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Items: 1 to 20 of 44

1.
Spondyloepimetaphyseal dysplasia with elevated plasma lysosomal enzymes caused by homozygous variant in MBTPS1
Daniel R. Carvalho, Carlos E. Speck-Martins, Jaime M. Brum, Carlos R. Ferreira, Nara L. M. Sobreira
Am J Med Genet A. Author manuscript; available in PMC 2021 May 20.
Published in final edited form as: Am J Med Genet A. 2020 Jul; 182(7): 1796–1800. Published online 2020 May 18. doi: 10.1002/ajmg.a.61614
PMCID:
PMC8136467
AbstractArticlePDF–499K
2.
Site-1 protease function is essential for the generation of antibody secreting cells and reprogramming for secretory activity
Muna Al-Maskari, Matthew A. Care, Emily Robinson, Mario Cocco, Reuben M. Tooze, Gina M. Doody
Sci Rep. 2018; 8: 14338. Published online 2018 Sep 25. doi: 10.1038/s41598-018-32705-7
PMCID:
PMC6156501
AbstractArticlePDF–2.7M
3.
Zymogen Activation and Subcellular Activity of Subtilisin Kexin Isozyme 1/Site 1 Protease
Joel Ramos da Palma, Dominique Julien Burri, Joël Oppliger, Marco Salamina, Laura Cendron, Patrizia Polverino de Laureto, Nabil Georges Seidah, Stefan Kunz, Antonella Pasquato
J Biol Chem. 2014 Dec 26; 289(52): 35743–35756. Published online 2014 Nov 5. doi: 10.1074/jbc.M114.588525
PMCID:
PMC4276844
AbstractArticlePDF–2.5M
4.
Differential Recognition of Old World and New World Arenavirus Envelope Glycoproteins by Subtilisin Kexin Isozyme 1 (SKI-1)/Site 1 Protease (S1P)
Dominique J. Burri, Joel Ramos da Palma, Nabil G. Seidah, Giuseppe Zanotti, Laura Cendron, Antonella Pasquato, Stefan Kunz
J Virol. 2013 Jun; 87(11): 6406–6414. doi: 10.1128/JVI.00072-13
PMCID:
PMC3648084
AbstractArticlePDF–1.2M
5.
Site 1 Protease Is Required for Proteolytic Processing of the Glycoproteins of the South American Hemorrhagic Fever Viruses Junin, Machupo, and Guanarito
Jillian M. Rojek, Andrew M. Lee, NgocThao Nguyen, Christina F. Spiropoulou, Stefan Kunz
J Virol. 2008 Jun; 82(12): 6045–6051. Published online 2008 Apr 9. doi: 10.1128/JVI.02392-07
PMCID:
PMC2395157
AbstractArticlePDF–705K
6.
Crimean-Congo Hemorrhagic Fever Virus Glycoprotein Processing by the Endoprotease SKI-1/S1P Is Critical for Virus Infectivity
Éric Bergeron, Martin J. Vincent, Stuart T. Nichol
J Virol. 2007 Dec; 81(23): 13271–13276. Published online 2007 Sep 26. doi: 10.1128/JVI.01647-07
PMCID:
PMC2169102
AbstractArticlePDF–404K
7.
The Inhibition of the Membrane-Bound Transcription Factor Site-1 Protease (MBTP1) Alleviates the p.Phe508del-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Defects in Cystic Fibrosis Cells
Raphaël Santinelli, Nathalie Benz, Julie Guellec, Fabien Quinquis, Ervin Kocas, Johan Thomas, Tristan Montier, Chandran Ka, Emilie Luczka-Majérus, Edouard Sage, Claude Férec, Christelle Coraux, Pascal Trouvé
Cells. 2024 Jan; 13(2): 185. Published online 2024 Jan 18. doi: 10.3390/cells13020185
PMCID:
PMC10814821
AbstractArticlePDF–3.6M
8.
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis
Chao Fang, Pan Ren, Ganlan Bian, Jian Wang, Jiaxin Bai, Jiaxing Huang, Yixiao Ding, Xueyong Li, Mingkai Li, Zheng Hou
EMBO Rep. 2023 Aug; 24(8): e56635. Published online 2023 Jun 26. doi: 10.15252/embr.202256635
PMCID:
PMC10398662
AbstractArticlePDF–3.1M
9.
Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking
Yuji Kondo, Jianxin Fu, Hua Wang, Christopher Hoover, J. Michael McDaniel, Richard Steet, Debabrata Patra, Jianhua Song, Laura Pollard, Sara Cathey, Tadayuki Yago, Graham Wiley, Susan Macwana, Joel Guthridge, Samuel McGee, Shibo Li, Courtney Griffin, Koichi Furukawa, Judith A. James, Changgeng Ruan, Rodger P. McEver, Klaas J. Wierenga, Patrick M. Gaffney, Lijun Xia
JCI Insight. 2018 Jul 26; 3(14): e121596. Published online 2018 Jul 26. doi: 10.1172/jci.insight.121596
PMCID:
PMC6124414
AbstractArticlePDF–9.5M
10.
Mechanism of Folding and Activation of Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P)
Joel Ramos da Palma, Laura Cendron, Nabil Georges Seidah, Antonella Pasquato, Stefan Kunz
J Biol Chem. 2016 Jan 29; 291(5): 2055–2066. Published online 2015 Dec 8. doi: 10.1074/jbc.M115.677757
PMCID:
PMC4732194
AbstractArticlePDF–2.3M
11.
Site-1 protease-activated formation of lysosomal targeting motifs is independent of the lipogenic transcription control
Sarah Klünder, Jörg Heeren, Sandra Markmann, René Santer, Thomas Braulke, Sandra Pohl
J Lipid Res. 2015 Aug; 56(8): 1625–1632. doi: 10.1194/jlr.M060756
PMCID:
PMC4514003
AbstractArticlePDF–908K
12.
The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation
Jian Hao, Yi-Min Huang, Ming-Hui Zhao, Min Chen
Arthritis Res Ther. 2014; 16(4): R142. Published online 2014 Jul 7. doi: 10.1186/ar4604
PMCID:
PMC4227110
AbstractArticlePDF–991K
13.
High-density lipoprotein of patients with Type 2 Diabetes Mellitus upregulates cyclooxgenase-2 expression and prostacyclin I-2 release in endothelial cells: relationship with HDL-associated sphingosine-1-phosphate
Xunliang Tong, Hui Peng, Donghui Liu, Liang Ji, Chenguang Niu, Jun Ren, Bing Pan, Jianying Hu, Lemin Zheng, Yining Huang
Cardiovasc Diabetol. 2013; 12: 27. Published online 2013 Jan 30. doi: 10.1186/1475-2840-12-27
PMCID:
PMC3599898
AbstractArticlePDF–737K
14.
Targeting SPHK1/S1PR3-regulated S-1-P metabolic disorder triggers autophagic cell death in pulmonary lymphangiomyomatosis (LAM)
Fei Li, Yifan Zhang, Zhoujun Lin, Lizhong Yan, Qiao Liu, Yin Li, Xiaolin Pei, Ya Feng, Xiao Han, Juan Yang, Fangxu Zheng, Tianjiao Li, Yupeng Zhang, Zhenkun Fu, Di Shao, Jane Yu, Chenggang Li
Cell Death Dis. 2022 Dec; 13(12): 1065. Published online 2022 Dec 21. doi: 10.1038/s41419-022-05511-3
PMCID:
PMC9772321
AbstractArticlePDF–6.2M
15.
Genetics of the human face: Identification of large-effect single gene variants
Daniel J. M. Crouch, Bruce Winney, Willem P. Koppen, William J. Christmas, Katarzyna Hutnik, Tammy Day, Devendra Meena, Abdelhamid Boumertit, Pirro Hysi, Ayrun Nessa, Tim D. Spector, Josef Kittler, Walter F. Bodmer
Proc Natl Acad Sci U S A. 2018 Jan 23; 115(4): E676–E685. Published online 2018 Jan 4. doi: 10.1073/pnas.1708207114
PMCID:
PMC5789906
AbstractArticlePDF–1.4M
16.
Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast–osteoblast coupling
Jiyoon Ryu, Hyung Joon Kim, Eun-Ju Chang, Hao Huang, Yoshiko Banno, Hong-Hee Kim
EMBO J. 2006 Dec 13; 25(24): 5840–5851. Published online 2006 Nov 23. doi: 10.1038/sj.emboj.7601430
PMCID:
PMC1698879
AbstractArticlePDF–633K
17.
Proteolytic processing of secretory pathway kinase Fam20C by site-1 protease promotes biomineralization
Xinxin Chen, Jianchao Zhang, Pulan Liu, Yangyang Wei, Xi’e Wang, Junyu Xiao, Chih-chen Wang, Lei Wang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2100133118. Published online 2021 Aug 4. doi: 10.1073/pnas.2100133118
PMCID:
PMC8364200
AbstractArticlePDF–2.5M
18.
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization
Nabil G. Seidah, Seyed J. Mowla, Josée Hamelin, Aida M. Mamarbachi, Suzanne Benjannet, Barry B. Touré, Ajoy Basak, Jon Scott Munzer, Jadwiga Marcinkiewicz, Mei Zhong, Jean-Christophe Barale, Claude Lazure, Richard A. Murphy, Michel Chrétien, Mieczyslaw Marcinkiewicz
Proc Natl Acad Sci U S A. 1999 Feb 16; 96(4): 1321–1326. doi: 10.1073/pnas.96.4.1321
PMCID:
PMC15461
AbstractArticlePDF–322K
19.
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis
Xin Tracy Liu, Yu Huang, Da Liu, Yingxin Celia Jiang, Min Zhao, Long Hoa Chung, Xingxing Daisy Han, Yinan Zhao, Jinbiao Chen, Paul Coleman, Ka Ka Ting, Collin Tran, Yingying Su, Claude Vincent Dennis, Atul Bhatnagar, Ken Liu, Anthony Simon Don, Mathew Alexander Vadas, Mark Douglas Gorrell, Shubiao Zhang, Michael Murray, Mary Meltem Kavurma, Geoffrey William McCaughan, Jennifer Ruth Gamble, Yanfei Qi
J Transl Med. 2024; 22: 43. Published online 2024 Jan 10. doi: 10.1186/s12967-023-04830-z
PMCID:
PMC10782643
AbstractArticlePDF–7.3M
20.
Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
Nitai C. Hait, Jeremy Allegood, Michael Maceyka, Graham M. Strub, Kuzhuvelil B. Harikumar, Sandeep K. Singh, Cheng Luo, Ronen Marmorstein, Tomasz Kordula, Sheldon Milstien, Sarah Spiegel
Science. Author manuscript; available in PMC 2010 Apr 7.
Published in final edited form as: Science. 2009 Sep 4; 325(5945): 1254–1257. doi: 10.1126/science.1176709
Correction in:
volume 326 on page 366
PMCID:
PMC2850596
AbstractArticlePDF–1.5M

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