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Items: 19

1.
Leucine-Rich Repeat Kinase 2 Is Associated With Activation of the Paraventricular Nucleus of the Hypothalamus and Stress-Related Gastrointestinal Dysmotility
Tatsunori Maekawa, Hiromichi Tsushima, Fumitaka Kawakami, Rei Kawashima, Masaru Kodo, Motoki Imai, Takafumi Ichikawa
Front Neurosci. 2019; 13: 905. Published online 2019 Aug 29. doi: 10.3389/fnins.2019.00905
PMCID:
PMC6727664
AbstractArticlePDF–2.2M
2.
Possible epigenetic regulatory effect of dysregulated circular RNAs in Alzheimer’s disease model
Woo-Jin Lee, Jangsup Moon, Daejong Jeon, Yong-Won Shin, Jung-Suk Yoo, Dong-Kyu Park, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Ki-Young Jung, Manho Kim, Sang Kun Lee, Kon Chu
Sci Rep. 2019; 9: 11956. Published online 2019 Aug 16. doi: 10.1038/s41598-019-48471-z
PMCID:
PMC6697677
AbstractArticlePDF–2.0M
3.
Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes
Jee Hoon Lee, Ji-hye Han, Hyunmi Kim, Sang Myun Park, Eun-hye Joe, Ilo Jou
Acta Neuropathol Commun. 2019; 7: 68. Published online 2019 May 2. doi: 10.1186/s40478-019-0716-4
PMCID:
PMC6498585
AbstractArticlePDF–6.9M
4.
Brain injury induces HIF-1α-dependent transcriptional activation of LRRK2 that exacerbates brain damage
Yun-Hee Bae, Hyejin Joo, Jinhyun Bae, Seung Jae Hyeon, Song Her, Eunhwa Ko, Hwan Geun Choi, Hoon Ryu, Eun-Mi Hur, Youngmin Bu, Byoung Dae Lee
Cell Death Dis. 2018 Nov; 9(11): 1125. Published online 2018 Nov 12. doi: 10.1038/s41419-018-1180-y
PMCID:
PMC6232134
AbstractArticlePDF–4.0M
5.
A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain
Herschel S Dhekne, Izumi Yanatori, Rachel C Gomez, Francesca Tonelli, Federico Diez, Birgitt Schüle, Martin Steger, Dario R Alessi, Suzanne R Pfeffer
eLife. 2018; 7: e40202. Published online 2018 Nov 6. doi: 10.7554/eLife.40202
PMCID:
PMC6219843
AbstractArticlePDF–5.5M
6.
Leucine-Rich Repeat Kinase 2 Controls the Ca2+/Nuclear Factor of Activated T Cells/IL-2 Pathway during Aspergillus Non-Canonical Autophagy in Dendritic Cells
Alicia Yoke Wei Wong, Vasilis Oikonomou, Giuseppe Paolicelli, Antonella De Luca, Marilena Pariano, Jan Fric, Hock Soon Tay, Paola Ricciardi-Castagnoli, Teresa Zelante
Front Immunol. 2018; 9: 210. Published online 2018 Feb 8. doi: 10.3389/fimmu.2018.00210
PMCID:
PMC5809498
AbstractArticlePDF–3.8M
7.
The Receptor-interacting Serine/Threonine Protein Kinase 1 (RIPK1) Regulates Progranulin Levels
Amanda R. Mason, Lisa P. Elia, Steven Finkbeiner
J Biol Chem. 2017 Feb 24; 292(8): 3262–3272. Published online 2017 Jan 9. doi: 10.1074/jbc.M116.752006
PMCID:
PMC5336161
AbstractArticlePDF–1.1M
8.
Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors
Genta Ito, Kristina Katsemonova, Francesca Tonelli, Pawel Lis, Marco A.S. Baptista, Natalia Shpiro, Graham Duddy, Steve Wilson, Philip Wing-Lok Ho, Shu-Leong Ho, Alastair D. Reith, Dario R. Alessi
Biochem J. 2016 Sep 1; 473(17): 2671–2685. Published online 2016 Aug 30. doi: 10.1042/BCJ20160557
PMCID:
PMC5003698
AbstractArticlePDF–1.3M
9.
Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice
Dayne A. Beccano-Kelly, Naila Kuhlmann, Igor Tatarnikov, Mattia Volta, Lise N. Munsie, Patrick Chou, Li-Ping Cao, Heather Han, Lucia Tapia, Matthew J. Farrer, Austen J. Milnerwood
Front Cell Neurosci. 2014; 8: 301. Published online 2014 Sep 26. doi: 10.3389/fncel.2014.00301
PMCID:
PMC4176085
AbstractArticlePDF–3.8M
10.
CONSEQUENCES OF IMPAIRED PURINE RECYCLING IN DOPAMINERGIC NEURONS
J. C. Lewers, I. Ceballos-Picot, T. L. Shirley, L. Mockel, K. Egami, H. A. Jinnah
Neuroscience. Author manuscript; available in PMC 2012 Nov 15.
Published in final edited form as: Neuroscience. 2008 Mar 27; 152(3): 761–772. Published online 2008 Jan 17. doi: 10.1016/j.neuroscience.2007.10.065
PMCID:
PMC3498629
AbstractArticlePDF–2.8M
11.
Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia
Beomsue Kim, Myung-Soon Yang, Dongjoo Choi, Jong-Hyeon Kim, Hye-Sun Kim, Wongi Seol, Sangdun Choi, Ilo Jou, Eun-Young Kim, Eun-hye Joe
PLoS One. 2012; 7(4): e34693. Published online 2012 Apr 9. doi: 10.1371/journal.pone.0034693
PMCID:
PMC3322140
AbstractArticlePDF–1.1M
12.
Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity
Elena V. Nikonova, Yulan Xiong, Keith Q. Tanis, Valina L. Dawson, Robert L. Vogel, Eva M. Finney, David J. Stone, Ian J. Reynolds, Jonathan T. Kern, Ted M. Dawson
Hum Mol Genet. 2012 Jan 1; 21(1): 163–174. Published online 2011 Oct 4. doi: 10.1093/hmg/ddr451
PMCID:
PMC3235012
AbstractArticlePDF–431K
13.
A QUICK Screen for Lrrk2 Interaction Partners – Leucine-rich Repeat Kinase 2 is Involved in Actin Cytoskeleton Dynamics
Andrea Meixner, Karsten Boldt, Marleen Van Troys, Manor Askenazi, Christian J. Gloeckner, Matthias Bauer, Jarrod A. Marto, Christophe Ampe, Norbert Kinkl, Marius Ueffing
Mol Cell Proteomics. 2011 Jan; 10(1): M110.001172. Published online 2010 Sep 27. doi: 10.1074/mcp.M110.001172
PMCID:
PMC3013447
AbstractArticlePDF–958K
14.
Identification of Host-Dependent Survival Factors for Intracellular Mycobacterium tuberculosis through an siRNA Screen
Shilpi Jayaswal, Md. Azhar Kamal, Raina Dua, Shashank Gupta, Tanmay Majumdar, Gobardhan Das, Dhiraj Kumar, Kanury V. S. Rao
PLoS Pathog. 2010 Apr; 6(4): e1000839. Published online 2010 Apr 15. doi: 10.1371/journal.ppat.1000839
PMCID:
PMC2855445
AbstractArticlePDF–1.1M
15.
Misexpression of MIA Disrupts Lung Morphogenesis and Causes Neonatal Death
Sui Lin, Machiko Ikegami, Yan Xu, Anja-Katrin Bosserhoff, Alvin M. Malkinson, John M. Shannon
Dev Biol. Author manuscript; available in PMC 2009 Apr 15.
Published in final edited form as: Dev Biol. 2008 Apr 15; 316(2): 441–455. Published online 2008 Feb 15. doi: 10.1016/j.ydbio.2008.02.003
PMCID:
PMC2362150
AbstractArticlePDF–5.0M
16.
Dynamic and redundant regulation of LRRK2 and LRRK1 expression
Saskia Biskup, Darren J Moore, Alexis Rea, Bettina Lorenz-Deperieux, Candice E Coombes, Valina L Dawson, Ted M Dawson, Andrew B West
BMC Neurosci. 2007; 8: 102. Published online 2007 Nov 28. doi: 10.1186/1471-2202-8-102
PMCID:
PMC2233633
AbstractArticlePDF–534K
17.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
18.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
19.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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