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Select item 81894351.

Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase

Ka-Yiu Edwin Kong, Bernd Fischer, Matthias Meurer, Ilia Kats, Zhaoyan Li, Frank Rühle, Joseph D. Barry, Daniel Kirrmaier, Veronika Chevyreva, Bryan-Joseph San Luis, Michael Costanzo, Wolfgang Huber, Brenda J. Andrews, Charles Boone, Michael Knop, Anton Khmelinskii

Mol Cell. 2021 Jun 3; 81(11): 2460–2476.e11. doi: 10.1016/j.molcel.2021.04.018

PMCID:: PMC8189435

Abstract Article

Select item 34081642.

Exploring the Topology of the Gid Complex, the E3 Ubiquitin Ligase Involved in Catabolite-induced Degradation of Gluconeogenic Enzymes

Ruth Menssen, Jörg Schweiggert, Jens Schreiner, Denis Kušević, Julia Reuther, Bernhard Braun, Dieter H. Wolf

J Biol Chem. 2012 Jul 20; 287(30): 25602–25614. Published online 2012 May 29. doi: 10.1074/jbc.M112.363762

PMCID:: PMC3408164

Abstract Article PDF–3.5M

Select item 91600493.

Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation

Shuai Qiao, Chia-Wei Lee, Dawafuti Sherpa, Jakub Chrustowicz, Jingdong Cheng, Maximilian Duennebacke, Barbara Steigenberger, Ozge Karayel, Duc Tung Vu, Susanne von Gronau, Matthias Mann, Florian Wilfling, Brenda A. Schulman

Nat Commun. 2022; 13: 3041. Published online 2022 Jun 1. doi: 10.1038/s41467-022-30803-9

PMCID:: PMC9160049

Abstract Article PDF–3.0M

Select item 24882824.

The Yeast GID Complex, a Novel Ubiquitin Ligase (E3) Involved in the Regulation of Carbohydrate Metabolism

Olivier Santt, Thorsten Pfirrmann, Bernhard Braun, Jeannette Juretschke, Philipp Kimmig, Hartmut Scheel, Kay Hofmann, Michael Thumm, Dieter H. Wolf

Mol Biol Cell. 2008 Aug; 19(8): 3323–3333. doi: 10.1091/mbc.E08-03-0328

PMCID:: PMC2488282

Abstract Article PDF–1.9M

Select item 25934065.

A TSC22-like motif defines a novel antiapoptotic protein family

Chamel M Khoury, Zhao Yang, Xiao Yu Li, Marissa Vignali, Stanley Fields, Michael T Greenwood

FEMS Yeast Res. 2008 Jun; 8(4): 540–563. Published online 2008 Mar 18. doi: 10.1111/j.1567-1364.2008.00367.x

PMCID:: PMC2593406

Abstract Article PDF–1.2M

Select item 14624776.

A Saccharomyces cerevisiae genome-wide mutant screen for altered sensitivity to K1 killer toxin.

Nicolas Pagé, Manon Gérard-Vincent, Patrice Ménard, Maude Beaulieu, Masayuki Azuma, Gerrit J P Dijkgraaf, Huijuan Li, José Marcoux, Thuy Nguyen, Tim Dowse, Anne-Marie Sdicu, Howard Bussey

Genetics. 2003 Mar; 163(3): 875–894. doi: 10.1093/genetics/163.3.875

PMCID:: PMC1462477

Summary PDF–329K

Select item 1531297.

Catabolite Degradation of Fructose-1,6-bisphosphatase in the Yeast Saccharomyces cerevisiae: A Genome-wide Screen Identifies Eight Novel GID Genes and Indicates the Existence of Two Degradation Pathways

Jochen Regelmann, Thomas Schüle, Frank S. Josupeit, Jaroslav Horak, Matthias Rose, Karl-Dieter Entian, Michael Thumm, Dieter H. Wolf

Mol Biol Cell. 2003 Apr; 14(4): 1652–1663. doi: 10.1091/mbc.E02-08-0456

PMCID:: PMC153129

Abstract Article PDF–509K

Select item 91714108.

A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters

Christine R Langlois, Viola Beier, Ozge Karayel, Jakub Chrustowicz, Dawafuti Sherpa, Matthias Mann, Brenda A Schulman

EMBO Rep. 2022 Jun; 23(6): e53835. Published online 2022 Apr 19. doi: 10.15252/embr.202153835

PMCID:: PMC9171410

Abstract Article PDF–1.4M

Select item 35156169.

Regulation of Hxt3 and Hxt7 Turnover Converges on the Vid30 Complex and Requires Inactivation of the Ras/cAMP/PKA Pathway in Saccharomyces cerevisiae

Chris Snowdon, George van der Merwe

PLoS One. 2012; 7(12): e50458. Published online 2012 Dec 5. doi: 10.1371/journal.pone.0050458

PMCID:: PMC3515616

Abstract Article PDF–1.1M

Select item 155754110.

PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs

Sylvain Pitre, Frank Dehne, Albert Chan, Jim Cheetham, Alex Duong, Andrew Emili, Marinella Gebbia, Jack Greenblatt, Mathew Jessulat, Nevan Krogan, Xuemei Luo, Ashkan Golshani

BMC Bioinformatics. 2006; 7: 365. Published online 2006 Jul 27. doi: 10.1186/1471-2105-7-365

PMCID:: PMC1557541

Abstract Article PDF–984K

Select item 144879311.

Host Factors That Affect Ty3 Retrotransposition in Saccharomyces cerevisiae

Michael Aye, Becky Irwin, Nadejda Beliakova-Bethell, Eric Chen, Jennifer Garrus, Suzanne Sandmeyer

Genetics. 2004 Nov; 168(3): 1159–1176. doi: 10.1534/genetics.104.028126

PMCID:: PMC1448793

Abstract Article PDF–424K

Select item 422347512.

A Pipeline for Determining Protein–Protein Interactions and Proximities in the Cellular Milieu

Roman I. Subbotin, Brian T. Chait

Mol Cell Proteomics. 2014 Nov; 13(11): 2824–2835. Published online 2014 Aug 29. doi: 10.1074/mcp.M114.041095

PMCID:: PMC4223475

Abstract Article PDF–824K

Select item 315584113.

Global Functional Map of the p23 Molecular Chaperone Reveals an Extensive Cellular Network

Frank J. Echtenkamp, Elena Zelin, Ellinor Oxelmark, Joyce I. Woo, Brenda J. Andrews, Michael Garabedian, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2012 Jul 22.

Published in final edited form as: Mol Cell. 2011 Jul 22; 43(2): 229–241. doi: 10.1016/j.molcel.2011.05.029

PMCID:: PMC3155841

Abstract Article PDF–1.7M

Select item 260095614.

A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae

S. G. Addinall, M. Downey, M. Yu, M. K. Zubko, J. Dewar, A. Leake, J. Hallinan, O. Shaw, K. James, D. J. Wilkinson, A. Wipat, D. Durocher, D. Lydall

Genetics. 2008 Dec; 180(4): 2251–2266. doi: 10.1534/genetics.108.092577

PMCID:: PMC2600956

Abstract Article PDF–1.9M

Select item 307236815.

Quantitative Fitness Analysis Shows That NMD Proteins and Many Other Protein Complexes Suppress or Enhance Distinct Telomere Cap Defects

Stephen Gregory Addinall, Eva-Maria Holstein, Conor Lawless, Min Yu, Kaye Chapman, A. Peter Banks, Hien-Ping Ngo, Laura Maringele, Morgan Taschuk, Alexander Young, Adam Ciesiolka, Allyson Lurena Lister, Anil Wipat, Darren James Wilkinson, David Lydall

PLoS Genet. 2011 Apr; 7(4): e1001362. Published online 2011 Apr 7. doi: 10.1371/journal.pgen.1001362

PMCID:: PMC3072368

Abstract Article PDF–4.0M

Select item 751569416.

RNA-binding and prion domains: the Yin and Yang of phase separation

Nieves Lorenzo Gotor, Alexandros Armaos, Giulia Calloni, Marc Torrent Burgas, R Martin Vabulas, Natalia Sanchez De Groot, Gian Gaetano Tartaglia

Nucleic Acids Res. 2020 Sep 25; 48(17): 9491–9504. Published online 2020 Aug 28. doi: 10.1093/nar/gkaa681

PMCID:: PMC7515694

Abstract Article PDF–3.1M

Select item 611694917.

A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A

Sultan Ciftci-Yilmaz, Wei-Chun Au, Prashant K. Mishra, Jessica R. Eisenstatt, Joy Chang, Anthony R. Dawson, Iris Zhu, Mahfuzur Rahman, Sven Bilke, Michael Costanzo, Anastasia Baryshnikova, Chad L. Myers, Paul S. Meltzer, David Landsman, Richard E. Baker, Charles Boone, Munira A. Basrai

Genetics. 2018 Sep; 210(1): 203–218. Published online 2018 Jul 16. doi: 10.1534/genetics.118.301305

PMCID:: PMC6116949

Abstract Article PDF–2.1M

Select item 306367118.

A Genome-Wide Enhancer Screen Implicates Sphingolipid Composition in Vacuolar ATPase Function in Saccharomyces cerevisiae

Gregory C. Finnigan, Margret Ryan, Tom H. Stevens

Genetics. 2011 Mar; 187(3): 771–783. doi: 10.1534/genetics.110.125567

PMCID:: PMC3063671

Abstract Article PDF–1.5M

Select item 963802819.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536