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Select item 107762461.

2B4: A potential target in Staphylococcus aureus associated allergic inflammation

Pratibha Gaur, Mansour Seaf, Nirit Trabelsi, Orly Marcu, Daria Gafarov, Ora Schueler-Furman, Ofer Mandelboim, Micha Ben-Zimra, Francesca Levi-Schaffer

Clin Exp Immunol. 2024 Jan; 215(1): 37–46. Published online 2023 Aug 16. doi: 10.1093/cei/uxad089

PMCID:: PMC10776246

Abstract Article PDF–1.5M

Select item 95095662.

A novel 2B4 receptor leads to worse pregnancy outcomes by facilitating TNF-α and IFN-γ production in dNK cells during Toxoplasma gondii infection

Xiaoyan Xu, Guangmei Zheng, Yushan Ren, Xiaohua He, Biwen Peng, Xuemei Hu, Wanhong Liu

Parasit Vectors. 2022; 15: 337. Published online 2022 Sep 24. doi: 10.1186/s13071-022-05455-9

PMCID:: PMC9509566

Abstract Article PDF–6.5M

Select item 70948713.

Sepsis Erodes CD8⁺ Memory T Cell Protective Immunity Against an EBV Homolog in a 2B4-Dependent Manner

J Xie, RL Crepeau, CW Chen, W Zhang, S Otani, CM Coopersmith, ML Ford

J Leukoc Biol. Author manuscript; available in PMC 2020 Mar 25.

Published in final edited form as: J Leukoc Biol. 2019 Mar; 105(3): 565–575. Published online 2019 Jan 9. doi: 10.1002/JLB.4A0718-292R

PMCID:: PMC7094871

Abstract Article PDF–955K

Select item 69488544.

2B4 but not PD-1 blockade improves mortality in septic animals with preexisting malignancy

Ching-wen Chen, Ming Xue, Wenxiao Zhang, Jianfeng Xie, Craig M. Coopersmith, Mandy L. Ford

JCI Insight. 2019 Nov 14; 4(22): e127867. Published online 2019 Nov 14. doi: 10.1172/jci.insight.127867

PMCID:: PMC6948854

Abstract Article PDF–12M

Select item 65383605.

Increased attrition of memory T cells during sepsis requires 2B4

Jianfeng Xie, Ching-wen Chen, Yini Sun, Sonia J. Laurie, Wenxiao Zhang, Shunsuke Otani, Gregory S. Martin, Craig M. Coopersmith, Mandy L. Ford

JCI Insight. 2019 May 2; 4(9): e126030. Published online 2019 May 2. doi: 10.1172/jci.insight.126030

PMCID:: PMC6538360

Abstract Article PDF–2.2M

Select item 61038056.

2B4 Mediates Inhibition of CD8⁺ T Cell Responses via Attenuation of Glycolysis and Cell Division

Sonia J. Laurie, Danya Liu, Maylene E. Wagener, Phoebe E. Stark, Cox Terhorst, Mandy L. Ford

J Immunol. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: J Immunol. 2018 Sep 1; 201(5): 1536–1548. Published online 2018 Jul 16. doi: 10.4049/jimmunol.1701240

PMCID:: PMC6103805

Abstract Article PDF–977K

Select item 58906517.

Gut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens

Allison Cabinian, Daniel Sinsimer, May Tang, Youngsoon Jang, Bongkum Choi, Yasmina Laouar, Amale Laouar

Gut. 2018 May; 67(5): 847–859. Published online 2017 Mar 24. doi: 10.1136/gutjnl-2016-313214

PMCID:: PMC5890651

Abstract Article PDF–2.1M

Select item 55874008.

2B4-mediated coinhibition of CD4⁺ T cells underlies mortality in experimental sepsis

Ching-wen Chen, Rohit Mittal, Nathan J. Klingensmith, Eileen M. Burd, Cox Terhorst, Greg S. Martin, Craig M. Coopersmith, Mandy L. Ford

J Immunol. Author manuscript; available in PMC 2018 Sep 15.

Published in final edited form as: J Immunol. 2017 Sep 15; 199(6): 1961–1966. Published online 2017 Aug 2. doi: 10.4049/jimmunol.1700375

PMCID:: PMC5587400

Abstract Article PDF–1.1M

Select item 55652689.

SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin

Jun Chen, Ming-Chao Zhong, Huaijian Guo, Dominique Davidson, Sabrin Mishel, Yan Lu, Inmoo Rhee, Luis-Alberto Pérez-Quintero, Shaohua Zhang, Mario-Ernesto Cruz-Munoz, Ning Wu, Donald C. Vinh, Meenal Sinha, Virginie Calderon, Clifford A. Lowell, Jayne S. Danska, André Veillette

Nature. Author manuscript; available in PMC 2017 Aug 21.

Published in final edited form as: Nature. 2017 Apr 27; 544(7651): 493–497. Published online 2017 Apr 19. doi: 10.1038/nature22076

PMCID:: PMC5565268

Abstract Article PDF–5.4M

Select item 503080910.

Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1

Huaijian Guo, Stacey A. Cranert, Yan Lu, Ming-Chao Zhong, Shaohua Zhang, Jun Chen, Rui Li, Sarah E. Mahl, Ning Wu, Dominique Davidson, Stephen N. Waggoner, André Veillette

J Exp Med. 2016 Sep 19; 213(10): 2187–2207. doi: 10.1084/jem.20160552

Correction in:: J Exp Med. 2016 Sep 19; 213(10): 2227.

PMCID:: PMC5030809

Abstract Article PDF–4.3M

Select item 455498711.

2B4 Is Dispensable for T-Dependent B Cell Immune Responses, but Its Deficiency Leads to Enhanced T-Independent Responses Due to an Increase in Peritoneal Cavity B1b Cells

Avijit Ray, Cheng-Yin Yuan, Nichole M. Miller, Hong Mei, Bonnie N. Dittel

PLoS One. 2015; 10(8): e0137314. Published online 2015 Aug 31. doi: 10.1371/journal.pone.0137314

PMCID:: PMC4554987

Abstract Article PDF–989K

Select item 447672912.

Inhibition of Donor-Reactive CD8+ T Cell Responses by Selective CD28 Blockade Is Independent of Reduced ICOS Expression

Danya Liu, Suzanne J. Suchard, Steve G. Nadler, Mandy L. Ford

PLoS One. 2015; 10(6): e0130490. Published online 2015 Jun 22. doi: 10.1371/journal.pone.0130490

PMCID:: PMC4476729

Abstract Article PDF–2.9M

Select item 440951613.

SLAMF4 is a Negative Regulator of Expansion of Cytotoxic Intra-epithelial CD8+ T Cells That Maintains Homeostasis in the Small Intestine

Michael S. O’Keeffe, Joo-Hye Song, Gongxian Liao, Jaime De Calisto, Peter J. Halibozek, J. Rodrigo Mora, Atul K. Bhan, Ninghai Wang, Hans-Christian Reinecker, Cox Terhorst

Gastroenterology. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Gastroenterology. 2015 May; 148(5): 991–1001.e4. Published online 2015 Feb 10. doi: 10.1053/j.gastro.2015.02.003

PMCID:: PMC4409516

Abstract Article PDF–1.9M

Select item 425666814.

Homotypic NK cell-to-cell communication controls cytokine responsiveness of innate immune NK cells

Tae-Jin Kim, Miju Kim, Hye Mi Kim, Seon Ah Lim, Eun-Ok Kim, Kwanghee Kim, Kwang Hoon Song, Jiyoung Kim, Vinay Kumar, Cassian Yee, Junsang Doh, Kyung-Mi Lee

Sci Rep. 2014; 4: 7157. Published online 2014 Dec 5. doi: 10.1038/srep07157

PMCID:: PMC4256668

Abstract Article PDF–2.4M

Select item 392056515.

2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8⁺ T cell responses

Danya Liu, Scott M. Krummey, I. Raul Badell, Maylene Wagener, Lumelle A. Schneeweis, Dawn K. Stetsko, Suzanne J. Suchard, Steven G. Nadler, Mandy L. Ford

J Exp Med. 2014 Feb 10; 211(2): 297–311. doi: 10.1084/jem.20130902

PMCID:: PMC3920565

Abstract Article PDF–3.7M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163