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Select item 69595631.

12-h clock regulation of genetic information flow by XBP1s

Yinghong Pan, Heather Ballance, Huan Meng, Naomi Gonzalez, Sam-Moon Kim, Leymaan Abdurehman, Brian York, Xi Chen, Yisrael Schnytzer, Oren Levy, Clifford C. Dacso, Colleen A. McClung, Bert W. O’Malley, Silvia Liu, Bokai Zhu

PLoS Biol. 2020 Jan; 18(1): e3000580. Published online 2020 Jan 14. doi: 10.1371/journal.pbio.3000580

PMCID:: PMC6959563

Abstract Article PDF–8.5M

Select item 67313002.

Phlda3 regulates beta cell survival during stress

Mohammed Bensellam, Jeng Yie Chan, Kailun Lee, Mugdha V. Joglekar, Anandwardhan A. Hardikar, Thomas Loudovaris, Helen E. Thomas, Jean-Christophe Jonas, D. Ross Laybutt

Sci Rep. 2019; 9: 12827. Published online 2019 Sep 6. doi: 10.1038/s41598-019-49289-5

PMCID:: PMC6731300

Abstract Article PDF–3.2M

Select item 66649353.

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

Marciane Milanski, Giovanna Degasperi, Andressa Coope, Joseane Morari, Raphael Denis, Dennys E. Cintra, Daniela M. L. Tsukumo, Gabriel Anhe, Maria E. Amaral, Hilton K. Takahashi, Rui Curi, Helena C. Oliveira, José B. C. Carvalheira, Silvana Bordin, Mário J. Saad, Lício A. Velloso

J Neurosci. 2009 Jan 14; 29(2): 359–370. doi: 10.1523/JNEUROSCI.2760-08.2009

PMCID:: PMC6664935

Abstract Article PDF–820K

Select item 66257224.

XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease

Katarzyna A. Piróg, Ella P. Dennis, Claire L. Hartley, Robert M. Jackson, Jamie Soul, Jean-Marc Schwartz, John F. Bateman, Raymond P. Boot-Handford, Michael D. Briggs

PLoS Genet. 2019 Jul; 15(7): e1008215. Published online 2019 Jul 1. doi: 10.1371/journal.pgen.1008215

PMCID:: PMC6625722

Abstract Article PDF–5.1M

Select item 64169415.

Melatonin receptor depletion suppressed hCG-induced testosterone expression in mouse Leydig cells

Yuan Gao, Xiaochun Wu, Shuqin Zhao, Yujun Zhang, Hailong Ma, Zhen Yang, Wanghao Yang, Chen Zhao, Li Wang, Quanwei Zhang

Cell Mol Biol Lett. 2019; 24: 21. Published online 2019 Mar 12. doi: 10.1186/s11658-019-0147-z

PMCID:: PMC6416941

Abstract Article PDF–1.7M

Select item 63298096.

Metformin prevents cell tumorigenesis through autophagy-related cell death

Mauro De Santi, Giulia Baldelli, Aurora Diotallevi, Luca Galluzzi, Giuditta Fiorella Schiavano, Giorgio Brandi

Sci Rep. 2019; 9: 66. Published online 2019 Jan 11. doi: 10.1038/s41598-018-37247-6

PMCID:: PMC6329809

Abstract Article PDF–3.9M

Select item 62931607.

Glutathione S-transferase P deficiency induces glucose intolerance via JNK-dependent enhancement of hepatic gluconeogenesis

Shubha Ghosh Dastidar, Ganapathy Jagatheesan, Petra Haberzettl, Jasmit Shah, Bradford G. Hill, Aruni Bhatnagar, Daniel J. Conklin

Am J Physiol Endocrinol Metab. 2018 Nov 1; 315(5): E1005–E1018. Published online 2018 Aug 28. doi: 10.1152/ajpendo.00345.2017

PMCID:: PMC6293160

Abstract Article

Select item 61861778.

Critical role of endoplasmic reticulum stress in chronic endothelial activation induced visual deficits in tie2-TNF mice

Raji Lenin, Peter G Nagy, Shanta Alli, Vidhya R Rao, Matthias A Clauss, Uday B. Kompella, Rajashekhar Gangaraju

J Cell Biochem. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: J Cell Biochem. 2018 Nov; 119(10): 8460–8471. Published online 2018 Jul 27. doi: 10.1002/jcb.27072

PMCID:: PMC6186177

Abstract Article PDF–1.7M

Select item 61804069.

Featured Article: Deterioration of visual function mediated by senescence-associated endoplasmic reticulum stress in inflammatory tie2-TNF mice

Raji Lenin, Peter G Nagy, Jordy Gentry, Rajashekhar Gangaraju

Exp Biol Med (Maywood) 2018 Aug; 243(12): 976–984. Published online 2018 Aug 16. doi: 10.1177/1535370218794915

PMCID:: PMC6180406

Abstract Article PDF–742K

Select item 609388310.

The IRE1α-XBP1s pathway promotes insulin-stimulated glucose uptake in adipocytes by increasing PPARγ activity

Yoon Mi Cho, Dong Hee Kim, Kyung Hye Lee, Seong-Whan Jeong, Oh-Joo Kwon

Exp Mol Med. 2018 Aug; 50(8): 102. Published online 2018 Aug 15. doi: 10.1038/s12276-018-0131-0

PMCID:: PMC6093883

Abstract Article PDF–2.7M

Select item 590035811.

NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection

Soo Jung Cho, Kristen Rooney, Augustine M. K. Choi, Heather W. Stout-Delgado

Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1; 314(3): L372–L387. Published online 2017 Nov 2. doi: 10.1152/ajplung.00393.2017

Correction in:: Am J Physiol Lung Cell Mol Physiol. 2020 Dec 1; 319(6): L1063–L1064.

PMCID:: PMC5900358

Abstract Article

Select item 576870212.

The high concentration of progesterone is harmful for endometrial receptivity and decidualization

Yu-Xiang Liang, Li Liu, Zhi-Yong Jin, Xiao-Huan Liang, Yong-Sheng Fu, Xiao-Wei Gu, Zeng-Ming Yang

Sci Rep. 2018; 8: 712. Published online 2018 Jan 15. doi: 10.1038/s41598-017-18643-w

PMCID:: PMC5768702

Abstract Article PDF–5.3M

Select item 574881313.

Spirulina Extract Enhanced a Protective Effect in Type 1 Diabetes by Anti-Apoptosis and Anti-ROS Production

Jiyeong Lee, Arum Park, Mi Jeong Kim, Hee-Joung Lim, Young-Ah Rha, Hee-Gyoo Kang

Nutrients. 2017 Dec; 9(12): 1363. Published online 2017 Dec 15. doi: 10.3390/nu9121363

PMCID:: PMC5748813

Abstract Article PDF–5.4M

Select item 571088314.

The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity

Consuelo Amantini, Valerio Farfariello, Claudio Cardinali, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Laura Bonfili, Valentina Cecarini, Anna Maria Eleuteri, Giorgio Santoni

Oncotarget. 2017 Oct 31; 8(53): 90766–90780. Published online 2017 Oct 11. doi: 10.18632/oncotarget.21798