13826. Published online 2022 Aug 2. doi: 10.7717/peerj.13826

PMCID:: PMC9354796

Abstract Article PDF–36M

Select item 88091183.

NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria

Zhi-Yu Li, Ying Liu, Yue-Ying Wang, Xiang Li, Zhuo-Na Han, Lan Hong, Ying-Shun Li, Xun Cui

Mol Med Rep. 2022 Mar; 25(3): 84. Published online 2022 Jan 13. doi: 10.3892/mmr.2022.12600

PMCID:: PMC8809118

Abstract Article PDF–4.8M

Select item 83830394.

Protective effects of metformin against myocardial ischemia-reperfusion injury via AMPK-dependent suppression of NOX4

Yan Shi, Shu-Ai Hou

Mol Med Rep. 2021 Oct; 24(4): 712. Published online 2021 Aug 10. doi: 10.3892/mmr.2021.12351

PMCID:: PMC8383039

Abstract Article PDF–953K

Select item 77220425.

NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease

Tengis S. Pavlov, Oleg Palygin, Elena Isaeva, Vladislav Levchenko, Sherif Khedr, Gregory Blass, Daria V. Ilatovskaya, Allen W. Cowley, Jr., Alexander Staruschenko

FASEB J. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: FASEB J. 2020 Oct; 34(10): 13396–13408. Published online 2020 Aug 16. doi: 10.1096/fj.202000966RR

PMCID:: PMC7722042

Abstract Article PDF–1.1M

Select item 71753166.

Chronic Exposure to Fluoride Affects GSH Level and NOX4 Expression in Rat Model of This Element of Neurotoxicity

Karolina Dec, Agnieszka Łukomska, Karolina Skonieczna-Żydecka, Karolina Jakubczyk, Maciej Tarnowski, Anna Lubkowska, Irena Baranowska-Bosiacka, Daniel Styburski, Marta Skórka-Majewicz, Dominika Maciejewska, Izabela Gutowska

Biomolecules. 2020 Mar; 10(3): 422. Published online 2020 Mar 9. doi: 10.3390/biom10030422

PMCID:: PMC7175316

Abstract Article PDF–1.4M

Select item 71393167.

Oxidative Stress and Mitochondrial Abnormalities Contribute to Decreased Endothelial Nitric Oxide Synthase Expression and Renal Disease Progression in Early Experimental Polycystic Kidney Disease

Alp S. Kahveci, Tania T. Barnatan, Ali Kahveci, Alexis E. Adrian, Jennifer Arroyo, Alfonso Eirin, Peter C. Harris, Amir Lerman, Lilach O. Lerman, Vicente E. Torres, Maria V. Irazabal

Int J Mol Sci. 2020 Mar; 21(6): 1994. Published online 2020 Mar 14. doi: 10.3390/ijms21061994

PMCID:: PMC7139316

Abstract Article PDF–3.9M

Select item 68373968.

Systemic upregulation of NADPH oxidase in diet-induced obesity in rats

Fan Jiang, Han K Lim, Margaret J Morris, Larissa Prior, Elena Velkoska, Xiao Wu, Gregory J Dusting

Redox Rep. 2011; 16(6): 223–229. Published online 2013 Jul 19. doi: 10.1179/174329211X13049558293713

PMCID:: PMC6837396

Abstract Article PDF–303K

Select item 56329079.

Oxygen-Sensing Nox4 Generates Genotoxic ROS to Induce Premature Senescence of Nucleus Pulposus Cells through MAPK and NF-κB Pathways

Chencheng Feng, Yang Zhang, Minghui Yang, Minghong Lan, Huan Liu, Bo Huang, Yue Zhou

Oxid Med Cell Longev. 2017; 2017: 7426458. Published online 2017 Sep 24. doi: 10.1155/2017/7426458

PMCID:: PMC5632907

Abstract Article PDF–6.4M

Select item 502831210.

Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle

Maha Coucha, Mohammed Abdelsaid, Weiguo Li, Maribeth H. Johnson, Laszlo Orfi, Azza B. El-Remessy, Susan C. Fagan, Adviye Ergul

Life Sci. Author manuscript; available in PMC 2017 Oct 15.

Published in final edited form as: Life Sci. 2016 Oct 15; 163: 46–54. Published online 2016 Aug 21. doi: 10.1016/j.lfs.2016.08.018

PMCID:: PMC5028312

Abstract Article PDF–1.1M

Select item 481488111.

Luminal flow induces NADPH oxidase 4 translocation to the nuclei of thick ascending limbs

Fara Saez, Nancy J. Hong, Jeffrey L. Garvin

Physiol Rep. 2016 Mar; 4(6): e12724. Published online 2016 Mar 31. doi: 10.14814/phy2.12724

PMCID:: PMC4814881

Abstract Article PDF–1.1M

Select item 471330112.

EVIDENCE OF THE IMPORTANCE OF NOX4 IN PRODUCTION OF HYPERTENSION IN DAHL SALT-SENSITIVE RATS

Allen W. Cowley, Jr, Chun Yang, Nadezhda N. Zheleznova, Alexander Staruschenko, Theresa Kurth, Lisa Rein, Vikash Kumar, Katherine Sadovnikov, Alex Dayton, Matthew Hoffman, Robert P. Ryan, Meredith M. Skelton, Fahimeh Salehpour, Mahsa Ranji, Aron Geurts

Hypertension. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Hypertension. 2016 Feb; 67(2): 440–450. Published online 2015 Dec 7. doi: 10.1161/HYPERTENSIONAHA.115.06280

PMCID:: PMC4713301

Abstract Article PDF–1.7M

Select item 451744313.

Nox4 Oxidase Overexpression Specifically Decreases Endogenous Nox4 mRNA and Inhibits Angiotensin II–Induced Adventitial Myofibroblast Migration

Mounir J. Haurani, M. Eugenia Cifuentes, Alexander D. Shepard, Patrick J. Pagano

Hypertension. Author manuscript; available in PMC 2015 Jul 28.

Published in final edited form as: Hypertension. 2008 Jul; 52(1): 143–149. Published online 2008 May 12. doi: 10.1161/HYPERTENSIONAHA.107.101667

PMCID:: PMC4517443

Abstract Article PDF–403K

Select item 381424714.

Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes

Rita M. Maalouf, Assaad A. Eid, Yves C. Gorin, Karen Block, Gladys Patricia Escobar, Steven Bailey, Hanna E. Abboud

Am J Physiol Cell Physiol. 2012 Feb 1; 302(3): C597–C604. Published online 2011 Oct 26. doi: 10.1152/ajpcell.00331.2011

PMCID:: PMC3814247

Abstract Article

Select item 274481415.

Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy

Donald J. McCrann, Dan Yang, Hongjie Chen, Shannon Carroll, Katya Ravid

Cell Cycle. Author manuscript; available in PMC 2010 Mar 15.

Published in final edited form as: Cell Cycle. 2009 Mar 15; 8(6): 902–908. Published online 2009 Mar 21. doi: 10.4161/cc.8.6.7900

PMCID:: PMC2744814

Abstract Article PDF–675K

Select item 273286316.

Subcellular localization of Nox4 and regulation in diabetes

Karen Block, Yves Gorin, Hanna E. Abboud

Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34): 14385–14390. Published online 2009 Aug 17. doi: 10.1073/pnas.0906805106

PMCID:: PMC2732863

Abstract Article PDF–2.1M

Select item 271437617.

Green tea (Camellia sinensis) Attenuates Nephropathy by Downregulating Nox4 NADPH Oxidase in Diabetic Spontaneously Hypertensive Rats

Pérola D. B. Ribaldo, Denise S. Souza, Subrata K. Biswas, Karen Block, Jacqueline M. Lopes de Faria, José B. Lopes de Faria

J Nutr. 2009 Jan; 139(1): 96–100. doi: 10.3945/jn.108.095018

PMCID:: PMC2714376

Abstract Article PDF–657K

Select item 257459518.

Activation of microglia with zymosan promotes excitatory amino acid release via volume-regulated anion channels: the role of NADPH oxidases

Timothy J. Harrigan, Iskandar F. Abdullaev, David Jourd'heuil, Alexander A. Mongin

J Neurochem. Author manuscript; available in PMC 2009 Sep 1.

Published in final edited form as: J Neurochem. 2008 Sep; 106(6): 2449–2462. Published online 2008 Jul 9. doi: 10.1111/j.1471-4159.2008.05553.x

PMCID:: PMC2574595

Abstract Article PDF–833K

Select item 186857719.

Nox4 Is Required for Maintenance of the Differentiated Vascular Smooth Muscle Cell Phenotype

Roza E. Clempus, Dan Sorescu, Anna E. Dikalova, Lily Pounkova, Patricia Jo, George P. Sorescu, Bernard Lassègue, Kathy K. Griendling

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2007 May 14.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2007 Jan; 27(1): 42–48. Published online 2006 Nov 2. doi: 10.1161/01.ATV.0000251500.94478.18