PMC Links for Gene (Select 91012) - PMC

Select item 36899211.

Ceramide synthases at the centre of sphingolipid metabolism and biology

Thomas D. Mullen, Yusuf A. Hannun, Lina M. Obeid

Biochem J. Author manuscript; available in PMC 2013 Jun 22.

Published in final edited form as: Biochem J. 2012 Feb 1; 441(3): 789–802. doi: 10.1042/BJ20111626

PMCID:: PMC3689921

Select item 48072832.

Ceramide Synthase 5 Is Essential to Maintain C_16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity

Dominic Gosejacob, Philipp S. Jäger, Katharina vom Dorp, Martin Frejno, Anne C. Carstensen, Monika Köhnke, Joachim Degen, Peter Dörmann, Michael Hoch

J Biol Chem. 2016 Mar 25; 291(13): 6989–7003. Published online 2016 Feb 7. doi: 10.1074/jbc.M115.691212

PMCID:: PMC4807283

Abstract Article PDF–4.1M

Select item 25465493.

Ceramide Generated by Sphingomyelin Hydrolysis and the Salvage Pathway Is Involved in Hypoxia/Reoxygenation-induced Bax Redistribution to Mitochondria in NT-2 Cells

Junfei Jin, Qi Hou, Thomas D. Mullen, Youssef H. Zeidan, Jacek Bielawski, Jacqueline M. Kraveka, Alicja Bielawska, Lina M. Obeid, Yusuf A. Hannun, Yi-Te Hsu

J Biol Chem. 2008 Sep 26; 283(39): 26509–26517. doi: 10.1074/jbc.M801597200

PMCID:: PMC2546549

Abstract Article PDF–638K

Select item 43480054.

Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells

Judith Mesicek, Hyunmi Lee, Taya Feldman, Xuejun Jiang, Anastasia Skobeleva, Evgeny V. Berdyshev, Adriana Haimovitz-Friedman, Zvi Fuks, Richard Kolesnick

Cell Signal. Author manuscript; available in PMC 2015 Mar 3.

Published in final edited form as: Cell Signal. 2010 Sep; 22(9): 1300–1307. Published online 2010 Apr 18. doi: 10.1016/j.cellsig.2010.04.006

PMCID:: PMC4348005

Abstract Article PDF–933K

Select item 52800745.

LASS5 Interacts with SDHB and Synergistically Represses p53 and p21 Activity

Z. Jiang, F. Li, Y. Wan, Z. Han, W. Yuan, L. Cao, Y. Deng, X. Peng, F. Chen, X. Fan, X. Liu, G. Dai, Y. Wang, Q. Zeng, Y. Shi, Z. Zhou, Y. Chen, W. Xu, S. Luo, S. Chen, X. Ye, X. Mo, X. Wu, Y. Li

Curr Mol Med. Author manuscript; available in PMC 2017 Jan 30.

Published in final edited form as: Curr Mol Med. 2016; 16(6): 582–590. doi: 10.2174/1566524016666160607090012

PMCID:: PMC5280074

Abstract Article PDF–618K

Select item 60164656.

Eleven residues determine the acyl chain specificity of ceramide synthases

Rotem Tidhar, Iris D. Zelnik, Giora Volpert, Shifra Ben-Dor, Samuel Kelly, Alfred H. Merrill, Jr., Anthony H. Futerman

J Biol Chem. 2018 Jun 22; 293(25): 9912–9921. Published online 2018 Apr 9. doi: 10.1074/jbc.RA118.001936

PMCID:: PMC6016465

Abstract Article PDF–2.3M

Select item 48171787.

Enzyme Activities of the Ceramide Synthases CERS2–6 Are Regulated by Phosphorylation in the C-terminal Region

Takayuki Sassa, Taisuke Hirayama, Akio Kihara

J Biol Chem. 2016 Apr 1; 291(14): 7477–7487. Published online 2016 Feb 17. doi: 10.1074/jbc.M115.695858

PMCID:: PMC4817178

Abstract Article PDF–1.8M

Select item 72067938.

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling

Jin Huk Choi, Xue Zhong, William McAlpine, Tzu-Chieh Liao, Duanwu Zhang, Beibei Fang, Jamie Russell, Sara Ludwig, Evan Nair-Gill, Zhao Zhang, Kuan-wen Wang, Takuma Misawa, Xiaoming Zhan, Mihwa Choi, Tao Wang, Xiaohong Li, Miao Tang, Qihua Sun, Liyang Yu, Anne R. Murray, Eva Marie Y. Moresco, Bruce Beutler

Science. Author manuscript; available in PMC 2020 May 8.

Published in final edited form as: Science. 2019 May 10; 364(6440): eaau0812. doi: 10.1126/science.aau0812

PMCID:: PMC7206793

Abstract Article PDF–2.2M

Select item 92316239.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 911973610.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 135612911.

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano

Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406

PMCID:: PMC1356129

Abstract Article PDF–438K

Select item 461721112.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011