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Items: 1 to 20 of 30

1.
Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C–related protein reveals a primordial role in subcellular sphingolipid distribution
Krishnamurthy Malathi, Katsumi Higaki, Arthur H. Tinkelenberg, Dina A. Balderes, Dorca Almanzar-Paramio, Lisa J. Wilcox, Naz Erdeniz, Francis Redican, Mahajabeen Padamsee, Ying Liu, Sohail Khan, Frederick Alcantara, Eugene D. Carstea, Jill A. Morris, Stephen L. Sturley
J Cell Biol. 2004 Feb 16; 164(4): 547–556. doi: 10.1083/jcb.200310046
PMCID:
PMC2171978
AbstractArticlePDF–486K
2.
Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann–Pick Type C1
Telma S. Martins, Rafaela S. Costa, Rita Vilaça, Carolina Lemos, Vitor Teixeira, Clara Pereira, Vítor Costa
Int J Mol Sci. 2023 Apr; 24(7): 6221. Published online 2023 Mar 25. doi: 10.3390/ijms24076221
PMCID:
PMC10094029
AbstractArticlePDF–1.7M
3.
Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole
Takuma Tsuji, Megumi Fujimoto, Tsuyako Tatematsu, Jinglei Cheng, Minami Orii, Sho Takatori, Toyoshi Fujimoto
eLife. 2017; 6: e25960. Published online 2017 Jun 7. doi: 10.7554/eLife.25960
PMCID:
PMC5462540
AbstractArticlePDF–7.8M
4.
An “Exacerbate-reverse” Strategy in Yeast Identifies Histone Deacetylase Inhibition as a Correction for Cholesterol and Sphingolipid Transport Defects in Human Niemann-Pick Type C Disease
Andrew B. Munkacsi, Fannie W. Chen, Matthew A. Brinkman, Katsumi Higaki, Giselle Domínguez Gutiérrez, Jagruti Chaudhari, Jacob V. Layer, Amy Tong, Martin Bard, Charles Boone, Yiannis A. Ioannou, Stephen L. Sturley
J Biol Chem. 2011 Jul 8; 286(27): 23842–23851. Published online 2011 Apr 13. doi: 10.1074/jbc.M111.227645
PMCID:
PMC3129166
AbstractArticlePDF–3.5M
5.
The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1
Rita Vilaça, Ivo Barros, Nabil Matmati, Elísio Silva, Telma Martins, Vítor Teixeira, Yusuf A. Hannun, Vítor Costa
Biochim Biophys Acta. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2018 Jan; 1864(1): 79–88. Published online 2017 Oct 6. doi: 10.1016/j.bbadis.2017.10.010
PMCID:
PMC5705342
AbstractArticlePDF–1.1M
6.
Sphingolipid signaling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1
Rita Vilaça, Elísio Silva, André Nadais, Vítor Teixeira, Nabil Matmati, Joana Gaifem, Yusuf A. Hannun, Maria Clara Sá Miranda, Vítor Costa
Mol Microbiol. Author manuscript; available in PMC 2015 Feb 1.
Published in final edited form as: Mol Microbiol. 2014 Feb; 91(3): 438–451. Published online 2013 Dec 12. doi: 10.1111/mmi.12470
PMCID:
PMC3954977
AbstractArticlePDF–2.5M
7.
Unbiased yeast screens identify cellular pathways affected in Niemann–Pick disease type C
Alexandria Colaco, María E Fernández-Suárez, Dawn Shepherd, Lihi Gal, Chen Bibi, Silvia Chuartzman, Alan Diot, Karl Morten, Emily Eden, Forbes D Porter, Joanna Poulton, Nick Platt, Maya Schuldiner, Frances M Platt
Life Sci Alliance. 2020 Jul; 3(7): e201800253. Published online 2020 Jun 2. doi: 10.26508/lsa.201800253
PMCID:
PMC7283134
AbstractArticlePDF–1.8M
8.
Identification and characterization of protein interactions with the major Niemann–Pick type C disease protein in yeast reveals pathways of therapeutic potential
Natalie Hammond, Jamie Snider, Igor Stagljar, Kevin Mitchell, Kirill Lagutin, Matthew Jessulat, Mohan Babu, Paul H Teesdale-Spittle, Jeffrey P Sheridan, Stephen L Sturley, Andrew B Munkacsi
Genetics. 2023 Sep; 225(1): iyad129. Published online 2023 Jul 13. doi: 10.1093/genetics/iyad129
PMCID:
PMC10471228
AbstractArticlePDF–32M
9.
Direct imaging reveals stable, micrometer-scale lipid domains that segregate proteins in live cells
Alexandre Toulmay, William A. Prinz
J Cell Biol. 2013 Jul 8; 202(1): 35–44. doi: 10.1083/jcb.201301039
PMCID:
PMC3704982
AbstractArticlePDF–2.5M
10.
Molecular mechanisms underlying genotype-dependent responses to dietary restriction
Jennifer Schleit, Simon C. Johnson, Christopher F. Bennett, Marissa Simko, Natalie Trongtham, Anthony Castanza, Edward J. Hsieh, Richard M. Moller, Brian M. Wasko, Joe R. Delaney, George L. Sutphin, Daniel Carr, Christopher J. Murakami, Autumn Tocchi, Bo Xian, Weiyang Chen, Tao Yu, Sarani Goswami, Sean Higgins, Mollie Holmberg, Ki-Soo Jeong, Jin R. Kim, Shannon Klum, Eric Liao, Michael S. Lin, Winston Lo, Hillary Miller, Brady Olsen, Zhao J. Peng, Tom Pollard, Prarthana Pradeep, Dillon Pruett, Dilreet Rai, Vanessa Ros, Minnie Singh, Benjamin L. Spector, Helen Vander Wende, Elroy H. An, Marissa Fletcher, Monika Jelic, Peter S. Rabinovitch, Michael J. MacCoss, Jing-Dong J. Han, Brian K. Kennedy, Matt Kaeberlein
Aging Cell. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Aging Cell. 2013 Dec; 12(6): 10.1111/acel.12130. Published online 2013 Aug 11. doi: 10.1111/acel.12130
PMCID:
PMC3838465
AbstractArticlePDF–2.3M
11.
Mapping the functional yeast ABC transporter interactome
Jamie Snider, Asad Hanif, Mid Eum Lee, Ke Jin, Analyn R. Yu, Chris Graham, Matthew Chuk, Dunja Damjanovic, Marta Wierzbicka, Priscilla Tang, Dina Balderes, Victoria Wong, Matthew Jessulat, Katelyn D. Darowski, Bryan-Joseph San Luis, Igor Shevelev, Stephen L Sturley, Charles Boone, Jack F. Greenblatt, Zhaolei Zhang, Christian M. Paumi, Mohan Babu, Hay-Oak Park, Susan Michaelis, Igor Stagljar
Nat Chem Biol. Author manuscript; available in PMC 2014 Mar 1.
Published in final edited form as: Nat Chem Biol. 2013 Sep; 9(9): 565–572. Published online 2013 Jul 7. doi: 10.1038/nchembio.1293
PMCID:
PMC3835492
AbstractArticlePDF–1.2M
12.
Heterozygous Yeast Deletion Collection Screens Reveal Essential Targets of Hsp90
Eric A. Franzosa, Véronique Albanèse, Judith Frydman, Yu Xia, Amie J. McClellan
PLoS One. 2011; 6(11): e28211. Published online 2011 Nov 30. doi: 10.1371/journal.pone.0028211
PMCID:
PMC3227642
AbstractArticlePDF–1.7M
13.
Whi3, a Developmental Regulator of Budding Yeast, Binds a Large Set of mRNAs Functionally Related to the Endoplasmic Reticulum
Neus Colomina, Francisco Ferrezuelo, Hongyin Wang, Martí Aldea, Eloi Garí
J Biol Chem. 2008 Oct 17; 283(42): 28670–28679. doi: 10.1074/jbc.M804604200
PMCID:
PMC2661415
AbstractArticlePDF–680K
14.
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking
Pablo S Aguilar, Florian Fröhlich, Michael Rehman, Mike Shales, Igor Ulitsky, Agustina Olivera-Couto, Hannes Braberg, Ron Shamir, Peter Walter, Matthias Mann, Christer S Ejsing, Nevan J Krogan, Tobias C Walther
Nat Struct Mol Biol. Author manuscript; available in PMC 2011 Jul 1.
Published in final edited form as: Nat Struct Mol Biol. 2010 Jul; 17(7): 901–908. Published online 2010 Jun 6. doi: 10.1038/nsmb.1829
PMCID:
PMC3073498
AbstractArticlePDF–1.9M
15.
Evolution of Phosphoregulation: Comparison of Phosphorylation Patterns across Yeast Species
Pedro Beltrao, Jonathan C. Trinidad, Dorothea Fiedler, Assen Roguev, Wendell A. Lim, Kevan M. Shokat, Alma L. Burlingame, Nevan J. Krogan
PLoS Biol. 2009 Jun; 7(6): e1000134. Published online 2009 Jun 23. doi: 10.1371/journal.pbio.1000134
Correction in:
PLoS Biol. 2009 Nov; 7(11): 10.1371/annotation/66479889-5e57-4213-bf25-c4e8cf3d933b.
PMCID:
PMC2691599
AbstractArticlePDF–659K
16.
Dissecting DNA damage response pathways by analyzing protein localization and abundance changes during DNA replication stress
Johnny M. Tkach, Askar Yimit, Anna Y. Lee, Michael Riffle, Michael Costanzo, Daniel Jaschob, Jason A. Hendry, Jiongwen Ou, Jason Moffat, Charles Boone, Trisha N. Davis, Corey Nislow, Grant W. Brown
Nat Cell Biol. Author manuscript; available in PMC 2013 Mar 1.
Published in final edited form as: Nat Cell Biol. 2012 Sep; 14(9): 966–976. Published online 2012 Jul 29. doi: 10.1038/ncb2549
PMCID:
PMC3434236
AbstractArticlePDF–1.5M
17.
Target selection by natural and redesigned PUF proteins
Douglas F. Porter, Yvonne Y. Koh, Brett VanVeller, Ronald T. Raines, Marvin Wickens
Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52): 15868–15873. Published online 2015 Dec 14. doi: 10.1073/pnas.1508501112
PMCID:
PMC4703012
AbstractArticlePDF–1.3M
18.
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria
Suzanne Hoppins, Sean R. Collins, Ann Cassidy-Stone, Eric Hummel, Rachel M. DeVay, Laura L. Lackner, Benedikt Westermann, Maya Schuldiner, Jonathan S. Weissman, Jodi Nunnari
J Cell Biol. 2011 Oct 17; 195(2): 323–340. doi: 10.1083/jcb.201107053
PMCID:
PMC3198156
AbstractArticlePDF–4.1M
19.
One library to make them all: Streamlining yeast library creation by a SWAp-Tag (SWAT) strategy
Ido Yofe, Uri Weill, Matthias Meurer, Silvia Chuartzman, Einat Zalckvar, Omer Goldman, Shifra Ben-Dor, Conny Schütze, Nils Wiedemann, Michael Knop, Anton Khmelinskii, Maya Schuldiner
Nat Methods. Author manuscript; available in PMC 2016 Sep 22.
Published in final edited form as: Nat Methods. 2016 Apr; 13(4): 371–378. Published online 2016 Feb 29. doi: 10.1038/nmeth.3795
PMCID:
PMC4869835
AbstractArticlePDF–2.7M
20.
A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast
Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger
G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296
PMCID:
PMC9836348
AbstractArticlePDF–857K

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