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Select item 48305681.

The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence

Delma S. Childers, Ingrida Raziunaite, Gabriela Mol Avelar, Joanna Mackie, Susan Budge, David Stead, Neil A. R. Gow, Megan D. Lenardon, Elizabeth R. Ballou, Donna M. MacCallum, Alistair J. P. Brown

PLoS Pathog. 2016 Apr; 12(4): e1005566. Published online 2016 Apr 13. doi: 10.1371/journal.ppat.1005566

PMCID:: PMC4830568

Abstract Article PDF–2.3M

Select item 5390132.

Gid8p (Dcr1p) and Dcr2p Function in a Common Pathway To Promote START Completion in Saccharomyces cerevisiae

Ritu Pathak, Lydia M. Bogomolnaya, Jinbai Guo, Michael Polymenis

Eukaryot Cell. 2004 Dec; 3(6): 1627–1638. doi: 10.1128/EC.3.6.1627-1638.2004

PMCID:: PMC539013

Abstract Article PDF–742K

Select item 34081643.

Exploring the Topology of the Gid Complex, the E3 Ubiquitin Ligase Involved in Catabolite-induced Degradation of Gluconeogenic Enzymes

Ruth Menssen, Jörg Schweiggert, Jens Schreiner, Denis Kušević, Julia Reuther, Bernhard Braun, Dieter H. Wolf

J Biol Chem. 2012 Jul 20; 287(30): 25602–25614. Published online 2012 May 29. doi: 10.1074/jbc.M112.363762

PMCID:: PMC3408164

Abstract Article PDF–3.5M

Select item 91600494.

Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation

Shuai Qiao, Chia-Wei Lee, Dawafuti Sherpa, Jakub Chrustowicz, Jingdong Cheng, Maximilian Duennebacke, Barbara Steigenberger, Ozge Karayel, Duc Tung Vu, Susanne von Gronau, Matthias Mann, Florian Wilfling, Brenda A. Schulman

Nat Commun. 2022; 13: 3041. Published online 2022 Jun 1. doi: 10.1038/s41467-022-30803-9

PMCID:: PMC9160049

Abstract Article PDF–3.0M

Select item 24882825.

The Yeast GID Complex, a Novel Ubiquitin Ligase (E3) Involved in the Regulation of Carbohydrate Metabolism

Olivier Santt, Thorsten Pfirrmann, Bernhard Braun, Jeannette Juretschke, Philipp Kimmig, Hartmut Scheel, Kay Hofmann, Michael Thumm, Dieter H. Wolf

Mol Biol Cell. 2008 Aug; 19(8): 3323–3333. doi: 10.1091/mbc.E08-03-0328

PMCID:: PMC2488282

Abstract Article PDF–1.9M

Select item 1531296.

Catabolite Degradation of Fructose-1,6-bisphosphatase in the Yeast Saccharomyces cerevisiae: A Genome-wide Screen Identifies Eight Novel GID Genes and Indicates the Existence of Two Degradation Pathways

Jochen Regelmann, Thomas Schüle, Frank S. Josupeit, Jaroslav Horak, Matthias Rose, Karl-Dieter Entian, Michael Thumm, Dieter H. Wolf

Mol Biol Cell. 2003 Apr; 14(4): 1652–1663. doi: 10.1091/mbc.E02-08-0456

PMCID:: PMC153129

Abstract Article PDF–509K

Select item 91714107.

A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters

Christine R Langlois, Viola Beier, Ozge Karayel, Jakub Chrustowicz, Dawafuti Sherpa, Matthias Mann, Brenda A Schulman

EMBO Rep. 2022 Jun; 23(6): e53835. Published online 2022 Apr 19. doi: 10.15252/embr.202153835

PMCID:: PMC9171410

Abstract Article PDF–1.4M

Select item 35156168.

Regulation of Hxt3 and Hxt7 Turnover Converges on the Vid30 Complex and Requires Inactivation of the Ras/cAMP/PKA Pathway in Saccharomyces cerevisiae

Chris Snowdon, George van der Merwe

PLoS One. 2012; 7(12): e50458. Published online 2012 Dec 5. doi: 10.1371/journal.pone.0050458

PMCID:: PMC3515616

Abstract Article PDF–1.1M

Select item 15575419.

PIPE: a protein-protein interaction prediction engine based on the re-occurring short polypeptide sequences between known interacting protein pairs

Sylvain Pitre, Frank Dehne, Albert Chan, Jim Cheetham, Alex Duong, Andrew Emili, Marinella Gebbia, Jack Greenblatt, Mathew Jessulat, Nevan Krogan, Xuemei Luo, Ashkan Golshani

BMC Bioinformatics. 2006; 7: 365. Published online 2006 Jul 27. doi: 10.1186/1471-2105-7-365

PMCID:: PMC1557541

Abstract Article PDF–984K

Select item 365673710.

A Genetic Screen for High Copy Number Suppressors of the Synthetic Lethality Between elg1Δ and srs2Δ in Yeast

Inbal Gazy, Batia Liefshitz, Alex Bronstein, Oren Parnas, Nir Atias, Roded Sharan, Martin Kupiec

G3 (Bethesda) 2013 May; 3(5): 917–926. Published online 2013 May 1. doi: 10.1534/g3.113.005561

PMCID:: PMC3656737

Abstract Article PDF–1.0M

Select item 552679011.

PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response

Elisa Ferrari, Christopher Bruhn, Marta Peretti, Corinne Cassani, Walter Vincenzo Carotenuto, Mohamed Elgendy, Ghadeer Shubassi, Chiara Lucca, Rodrigo Bermejo, Mario Varasi, Saverio Minucci, Maria Pia Longhese, Marco Foiani

Mol Cell. 2017 Jul 20; 67(2): 266–281.e4. doi: 10.1016/j.molcel.2017.05.027

PMCID:: PMC5526790

Abstract Article

Select item 236684312.

The Clathrin Adaptor Gga2p Is a Phosphatidylinositol 4-phosphate Effector at the Golgi Exit

Lars Demmel, Maike Gravert, Ebru Ercan, Bianca Habermann, Thomas Müller-Reichert, Viktoria Kukhtina, Volker Haucke, Thorsten Baust, Marc Sohrmann, Yannis Kalaidzidis, Christian Klose, Mike Beck, Matthias Peter, Christiane Walch-Solimena

Mol Biol Cell. 2008 May; 19(5): 1991–2002. doi: 10.1091/mbc.E06-10-0937

PMCID:: PMC2366843

Abstract Article PDF–2.7M

Select item 422347513.

A Pipeline for Determining Protein–Protein Interactions and Proximities in the Cellular Milieu

Roman I. Subbotin, Brian T. Chait

Mol Cell Proteomics. 2014 Nov; 13(11): 2824–2835. Published online 2014 Aug 29. doi: 10.1074/mcp.M114.041095

PMCID:: PMC4223475

Abstract Article PDF–824K

Select item 353328614.

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors

Mahadeo A. Sukhai, Swayam Prabha, Rose Hurren, Angela C. Rutledge, Anna Y. Lee, Shrivani Sriskanthadevan, Hong Sun, Xiaoming Wang, Marko Skrtic, Ayesh Seneviratne, Maria Cusimano, Bozhena Jhas, Marcela Gronda, Neil MacLean, Eunice E. Cho, Paul A. Spagnuolo, Sumaiya Sharmeen, Marinella Gebbia, Malene Urbanus, Kolja Eppert, Dilan Dissanayake, Alexia Jonet, Alexandra Dassonville-Klimpt, Xiaoming Li, Alessandro Datti, Pamela S. Ohashi, Jeff Wrana, Ian Rogers, Pascal Sonnet, William Y. Ellis, Seth J. Corey, Connie Eaves, Mark D. Minden, Jean C.Y. Wang, John E. Dick, Corey Nislow, Guri Giaever, Aaron D. Schimmer

J Clin Invest. 2013 Jan 2; 123(1): 315–328. Published online 2012 Dec 3. doi: 10.1172/JCI64180

PMCID:: PMC3533286

Abstract Article PDF–2.1M

Select item 611694915.

A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A

Sultan Ciftci-Yilmaz, Wei-Chun Au, Prashant K. Mishra, Jessica R. Eisenstatt, Joy Chang, Anthony R. Dawson, Iris Zhu, Mahfuzur Rahman, Sven Bilke, Michael Costanzo, Anastasia Baryshnikova, Chad L. Myers, Paul S. Meltzer, David Landsman, Richard E. Baker, Charles Boone, Munira A. Basrai

Genetics. 2018 Sep; 210(1): 203–218. Published online 2018 Jul 16. doi: 10.1534/genetics.118.301305

PMCID:: PMC6116949

Abstract Article PDF–2.1M

Select item 575387316.

Protein Moonlighting Revealed by Noncatalytic Phenotypes of Yeast Enzymes

Adriana Espinosa-Cantú, Diana Ascencio, Selene Herrera-Basurto, Jiewei Xu, Assen Roguev, Nevan J. Krogan, Alexander DeLuna

Genetics. 2018 Jan; 208(1): 419–431. Published online 2017 Nov 10. doi: 10.1534/genetics.117.300377

PMCID:: PMC5753873

Abstract Article PDF–1.5M

Select item 443181017.

The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation

Lydia M. Castelli, David Talavera, Christopher J. Kershaw, Sarah S. Mohammad-Qureshi, Joseph L. Costello, William Rowe, Paul F. G. Sims, Christopher M. Grant, Simon J. Hubbard, Mark P. Ashe, Graham D. Pavitt

PLoS Genet. 2015 May; 11(5): e1005233. Published online 2015 May 14. doi: 10.1371/journal.pgen.1005233