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Items: 1 to 20 of 96

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration
Sima Khazaei, Carol CL Chen, Augusto Faria Andrade, Nisha Kabir, Pariya Azarafshar, Shahir M Morcos, Josiane Alves França, Mariana Lopes, Peder J Lund, Geoffroy Danieau, Samantha Worme, Lata Adnani, Nadine Nzirorera, Xiao Chen, Gayathri Yogarajah, Caterina Russo, Michele Zeinieh, Cassandra J Wong, Laura Bryant, Steven Hébert, Bethany Tong, Tianna S Sihota, Damien Faury, Evan Puligandla, Wajih Jawhar, Veronica Sandy, Mitra Cowan, Emily M Nakada, Loydie A Jerome-Majewska, Benjamin Ellezam, Carolina Cavalieri Gomes, Jonas Denecke, Davor Lessel, Marie T McDonald, Carolyn E Pizoli, Kathryn Taylor, Benjamin T Cocanougher, Elizabeth J Bhoj, Anne-Claude Gingras, Benjamin A Garcia, Chao Lu, Eric I Campos, Claudia L Kleinman, Livia Garzia, Nada Jabado
Cell. Author manuscript; available in PMC 2024 Mar 16.
Published in final edited form as: Cell. 2023 Mar 16; 186(6): 1162–1178.e20. doi: 10.1016/j.cell.2023.02.023
PMCID:
PMC10112048
AbstractArticlePDF–4.4M
3.
A knockout-first model of H3f3a gene targeting leads to developmental lethality
Kelly Bush, Vanessa Cervantes, Jennifer Q. Yee, Rachel H. Klein, Paul S. Knoepfler
Genesis. Author manuscript; available in PMC 2023 Mar 25.
Published in final edited form as: Genesis. 2023 Mar; 61(1-2): e23507. Published online 2023 Jan 19. doi: 10.1002/dvg.23507
PMCID:
PMC10038898
AbstractArticlePDF–968K
4.
PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation
Lea R Z Cohen, Binyamin Kaffe, Eden Deri, Chen Leibson, Malka Nissim-Rafinia, Moria Maman, Nofar Harpaz, Guy Ron, Efrat Shema, Eran Meshorer
Nucleic Acids Res. 2023 Feb 28; 51(4): 1662–1673. Published online 2022 Sep 26. doi: 10.1093/nar/gkac800
Correction in:
Nucleic Acids Res. 2023 Feb 28; 51(4): 1996.
PMCID:
PMC9976889
AbstractArticlePDF–3.9M
5.
Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity
Owen H. Funk, Yaman Qalieh, Daniel Z. Doyle, Mandy M. Lam, Kenneth Y. Kwan
Proc Natl Acad Sci U S A. 2022 Aug 9; 119(32): e2116956119. Published online 2022 Aug 5. doi: 10.1073/pnas.2116956119
PMCID:
PMC9371731
AbstractArticlePDF–7.3M
6.
Histone H3K36me2 and H3K36me3 form a chromatin platform essential for DNMT3A-dependent DNA methylation in mouse oocytes
Seiichi Yano, Takashi Ishiuchi, Shusaku Abe, Satoshi H. Namekawa, Gang Huang, Yoshihiro Ogawa, Hiroyuki Sasaki
Nat Commun. 2022; 13: 4440. Published online 2022 Aug 3. doi: 10.1038/s41467-022-32141-2
PMCID:
PMC9349174
AbstractArticlePDF–3.3M
7.
Dual role of histone variant H3.3B in spermatogenesis: positive regulation of piRNA transcription and implication in X-chromosome inactivation
Emeline Fontaine, Christophe Papin, Guillaume Martinez, Stéphanie Le Gras, Roland Abi Nahed, Patrick Héry, Thierry Buchou, Khalid Ouararhni, Bertrand Favier, Thierry Gautier, Jamal S M Sabir, Matthieu Gerard, Jan Bednar, Christophe Arnoult, Stefan Dimitrov, Ali Hamiche
Nucleic Acids Res. 2022 Jul 22; 50(13): 7350–7366. Published online 2022 Jun 29. doi: 10.1093/nar/gkac541
PMCID:
PMC9303386
AbstractArticlePDF–8.5M
8.
Histone variant H3.3 maintains adult haematopoietic stem cell homeostasis by enforcing chromatin adaptability
Peipei Guo, Ying Liu, Fuqiang Geng, Andrew W. Daman, Xiaoyu Liu, Liangwen Zhong, Arjun Ravishankar, Raphael Lis, José Gabriel Barcia Durán, Tomer Itkin, Fanying Tang, Tuo Zhang, Jenny Xiang, Koji Shido, Bi-sen Ding, Duancheng Wen, Steven Z. Josefowicz, Shahin Rafii
Nat Cell Biol. Author manuscript; available in PMC 2022 Jun 4.
Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 99–111. Published online 2021 Dec 27. doi: 10.1038/s41556-021-00795-7
PMCID:
PMC9166935
AbstractArticlePDF–7.7M
9.
Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase
Maheshi Udugama, Benjamin Vinod, F Lyn Chan, Linda Hii, Andrew Garvie, Philippe Collas, Paul Kalitsis, David Steer, Partha P Das, Pratibha Tripathi, Jeffrey R Mann, Hsiao P J Voon, Lee H Wong
Nucleic Acids Res. 2022 May 6; 50(8): 4500–4514. Published online 2022 Apr 22. doi: 10.1093/nar/gkac259
PMCID:
PMC9071403
AbstractArticlePDF–17M
10.
Gag‐like proteins: Novel mediators of prenatal alcohol exposure in neural development
Marisa R. Pinson, Dae D. Chung, Amanda H. Mahnke, Nihal A. Salem, Daniel Osorio, Vijay Nair, Elizabeth A. Payne, Jonathan J. del Real, James J. Cai, Rajesh C. Miranda
Alcohol Clin Exp Res. 2022 Apr; 46(4): 556–569. Published online 2022 Mar 2. doi: 10.1111/acer.14796
PMCID:
PMC9018584
AbstractArticlePDF–1.8M
11.
A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation
Shusaku Abe, Hiroaki Nagatomo, Hiroyuki Sasaki, Takashi Ishiuchi
Epigenetics. 2021; 16(10): 1123–1134. Published online 2020 Nov 16. doi: 10.1080/15592294.2020.1841873
PMCID:
PMC8510613
AbstractArticlePDF–7.2M
12.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
13.
Profiling of three H3F3A-mutated and denosumab-treated giant cell tumors of bone points to diverging pathways during progression and malignant transformation
Marc Hasenfratz, Kevin Mellert, Ralf Marienfeld, Alexandra von Baer, Markus Schultheiss, P. D. Roitman, L. A. Aponte-Tinao, Burkhard Lehner, Peter Möller, Gunhild Mechtersheimer, Thomas F. E. Barth
Sci Rep. 2021; 11: 5709. Published online 2021 Mar 11. doi: 10.1038/s41598-021-85319-x
PMCID:
PMC7952552
AbstractArticlePDF–2.1M
14.
Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells
Tina Yi-Ting Huang, Andrea Piunti, Jin Qi, Marc Morgan, Elizabeth Bartom, Ali Shilatifard, Amanda M. Saratsis
Acta Neuropathol Commun. 2020; 8: 219. Published online 2020 Dec 7. doi: 10.1186/s40478-020-01092-4
PMCID:
PMC7722426
AbstractArticlePDF–3.0M
15.
An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility
Carmen Navarro, Jing Lyu, Anna-Maria Katsori, Rozina Caridha, Simon J. Elsässer
Nat Commun. 2020; 11: 5095. Published online 2020 Oct 9. doi: 10.1038/s41467-020-18863-1
PMCID:
PMC7547087
AbstractArticlePDF–5.2M
16.
Transcription factor TEAD1 is essential for vascular development by promoting vascular smooth muscle differentiation
Tong Wen, Jinhua Liu, Xiangqin He, Kunzhe Dong, Guoqing Hu, Luyi Yu, Qin Yin, Islam Osman, Jingtian Peng, Zeqi Zheng, Hongbo Xin, David Fulton, Quansheng Du, Wei Zhang, Jiliang Zhou
Cell Death Differ. 2019 Dec; 26(12): 2790–2806. Published online 2019 Apr 25. doi: 10.1038/s41418-019-0335-4
PMCID:
PMC7224394
AbstractArticlePDF–6.5M
17.
KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
Aditya Sankar, Mads Lerdrup, Adeel Manaf, Jens Vilstrup Johansen, Javier Martin Gonzalez, Rehannah Borup, Robert Blanshard, Arne Klungland, Klaus Hansen, Claus Yding Andersen, John Arne Dahl, Kristian Helin, Eva R. Hoffmann
Nat Cell Biol. Author manuscript; available in PMC 2020 Sep 30.
Published in final edited form as: Nat Cell Biol. 2020 Apr 1; 22(4): 380–388. Published online 2020 Mar 30. doi: 10.1038/s41556-020-0494-z
PMCID:
PMC7212036
AbstractArticlePDF–5.2M
18.
Telencephalic Embryonic Subtractive Sequences: A Unique Collection of Neurodevelopmental Genes
Alessandro Bulfone, Pietro Carotenuto, Andrea Faedo, Veruska Aglio, Livia Garzia, Anna Maria Bello, Andrea Basile, Alessandra Andrè, Massimo Cocchia, Ombretta Guardiola, Andrea Ballabio, John L. R. Rubenstein, Massimo Zollo
J Neurosci. 2005 Aug 17; 25(33): 7586–7600. doi: 10.1523/JNEUROSCI.0522-05.2005
PMCID:
PMC6725394
AbstractArticlePDF–682K
19.
Nuclear Factor κB-Dependent Histone Acetylation is Specifically Involved in Persistent Forms of Memory
Noel Federman, Verónica de la Fuente, Gisela Zalcman, Nicoletta Corbi, Annalisa Onori, Claudio Passananti, Arturo Romano
J Neurosci. 2013 Apr 24; 33(17): 7603–7614. doi: 10.1523/JNEUROSCI.4181-12.2013
PMCID:
PMC6619586
AbstractArticlePDF–3.4M
20.
A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics
Mahesh Bachu, Tomohiko Tamura, Chao Chen, Ankur Narain, Vishal Nehru, Naoyuki Sarai, Sukhendu B. Ghosh, Anu Ghosh, Raghuveer Kavarthapu, Maria L. Dufau, Keiko Ozato
J Biol Chem. 2019 Feb 8; 294(6): 1904–1914. Published online 2018 Dec 14. doi: 10.1074/jbc.RA118.005550
PMCID:
PMC6369307
AbstractArticlePDF–6.2M

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