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Items: 1 to 20 of 84

1.
Escherichia coli GyrA Tower Domain Interacts with QnrB1 Loop B and Plays an Important Role in QnrB1 Protection from Quinolone Inhibition
Chunhui Chen, Yin Wang, Hidemasa Nakaminami, Eu Suk Kim, George A. Jacoby, David C. Hooper
Antimicrob Agents Chemother. 2021 Jul; 65(7): e00402-21. Prepublished online 2021 Apr 12. Published online 2021 Jun 17. doi: 10.1128/AAC.00402-21
PMCID:
PMC8373224
AbstractArticlePDF–740K
2.
Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase
Matthew J Hobson, Zev Bryant, James M Berger
Nucleic Acids Res. 2020 Feb 28; 48(4): 2035–2049. Published online 2020 Jan 17. doi: 10.1093/nar/gkz1230
PMCID:
PMC7038939
AbstractArticlePDF–7.0M
3.
Single-molecule imaging of DNA gyrase activity in living Escherichia coli
Mathew Stracy, Adam J M Wollman, Elzbieta Kaja, Jacek Gapinski, Ji-Eun Lee, Victoria A Leek, Shannon J McKie, Lesley A Mitchenall, Anthony Maxwell, David J Sherratt, Mark C Leake, Pawel Zawadzki
Nucleic Acids Res. 2019 Jan 10; 47(1): 210–220. Published online 2018 Nov 16. doi: 10.1093/nar/gky1143
PMCID:
PMC6326794
AbstractArticlePDF–1.2M
4.
Inhibition of the gyrA promoter by transcription-coupled DNA supercoiling in Escherichia coli
Samantha Dages, Kelley Dages, Xiaoduo Zhi, Fenfei Leng
Sci Rep. 2018; 8: 14759. Published online 2018 Oct 3. doi: 10.1038/s41598-018-33089-4
PMCID:
PMC6170449
AbstractArticlePDF–2.5M
5.
Analytical profiling of mutations in quinolone resistance determining region of gyrA gene among UPEC
Lesley R. Varughese, Meenakshi Rajpoot, Soniya Goyal, Ravinder Mehra, Vinod Chhokar, Vikas Beniwal
PLoS One. 2018; 13(1): e0190729. Published online 2018 Jan 4. doi: 10.1371/journal.pone.0190729
PMCID:
PMC5754135
AbstractArticlePDF–8.3M
6.
A New Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8 Bound to DNA Gyrase Gives Fresh Insight into the Mechanism of Inhibition
Stephen J. Hearnshaw, Marcus J. Edwards, Clare E. Stevenson, David M. Lawson, Anthony Maxwell
J Mol Biol. 2014 May 15; 426(10): 2023–2033. doi: 10.1016/j.jmb.2014.02.017
PMCID:
PMC4018983
AbstractArticle
7.
Driving Forces of Gyrase Recognition by the Addiction Toxin CcdB
Mario Simic, Natalie De Jonge, Remy Loris, Gorazd Vesnaver, Jurij Lah
J Biol Chem. 2009 Jul 24; 284(30): 20002–20010. Published online 2009 May 22. doi: 10.1074/jbc.M109.014035
PMCID:
PMC2740426
AbstractArticlePDF–2.1M
8.
Crystallization and preliminary X-ray analysis of a complex formed between the antibiotic simocyclinone D8 and the DNA breakage–reunion domain of Escherichia coli DNA gyrase
Marcus J. Edwards, Ruth H. Flatman, Lesley A. Mitchenall, Clare E. M. Stevenson, Anthony Maxwell, David M. Lawson
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Aug 1; 65(Pt 8): 846–848. Published online 2009 Jul 30. doi: 10.1107/S1744309109028097
PMCID:
PMC2720350
AbstractArticlePDF–117K
9.
Escherichia coli with a linear genome
Tailin Cui, Naoki Moro-oka, Katsufumi Ohsumi, Kenichi Kodama, Taku Ohshima, Naotake Ogasawara, Hirotada Mori, Barry Wanner, Hironori Niki, Takashi Horiuchi
EMBO Rep. 2007 Feb; 8(2): 181–187. Published online 2007 Jan 12. doi: 10.1038/sj.embor.7400880
PMCID:
PMC1796773
AbstractArticlePDF–279K
10.
Different Modes of Action of Naphthyridones in Gram-Positive and Gram-Negative Bacteria
Ed T. Buurman, Kenneth D. Johnson, Roxanne K. Kelly, Kathy MacCormack
Antimicrob Agents Chemother. 2006 Jan; 50(1): 385–387. doi: 10.1128/AAC.50.1.385-387.2006
PMCID:
PMC1346805
AbstractArticlePDF–87K
11.
A Mutation in Escherichia coli DNA Gyrase Conferring Quinolone Resistance Results in Sensitivity to Drugs Targeting Eukaryotic Topoisomerase II
Thomas Gruger, John L. Nitiss, Anthony Maxwell, E. Lynn Zechiedrich, Peter Heisig, Siegfried Seeber, Yves Pommier, Dirk Strumberg
Antimicrob Agents Chemother. 2004 Dec; 48(12): 4495–4504. doi: 10.1128/AAC.48.12.4495-4504.2004
PMCID:
PMC529191
AbstractArticlePDF–499K
12.
Studies on the Mechanism of Action of Nalidixic Acid
Gerard J. Bourguignon, Martin Levitt, Rolf Sternglanz
Antimicrob Agents Chemother. 1973 Oct; 4(4): 479–486. doi: 10.1128/aac.4.4.479
PMCID:
PMC444580
SummaryPage BrowsePDF–1.1M
13.
The C-terminal domain of DNA gyrase A adopts a DNA-bending β-pinwheel fold
Kevin D. Corbett, Ryan K. Shultzaberger, James M. Berger
Proc Natl Acad Sci U S A. 2004 May 11; 101(19): 7293–7298. Published online 2004 May 3. doi: 10.1073/pnas.0401595101
PMCID:
PMC409912
AbstractArticlePDF–557K
14.
The C-terminal domain of the Escherichia coli DNA gyrase A subunit is a DNA-binding protein.
R J Reece, A Maxwell
Nucleic Acids Res. 1991 Apr 11; 19(7): 1399–1405. doi: 10.1093/nar/19.7.1399
PMCID:
PMC333892
SummaryPage BrowsePDF–1.7M
15.
Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones.
M E Cullen, A W Wyke, R Kuroda, L M Fisher
Antimicrob Agents Chemother. 1989 Jun; 33(6): 886–894. doi: 10.1128/aac.33.6.886
PMCID:
PMC284251
SummaryPage BrowsePDF–2.0M
16.
Escherichia coli K-12 Mutants Resistant to Nalidixic Acid: Genetic Mapping and Dominance Studies
Michael W. Hane, Thomas H. Wood
J Bacteriol. 1969 Jul; 99(1): 238–241. doi: 10.1128/jb.99.1.238-241.1969
PMCID:
PMC249993
SummaryPage BrowsePDF–526K
17.
4-Quinolone resistance mutations in the DNA gyrase of Escherichia coli clinical isolates identified by using the polymerase chain reaction.
M Oram, L M Fisher
Antimicrob Agents Chemother. 1991 Feb; 35(2): 387–389. doi: 10.1128/aac.35.2.387
PMCID:
PMC245014
SummaryPage BrowsePDF–731K
18.
Novel quinolone resistance mutations of the Escherichia coli DNA gyrase A protein: enzymatic analysis of the mutant proteins.
P Hallett, A Maxwell
Antimicrob Agents Chemother. 1991 Feb; 35(2): 335–340. doi: 10.1128/aac.35.2.335
PMCID:
PMC245001
SummaryPage BrowsePDF–1.4M
19.
Enhanced Resistance to Nitrosoguanidine Killing and Mutagenesis in a DNA Gyrase Mutant of Escherichia coli
Lee Chao, D. Michael Tillman
J Bacteriol. 1982 Aug; 151(2): 764–770. doi: 10.1128/jb.151.2.764-770.1982
PMCID:
PMC220323
SummaryPage BrowsePDF–1.2M
20.
Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth
Kenneth N. Kreuzer, Nicholas R. Cozzarelli
J Bacteriol. 1979 Nov; 140(2): 424–435. doi: 10.1128/jb.140.2.424-435.1979
PMCID:
PMC216666
SummaryPage BrowsePDF–2.0M

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