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Select item 81755821.

FBXO15 plays a critical suppressive functional role in regulation of breast cancer progression

Yi Zhao, Nayeon Shim, Yan-Hong Cui, Jae-Hyeok Kang, Ki-Chun Yoo, Seungmo Kim, Joo Mi Yi, Min-Jung Kim, Jai Hoon Yoon, Su-Jae Lee

Signal Transduct Target Ther. 2021; 6: 211. Published online 2021 Jun 4. doi: 10.1038/s41392-021-00605-4

PMCID:: PMC8175582

Article PDF–1.5M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76571323.

FBXO15 regulates P‐glycoprotein/ABCB1 expression through the ubiquitin–proteasome pathway in cancer cells

Kazuhiro Katayama, Kohji Noguchi, Yoshikazu Sugimoto

Cancer Sci. 2013 Jun; 104(6): 694–702. Published online 2013 Apr 15. doi: 10.1111/cas.12145

PMCID:: PMC7657132

Abstract Article PDF–1.2M

Select item 65884664.

Cyclin F controls cell cycle transcriptional outputs by directing the degradation of the three activator E2Fs

Linda Clijsters, Claire Hoencamp, Jorg J. A. Calis, Antonio Marzio, Shanna M. Handgraaf, Maria C. Cuitino, Brad R. Rosenberg, Gustavo Leone, Michele Pagano

Mol Cell. Author manuscript; available in PMC 2020 Jun 20.

Published in final edited form as: Mol Cell. 2019 Jun 20; 74(6): 1264–1277.e7. Published online 2019 May 23. doi: 10.1016/j.molcel.2019.04.010

PMCID:: PMC6588466

Abstract Article PDF–2.7M

Select item 63511065.

The ULK1-FBXW5-SEC23B nexus controls autophagy

Yeon-Tae Jeong, Daniele Simoneschi, Sarah Keegan, David Melville, Natalia S Adler, Anita Saraf, Laurence Florens, Michael P Washburn, Claudio N Cavasotto, David Fenyö, Ana Maria Cuervo, Mario Rossi, Michele Pagano

eLife. 2018; 7: e42253. Published online 2018 Dec 31. doi: 10.7554/eLife.42253

PMCID:: PMC6351106

Abstract Article PDF–4.4M

Select item 61666826.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 46479418.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Abstract Article

Select item 46172119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 408568310.

E3 Ligase Subunit Fbxo15 and PINK1 Kinase Regulate Cardiolipin Synthase 1 Stability and Mitochondrial Function in Pneumonia

Bill B. Chen, Tiffany A. Coon, Jennifer R. Glasser, Chunbin Zou, Bryon Ellis, Tuhin Das, Alison C. McKelvey, Shristi Rajbhandari, Travis Lear, Christelle Kamga, Sruti Shiva, Chenjian Li, Joseph M. Pilewski, Jason Callio, Charleen T. Chu, Anuradha Ray, Prabir Ray, Yulia Y. Tyurina, Valerian E. Kagan, Rama K. Mallampalli

Cell Rep. Author manuscript; available in PMC 2015 Apr 24.

Published in final edited form as: Cell Rep. 2014 Apr 24; 7(2): 476–487. Published online 2014 Apr 3. doi: 10.1016/j.celrep.2014.02.048

PMCID:: PMC4085683

Abstract Article PDF–1.8M

Select item 408345811.

A Genome-Wide Association Study of Sleep Habits and Insomnia

Enda M Byrne, Philip R Gehrman, Sarah E Medland, Dale R Nyholt, Andrew C Heath, Pamela AF Madden, The Chronogen Consortium, Ian B Hickie, Cornelia M Van Duijn, Anjali K Henders, Grant W Montgomery, Nicholas G Martin, Naomi R Wray

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2014 Jul 7.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2013 Jul; 0(5): 439–451. Published online 2013 May 31. doi: 10.1002/ajmg.b.32168

PMCID:: PMC4083458

Abstract Article PDF–123K

Select item 404386812.

Genome-wide association study of primary dentition pit-and-fissure and smooth surface caries

Zhen Zeng, Eleanor Feingold, Xiaojing Wang, Daniel E. Weeks, Myoungkeun Lee, Karen T. Cuenco, Barbara Broffitt, Robert J. Weyant, Richard Crout, Daniel W. McNeil, Steven M. Levy, Mary L. Marazita, John. R. Shaffer

Caries Res. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Caries Res. 2014; 48(4): 330–338. doi: 10.1159/000356299

PMCID:: PMC4043868

Abstract Article PDF–225K

Select item 386025813.

Gene-alcohol interactions identify several novel blood pressure loci including a promising locus near SLC16A9

Jeannette Simino, Yun Ju Sung, Rezart Kume, Karen Schwander, D. C. Rao

Front Genet. 2013; 4: 277. Published online 2013 Dec 12. doi: 10.3389/fgene.2013.00277

PMCID:: PMC3860258

Abstract Article PDF–2.9M

Select item 373359514.

Genetics of coronary artery calcification among African Americans, a meta-analysis

Mary K Wojczynski, Mingyao Li, Lawrence F Bielak, Kathleen F Kerr, Alex P Reiner, Nathan D Wong, Lisa R Yanek, Liming Qu, Charles C White, Leslie A Lange, Jane F Ferguson, Jing He, Taylor Young, Thomas H Mosley, Jennifer A Smith, Brian G Kral, Xiuqing Guo, Quenna Wong, Santhi K Ganesh, Susan R Heckbert, Michael E Griswold, Daniel H O’Leary, Matthew Budoff, J Jeffrey Carr, Herman A Taylor,, Jr., David A Bluemke, Serkalem Demissie, Shih-Jen Hwang, Dina N Paltoo, Joseph F Polak, Bruce M Psaty, Diane M Becker, Michael A Province, Wendy S Post, Christopher J O’Donnell, James G Wilson, Tamara B Harris, Maryam Kavousi, L Adrienne Cupples, Jerome I Rotter, Myriam Fornage, Lewis C Becker, Patricia A Peyser, Ingrid B Borecki, Muredach P Reilly

BMC Med Genet. 2013; 14: 75. Published online 2013 Jul 19. doi: 10.1186/1471-2350-14-75

PMCID:: PMC3733595

Abstract Article PDF–884K

Select item 360788615.

A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis

Nicolas Greliche, Marine Germain, Jean-Charles Lambert, William Cohen, Marion Bertrand, Anne-Marie Dupuis, Luc Letenneur, Mark Lathrop, Philippe Amouyel, Pierre-Emmanuel Morange, David-Alexandre Trégouët

BMC Med Genet. 2013; 14: 36. Published online 2013 Mar 20. doi: 10.1186/1471-2350-14-36

PMCID:: PMC3607886

Abstract Article PDF–191K

Select item 356717516.

A Meta-Analysis of Thyroid-Related Traits Reveals Novel Loci and Gender-Specific Differences in the Regulation of Thyroid Function

Eleonora Porcu, Marco Medici, Giorgio Pistis, Claudia B. Volpato, Scott G. Wilson, Anne R. Cappola, Steffan D. Bos, Joris Deelen, Martin den Heijer, Rachel M. Freathy, Jari Lahti, Chunyu Liu, Lorna M. Lopez, Ilja M. Nolte, Jeffrey R. O'Connell, Toshiko Tanaka, Stella Trompet, Alice Arnold, Stefania Bandinelli, Marian Beekman, Stefan Böhringer, Suzanne J. Brown, Brendan M. Buckley, Clara Camaschella, Anton J. M. de Craen, Gail Davies, Marieke C. H. de Visser, Ian Ford, Tom Forsen, Timothy M. Frayling, Laura Fugazzola, Martin Gögele, Andrew T. Hattersley, Ad R. Hermus, Albert Hofman, Jeanine J. Houwing-Duistermaat, Richard A. Jensen, Eero Kajantie, Margreet Kloppenburg, Ee M. Lim, Corrado Masciullo, Stefano Mariotti, Cosetta Minelli, Braxton D. Mitchell, Ramaiah Nagaraja, Romana T. Netea-Maier, Aarno Palotie, Luca Persani, Maria G. Piras, Bruce M. Psaty, Katri Räikkönen, J. Brent Richards, Fernando Rivadeneira, Cinzia Sala, Mona M. Sabra, Naveed Sattar, Beverley M. Shields, Nicole Soranzo, John M. Starr, David J. Stott, Fred C. G. J. Sweep, Gianluca Usala, Melanie M. van der Klauw, Diana van Heemst, Alies van Mullem, Sita H.Vermeulen, W. Edward Visser, John P. Walsh, Rudi G. J. Westendorp, Elisabeth Widen, Guangju Zhai, Francesco Cucca, Ian J. Deary, Johan G. Eriksson, Luigi Ferrucci, Caroline S. Fox, J. Wouter Jukema, Lambertus A. Kiemeney, Peter P. Pramstaller, David Schlessinger, Alan R. Shuldiner, Eline P. Slagboom, André G. Uitterlinden, Bijay Vaidya, Theo J. Visser, Bruce H. R. Wolffenbuttel, Ingrid Meulenbelt, Jerome I. Rotter, Tim D. Spector, Andrew A. Hicks, Daniela Toniolo, Serena Sanna, Robin P. Peeters, Silvia Naitza

PLoS Genet. 2013 Feb; 9(2): e1003266. Published online 2013 Feb 7. doi: 10.1371/journal.pgen.1003266