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Select item 53925651.

Covalently linked HslU hexamers support a probabilistic mechanism that links ATP hydrolysis to protein unfolding and translocation

Vladimir Baytshtok, Jiejin Chen, Steven E. Glynn, Andrew R. Nager, Robert A. Grant, Tania A. Baker, Robert T. Sauer

J Biol Chem. 2017 Apr 7; 292(14): 5695–5704. Published online 2017 Feb 21. doi: 10.1074/jbc.M116.768978

PMCID:: PMC5392565

Abstract Article PDF–1.2M

Select item 33247632.

The I domain of the AAA+ HslUV protease coordinates substrate binding, ATP hydrolysis, and protein degradation

Shankar Sundar, Tania A Baker, Robert T Sauer

Protein Sci. 2012 Feb; 21(2): 188–198. Published online 2011 Nov 18. doi: 10.1002/pro.2001

PMCID:: PMC3324763

Abstract Article PDF–669K

Select item 25171463.

Asymmetric nucleotide transactions of the HslUV protease

Joseph A. Yakamavich, Tania A. Baker, Robert T. Sauer

J Mol Biol. Author manuscript; available in PMC 2009 Jan 25.

Published in final edited form as: J Mol Biol. 2008 Jul 25; 380(5): 946–957. Published online 2008 Jun 4. doi: 10.1016/j.jmb.2008.05.070

PMCID:: PMC2517146

Abstract Article PDF–1.5M

Select item 27851924.

HslVU ATP-dependent Protease Utilizes Maximally Six among Twelve Threonine Active Sites during Proteolysis

Jung Wook Lee, Eunyong Park, Min Sun Jeong, Young Joo Jeon, Soo Hyun Eom, Jae Hong Seol, Chin Ha Chung

J Biol Chem. 2009 Nov 27; 284(48): 33475–33484. Published online 2009 Oct 1. doi: 10.1074/jbc.M109.045807

PMCID:: PMC2785192

Abstract Article PDF–3.0M

Select item 26811745.

Regulation of clpQ⁺Y⁺ (hslV⁺U⁺) Gene Expression in Escherichia coli

Hsiang-Yun Lien, Chien-Hung Yu, Chung-Ming Liou, Whi Fin Wu

Open Microbiol J. 2009; 3: 29–39. Published online 2009 Mar 17. doi: 10.2174/1874285800903010029

PMCID:: PMC2681174

Abstract Article PDF–603K

Select item 4525166.

Identification and characterization of HsIV HsIU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli.

D Missiakas, F Schwager, J M Betton, C Georgopoulos, S Raina

EMBO J. 1996 Dec 16; 15(24): 6899–6909.

PMCID:: PMC452516

Summary Page Browse PDF–2.4M

Select item 2068417.

Adaptation of Escherichia coli to the uncoupler of oxidative phosphorylation 2,4-dinitrophenol.

D J Gage, F C Neidhardt

J Bacteriol. 1993 Nov; 175(21): 7105–7108. doi: 10.1128/jb.175.21.7105-7108.1993

PMCID:: PMC206841

Summary Page Browse PDF–823K

Select item 1242428.

Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY)

Ravishankar Ramachandran, Claudia Hartmann, Hyun Kyu Song, Robert Huber, Matthias Bochtler

Proc Natl Acad Sci U S A. 2002 May 28; 99(11): 7396–7401. Published online 2002 May 21. doi: 10.1073/pnas.102188799

PMCID:: PMC124242

Abstract Article PDF–243K

Select item 391439.

HslV-HslU: A novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome.

M Rohrwild, O Coux, H C Huang, R P Moerschell, S J Yoo, J H Seol, C H Chung, A L Goldberg

Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12): 5808–5813. doi: 10.1073/pnas.93.12.5808

PMCID:: PMC39143

Summary Page Browse PDF–1.6M

Select item 2120910.

Covalent modification of the active site threonine of proteasomal β subunits and the Escherichia coli homolog HslV by a new class of inhibitors

Matthew Bogyo, John S. McMaster, Maria Gaczynska, Domenico Tortorella, Alfred L. Goldberg, Hidde Ploegh

Proc Natl Acad Sci U S A. 1997 Jun 24; 94(13): 6629–6634. doi: 10.1073/pnas.94.13.6629

PMCID:: PMC21209

Abstract Article PDF–399K

Select item 1887811.

Mutational studies on HslU and its docking mode with HslV

Hyun Kyu Song, Claudia Hartmann, Ravishankar Ramachandran, Matthias Bochtler, Raymond Behrendt, Luis Moroder, Robert Huber

Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26): 14103–14108. Published online 2000 Dec 12. doi: 10.1073/pnas.250491797

PMCID:: PMC18878

Abstract Article PDF–853K

Select item 318742812.

Stepwise Activity of ClpY (HslU) Mutants in the Processive Degradation of Escherichia coli ClpYQ (HslUV) Protease Substrates

Fan-Ching Hsieh, Chien-Teh Chen, Yu-Ting Weng, Sheng-Shiang Peng, Yu-Chun Chen, Ling-Yi Huang, Hui-Ting Hu, Yew-Long Wu, Nai-Chun Lin, Whei-Fen Wu

J Bacteriol. 2011 Oct; 193(19): 5465–5476. doi: 10.1128/JB.05128-11

PMCID:: PMC3187428

Abstract Article PDF–1.6M

Select item 269850213.

Characterization of the Escherichia coli ClpY (HslU) Substrate Recognition Site in the ClpYQ (HslUV) Protease Using the Yeast Two-Hybrid System

Hsiang-Yun Lien, Ru-Shan Shy, Sheng-Shiang Peng, Yuei-Long Wu, Yu-Ting Weng, Hsuan-He Chen, Pin-Chih Su, Wei-Fu Ng, Yu-Chun Chen, Pei-Yi Chang, Whei-Fen Wu

J Bacteriol. 2009 Jul; 191(13): 4218–4231. Published online 2009 Apr 24. doi: 10.1128/JB.00089-09

PMCID:: PMC2698502

Abstract Article PDF–1.6M

Select item 17966914.

Synergistic roles of HslVU and other ATP-dependent proteases in controlling in vivo turnover of sigma32 and abnormal proteins in Escherichia coli.

M Kanemori, K Nishihara, H Yanagi, T Yura

J Bacteriol. 1997 Dec; 179(23): 7219–7225. doi: 10.1128/jb.179.23.7219-7225.1997

PMCID:: PMC179669

Summary PDF–889K

Select item 9384415.

Redundant In Vivo Proteolytic Activities of Escherichia coli Lon and the ClpYQ (HslUV) Protease

Whi-Fin Wu, YanNing Zhou, Susan Gottesman

J Bacteriol. 1999 Jun; 181(12): 3681–3687. doi: 10.1128/jb.181.12.3681-3687.1999

PMCID:: PMC93844

Abstract Article PDF–275K

Select item 9384316.

The ATP-Dependent HslVU/ClpQY Protease Participates in Turnover of Cell Division Inhibitor SulA in Escherichia coli

Masaaki Kanemori, Hideki Yanagi, Takashi Yura

J Bacteriol. 1999 Jun; 181(12): 3674–3680. doi: 10.1128/jb.181.12.3674-3680.1999

PMCID:: PMC93843

Abstract Article PDF–806K

Select item 346044817.

Transfer-messenger RNA-SmpB Protein Regulates Ribonuclease R Turnover by Promoting Binding of HslUV and Lon Proteases

Wenxing Liang, Murray P. Deutscher

J Biol Chem. 2012 Sep 28; 287(40): 33472–33479. Published online 2012 Aug 9. doi: 10.1074/jbc.M112.375287

PMCID:: PMC3460448

Abstract Article PDF–2.4M

Select item 2197418.

Lon and Clp family proteases and chaperones share homologous substrate-recognition domains

Catherine K. Smith, Tania A. Baker, Robert T. Sauer

Proc Natl Acad Sci U S A. 1999 Jun 8; 96(12): 6678–6682. doi: 10.1073/pnas.96.12.6678

PMCID:: PMC21974

Abstract Article PDF–154K

Select item 15260119.

Subunit Oligomerization and Substrate Recognition of the Escherichia coli ClpYQ (HslUV) Protease Implicated by In Vivo Protein-Protein Interactions in the Yeast Two-Hybrid System

Yi-Ying Lee, Chiung-Fang Chang, Chueh-Ling Kuo, Meng-Ching Chen, Chien Hung Yu, Pei-I Lin, Whi Fin Wu

J Bacteriol. 2003 Apr; 185(8): 2393–2401. doi: 10.1128/JB.185.8.2393-2401.2003

Correction in:: J Bacteriol. 2004 Apr; 186(7): 2224.

PMCID:: PMC152601

Abstract Article PDF–328K

Select item 270723120.

ATP-dependent Proteases Differ Substantially in Their Ability to Unfold Globular Proteins

Prakash Koodathingal, Neil E. Jaffe, Daniel A. Kraut, Sumit Prakash, Susan Fishbain, Christophe Herman, Andreas Matouschek

J Biol Chem. 2009 Jul 10; 284(28): 18674–18684. Published online 2009 Apr 21. doi: 10.1074/jbc.M900783200

PMCID:: PMC2707231

Abstract Article PDF–1.2M

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