PMC Links for Gene (Select 8879) - PMC

Andreas R Janecke, Ruijuan Xu, Elisabeth Steichen-Gersdorf, Siegfried Waldegger, Andreas Entenmann, Thomas Giner, Iris Krainer, Lukas A Huber, Michael W Hess, Yaacov Frishberg, Hila Barash, Shay Tzur, Nira Schreyer-Shafir, Rivka Sukenik–Halevy, Tania Zehavi, Annick Raas-Rothschild, Cungui Mao, Thomas Müller

Hum Mutat. Author manuscript; available in PMC 2018 Apr 1.

Published in final edited form as: Hum Mutat. 2017 Apr; 38(4): 365–372. Published online 2017 Mar 6. doi: 10.1002/humu.23192

PMCID:: PMC5384969

Abstract Article PDF–1.0M

Select item 91282394.

Nuclear Sphingosine-1-phosphate Lyase Generated Δ2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

David L. Ebenezer, Ramaswamy Ramchandran, Panfeng Fu, Lizar A. Mangio, Vidyani Suryadevara, Alison W. Ha, Evgeny Berdyshev, Paul P. Van Veldhoven, Stephen J. Kron, Fabian Schumacher, Burkhard Kleuser, Viswanathan Natarajan

Cell Biochem Biophys. Author manuscript; available in PMC 2022 May 24.

Published in final edited form as: Cell Biochem Biophys. 2021 Sep; 79(3): 575–592. Published online 2021 Jun 3. doi: 10.1007/s12013-021-01005-9

PMCID:: PMC9128239

Abstract Article PDF–1.6M

Select item 81098485.

Influenza A virus NS1 induces degradation of sphingosine 1-phosphate lyase to obstruct the host innate immune response

Jennifer J. Wolf, Chuan Xia, Caleb J. Studstill, Hanh Ngo, Steven L. Brody, Paul E. Anderson, Bumsuk Hahm

Virology. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Virology. 2021 Jun; 558: 67–75. Published online 2021 Mar 13. doi: 10.1016/j.virol.2021.02.006

PMCID:: PMC8109848

Abstract Article PDF–1.2M

Select item 73500296.

Heterogenous Nuclear Ribonucleoprotein H1 Promotes Colorectal Cancer Progression through the Stabilization of mRNA of Sphingosine-1-Phosphate Lyase 1

Keitaro Takahashi, Mikihiro Fujiya, Hiroaki Konishi, Yuki Murakami, Takuya Iwama, Takahiro Sasaki, Takehito Kunogi, Aki Sakatani, Katsuyoshi Ando, Nobuhiro Ueno, Shin Kashima, Kentaro Moriichi, Hiroki Tanabe, Toshikatsu Okumura

Int J Mol Sci. 2020 Jun; 21(12): 4514. Published online 2020 Jun 25. doi: 10.3390/ijms21124514

PMCID:: PMC7350029

Abstract Article PDF–2.4M

Select item 57425147.

Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells

Anja Schwiebs, Dominique Thomas, Burkhard Kleuser, Josef M. Pfeilschifter, Heinfried H. Radeke

Mediators Inflamm. 2017; 2017: 5187368. Published online 2017 Dec 11. doi: 10.1155/2017/5187368

PMCID:: PMC5742514

Abstract Article PDF–2.3M

Select item 56069968.

Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements

Leila Pirhaji, Pamela Milani, Simona Dalin, Brook T. Wassie, Denise E. Dunn, Robert J. Fenster, Julian Avila-Pacheco, Paul Greengard, Clary B. Clish, Myriam Heiman, Donald C. Lo, Ernest Fraenkel

Nat Commun. 2017; 8: 623. Published online 2017 Sep 20. doi: 10.1038/s41467-017-00353-6

PMCID:: PMC5606996

Abstract Article PDF–3.3M

Select item 53307449.

Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome

Rathi Prasad, Irene Hadjidemetriou, Avinaash Maharaj, Eirini Meimaridou, Federica Buonocore, Moin Saleem, Jenny Hurcombe, Agnieszka Bierzynska, Eliana Barbagelata, Ignacio Bergadá, Hamilton Cassinelli, Urmi Das, GOSgene, Ruth Krone, Bulent Hacihamdioglu, Erkan Sari, Ediz Yesilkaya, Helen L. Storr, Maria Clemente, Monica Fernandez-Cancio, Nuria Camats, Nanik Ram, John C. Achermann, Paul P. Van Veldhoven, Leonardo Guasti, Debora Braslavsky, Tulay Guran, Louise A. Metherell

J Clin Invest. 2017 Mar 1; 127(3): 942–953. Published online 2017 Feb 6. doi: 10.1172/JCI90171

PMCID:: PMC5330744

Abstract Article PDF–3.5M

Select item 391248710.

Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease

Johnatan Ceccom, Najat Loukh, Valérie Lauwers-Cances, Christian Touriol, Yvan Nicaise, Catherine Gentil, Emmanuelle Uro-Coste, Stuart Pitson, Claude Alain Maurage, Charles Duyckaerts, Olivier Cuvillier, Marie-Bernadette Delisle

Acta Neuropathol Commun. 2014; 2: 12. Published online 2014 Jan 27. doi: 10.1186/2051-5960-2-12

PMCID:: PMC3912487

Abstract Article PDF–1.4M

Select item 310170311.

S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism

A Kumar, B Oskouian, H Fyrst, M Zhang, F Paris, J D Saba

Cell Death Dis. 2011 Feb; 2(2): e119. Published online 2011 Feb 10. doi: 10.1038/cddis.2011.3

PMCID:: PMC3101703

Abstract Article PDF–795K

Select item 303158512.

Intracellular S1P Generation Is Essential for S1P-Induced Motility of Human Lung Endothelial Cells: Role of Sphingosine Kinase 1 and S1P Lyase

Evgeny V. Berdyshev, Irina Gorshkova, Peter Usatyuk, Satish Kalari, Yutong Zhao, Nigel J. Pyne, Susan Pyne, Roger A. Sabbadini, Joe G. N. Garcia, Viswanathan Natarajan

PLoS One. 2011; 6(1): e16571. Published online 2011 Jan 31. doi: 10.1371/journal.pone.0016571

PMCID:: PMC3031585

Abstract Article PDF–3.0M

Select item 291654213.

Sphingosine 1-Phosphate-Metabolizing Enzymes Control Influenza Virus Propagation and Viral Cytopathogenicity

Young-Jin Seo, Celeste Blake, Stephen Alexander, Bumsuk Hahm

J Virol. 2010 Aug; 84(16): 8124–8131. Published online 2010 Jun 2. doi: 10.1128/JVI.00510-10

PMCID:: PMC2916542

Abstract Article PDF–1.2M

Select item 260602414.

Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions

Peter Vogel, Michael S. Donoviel, Robert Read, Gwenn M. Hansen, Jill Hazlewood, Stephen J. Anderson, Weimei Sun, Jonathan Swaffield, Tamas Oravecz

PLoS One. 2009; 4(1): e4112. Published online 2009 Jan 1. doi: 10.1371/journal.pone.0004112

PMCID:: PMC2606024

Abstract Article PDF–1.5M

Select item 996523815.

Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation

Faik Imeri, Bisera Stepanovska Tanturovska, Roxana Manaila, Hermann Pavenstädt, Josef Pfeilschifter, Andrea Huwiler

Int J Mol Sci. 2023 Feb; 24(4): 3267. Published online 2023 Feb 7. doi: 10.3390/ijms24043267

PMCID:: PMC9965238

Abstract Article PDF–2.3M

Select item 759981616.

Neurodegeneration Caused by S1P-Lyase Deficiency Involves Calcium-Dependent Tau Pathology and Abnormal Histone Acetylation

Shah Alam, Antonia Piazzesi, Mariam Abd El Fatah, Maren Raucamp, Gerhild van Echten-Deckert

Cells. 2020 Oct; 9(10): 2189. Published online 2020 Sep 28. doi: 10.3390/cells9102189

PMCID:: PMC7599816

Abstract Article PDF–2.5M

Select item 526849317.

Synergistic Action of Genistein and Calcitriol in Immature Osteosarcoma MG-63 Cells by SGPL1 Up-Regulation

Nadja Engel, Anna Adamus, Nicolas Schauer, Juliane Kühn, Barbara Nebe, Guido Seitz, Karin Kraft

PLoS One. 2017; 12(1): e0169742. Published online 2017 Jan 26. doi: 10.1371/journal.pone.0169742

PMCID:: PMC5268493

Abstract Article PDF–3.0M

Select item 514784618.

miR-125b Enhances IL-8 Production in Early-Onset Severe Preeclampsia by Targeting Sphingosine-1-Phosphate Lyase 1

Weiwei Yang, Anning Wang, Chunling Zhao, Qinghua Li, Zhifang Pan, Xuefu Han, Cuijuan Zhang, Guohui Wang, Chao Ji, Guili Wang, Guangtao Jia, Jiyu Ju, Wei Gao, Wenjing Yu, Xiaoying Liu, Xi Chen, Weiguo Feng, Zhiqin Gao, Jie Li, Chune Ren

PLoS One. 2016; 11(12): e0166940. Published online 2016 Dec 9. doi: 10.1371/journal.pone.0166940

PMCID:: PMC5147846

Abstract Article PDF–2.2M

Select item 486198019.

Aberrant expression of the S1P regulating enzymes, SPHK1 and SGPL1, contributes to a migratory phenotype in OSCC mediated through S1PR2

Sathya Narayanan Patmanathan, Steven P. Johnson, Sook Ling Lai, Suthashini Panja Bernam, Victor Lopes, Wenbin Wei, Maha Hafez Ibrahim, Federico Torta, Pradeep Narayanaswamy, Markus R. Wenk, Deron R. Herr, Paul G. Murray, Lee Fah Yap, Ian C. Paterson

Sci Rep. 2016; 6: 25650. Published online 2016 May 10. doi: 10.1038/srep25650

PMCID:: PMC4861980

Abstract Article PDF–1.5M

Select item 475738820.

Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence

Baasanjav Uranbileg, Hitoshi Ikeda, Makoto Kurano, Kenichiro Enooku, Masaya Sato, Daisuke Saigusa, Junken Aoki, Takeaki Ishizawa, Kiyoshi Hasegawa, Norihiro Kokudo, Yutaka Yatomi

PLoS One. 2016; 11(2): e0149462. Published online 2016 Feb 17. doi: 10.1371/journal.pone.0149462

PMCID:: PMC4757388

Abstract Article PDF–1.1M

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