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Select item 64842231.

Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback

Denis Menshykau, Odyssé Michos, Christine Lang, Lisa Conrad, Andrew P. McMahon, Dagmar Iber

Nat Commun. 2019; 10: 239. Published online 2019 Jan 16. doi: 10.1038/s41467-018-08212-8

PMCID:: PMC6484223

Abstract Article PDF–1.9M

Select item 64451272.

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis

Karol Kaiser, Daniel Gyllborg, Jan Procházka, Alena Salašová, Petra Kompaníková, Francisco Lamus Molina, Rocio Laguna-Goya, Tomasz Radaszkiewicz, Jakub Harnoš, Michaela Procházková, David Potěšil, Roger A. Barker, Ángel Gato Casado, Zbyněk Zdráhal, Radislav Sedláček, Ernest Arenas, J. Carlos Villaescusa, Vítězslav Bryja

Nat Commun. 2019; 10: 1498. Published online 2019 Apr 2. doi: 10.1038/s41467-019-09298-4

PMCID:: PMC6445127

Abstract Article PDF–6.0M

Select item 62813193.

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

Lori L O'Brien, Alexander N Combes, Kieran M Short, Nils O Lindström, Peter H Whitney, Luise A Cullen-McEwen, Adler Ju, Ahmed Abdelhalim, Odyssé Michos, John F Bertram, Ian M Smyth, Melissa H Little, Andrew P McMahon

eLife. 2018; 7: e40392. Published online 2018 Dec 5. doi: 10.7554/eLife.40392

PMCID:: PMC6281319

Abstract Article PDF–11M

Select item 60420744.

Wnt/β-catenin signaling regulates ependymal cell development and adult homeostasis

Liujing Xing, Teni Anbarchian, Jonathan M. Tsai, Giles W. Plant, Roeland Nusse

Proc Natl Acad Sci U S A. 2018 Jun 26; 115(26): E5954–E5962. Published online 2018 Jun 11. doi: 10.1073/pnas.1803297115

PMCID:: PMC6042074

Abstract Article PDF–1.9M

Select item 54632655.

Rapamycin efficiently promotes cardiac differentiation of mouse embryonic stem cells

Qin Lu, Yinan Liu, Yang Wang, Weiping Wang, Zhe Yang, Tao Li, Yuyao Tian, Ping Chen, Kangtao Ma, Zhuqing Jia, Chunyan Zhou

Biosci Rep. 2017 Jun 30; 37(3): BSR20160552. Prepublished online 2017 Apr 10. Published online 2017 Jun 7. doi: 10.1042/BSR20160552

PMCID:: PMC5463265

Abstract Article PDF–1.2M

Select item 50106736.

Wnt signaling in regulation of biological functions of the nurse cell harboring Trichinella spp.

Magdalena Dabrowska, Marek Skoneczny, Zbigniew Zielinski, Wojciech Rode

Parasit Vectors. 2016; 9(1): 483. Published online 2016 Sep 2. doi: 10.1186/s13071-016-1770-4

PMCID:: PMC5010673

Abstract Article PDF–1.8M

Select item 49432367.

Fibrosis of the Neonatal Mouse Heart After Cryoinjury Is Accompanied by Wnt Signaling Activation and Epicardial‐to‐Mesenchymal Transition

Makiko Mizutani, Joseph C. Wu, Roeland Nusse

J Am Heart Assoc. 2016 Mar; 5(3): e002457. Published online 2016 Mar 15. doi: 10.1161/JAHA.115.002457

PMCID:: PMC4943236

Abstract Article PDF–4.2M

Select item 49264938.

MicroRNA Expression Profiling in CCl₄-Induced Liver Fibrosis of Mus musculus

Jeongeun Hyun, Jungwook Park, Sihyung Wang, Jieun Kim, Hyun-Hee Lee, Young-Su Seo, Youngmi Jung

Int J Mol Sci. 2016 Jun; 17(6): 961. Published online 2016 Jun 17. doi: 10.3390/ijms17060961

PMCID:: PMC4926493

Abstract Article PDF–7.6M

Select item 48013099.

Paracrine Wnt/β-catenin signaling mediates proliferation of undifferentiated spermatogonia in the adult mouse testis

Hinako M. Takase, Roeland Nusse

Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11): E1489–E1497. Published online 2016 Feb 29. doi: 10.1073/pnas.1601461113

PMCID:: PMC4801309

Abstract Article PDF–2.4M

Select item 426737510.

Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation

Si Hui Tan, Kshemendra Senarath-Yapa, Michael T. Chung, Michael T. Longaker, Joy Y. Wu, Roeland Nusse

Proc Natl Acad Sci U S A. 2014 Dec 9; 111(49): E5262–E5271. Published online 2014 Nov 24. doi: 10.1073/pnas.1420463111

PMCID:: PMC4267375

Abstract Article PDF–3.2M

Select item 423176711.

THOC5 controls 3′end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100)

Doan Duy Hai Tran, Shashank Saran, Andrew J.K. Williamson, Andrew Pierce, Oliver Dittrich-Breiholz, Lutz Wiehlmann, Alexandra Koch, Anthony D. Whetton, Teruko Tamura

Nucleic Acids Res. 2014 Oct 29; 42(19): 12249–12260. Published online 2014 Oct 1. doi: 10.1093/nar/gku911

PMCID:: PMC4231767

Abstract Article PDF–3.4M

Select item 422687412.

Murine precision-cut liver slices (PCLS): a new tool for studying tumor microenvironments and cell signaling ex vivo

Alexandra Koch, Shashank Saran, Doan Duy Hai Tran, Sabine Klebba-Färber, Hauke Thiesler, Katherina Sewald, Susann Schindler, Armin Braun, Robert Klopfleisch, Teruko Tamura

Cell Commun Signal. 2014; 12: 73. Published online 2014 Nov 7. doi: 10.1186/s12964-014-0073-7

PMCID:: PMC4226874

Abstract Article PDF–2.7M

Select item 422258613.

THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier

Shashank Saran, Doan DH Tran, Sabine Klebba-Färber, Patricia Moran-Losada, Lutz Wiehlmann, Alexandra Koch, Himpriya Chopra, Oliver Pabst, Andrea Hoffmann, Robert Klopfleisch, Teruko Tamura

BMC Cell Biol. 2013; 14: 51. Published online 2013 Nov 22. doi: 10.1186/1471-2121-14-51

PMCID:: PMC4222586

Abstract Article PDF–1.7M

Select item 421453514.

Loss of the Podocyte-Expressed Transcription Factor Tcf21/Pod1 Results in Podocyte Differentiation Defects and FSGS

Yoshiro Maezawa, Tuncer Onay, Rizaldy P. Scott, Lindsay S. Keir, Henrik Dimke, Chengjin Li, Vera Eremina, Yuko Maezawa, Marie Jeansson, Jingdong Shan, Matthew Binnie, Moshe Lewin, Asish Ghosh, Jeffrey H. Miner, Seppo J. Vainio, Susan E. Quaggin

J Am Soc Nephrol. 2014 Nov; 25(11): 2459–2470. Published online 2014 Jun 5. doi: 10.1681/ASN.2013121307

PMCID:: PMC4214535

Abstract Article

Select item 370273515.

Spdef Null Mice Lack Conjunctival Goblet Cells and Provide a Model of Dry Eye

Christina K. Marko, Balaraj B. Menon, Gang Chen, Jeffrey A. Whitsett, Hans Clevers, Ilene K. Gipson

Am J Pathol. 2013 Jul; 183(1): 35–48. doi: 10.1016/j.ajpath.2013.03.017

PMCID:: PMC3702735

Abstract Article PDF–2.2M

Select item 362652116.

Targeted Overexpression of TGF-α in the Corneal Epithelium of Adult Transgenic Mice Induces Changes in Anterior Segment Morphology and Activates Noncanonical Wnt Signaling

Yong Yuan, Lung-Kun Yeh, Hongshan Liu, Osamu Yamanaka, William D. Hardie, Winston W.-Y. Kao, Chia-Yang Liu

Invest Ophthalmol Vis Sci. 2013 Mar; 54(3): 1829–1837. Published online 2013 Mar 11. doi: 10.1167/iovs.12-11477

PMCID:: PMC3626521

Abstract Article PDF–511K

Select item 348322317.

Julia A. Taylor, Catherine A. Richter, Atsuko Suzuki, Hajime Watanabe, Taisen Iguchi, Kathryn R. Coser, Toshihiro Shioda, Frederick S. vom Saal

PLoS One. 2012; 7(10): e48311. Published online 2012 Oct 29. doi: 10.1371/journal.pone.0048311

PMCID:: PMC3483223

Abstract Article PDF–2.0M

Select item 336679218.

Advanced Bone Formation in Mice with a Dominant-negative Mutation in the Thyroid Hormone Receptor β Gene due to Activation of Wnt/β-Catenin Protein Signaling

Patrick J. O'Shea, Dong Wook Kim, John G. Logan, Sean Davis, Robert L. Walker, Paul S. Meltzer, Sheue-yann Cheng, Graham R. Williams

J Biol Chem. 2012 May 18; 287(21): 17812–17822. Published online 2012 Mar 22. doi: 10.1074/jbc.M111.311464

PMCID:: PMC3366792

Abstract Article PDF–2.0M

Select item 317629219.

Mutations in Protein-Binding Hot-Spots on the Hub Protein Smad3 Differentially Affect Its Protein Interactions and Smad3-Regulated Gene Expression

Michelle M. Schiro, Sara E. Stauber, Tami L. Peterson, Chateen Krueger, Steven J. Darnell, Kenneth A. Satyshur, Norman R. Drinkwater, Michael A. Newton, F. Michael Hoffmann

PLoS One. 2011; 6(9): e25021. Published online 2011 Sep 19. doi: 10.1371/journal.pone.0025021