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Select item 37897911.

The C-terminal Residues of Saccharomyces cerevisiae Mec1 Are Required for Its Localization, Stability, and Function

Lance F. DaSilva, Samantha Pillon, Julie Genereaux, Megan J. Davey, Gregory B. Gloor, Jim Karagiannis, Christopher J. Brandl

G3 (Bethesda) 2013 Oct; 3(10): 1661–1674. Published online 2013 Oct 1. doi: 10.1534/g3.113.006841

PMCID:: PMC3789791

Abstract Article PDF–2.1M

Select item 3196992.

The PAM domain, a multi-protein complex-associated module with an all-alpha-helix fold

Francesca D Ciccarelli, Elisa Izaurralde, Peer Bork

BMC Bioinformatics. 2003; 4: 64. Published online 2003 Dec 19. doi: 10.1186/1471-2105-4-64

PMCID:: PMC319699

Abstract Article PDF–349K

Select item 2760683.

Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1.

K Kominami, N Okura, M Kawamura, G N DeMartino, C A Slaughter, N Shimbara, C H Chung, M Fujimuro, H Yokosawa, Y Shimizu, N Tanahashi, K Tanaka, A Toh-e

Mol Biol Cell. 1997 Jan; 8(1): 171–187. doi: 10.1091/mbc.8.1.171

PMCID:: PMC276068

Summary Page Browse PDF–4.4M

Select item 11708204.

Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome.

D M Rubin, M H Glickman, C N Larsen, S Dhruvakumar, D Finley

EMBO J. 1998 Sep 1; 17(17): 4909–4919. doi: 10.1093/emboj/17.17.4909

PMCID:: PMC1170820

Summary PDF–330K

Select item 1656195.

The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome

Jun Imai, Mikako Maruya, Hideki Yashiroda, Ichiro Yahara, Keiji Tanaka

EMBO J. 2003 Jul 15; 22(14): 3557–3567. doi: 10.1093/emboj/cdg349

PMCID:: PMC165619

Abstract Article PDF–482K

Select item 3169436.

Cyclin-dependent kinase and Cks/Suc1 interact with the proteasome in yeast to control proteolysis of M-phase targets

Peter Kaiser, Vincent Moncollin, Duncan J. Clarke, Mark H. Watson, Bonnie L. Bertolaet, Steven I. Reed, Eric Bailly

Genes Dev. 1999 May 1; 13(9): 1190–1202. doi: 10.1101/gad.13.9.1190

PMCID:: PMC316943

Abstract Article PDF–532K

Select item 846837.

Functional Characterization of Rpn3 Uncovers a Distinct 19S Proteasomal Subunit Requirement for Ubiquitin-Dependent Proteolysis of Cell Cycle Regulatory Proteins in Budding Yeast

Eric Bailly, Steven I. Reed

Mol Cell Biol. 1999 Oct; 19(10): 6872–6890. doi: 10.1128/mcb.19.10.6872

PMCID:: PMC84683

Abstract Article PDF–4.7M

Select item 47495698.

Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition

Corey M Dambacher, Evan J Worden, Mark A Herzik, Jr., Andreas Martin, Gabriel C Lander

eLife. 2016; 5: e13027. Published online 2016 Jan 8. doi: 10.7554/eLife.13027

PMCID:: PMC4749569

Abstract Article PDF–2.8M

Select item 46010819.

A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly

Robert J. Tomko, Jr., David W. Taylor, Zhuo A. Chen, Hong-Wei Wang, Juri Rappsilber, Mark Hochstrasser

Cell. 2015 Oct 8; 163(2): 432–444. doi: 10.1016/j.cell.2015.09.022

PMCID:: PMC4601081

Abstract Article PDF–4.0M

Select item 394755410.

The Intrinsically Disordered Sem1 Protein Functions as a Molecular Tether During Proteasome Lid Biogenesis

Robert J. Tomko, Jr., Mark Hochstrasser

Mol Cell. Author manuscript; available in PMC 2015 Feb 6.

Published in final edited form as: Mol Cell. 2014 Feb 6; 53(3): 433–443. Published online 2014 Jan 9. doi: 10.1016/j.molcel.2013.12.009

PMCID:: PMC3947554

Abstract Article PDF–5.8M

Select item 376348611.

A Proteasome Assembly Defect in rpn3 Mutants Is Associated with Rpn11 Instability and Increased Sensitivity to Stress

Kishore Kumar Joshi, Li Chen, Nidza Torres, Vincent Tournier, Kiran Madura

J Mol Biol. Author manuscript; available in PMC 2013 Sep 5.

Published in final edited form as: J Mol Biol. 2011 Jul 15; 410(3): 383–399. Published online 2011 May 18. doi: 10.1016/j.jmb.2011.05.005

PMCID:: PMC3763486

Abstract Article PDF–982K

Select item 152323012.

Structural Organization of the 19S Proteasome Lid: Insights from MS of Intact Complexes

Michal Sharon, Thomas Taverner, Xavier I Ambroggio, Raymond J Deshaies, Carol V Robinson

PLoS Biol. 2006 Aug; 4(8): e267. Published online 2006 Aug 1. doi: 10.1371/journal.pbio.0040267

PMCID:: PMC1523230

Abstract Article PDF–1.1M

Select item 441249913.

The Protein Quality Control Machinery Regulates Its Misassembled Proteasome Subunits

Lee Zeev Peters, Ofri Karmon, Galit David-Kadoch, Rotem Hazan, Tzenlin Yu, Michael H. Glickman, Shay Ben-Aroya

PLoS Genet. 2015 Apr; 11(4): e1005178. Published online 2015 Apr 28. doi: 10.1371/journal.pgen.1005178

PMCID:: PMC4412499

Abstract Article PDF–2.0M

Select item 325151514.

Incorporation of the Rpn12 Subunit Couples Completion of Proteasome Regulatory Particle Lid Assembly to Lid-Base Joining

Robert J. Tomko, Jr., Mark Hochstrasser

Mol Cell. Author manuscript; available in PMC 2012 Dec 23.

Published in final edited form as: Mol Cell. 2011 Dec 23; 44(6): 907–917. doi: 10.1016/j.molcel.2011.11.020

PMCID:: PMC3251515

Abstract Article PDF–4.9M

Select item 455190315.

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

Peter Tsvetkov, Marc L Mendillo, Jinghui Zhao, Jan E Carette, Parker H Merrill, Domagoj Cikes, Malini Varadarajan, Ferdy R van Diemen, Josef M Penninger, Alfred L Goldberg, Thijn R Brummelkamp, Sandro Santagata, Susan Lindquist

eLife. 2015; 4: e08467. Published online 2015 Sep 1. doi: 10.7554/eLife.08467

PMCID:: PMC4551903

Abstract Article PDF–3.3M

Select item 264616016.

Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome

Yasushi Saeki, Tai Kudo, Takayuki Sone, Yoshiko Kikuchi, Hideyoshi Yokosawa, Akio Toh-e, Keiji Tanaka

EMBO J. 2009 Feb 18; 28(4): 359–371. Published online 2009 Jan 15. doi: 10.1038/emboj.2008.305

PMCID:: PMC2646160

Abstract Article PDF–462K

Select item 691082917.

Specific lid-base contacts in the 26s proteasome control the conformational switching required for substrate degradation

Eric R Greene, Ellen A Goodall, Andres H de la Peña, Mary E Matyskiela, Gabriel C Lander, Andreas Martin

eLife. 2019; 8: e49806. Published online 2019 Nov 28. doi: 10.7554/eLife.49806

PMCID:: PMC6910829

Abstract Article PDF–1.6M

Select item 533983318.

High-resolution cryo-EM structure of the proteasome in complex with ADP-AlFx

Zhanyu Ding, Zhenglin Fu, Cong Xu, Yifan Wang, Yanxing Wang, Junrui Li, Liangliang Kong, Jinhuan Chen, Na Li, Rongguang Zhang, Yao Cong

Cell Res. 2017 Mar; 27(3): 373–385. Published online 2017 Jan 20. doi: 10.1038/cr.2017.12

PMCID:: PMC5339833

Abstract Article PDF–2.7M

Select item 450720619.

Structural characterization of the interaction of Ubp6 with the 26S proteasome

Antje Aufderheide, Florian Beck, Florian Stengel, Michaela Hartwig, Andreas Schweitzer, Günter Pfeifer, Alfred L. Goldberg, Eri Sakata, Wolfgang Baumeister, Friedrich Förster

Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28): 8626–8631. Published online 2015 Jun 30. doi: 10.1073/pnas.1510449112