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Select item 88078741.

Recruitment of Scc2/4 to double-strand breaks depends on γH2A and DNA end resection

Martin Scherzer, Fosco Giordano, Maria Solé Ferran, Lena Ström

Life Sci Alliance. 2022 May; 5(5): e202101244. Published online 2022 Jan 27. doi: 10.26508/lsa.202101244

PMCID:: PMC8807874

Abstract Article PDF–2.0M

Select item 62056312.

Topological in vitro loading of the budding yeast cohesin ring onto DNA

Masashi Minamino, Torahiko L Higashi, Céline Bouchoux, Frank Uhlmann

Life Sci Alliance. 2018 Oct; 1(5): e201800143. Published online 2018 Oct 26. doi: 10.26508/lsa.201800143

PMCID:: PMC6205631

Abstract Article PDF–1.3M

Select item 44719373.

Structural evidence for Scc4-dependent localization of cohesin loading

Stephen M Hinshaw, Vasso Makrantoni, Alastair Kerr, Adèle L Marston, Stephen C Harrison

eLife. 2015; 4: e06057. Published online 2015 Jun 3. doi: 10.7554/eLife.06057

PMCID:: PMC4471937

Abstract Article PDF–3.0M

Select item 40249034.

Cell cycle-specific cleavage of Scc2 regulates its cohesin deposition activity

Julie Woodman, Tyler Fara, Monika Dzieciatkowska, Michael Trejo, Nancy Luong, Kirk C. Hansen, Paul C. Megee

Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 7060–7065. Published online 2014 Apr 28. doi: 10.1073/pnas.1321722111

PMCID:: PMC4024903

Abstract Article PDF–970K

Select item 49789185.

Identification of Functional Domains in the Cohesin Loader Subunit Scc4 by a Random Insertion/Dominant Negative Screen

Michal Shwartz, Avi Matityahu, Itay Onn

G3 (Bethesda) 2016 Aug; 6(8): 2655–2663. Published online 2016 Jun 7. doi: 10.1534/g3.116.031674

PMCID:: PMC4978918

Abstract Article PDF–1.4M

Select item 46260616.

Phosphorylation of the Scc2 cohesin deposition complex subunit regulates chromosome condensation through cohesin integrity

Julie Woodman, Matthew Hoffman, Monika Dzieciatkowska, Kirk C. Hansen, Paul C. Megee

Mol Biol Cell. 2015 Nov 1; 26(21): 3754–3767. doi: 10.1091/mbc.E15-03-0165

PMCID:: PMC4626061

Abstract Article PDF–3.5M

Select item 27587387.

The Scc2/Scc4 cohesin loader determines the distribution of cohesin on budding yeast chromosomes

Igor Kogut, Jianbin Wang, Vincent Guacci, Rohinton K. Mistry, Paul C. Megee

Genes Dev. 2009 Oct 1; 23(19): 2345–2357. doi: 10.1101/gad.1819409

PMCID:: PMC2758738

Abstract Article PDF–751K

Select item 41772328.

The Scc2/Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions

Lidia Lopez-Serra, Gavin Kelly, Harshil Patel, Aengus Stewart, Frank Uhlmann

Nat Genet. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Nat Genet. 2014 Oct; 46(10): 1147–1151. Published online 2014 Aug 31. doi: 10.1038/ng.3080

PMCID:: PMC4177232

Abstract Article PDF–1.4M

Select item 26103589.

Cohesin relocation from sites of chromosomal loading to places of convergent transcription

Armelle Lengronne, Yuki Katou, Shihori Yokobayashi, Saori Mori, Gavin Kelly, Takehiko Itoh, Yoshinori Watanabe, Katsuhiko Shirahige, Frank Uhlmann

Nature. Author manuscript; available in PMC 2008 Dec 27.

Published in final edited form as: Nature. 2004 Jul 29; 430(6999): 573–578. Published online 2004 Jun 30. doi: 10.1038/nature02742

PMCID:: PMC2610358

Abstract Article PDF–1.3M

Select item 1015346010.

A model for Scc2p stimulation of cohesin's ATPase and its inhibition by acetylation of Smc3p

Kevin Boardman, Siheng Xiang, Fiona Chatterjee, Udochi Mbonu, Vincent Guacci, Douglas Koshland

Genes Dev. 2023 Apr 1; 37(7-8): 277–290. doi: 10.1101/gad.350278.122

PMCID:: PMC10153460

Abstract Article PDF–4.4M

Select item 476354411.

ATP Hydrolysis Is Required for Relocating Cohesin from Sites Occupied by Its Scc2/4 Loading Complex

Bin Hu, Takehiko Itoh, Ajay Mishra, Yuki Katoh, Kok-Lung Chan, William Upcher, Camilla Godlee, Maurici B. Roig, Katsuhiko Shirahige, Kim Nasmyth

Curr Biol. Author manuscript; available in PMC 2016 Feb 23.

Published in final edited form as: Curr Biol. 2011 Jan 11; 21(1): 12–24. Published online 2010 Dec 23. doi: 10.1016/j.cub.2010.12.004

PMCID:: PMC4763544

Abstract Article PDF–2.5M

Select item 561017512.

The Kinetochore Receptor for the Cohesin Loading Complex

Stephen M. Hinshaw, Vasso Makrantoni, Stephen C. Harrison, Adèle L. Marston

Cell. 2017 Sep 21; 171(1): 72–84.e13. doi: 10.1016/j.cell.2017.08.017

PMCID:: PMC5610175

Abstract Article PDF–5.4M

Select item 492993213.

Evidence for cohesin sliding along budding yeast chromosomes

Maria Ocampo-Hafalla, Sofía Muñoz, Catarina P. Samora, Frank Uhlmann

Open Biol. 2016 Jun; 6(6): 150178. Published online 2016 Jun 8. doi: 10.1098/rsob.150178

PMCID:: PMC4929932

Abstract Article PDF–1.5M

Select item 827976114.

Folding of cohesin’s coiled coil is important for Scc2/4-induced association with chromosomes

Naomi J Petela, Andres Gonzalez Llamazares, Sarah Dixon, Bin Hu, Byung-Gil Lee, Jean Metson, Heekyo Seo, Antonio Ferrer-Harding, Menelaos Voulgaris, Thomas Gligoris, James Collier, Byung-Ha Oh, Jan Löwe, Kim A Nasmyth

eLife. 2021; 10: e67268. Published online 2021 Jul 14. doi: 10.7554/eLife.67268

PMCID:: PMC8279761

Abstract Article PDF–7.6M

Select item 753684315.

A dCas9-Based System Identifies a Central Role for Ctf19 in Kinetochore-Derived Suppression of Meiotic Recombination

Lisa-Marie Kuhl, Vasso Makrantoni, Sarah Recknagel, Animish N. Vaze, Adele L. Marston, Gerben Vader

Genetics. 2020 Oct; 216(2): 395–408. Published online 2020 Aug 25. doi: 10.1534/genetics.120.303384

PMCID:: PMC7536843

Abstract Article PDF–1.7M

Select item 602891916.

Scc2 Is a Potent Activator of Cohesin’s ATPase that Promotes Loading by Binding Scc1 without Pds5

Naomi J. Petela, Thomas G. Gligoris, Jean Metson, Byung-Gil Lee, Menelaos Voulgaris, Bin Hu, Sotaro Kikuchi, Christophe Chapard, Wentao Chen, Eeson Rajendra, Madhusudhan Srinivisan, Hongtao Yu, Jan Löwe, Kim A. Nasmyth

Mol Cell. 2018 Jun 21; 70(6): 1134–1148.e7. doi: 10.1016/j.molcel.2018.05.022

PMCID:: PMC6028919

Abstract Article PDF–6.9M

Select item 435204417.

A Conserved Domain in the Scc3 Subunit of Cohesin Mediates the Interaction with Both Mcd1 and the Cohesin Loader Complex

Ola Orgil, Avi Matityahu, Thomas Eng, Vincent Guacci, Douglas Koshland, Itay Onn

PLoS Genet. 2015 Mar; 11(3): e1005036. Published online 2015 Mar 6. doi: 10.1371/journal.pgen.1005036

PMCID:: PMC4352044

Abstract Article PDF–3.2M

Select item 251881118.

Identification of cis-acting sites for condensin loading onto budding yeast chromosomes

Claudio D’Ambrosio, Christine Katrin Schmidt, Yuki Katou, Gavin Kelly, Takehiko Itoh, Katsuhiko Shirahige, Frank Uhlmann

Genes Dev. 2008 Aug 15; 22(16): 2215–2227. doi: 10.1101/gad.1675708

PMCID:: PMC2518811

Abstract Article PDF–1.0M

Select item 267650719.

The Elg1 Clamp Loader Plays a Role in Sister Chromatid Cohesion

Oren Parnas, Adi Zipin-Roitman, Yuval Mazor, Batia Liefshitz, Shay Ben-Aroya, Martin Kupiec

PLoS One. 2009; 4(5): e5497. Published online 2009 May 11. doi: 10.1371/journal.pone.0005497

PMCID:: PMC2676507

Abstract Article PDF–576K

Select item 688117120.

A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules

Pilar Gutierrez-Escribano, Matthew D. Newton, Aida Llauró, Jonas Huber, Loredana Tanasie, Joseph Davy, Isabel Aly, Ricardo Aramayo, Alex Montoya, Holger Kramer, Johannes Stigler, David S. Rueda, Luis Aragon

Sci Adv. 2019 Nov; 5(11): eaay6804. Published online 2019 Nov 27. doi: 10.1126/sciadv.aay6804