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Select item 93811131.

VPRBP Functions Downstream of the Androgen Receptor and OGT to Restrict p53 Activation in Prostate Cancer

Ninu Poulose, Nicholas Forsythe, Adam Polonski, Gemma Gregg, Sarah Maguire, Marc Fuchs, Sarah Minner, Guido Sauter, Simon S. McDade, Ian G. Mills

Mol Cancer Res. 2022 Jul 6; 20(7): 1047–1060. Published online 2022 Mar 29. doi: 10.1158/1541-7786.MCR-21-0477

PMCID:: PMC9381113

Abstract Article PDF–2.0M

Select item 85915392.

The CRL4^DCAF1 cullin‐RING ubiquitin ligase is activated following a switch in oligomerization state

Weaam I Mohamed, Andreas D Schenk, Georg Kempf, Simone Cavadini, Anja Basters, Alessandro Potenza, Wassim Abdul Rahman, Julius Rabl, Kurt Reichermeier, Nicolas H Thomä

EMBO J. 2021 Nov 15; 40(22): e108008. Published online 2021 Sep 30. doi: 10.15252/embj.2021108008

PMCID:: PMC8591539

Abstract Article PDF–2.2M

Select item 84865653.

VprBP directs epigenetic gene silencing through histone H2A phosphorylation in colon cancer

Nikhil Baban Ghate, Sangnam Kim, Erin Spiller, Sungmin Kim, Yonghwan Shin, Suhn K. Rhie, Goar Smbatyan, Heinz‐Josef Lenz, Shannon M. Mumenthaler, Woojin An

Mol Oncol. 2021 Oct; 15(10): 2801–2817. Published online 2021 Aug 8. doi: 10.1002/1878-0261.13068

PMCID:: PMC8486565

Abstract Article PDF–4.1M

Select item 54178174.

Quantitative Proteomic Approach Identifies Vpr Binding Protein as Novel Host Factor Supporting Influenza A Virus Infections in Human Cells

Anne Sadewasser, Katharina Paki, Katrin Eichelbaum, Boris Bogdanow, Sandra Saenger, Matthias Budt, Markus Lesch, Klaus-Peter Hinz, Andreas Herrmann, Thomas F. Meyer, Alexander Karlas, Matthias Selbach, Thorsten Wolff

Mol Cell Proteomics. 2017 May; 16(5): 728–742. Published online 2017 Mar 13. doi: 10.1074/mcp.M116.065904

PMCID:: PMC5417817

Abstract Article PDF–2.8M

Select item 110712495.

DCAF1 interacts with PARD3 to promote hepatocellular carcinoma progression and metastasis by activating the Akt signaling pathway

Jinyao Zhang, Yuze Shi, Ke Ding, Weiwei Yu, Jianbo He, Beicheng Sun

J Exp Clin Cancer Res. 2024; 43: 136. Published online 2024 May 6. doi: 10.1186/s13046-024-03055-2

PMCID:: PMC11071249

Abstract Article PDF–6.7M

Select item 101105506.

Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer

Nikhil B. Ghate, Sungmin Kim, Yonghwan Shin, Jinman Kim, Michael Doche, Scott Valena, Alan Situ, Sangnam Kim, Suhn K. Rhie, Heinz-Josef Lenz, Tobias S. Ulmer, Shannon M. Mumenthaler, Woojin An

Nat Commun. 2023; 14: 2140. Published online 2023 Apr 17. doi: 10.1038/s41467-023-37883-1

PMCID:: PMC10110550

Abstract Article PDF–2.0M

Select item 100059577.

CircVPRBP inhibits nodal metastasis of cervical cancer by impeding RACK1 O-GlcNAcylation and stability

Chunyu Zhang, Hongye Jiang, Li Yuan, Yuandong Liao, Pan Liu, Qiqiao Du, Chaoyun Pan, Tianyu Liu, Jie Li, Yili Chen, Jiaming Huang, Yanchun Liang, Meng Xia, Manman Xu, Shuhang Qin, Qiaojian Zou, Yunyun Liu, Hua Huang, Yuwen Pan, Jiaying Li, Junxiu Liu, Wei Wang, Shuzhong Yao

Oncogene. 2023; 42(11): 793–807. Published online 2023 Jan 19. doi: 10.1038/s41388-023-02595-9

PMCID:: PMC10005957

Abstract Article PDF–10M

Select item 82223948.

A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry

Yanwen Chen, Travis B. Lear, John W. Evankovich, Mads B. Larsen, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Laura Salminen, Daniel P. Camarco, Karina C. Lockwood, Ferhan Tuncer, Jie Liu, Michael M. Myerburg, John F. McDyer, Yuan Liu, Toren Finkel, Bill B. Chen

Nat Commun. 2021; 12: 3907. Published online 2021 Jun 23. doi: 10.1038/s41467-021-24156-y

PMCID:: PMC8222394

Abstract Article PDF–2.8M

Select item 70681249.

A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axis

Yanwen Chen, John W. Evankovich, Travis B. Lear, Ferhan Tuncer, Jason R. Kennerdell, Daniel P. Camarco, Morgan S. Shishido, Yuan Liu, Bill B. Chen

Redox Biol. 2020 May; 32: 101485. Published online 2020 Mar 4. doi: 10.1016/j.redox.2020.101485

PMCID:: PMC7068124

Abstract Article PDF–3.4M

Select item 546925710.

Virion-Associated Vpr Alleviates a Postintegration Block to HIV-1 Infection of Dendritic Cells

Caitlin M. Miller, Hisashi Akiyama, Luis M. Agosto, Ann Emery, Chelsea R. Ettinger, Ronald I. Swanstrom, Andrew J. Henderson, Suryaram Gummuluru

J Virol. 2017 Jul 1; 91(13): e00051-17. Prepublished online 2017 Apr 19. Published online 2017 Jun 9. doi: 10.1128/JVI.00051-17

PMCID:: PMC5469257

Abstract Article PDF–827K

Select item 395519211.

Lentivirus Vpr and Vpx accessory proteins usurp the cullin4–DDB1 (DCAF1) E3 ubiquitin ligase

Bizhan Romani, Éric A Cohen

Curr Opin Virol. Author manuscript; available in PMC 2014 Mar 15.

Published in final edited form as: Curr Opin Virol. 2012 Dec; 2(6): 755–763. Published online 2012 Oct 10. doi: 10.1016/j.coviro.2012.09.010

PMCID:: PMC3955192

Abstract Article PDF–947K

Select item 385128912.

VprBP Has Intrinsic Kinase Activity Targeting Histone H2A and Represses Gene Transcription

Kyunghwan Kim, Jin-Man Kim, Joong-Sun Kim, Jongkyu Choi, Yong Suk Lee, Nouri Neamati, Jin Sook Song, Kyu Heo, Woojin An

Mol Cell. Author manuscript; available in PMC 2014 Nov 7.

Published in final edited form as: Mol Cell. 2013 Nov 7; 52(3): 10.1016/j.molcel.2013.09.017. Published online 2013 Oct 17. doi: 10.1016/j.molcel.2013.09.017

PMCID:: PMC3851289

Abstract Article PDF–3.1M

Select item 313065513.

Vpx rescues HIV-1 transduction of dendritic cells from the antiviral state established by type 1 interferon

Thomas Pertel, Christian Reinhard, Jeremy Luban

Retrovirology. 2011; 8: 49. Published online 2011 Jun 22. doi: 10.1186/1742-4690-8-49

PMCID:: PMC3130655

Abstract Article PDF–789K

Select item 281231014.

Evidence for an Activation Domain at the Amino Terminus of Simian Immunodeficiency Virus Vpx

Thomas Gramberg, Nicole Sunseri, Nathaniel R. Landau

J Virol. 2010 Feb; 84(3): 1387–1396. Published online 2009 Nov 18. doi: 10.1128/JVI.01437-09

PMCID:: PMC2812310

Abstract Article PDF–1.2M

Select item 927046715.

Stabilization of SAMHD1 by NONO is crucial for Ara-C resistance in AML

Feifei Zhang, Jun Sun, Xiaofeng Tang, Yiping Liang, Quanhui Jiao, Bo Yu, Zhengzai Dai, Xuhui Yuan, Jiayu Li, Jinhua Yan, Zhiping Zhang, Song Fan, Min Wang, Haiyan Hu, Changhua Zhang, Xiao-Bin Lv

Cell Death Dis. 2022 Jul; 13(7): 590. Published online 2022 Jul 8. doi: 10.1038/s41419-022-05023-0

PMCID:: PMC9270467

Abstract Article PDF–3.6M

Select item 445594216.

Determinants for degradation of SAMHD1, Mus81 and induction of G₂ arrest in HIV-1 Vpr and SIVagm Vpr

Ana Beatriz DePaula-Silva, Patrick A. Cassiday, Jeffrey Chumley, Alberto Bosque, Carlos M. R. Monteiro-Filho, Cathal S. Mahon, Kelsey R. Cone, Nevan Krogan, Nels C. Elde, Vicente Planelles

Virology. Author manuscript; available in PMC 2015 Jun 4.

Published in final edited form as: Virology. 2015 Mar; 477: 10–17. Published online 2015 Jan 22. doi: 10.1016/j.virol.2014.12.040