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Select item 97979881.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 95973522.

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes

Shalini Rawat, Dhruba Chatterjee, Rituraj Marwaha, Gitanjali Charak, Gaurav Kumar, Shrestha Shaw, Divya Khatter, Sheetal Sharma, Cecilia de Heus, Nalan Liv, Judith Klumperman, Amit Tuli, Mahak Sharma

J Cell Biol. 2023 Jan 2; 222(1): e202108001. Published online 2022 Oct 25. doi: 10.1083/jcb.202108001

PMCID:: PMC9597352

Abstract Article PDF–12M

Select item 95253413.

Heat-shock protein 90α is a potential prognostic and predictive biomarker in hepatocellular carcinoma: a large-scale and multicenter study

Ke Su, Yanlin Liu, Pan Wang, Kun He, Fei Wang, Hao Chi, Mingyue Rao, Xueting Li, Lianbin Wen, Yanqiong Song, Jianwen Zhang, Tao Gu, Ke Xu, Qi Li, Jiali Chen, Zhenying Wu, Han Li, Weihong Huang, Lan Chen, Jian Tong, Hongyan Li, Xunjie Feng, Siyu Chen, Binbin Yang, Hongping Jin, Yue Yang, Hanlin Liu, Chao Yang, Ming Wu, Fangyu Xiong, Keyi Peng, Lechuan Zhu, Yaoyang Xu, Xue Tang, Zunyuan Tan, Xiaotong Luo, Hanyue Zheng, Yuxin Zhang, Lu Guo, Yunwei Han

Hepatol Int. 2022 Oct; 16(5): 1208–1219. Published online 2022 Aug 16. doi: 10.1007/s12072-022-10391-y

PMCID:: PMC9525341

Abstract Article PDF–1.8M

Select item 95132714.

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1

Amelia K. Luciano, Ekaterina D. Korobkina, Scott P. Lyons, John A. Haley, Shelagh M. Fluharty, Su Myung Jung, Arminja N. Kettenbach, David A. Guertin

J Biol Chem. 2022 Oct; 298(10): 102379. Published online 2022 Aug 13. doi: 10.1016/j.jbc.2022.102379

PMCID:: PMC9513271

Abstract Article PDF–2.7M

Select item 94853605.

Extracellular Hsp90α stimulates a unique innate gene profile in microglial cells with simultaneous activation of Nrf2 and protection from oxidative stress

Yuka Okusha, Benjamin J. Lang, Ayesha Murshid, Thiago J. Borges, Kristina M. Holton, Joanne Clark-Matott, Sachin Doshi, Tsuneya Ikezu, Stuart K. Calderwood

Cell Stress Chaperones. 2022 Sep; 27(5): 461–478. Published online 2022 Jun 10. doi: 10.1007/s12192-022-01279-9

Correction in:: Cell Stress Chaperones. 2022 Sep; 27(5): 479–483.

PMCID:: PMC9485360

Abstract Article PDF–10M

Select item 90560266.

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis

Fenglong Jiao, Clinton Yu, Andrew Wheat, Xiaorong Wang, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2022 Apr 30.

Published in final edited form as: Anal Chem. 2022 Mar 15; 94(10): 4236–4242. Published online 2022 Mar 2. doi: 10.1021/acs.analchem.1c04485

PMCID:: PMC9056026

Abstract Article PDF–1.0M

Select item 88644727.

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network

Rebecca Elizabeth Kattan, Han Han, Gayoung Seo, Bing Yang, Yongqi Lin, Max Dotson, Stephanie Pham, Yahya Menely, Wenqi Wang

Mol Cell Proteomics. 2022 Feb; 21(2): 100195. Published online 2022 Jan 8. doi: 10.1016/j.mcpro.2022.100195

PMCID:: PMC8864472

Abstract Article PDF–3.6M

Select item 83841588.

Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation

Nisan Denizce Can, Ezgi Basturk, Tugba Kizilboga, Izzet Mehmet Akcay, Baran Dingiloglu, Ozge Tatli, Sevilay Acar, Pelin Ozfiliz Kilbas, Efe Elbeyli, Serena Muratcioglu, Ayse Tarbin Jannuzzi, Attila Gursoy, Ozlem Keskin, Hamdi Levent Doganay, Betul Karademir Yilmaz, Gizem Dinler Doganay

PLoS One. 2021; 16(8): e0256640. Published online 2021 Aug 24. doi: 10.1371/journal.pone.0256640

PMCID:: PMC8384158

Abstract Article PDF–3.7M

Select item 83050439.

Extracellular Hsp90α Promotes Tumor Lymphangiogenesis and Lymph Node Metastasis in Breast Cancer

Qiaoyun Hou, Shuohua Chen, Qi An, Boya Li, Yan Fu, Yongzhang Luo

Int J Mol Sci. 2021 Jul; 22(14): 7747. Published online 2021 Jul 20. doi: 10.3390/ijms22147747

PMCID:: PMC8305043

Abstract Article PDF–3.9M

Select item 803576610.

NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer

Bing Li, Zhi-Peng Qi, Dong-Li He, Zhang-Han Chen, Jing-Yi Liu, Meng-Wai Wong, Jia-Wei Zhang, En-Pan Xu, Qiang Shi, Shi-Lun Cai, Di Sun, Li-Qing Yao, Ping-Hong Zhou, Yun-Shi Zhong

J Exp Clin Cancer Res. 2021; 40: 126. Published online 2021 Apr 10. doi: 10.1186/s13046-021-01920-y

PMCID:: PMC8035766

Abstract Article PDF–7.9M

Select item 796055011.

USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

Megan Perry, Meghan Biegert, Sai Sundeep Kollala, Halle Mallard, Grace Su, Manohar Kodavati, Natasha Kreiling, Alexander Holbrook, Gargi Ghosal

J Biol Chem. 2021 Jan-Jun; 296: 100396. Published online 2021 Feb 7. doi: 10.1016/j.jbc.2021.100396

PMCID:: PMC7960550

Abstract Article PDF–1.5M

Select item 742732712.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 691859413.

Endothelial-mesenchymal transition harnesses HSP90α-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma

Chi-Shuan Fan, Li-Li Chen, Tsu-An Hsu, Chia-Chi Chen, Kee Voon Chua, Chung-Pin Li, Tze-Sing Huang

J Hematol Oncol. 2019; 12: 138. Published online 2019 Dec 17. doi: 10.1186/s13045-019-0826-2

PMCID:: PMC6918594

Abstract Article PDF–3.0M

Select item 691487514.

Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study

Anca Bălănescu, Iustina Stan, Ioana Codreanu, Valentina Comănici, Eugenia Bălănescu, Paul Bălănescu

Dis Markers. 2019; 2019: 9560247. Published online 2019 Dec 3. doi: 10.1155/2019/9560247

PMCID:: PMC6914875

Abstract Article PDF–355K

Select item 677813715.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9