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Items: 1 to 20 of 90

1.
Diverse p120RasGAP interactions with doubly phosphorylated partners EphB4, p190RhoGAP, and Dok1
Kimberly J. Vish, Amy L. Stiegler, Titus J. Boggon
J Biol Chem. 2023 Sep; 299(9): 105098. Published online 2023 Jul 27. doi: 10.1016/j.jbc.2023.105098
PMCID:
PMC10470053
AbstractArticlePDF–3.2M
2.
Mutations in chromatin modifier and Ephrin signaling genes in Vein of Galen malformation
Daniel Duran, Xue Zeng, Sheng Chih Jin, Jungmin Choi, Carol Nelson-Williams, Bogdan Yatsula, Jonathan Gaillard, Charuta Gavankar Furey, Qiongshi Lu, Andrew T. Timberlake, Weilai Dong, Michelle A. Sorscher, Erin Loring, Jennifer Klein, August Allocco, Ava Hunt, Sierra Conine, Jason K. Karimy, Mark W. Youngblood, Jinwei Zhang, Michael L. DiLuna, Charles C. Matouk, Shrikant Mane, Irina R. Tikhonova, Christopher Castaldi, Francesc López-Giráldez, James Knight, Shozeb Haider, Mariya Soban, Seth L. Alper, Masaki Komiyama, Andrew F. Ducruet, Joseph M. Zabramski, Alan Dardik, Brian P. Walcott, Christopher J. Stapleton, Beverly Aagaard-Kienitz, Georges Rodesch, Eric Jackson, Edward R. Smith, Darren B. Orbach, Alejandro Berenstein, Kaya Bilguvar, Miikka Vikkula, Murat Gunel, Richard P. Lifton, Kristopher T. Kahle
Neuron. Author manuscript; available in PMC 2023 Jun 26.
Published in final edited form as: Neuron. 2019 Feb 6; 101(3): 429–443.e4. Published online 2018 Dec 18. doi: 10.1016/j.neuron.2018.11.041
PMCID:
PMC10292091
AbstractArticlePDF–1.8M
3.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
4.
Novel Isoform DTX3c Associates with UBE2N-UBA1 and Cdc48/p97 as Part of the EphB4 Degradation Complex Regulated by the Autocrine IGF-II/IRA Signal in Malignant Mesothelioma
Pierluigi Scalia, Carmen Merali, Carlos Barrero, Antonio Suma, Vincenzo Carnevale, Salim Merali, Stephen J. Williams
Int J Mol Sci. 2023 Apr; 24(8): 7380. Published online 2023 Apr 17. doi: 10.3390/ijms24087380
PMCID:
PMC10139083
AbstractArticlePDF–4.7M
5.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
6.
A dual-activity topoisomerase complex regulates mRNA translation and turnover
Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang
Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538
PMCID:
PMC9262614
AbstractArticlePDF–3.6M
7.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
8.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M
9.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
10.
EphrinB2–EphB4 Signaling in Neurooncological Disease
Andras Piffko, Christian Uhl, Peter Vajkoczy, Marcus Czabanka, Thomas Broggini
Int J Mol Sci. 2022 Feb; 23(3): 1679. Published online 2022 Jan 31. doi: 10.3390/ijms23031679
PMCID:
PMC8836162
AbstractArticlePDF–2.8M
11.
Assessing the association of common genetic variants in EPHB4 and RASA1 with phenotype severity in familial cerebral cavernous malformation
Foram Choksi, Shantel Weinsheimer, Jeffrey Nelson, Ludmila Pawlikowska, Christine K. Fox, Atif Zafar, Marc C. Mabray, Joseph Zabramski, Amy Akers, Blaine L. Hart, Leslie Morrison, Charles E. McCulloch, Helen Kim
Mol Genet Genomic Med. 2021 Oct; 9(10): e1794. Published online 2021 Sep 7. doi: 10.1002/mgg3.1794
PMCID:
PMC8580075
AbstractArticlePDF–464K
12.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
13.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
14.
Mutations in EPHB4 cause human venous valve aplasia
Oliver Lyons, James Walker, Christopher Seet, Mohammed Ikram, Adam Kuchta, Andrew Arnold, Magda Hernández-Vásquez, Maike Frye, Gema Vizcay-Barrena, Roland A. Fleck, Ashish S. Patel, Soundrie Padayachee, Peter Mortimer, Steve Jeffery, Siren Berland, Sahar Mansour, Pia Ostergaard, Taija Makinen, Bijan Modarai, Prakash Saha, Alberto Smith
JCI Insight. 2021 Sep 22; 6(18): e140952. Published online 2021 Sep 22. doi: 10.1172/jci.insight.140952
PMCID:
PMC8492339
AbstractArticlePDF–26M
15.
EphB4 as a Novel Target for the EGFR-Independent Suppressive Effects of Osimertinib on Cell Cycle Progression in Non-Small Cell Lung Cancer
Ren Nanamiya, Ryoko Saito-Koyama, Yasuhiro Miki, Chihiro Inoue, Teeranut Asavasupreechar, Jiro Abe, Ikuro Sato, Hironobu Sasano
Int J Mol Sci. 2021 Aug; 22(16): 8522. Published online 2021 Aug 7. doi: 10.3390/ijms22168522
PMCID:
PMC8395224
AbstractArticlePDF–3.3M
16.
Low Expression of EphB2, EphB3, and EphB4 in Bladder Cancer: Novel Potential Indicators of Muscular Invasion
Tae Ho Lee, Jin Hyung Heo, Ju-Yeon Jeong, Gee Hoon Lee, Dong Soo Park, Tae Hoen Kim
Yonsei Med J. 2021 Aug 1; 62(8): 679–690. Published online 2021 Jul 19. doi: 10.3349/ymj.2021.62.8.679
PMCID:
PMC8298868
AbstractArticlePDF–2.7M
17.
The effects of ephrinB2 signaling on proliferation and invasion in glioblastoma multiforme
Shilpa Bhatia, Sanjana Bukkapatnam, Benjamin Van Court, Andy Phan, Ayman Oweida, Jacob Gadwa, Adam C. Mueller, Miles Piper, Laurel Darragh, Diemmy Nguyen, Ahmed Gilani, Michael Knitz, Thomas Bickett, Adam Green, Sujatha Venkataraman, Rajeev Vibhakar, Diana Cittelly, Sana D. Karam
Mol Carcinog. Author manuscript; available in PMC 2021 Sep 1.
Published in final edited form as: Mol Carcinog. 2020 Sep; 59(9): 1064–1075. Published online 2020 Jun 22. doi: 10.1002/mc.23237
PMCID:
PMC8290424
AbstractArticlePDF–1.8M
18.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
19.
Identification of a novel EphB4 phosphodegron regulated by the autocrine IGFII/IRA axis in malignant mesothelioma
Pierluigi Scalia, Giuseppe Pandini, Vincenzo Carnevale, Antonio Giordano, Stephen J. Williams
Oncogene. 2019; 38(31): 5987–6001. Published online 2019 Jul 3. doi: 10.1038/s41388-019-0854-y
Correction in:
Oncogene. 2021; 40(8): 1551.
PMCID:
PMC8075896
AbstractArticlePDF–2.3M
20.
The Pyrazolo[3,4-d]pyrimidine-Based Kinase Inhibitor NVP-BHG712: Effects of Regioisomers on Tumor Growth, Perfusion, and Hypoxia in EphB4-Positive A375 Melanoma Xenografts
Christin Neuber, Alix Tröster, Reik Löser, Birgit Belter, Harald Schwalbe, Jens Pietzsch
Molecules. 2020 Nov; 25(21): 5115. Published online 2020 Nov 3. doi: 10.3390/molecules25215115
PMCID:
PMC7662635
AbstractArticlePDF–2.5M

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