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Select item 67999381.

Determinants of drug entry into the developing brain

Liam Koehn, Mark Habgood, Yifan Huang, Katarzyna Dziegielewska, Norman Saunders

Version 1. F1000Res. 2019; 8: 1372. Published online 2019 Aug 7. doi: 10.12688/f1000research.20078.1

PMCID:: PMC6799938

Abstract Article PDF–2.1M

Select item 65237792.

Functional Characterization of Clinically-Relevant Rare Variants in ABCG2 Identified in a Gout and Hyperuricemia Cohort

Yu Toyoda, Andrea Mančíková, Vladimír Krylov, Keito Morimoto, Kateřina Pavelcová, Jana Bohatá, Karel Pavelka, Markéta Pavlíková, Hiroshi Suzuki, Hirotaka Matsuo, Tappei Takada, Blanka Stiburkova

Cells. 2019 Apr; 8(4): 363. Published online 2019 Apr 18. doi: 10.3390/cells8040363

PMCID:: PMC6523779

Abstract Article PDF–1.8M

Select item 64616373.

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide

Liam M. Koehn, Katarzyna M. Dziegielewska, Kjeld Møllgård, Elodie Saudrais, Nathalie Strazielle, Jean-Francois Ghersi-Egea, Norman R. Saunders, Mark D. Habgood

Sci Rep. 2019; 9: 5998. Published online 2019 Apr 12. doi: 10.1038/s41598-019-42402-8

PMCID:: PMC6461637

Abstract Article PDF–2.0M

Select item 64478244.

Electrospun gelatin/PCL and collagen/PCL scaffolds for modulating responses of bone marrow endothelial progenitor cells

Yang Hu, Bei Feng, Weijie Zhang, Chenxi Yan, Qinke Yao, Chunyi Shao, Fei Yu, Fen Li, Yao Fu

Exp Ther Med. 2019 May; 17(5): 3717–3726. Published online 2019 Mar 13. doi: 10.3892/etm.2019.7387

PMCID:: PMC6447824

Abstract Article PDF–1.6M

Select item 63790615.

Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states

Ioannis Manolaridis, Scott M. Jackson, Nicholas M. I. Taylor, Julia Kowal, Henning Stahlberg, Kaspar P. Locher

Nature. Author manuscript; available in PMC 2019 May 7.

Published in final edited form as: Nature. 2018 Nov; 563(7731): 426–430. Published online 2018 Nov 7. doi: 10.1038/s41586-018-0680-3

PMCID:: PMC6379061

Abstract Article PDF–4.4M

Select item 61053906.

Dietary fat and fiber interact to uniquely modify global histone post-translational epigenetic programming in a rat colon cancer progression model

Karen Triff, Mathew W. McLean, Evelyn Callaway, Jennifer Goldsby, Ivan Ivanov, Robert S. Chapkin

Int J Cancer. Author manuscript; available in PMC 2019 Sep 15.

Published in final edited form as: Int J Cancer. 2018 Sep 15; 143(6): 1402–1415. Published online 2018 May 10. doi: 10.1002/ijc.31525

PMCID:: PMC6105390

Abstract Article PDF–2.4M

Select item 61027477.

Quercetin-3-O-β-D-glucoside decreases the bioavailability of cyclosporin A through regulation of drug metabolizing enzymes, transporters and nuclear receptors in rats

Tingyu Yang, Yani Liu, Xixi Huang, Rui Zhang, Chunxiao Yang, Jiali Zhou, Yu Zhang, Jing Wan, Shaojun Shi

Mol Med Rep. 2018 Sep; 18(3): 2599–2612. Published online 2018 Jul 3. doi: 10.3892/mmr.2018.9249

PMCID:: PMC6102747

Abstract Article PDF–1.1M

Select item 59747208.

Urate transport function of rat sodium‐dependent nucleobase transporter 1

Tomoya Yasujima, Chihiro Murata, Yoshihisa Mimura, Tomoaki Murata, Masahiko Ohkubo, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa

Physiol Rep. 2018 May; 6(10): e13714. Published online 2018 May 20. doi: 10.14814/phy2.13714

PMCID:: PMC5974720

Abstract Article PDF–460K

Select item 54977569.

Localization of the Placental BCRP/ABCG2 Transporter to Lipid Rafts: Role for Cholesterol in Mediating Efflux Activity

John T. Szilagyi, Anna M. Vetrano, Jeffrey D. Laskin, Lauren M. Aleksunes

Placenta. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Placenta. 2017 Jul; 55: 29–36. Published online 2017 Apr 12. doi: 10.1016/j.placenta.2017.04.006

PMCID:: PMC5497756

Abstract Article PDF–1.3M

Select item 547020410.

Cichorium intybus L. promotes intestinal uric acid excretion by modulating ABCG2 in experimental hyperuricemia

Yu Wang, Zhijian Lin, Bing Zhang, Anzheng Nie, Meng Bian

Nutr Metab (Lond) 2017; 14: 38. Published online 2017 Jun 13. doi: 10.1186/s12986-017-0190-6

Correction in:: Nutr Metab (Lond). 2021; 18: 109.

PMCID:: PMC5470204

Abstract Article PDF–1.0M

Select item 504275111.

Impact of quercetin-induced changes in drug-metabolizing enzyme and transporter expression on the pharmacokinetics of cyclosporine in rats

Yani Liu, Xiaomei Luo, Chunxiao Yang, Tingyu Yang, Jiali Zhou, Shaojun Shi

Mol Med Rep. 2016 Oct; 14(4): 3073–3085. Published online 2016 Aug 9. doi: 10.3892/mmr.2016.5616

PMCID:: PMC5042751

Abstract Article PDF–872K

Select item 504140112.

Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats

Haiyan Zhang, Wen-Jun Shen, Yihang Li, Alex Bittner, Stefanie Bittner, Juveria Tabassum, Yuan F. Cortez, Fredric B. Kraemer, Salman Azhar

Nutr Metab (Lond) 2016; 13: 63. Published online 2016 Sep 29. doi: 10.1186/s12986-016-0121-y

PMCID:: PMC5041401

Abstract Article PDF–2.9M

Select item 489525913.

Genome-wide transcriptome analysis of hypothalamus in rats with inherited stress-induced arterial hypertension

Leonid O. Klimov, Nikita I. Ershov, Vadim M. Efimov, Arcady L. Markel, Olga E. Redina

BMC Genet. 2016; 17(Suppl 1): 13. Published online 2016 Jan 27. doi: 10.1186/s12863-015-0307-8

PMCID:: PMC4895259

Abstract Article PDF–1.0M

Select item 477585114.

Inhibition of hepatic cytochrome P450 enzymes and sodium/bile acid cotransporter exacerbates leflunomide-induced hepatotoxicity

Lei-lei Ma, Zhi-tao Wu, Le Wang, Xue-feng Zhang, Jing Wang, Chen Chen, Xuan Ni, Yun-fei Lin, Yi-yi Cao, Yang Luan, Guo-yu Pan

Acta Pharmacol Sin. 2016 Mar; 37(3): 415–424. Published online 2016 Jan 25. doi: 10.1038/aps.2015.157

PMCID:: PMC4775851

Abstract Article PDF–1.2M

Select item 452712815.

Transfection of brain capillary endothelial cells in primary culture with defined blood–brain barrier properties

Annette Burkhart, Louiza Bohn Thomsen, Maj Schneider Thomsen, Jacek Lichota, Csilla Fazakas, István Krizbai, Torben Moos

Fluids Barriers CNS. 2015; 12: 19. Published online 2015 Aug 7. doi: 10.1186/s12987-015-0015-9

PMCID:: PMC4527128

Abstract Article PDF–4.2M

Select item 440274516.

Oral administration of oleanolic acid, isolated from Swertia mussotii Franch, attenuates liver injury, inflammation, and cholestasis in bile duct-ligated rats

Jin Chai, Xiaohuang Du, Sheng Chen, XinChan Feng, Ying Cheng, Liangjun Zhang, Yu Gao, Shaoxue Li, Xiaochong He, Rongquan Wang, Xiangdong Zhou, Yong Yang, Weizao Luo, Wensheng Chen

Int J Clin Exp Med. 2015; 8(2): 1691–1702. Published online 2015 Feb 15.

PMCID:: PMC4402745

Abstract Article PDF–2.0M

Select item 434889617.

Swertianlarin, isolated from Swertia mussotii Franch, increases detoxification enzymes and efflux transporters expression in rats

Xin-Chan Feng, Xiaohuang Du, Sheng Chen, Dongmei Yue, Ying Cheng, Liangjun Zhang, Yu Gao, Shaoxue Li, Lei Chen, Zhihong Peng, Yong Yang, Weizao Luo, Rongquan Wang, Wensheng Chen, Jin Chai

Int J Clin Exp Pathol. 2015; 8(1): 184–195. Published online 2015 Jan 1.

PMCID:: PMC4348896

Abstract Article PDF–1.7M

Select item 416751018.

microRNA alterations in ALDH positive mammary epithelial cells: a crucial contributing factor towards breast cancer risk reduction in case of early pregnancy

Sushmita Bose Nandy, Ramadevi Subramani, Venkatesh Rajamanickam, Rebecca Lopez-Valdez, Arunkumar Arumugam, Thiyagarajan Boopalan, Rajkumar Lakshmanaswamy

BMC Cancer. 2014; 14: 644. Published online 2014 Aug 31. doi: 10.1186/1471-2407-14-644