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Items: 12

Select item 63079461.

TNF/TNFR axis promotes pyrin inflammasome activation and distinctly modulates pyrin inflammasomopathy

Deepika Sharma, Ankit Malik, Clifford Guy, Peter Vogel, Thirumala-Devi Kanneganti

J Clin Invest. 2019 Jan 2; 129(1): 150–162. Published online 2018 Nov 19. doi: 10.1172/JCI121372

PMCID:: PMC6307946

Abstract Article PDF–13M

Select item 62429542.

Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis

Pedro H. V. Saavedra, Linyan Huang, Farzaneh Ghazavi, Stephanie Kourula, Tom Vanden Berghe, Nozomi Takahashi, Peter Vandenabeele, Mohamed Lamkanfi

Nat Commun. 2018; 9: 4846. Published online 2018 Nov 19. doi: 10.1038/s41467-018-07386-5

PMCID:: PMC6242954

Abstract Article PDF–1.5M

Select item 59355773.

IRF8 regulates transcription of Naips for NLRC4 inflammasome activation

Rajendra Karki, Ein Lee, David Place, Parimal Samir, Jayadev Mavuluri, Bhesh Raj Sharma, Arjun Balakrishnan, R. K. Subbarao Malireddi, Rechel Geiger, Qifan Zhu, Geoffrey Neale, Thirumala-Devi Kanneganti

Cell. Author manuscript; available in PMC 2019 May 3.

Published in final edited form as: Cell. 2018 May 3; 173(4): 920–933.e13. Published online 2018 Mar 22. doi: 10.1016/j.cell.2018.02.055

PMCID:: PMC5935577

Abstract Article PDF–2.0M

Select item 58474564.

Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis

Deepika Sharma, Ankit Malik, Clifford S. Guy, Rajendra Karki, Peter Vogel, Thirumala-Devi Kanneganti

Gastroenterology. Author manuscript; available in PMC 2019 Mar 1.

Published in final edited form as: Gastroenterology. 2018 Mar; 154(4): 948–964.e8. Published online 2017 Dec 2. doi: 10.1053/j.gastro.2017.11.276

PMCID:: PMC5847456

Abstract Article PDF–1.2M

Select item 53893725.

IL-1β and Caspase-1 Drive Autoinflammatory Disease Independently of IL-1α or Caspase-8 in a Mouse Model of Familial Mediterranean Fever

Deepika Sharma, Bhesh Raj Sharma, Peter Vogel, Thirumala-Devi Kanneganti

Am J Pathol. 2017 Feb; 187(2): 236–244. doi: 10.1016/j.ajpath.2016.10.015

PMCID:: PMC5389372

Abstract Article PDF–1.7M

Select item 50253866.

The Yersinia Virulence Factor YopM Hijacks Host Kinases to Inhibit Type III Effector-Triggered Activation of the Pyrin Inflammasome

Lawton K. Chung, Yong Hwan Park, Yueting Zheng, Igor E. Brodsky, Patrick Hearing, Daniel L. Kastner, Jae Jin Chae, James B. Bliska

Cell Host Microbe. Author manuscript; available in PMC 2017 Sep 14.

Published in final edited form as: Cell Host Microbe. 2016 Sep 14; 20(3): 296–306. Published online 2016 Aug 25. doi: 10.1016/j.chom.2016.07.018

PMCID:: PMC5025386

Abstract Article PDF–1.1M

Select item 49959717.

Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation

Wenqing Gao, Jieling Yang, Wang Liu, Yupeng Wang, Feng Shao

Proc Natl Acad Sci U S A. 2016 Aug 16; 113(33): E4857–E4866. Published online 2016 Aug 1. doi: 10.1073/pnas.1601700113

PMCID:: PMC4995971

Abstract Article PDF–1.5M

Select item 36481988.

Venezuelan Equine Encephalitis Replicon Particles Can Induce Rapid Protection against Foot-and-Mouth Disease Virus

Fayna Diaz-San Segundo, Camila C. A. Dias, Mauro P. Moraes, Marcelo Weiss, Eva Perez-Martin, Gary Owens, Max Custer, Kurt Kamrud, Teresa de los Santos, Marvin J. Grubman

J Virol. 2013 May; 87(10): 5447–5460. doi: 10.1128/JVI.03462-12