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Items: 1 to 20 of 61

1.
Single-molecule view of coordination in a multi-functional DNA polymerase
Raymond F Pauszek, III, Rajan Lamichhane, Arishma Rajkarnikar Singh, David P Millar
eLife. 2021; 10: e62046. Published online 2021 Mar 11. doi: 10.7554/eLife.62046
PMCID:
PMC7952088
AbstractArticlePDF–2.3M
2.
Role of High-Fidelity Escherichia coli DNA Polymerase I in Replication Bypass of a Deoxyadenosine DNA-Peptide Cross-Link
Kinrin Yamanaka, Irina G. Minko, Steven E. Finkel, Myron F. Goodman, R. Stephen Lloyd
J Bacteriol. 2011 Aug; 193(15): 3815–3821. doi: 10.1128/JB.01550-10
PMCID:
PMC3147505
AbstractArticlePDF–649K
3.
Distinct Complexes of DNA Polymerase I (Klenow Fragment) for Base and Sugar Discrimination during Nucleotide Substrate Selection
Daniel R. Garalde, Christopher A. Simon, Joseph M. Dahl, Hongyun Wang, Mark Akeson, Kate R. Lieberman
J Biol Chem. 2011 Apr 22; 286(16): 14480–14492. Published online 2011 Feb 28. doi: 10.1074/jbc.M111.218750
PMCID:
PMC3077647
AbstractArticlePDF–1.9M
4.
Monitoring the Conformation of Benzo[a]pyrene Adducts in the Polymerase Active Site using Fluorescence Resonance Energy Transfer
Thomas D. Christian, Louis J. Romano
Biochemistry. Author manuscript; available in PMC 2010 May 4.
Published in final edited form as: Biochemistry. 2009 Jun 16; 48(23): 5382–5388. doi: 10.1021/bi900148t
PMCID:
PMC2864109
AbstractArticlePDF–1.2M
5.
Role of Escherichia coli DNA Polymerase I in chromosomal DNA replication fidelity
Karolina Makiela-Dzbenska, Malgorzata Jaszczur, Magdalena Banach-Orlowska, Piotr Jonczyk, Roel M. Schaaper, Iwona J. Fijalkowska
Mol Microbiol. Author manuscript; available in PMC 2010 Dec 1.
Published in final edited form as: Mol Microbiol. 2009 Dec; 74(5): 1114–1127. Published online 2009 Oct 19. doi: 10.1111/j.1365-2958.2009.06921.x
PMCID:
PMC2818720
AbstractArticlePDF–509K
6.
The Mechanism and Dynamics of Translesion DNA Synthesis Catalyzed by the Escherichia coli Klenow fragment
Asim Sheriff, Edward Motea, Irene Lee, Anthony J. Berdis
Biochemistry. Author manuscript; available in PMC 2009 Jun 8.
Published in final edited form as: Biochemistry. 2008 Aug 19; 47(33): 8527–8537. Published online 2008 Jul 25. doi: 10.1021/bi800324r
PMCID:
PMC2692461
AbstractArticlePDF–1.6M
7.
The Unnatural Substrate Repertoire of A, B, and X Family DNA Polymerases
Gil Tae Hwang, Floyd E. Romesberg
J Am Chem Soc. Author manuscript; available in PMC 2009 Nov 5.
Published in final edited form as: J Am Chem Soc. 2008 Nov 5; 130(44): 14872–14882. Published online 2008 Oct 11. doi: 10.1021/ja803833h
PMCID:
PMC2675700
AbstractArticlePDF–393K
8.
DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: Analysis by single-turnover kinetics
Olga Potapova, Chikio Chan, Angela M. DeLucia, Sandra A. Helquist, Eric T. Kool, Nigel D. F. Grindley, Catherine M. Joyce
Biochemistry. Author manuscript; available in PMC 2008 Oct 15.
Published in final edited form as: Biochemistry. 2006 Jan 24; 45(3): 890–898. doi: 10.1021/bi051792i
PMCID:
PMC2567902
AbstractArticlePDF–1.2M
9.
Identification of a New Motif Required for the 3′–5′ Exonuclease Activity of Escherichia coli DNA Polymerase I (Klenow Fragment): THE RRRY MOTIF IS NECESSARY FOR THE BINDING OF SINGLE-STRANDED DNA SUBSTRATE AND THE TEMPLATE STRAND OF THE MISMATCHED DUPLEX
Pinky Kukreti, Kamalendra Singh, Amit Ketkar, Mukund J. Modak
J Biol Chem. 2008 Jun 27; 283(26): 17979–17990. doi: 10.1074/jbc.M801053200
PMCID:
PMC2440594
AbstractArticlePDF–687K
10.
Probing the active site tightness of DNA polymerase in subangstrom increments
Tae Woo Kim, James C. Delaney, John M. Essigmann, Eric T. Kool
Proc Natl Acad Sci U S A. 2005 Nov 1; 102(44): 15803–15808. Published online 2005 Oct 25. doi: 10.1073/pnas.0505113102
PMCID:
PMC1276059
AbstractArticlePDF–523K
11.
Mapping of the polA Locus of ESCHERICHIA COLI K12: Genetic Fine Structure of the Cistron
William S. Kelley
Genetics. 1980 May; 95(1): 15–38. doi: 10.1093/genetics/95.1.15
PMCID:
PMC1214213
SummaryPDF–1.6M
12.
Exploration of factors driving incorporation of unnatural dNTPS into DNA by Klenow fragment (DNA polymerase I) and DNA polymerase α
Kristi Kincaid, Jeff Beckman, Aleksandra Zivkovic, Randall L. Halcomb, Joachim W. Engels, Robert D. Kuchta
Nucleic Acids Res. 2005; 33(8): 2620–2628. Published online 2005 May 6. doi: 10.1093/nar/gki563
PMCID:
PMC1090547
AbstractArticlePDF–291K
13.
Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli.
C M Joyce, N D Grindley
Proc Natl Acad Sci U S A. 1983 Apr; 80(7): 1830–1834. doi: 10.1073/pnas.80.7.1830
PMCID:
PMC393703
SummaryPage BrowsePDF–1.2M
14.
A Conditional Lethal Mutant of Escherichia coli K12 Defective in the 5′ → 3′ Exonuclease Associated with DNA Polymerase I
E. Bruce Konrad, I. R. Lehman
Proc Natl Acad Sci U S A. 1974 May; 71(5): 2048–2051. doi: 10.1073/pnas.71.5.2048
PMCID:
PMC388383
SummaryPage BrowsePDF–711K
15.
DNA polymerase I and a protein complex bind specifically to E. coli palindromic unit highly repetitive DNA: implications for bacterial chromosome organization.
E Gilson, D Perrin, M Hofnung
Nucleic Acids Res. 1990 Jul 11; 18(13): 3941–3952. doi: 10.1093/nar/18.13.3941
PMCID:
PMC331097
SummaryPage BrowsePDF–3.2M
16.
DNA strand transfer catalyzed by the 5'-3' exonuclease domain of Escherichia coli DNA polymerase I.
W Zhang, D H Evans
Nucleic Acids Res. 1995 Nov 25; 23(22): 4620–4627. doi: 10.1093/nar/23.22.4620
PMCID:
PMC307435
SummaryPage BrowsePDF–2.6M
17.
Method for determining whether a gene of Escherichia coli is essential: application to the polA gene.
C M Joyce, N D Grindley
J Bacteriol. 1984 May; 158(2): 636–643. doi: 10.1128/jb.158.2.636-643.1984
PMCID:
PMC215477
SummaryPage BrowsePDF–1.8M
18.
DNA polymerase I modulates inducible stable DNA replication in Escherichia coli.
T Ruscitti, S Linn
J Bacteriol. 1992 Oct; 174(19): 6311–6313. doi: 10.1128/jb.174.19.6311-6313.1992
PMCID:
PMC207704
SummaryPage BrowsePDF–482K
19.
Suppression of ColE1 high-copy-number mutants by mutations in the polA gene of Escherichia coli.
Y L Yang, B Polisky
J Bacteriol. 1993 Jan; 175(2): 428–437. doi: 10.1128/jb.175.2.428-437.1993
PMCID:
PMC196157
SummaryPage BrowsePDF–2.2M
20.
Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I
Manel Camps, Jussi Naukkarinen, Ben P. Johnson, Lawrence A. Loeb
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9727–9732. Published online 2003 Aug 8. doi: 10.1073/pnas.1333928100
PMCID:
PMC187833
AbstractArticlePDF–413K

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