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1.
Monocarboxylate transporter 4 (MCT4) is a high affinity transporter capable of exporting lactate in high-lactate microenvironments
Yasna Contreras-Baeza, Pamela Y. Sandoval, Romina Alarcón, Alex Galaz, Francisca Cortés-Molina, Karin Alegría, Felipe Baeza-Lehnert, Robinson Arce-Molina, Anita Guequén, Carlos A. Flores, Alejandro San Martín, L. Felipe Barros
J Biol Chem. 2019 Dec 27; 294(52): 20135–20147. Published online 2019 Nov 12. doi: 10.1074/jbc.RA119.009093
PMCID:
PMC6937558
AbstractArticlePDF–2.4M
2.
Downregulation of MCT4 for lactate exchange promotes the cytotoxicity of NK cells in breast carcinoma
Yaping Long, Zihe Gao, Xiao Hu, Feng Xiang, Zhaozhen Wu, Jiahui Zhang, Xiao Han, Liyong Yin, Junfang Qin, Lan Lan, Fuzai Yin, Yue Wang
Cancer Med. 2018 Sep; 7(9): 4690–4700. Published online 2018 Jul 26. doi: 10.1002/cam4.1713
PMCID:
PMC6143925
AbstractArticlePDF–1.1M
3.
Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4)
Kerstin Ziegler, Asimina Kerimi, Laure Poquet, Gary Williamson
Arch Biochem Biophys. 2016 Jun 1; 599: 3–12. doi: 10.1016/j.abb.2016.01.018
PMCID:
PMC4884672
AbstractArticle
4.
Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia
John J. Castorino, Sylvie Deborde, Ami Deora, Ryan Schreiner, Shannon M. Gallagher-Colombo, Enrique Rodriguez-Boulan, Nancy J. Philp
Traffic. Author manuscript; available in PMC 2012 Apr 1.
Published in final edited form as: Traffic. 2011 Apr; 12(4): 483–498. Published online 2011 Feb 1. doi: 10.1111/j.1600-0854.2010.01155.x
PMCID:
PMC3132080
AbstractArticlePDF–3.9M
5.
Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle
Jocelyn E Manning Fox, David Meredith, Andrew P Halestrap
J Physiol. 2000 Dec 1; 529(Pt 2): 285–293. doi: 10.1111/j.1469-7793.2000.00285.x
PMCID:
PMC2270204
AbstractArticlePDF–277K
6.
Identification and Validation of a Prognostic Model Based on Three MVI-Related Genes in Hepatocellular Carcinoma
Yongchang Tang, Lei Xu, Yupeng Ren, Yuxuan Li, Feng Yuan, Mingbo Cao, Yong Zhang, Meihai Deng, Zhicheng Yao
Int J Biol Sci. 2022; 18(1): 261–275. Published online 2022 Jan 1. doi: 10.7150/ijbs.66536
PMCID:
PMC8692135
AbstractArticlePDF–2.9M
7.
Hyaluronan, CD44, and Emmprin Regulate Lactate Efflux and Membrane Localization of Monocarboxylate Transporters in Human Breast Carcinoma Cells
Mark G. Slomiany, G. Daniel Grass, Angela D. Robertson, Xiao Y. Yang, Bernard L. Maria, Craig Beeson, Bryan P. Toole
Cancer Res. Author manuscript; available in PMC 2013 May 16.
Published in final edited form as: Cancer Res. 2009 Feb 15; 69(4): 1293–1301. Published online 2009 Jan 27. doi: 10.1158/0008-5472.CAN-08-2491
PMCID:
PMC3655770
AbstractArticlePDF–2.7M
8.
CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
P. Kirk, M.C. Wilson, C. Heddle, M.H. Brown, A.N. Barclay, A.P. Halestrap
EMBO J. 2000 Aug 1; 19(15): 3896–3904. doi: 10.1093/emboj/19.15.3896
PMCID:
PMC306613
AbstractArticlePDF–865K
9.
Cloning and sequencing of four new mammalian monocarboxylate transporter (MCT) homologues confirms the existence of a transporter family with an ancient past.
N T Price, V N Jackson, A P Halestrap
Biochem J. 1998 Jan 15; 329(Pt 2): 321–328. doi: 10.1042/bj3290321
PMCID:
PMC1219047
SummaryPDF–817K
10.
The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation.
A P Halestrap, N T Price
Biochem J. 1999 Oct 15; 343(Pt 2): 281–299.
PMCID:
PMC1220552
SummaryPDF–389K
11.
ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response
Lufen Chang, Lei Shen, Hu Zhou, Jing Gao, Hangyi Pan, Li Zheng, Brian Armstrong, Yang Peng, Guang Peng, Binhua P Zhou, Steven T Rosen, Binghui Shen
Nucleic Acids Res. 2019 Jan 25; 47(2): 824–842. Published online 2018 Dec 4. doi: 10.1093/nar/gky1199
PMCID:
PMC6344871
AbstractArticlePDF–6.8M
12.
Proteome‐wide analysis of phospho‐regulated PDZ domain interactions
Gustav N Sundell, Roland Arnold, Muhammad Ali, Piangfan Naksukpaiboon, Julien Orts, Peter Güntert, Celestine N Chi, Ylva Ivarsson
Mol Syst Biol. 2018 Aug; 14(8): e8129. Published online 2018 Aug 20. doi: 10.15252/msb.20178129
PMCID:
PMC6100724
AbstractArticlePDF–2.4M
13.
Folate receptor α increases chemotherapy resistance through stabilizing MDM2 in cooperation with PHB2 that is overcome by MORAb‐202 in gastric cancer
Hitomi Sakai, Hisato Kawakami, Takeshi Teramura, Yuta Onodera, Elizabeth Somers, Keiji Furuuchi, Toshimitsu Uenaka, Ryoji Kato, Kazuhiko Nakagawa
Clin Transl Med. 2021 Jun; 11(6): e454. Published online 2021 Jun 1. doi: 10.1002/ctm2.454
PMCID:
PMC8167866
AbstractArticlePDF–7.0M
14.
Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD–associated UBQLN2 mutants
Laura Strohm, Zehan Hu, Yongwon Suk, Alina Rühmkorf, Erin Sternburg, Vanessa Gattringer, Henrick Riemenschneider, Riccardo Berutti, Elisabeth Graf, Jochen H Weishaupt, Monika S Brill, Angelika B Harbauer, Dorothee Dormann, Jörn Dengjel, Dieter Edbauer, Christian Behrends
Life Sci Alliance. 2022 Nov; 5(11): e202101327. Published online 2022 Jul 1. doi: 10.26508/lsa.202101327
PMCID:
PMC9258132
AbstractArticlePDF–5.9M
15.
The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer
Weimei Tang, Weijie Zhou, Li Xiang, Xiaosheng Wu, Pei Zhang, Jing Wang, Guangnan Liu, Wenjing Zhang, Ying Peng, Xiaoting Huang, Jianqun Cai, Yang Bai, Lan Bai, Wei Zhu, Hongxiang Gu, Jing Xiong, Chen Ye, Aimin Li, Side Liu, Jide Wang
Nat Commun. 2019; 10: 663. Published online 2019 Feb 8. doi: 10.1038/s41467-018-08225-3
PMCID:
PMC6368584
AbstractArticlePDF–6.8M
16.
TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT–GSK-3β–β-Catenin Signaling Pathway
Shiyu Chen, Zhiwei He, Changhao Zhu, Yanqing Liu, Lin Li, Lu Deng, Jun Wang, Chao Yu, Chengyi Sun
Front Oncol. 2020; 10: 554787. Published online 2020 Oct 16. doi: 10.3389/fonc.2020.554787
PMCID:
PMC7651862
AbstractArticlePDF–5.4M
17.
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell
J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468
PMCID:
PMC10323252
AbstractArticle
18.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
PMCID:
PMC10916866
AbstractArticlePDF–4.7M
19.
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export
Dick J. H. van den Boomen, Agata Sienkiewicz, Ilana Berlin, Marlieke L. M. Jongsma, Daphne M. van Elsland, J. Paul Luzio, Jacques J. C. Neefjes, Paul J. Lehner
Nat Commun. 2020; 11: 5559. Published online 2020 Nov 3. doi: 10.1038/s41467-020-19032-0
PMCID:
PMC7642327
AbstractArticlePDF–12M
20.
Interpreting cancer genomes using systematic host perturbations by tumour virus proteins
Orit Rozenblatt-Rosen, Rahul C. Deo, Megha Padi, Guillaume Adelmant, Michael A. Calderwood, Thomas Rolland, Miranda Grace, Amélie Dricot, Manor Askenazi, Maria Tavares, Sam Pevzner, Fieda Abderazzaq, Danielle Byrdsong, Anne-Ruxandra Carvunis, Alyce A. Chen, Jingwei Cheng, Mick Correll, Melissa Duarte, Changyu Fan, Mariet C. Feltkamp, Scott B. Ficarro, Rachel Franchi, Brijesh K. Garg, Natali Gulbahce, Tong Hao, Amy M. Holthaus, Robert James, Anna Korkhin, Larisa Litovchick, Jessica C. Mar, Theodore R. Pak, Sabrina Rabello, Renee Rubio, Yun Shen, Saurav Singh, Jennifer M. Spangle, Murat Tasan, Shelly Wanamaker, James T. Webber, Jennifer Roecklein-Canfield, Eric Johannsen, Albert-László Barabási, Rameen Beroukhim, Elliott Kieff, Michael E. Cusick, David E. Hill, Karl Münger, Jarrod A. Marto, John Quackenbush, Frederick P. Roth, James A. DeCaprio, Marc Vidal
Nature. Author manuscript; available in PMC 2013 Jan 26.
Published in final edited form as: Nature. 2012 Jul 26; 487(7408): 491–495. doi: 10.1038/nature11288
PMCID:
PMC3408847
AbstractArticlePDF–937K

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