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Items: 15

Select item 65447631.

Generation of a fully erythromycin-sensitive strain of Clostridioides difficile using a novel CRISPR-Cas9 genome editing system

Patrick Ingle, Daphne Groothuis, Peter Rowe, He Huang, Alan Cockayne, Sarah A. Kuehne, Weihong Jiang, Yang Gu, Christopher M. Humphreys, Nigel P. Minton

Sci Rep. 2019; 9: 8123. Published online 2019 May 31. doi: 10.1038/s41598-019-44458-y

PMCID:: PMC6544763

Abstract Article PDF–2.1M

Select item 64598992.

Pleiotropic Clostridioides difficile Cyclophilin PpiB Controls Cysteine-Tolerance, Toxin Production, the Central Metabolism and Multiple Stress Responses

Can Murat Ünal, Mustafa Safa Karagöz, Mareike Berges, Christina Priebe, José Manuel Borrero de Acuña, Josef Wissing, Lothar Jänsch, Dieter Jahn, Michael Steinert

Front Pharmacol. 2019; 10: 340. Published online 2019 Apr 5. doi: 10.3389/fphar.2019.00340

PMCID:: PMC6459899

Abstract Article PDF–4.2M

Select item 63555843.

Genome Location Dictates the Transcriptional Response to PolC Inhibition in Clostridium difficile

Erika van Eijk, Ilse M. Boekhoud, Ed J. Kuijper, Ingrid M. J. G. Bos-Sanders, George Wright, Wiep Klaas Smits

Antimicrob Agents Chemother. 2019 Feb; 63(2): e01363-18. Prepublished online 2018 Nov 19. Published online 2019 Jan 29. doi: 10.1128/AAC.01363-18

PMCID:: PMC6355584

Abstract Article PDF–1.6M

Select item 62914854.

Genomic Study of a Clostridium difficile Multidrug Resistant Outbreak-Related Clone Reveals Novel Determinants of Resistance

Joana Isidro, Juliana Menezes, Mónica Serrano, Vítor Borges, Pedro Paixão, Margarida Mimoso, Filomena Martins, Cristina Toscano, Andrea Santos, Adriano O. Henriques, Mónica Oleastro

Front Microbiol. 2018; 9: 2994. Published online 2018 Dec 6. doi: 10.3389/fmicb.2018.02994

PMCID:: PMC6291485

Abstract Article PDF–401K

Select item 62885195.

PrsA2 (CD630_35000) of Clostridioides difficile Is an Active Parvulin-Type PPIase and a Virulence Modulator

Can Murat Ünal, Mareike Berges, Nathiana Smit, Cordelia Schiene-Fischer, Christina Priebe, Till Strowig, Dieter Jahn, Michael Steinert

Front Microbiol. 2018; 9: 2913. Published online 2018 Dec 4. doi: 10.3389/fmicb.2018.02913

PMCID:: PMC6288519

Abstract Article PDF–3.0M

Select item 59114086.

Comparative genomics analysis of Clostridium difficile epidemic strain DH/NAP11/106

Larry K. Kociolek, Dale N. Gerding, David W. Hecht, Egon A. Ozer

Microbes Infect. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Microbes Infect. 2018 Apr; 20(4): 245–253. Published online 2018 Jan 31. doi: 10.1016/j.micinf.2018.01.004

PMCID:: PMC5911408

Abstract Article PDF–1.3M

Select item 57866877.

Complete Genome Sequences of Four Toxigenic Clostridium difficile Clinical Isolates from Patients of the Lower Hudson Valley, New York, USA

Changhong Yin, Donald S. Chen, Jian Zhuge, Donna McKenna, Joan Sagurton, Guiqing Wang, Weihua Huang, Nevenka Dimitrova, John T. Fallon

Genome Announc. 2018 Jan; 6(4): e01537-17. Published online 2018 Jan 25. doi: 10.1128/genomeA.01537-17

PMCID:: PMC5786687

Abstract Article PDF–125K

Select item 57490298.

Comparative genome and phenotypic analysis of three Clostridioides difficile strains isolated from a single patient provide insight into multiple infection of C. difficile

Uwe Groß, Elzbieta Brzuszkiewicz, Katrin Gunka, Jessica Starke, Thomas Riedel, Boyke Bunk, Cathrin Spröer, Daniela Wetzel, Anja Poehlein, Cynthia Chibani, Wolfgang Bohne, Jörg Overmann, Ortrud Zimmermann, Rolf Daniel, Heiko Liesegang

BMC Genomics. 2018; 19: 1. Published online 2018 Jan 2. doi: 10.1186/s12864-017-4368-0