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Items: 1 to 20 of 67

1.
Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis
Amandine Jarysta, Abigail LD Tadenev, Matthew Day, Barry Krawchuk, Benjamin E Low, Michael V Wiles, Basile Tarchini
eLife. 2024; 12: RP88186. Published online 2024 Apr 23. doi: 10.7554/eLife.88186
PMCID:
PMC11037916
AbstractArticlePDF–8.9M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
4.
miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network
Salvatore Pulcrano, Roberto De Gregorio, Claudia De Sanctis, Floriana Volpicelli, Rosa Maria Piscitelli, Luisa Speranza, Carla Perrone-Capano, Umberto di Porzio, Massimiliano Caiazzo, Alessandro Martini, Cecilia Giacomet, Diego Medina, Rajeshwar Awatramani, Davide Viggiano, Mauro Federici, Nicola B. Mercuri, Ezia Guatteo, Gian Carlo Bellenchi
J Neurosci. 2023 Nov 29; 43(48): 8104–8125. doi: 10.1523/JNEUROSCI.0431-23.2023
PMCID:
PMC10697421
AbstractArticlePDF–5.4M
5.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
6.
Gαi1/3 mediate Netrin-1-CD146-activated signaling and angiogenesis
Ya Li, Jin-long Chai, Xin Shi, Yu Feng, Jia-jun Li, Li-na Zhou, Cong Cao, Ke-ran Li
Theranostics. 2023; 13(7): 2319–2336. Published online 2023 Apr 17. doi: 10.7150/thno.80749
PMCID:
PMC10157725
AbstractArticlePDF–10M
7.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
AbstractArticlePDF–5.3M
8.
SIRT1 regulates cardiomyocyte alignment during maturation
Yi Fang, Wei Fan, Xiaojiang Xu, Agnes K. Janoshazi, David C. Fargo, Xiaoling Li
J Cell Sci. 2022 Apr 1; 135(7): jcs259076. Published online 2022 Apr 1. doi: 10.1242/jcs.259076
PMCID:
PMC9016619
AbstractArticle
9.
In Vivo Metabolic Roles of G Proteins of the Gi Family Studied With Novel Mouse Models
Jürgen Wess
Endocrinology. 2022 Jan; 163(1): bqab245. Published online 2021 Dec 5. doi: 10.1210/endocr/bqab245
PMCID:
PMC8691396
AbstractArticle
10.
Requirement of Gαi1 and Gαi3 in interleukin-4-induced signaling, macrophage M2 polarization and allergic asthma response
Jin-yu Bai, Ya Li, Guan-hua Xue, Ke-ran Li, Yu-Fan Zheng, Zhi-qing Zhang, Qin Jiang, Yuan-yuan Liu, Xiao-zhong Zhou, Cong Cao
Theranostics. 2021; 11(10): 4894–4909. Published online 2021 Mar 4. doi: 10.7150/thno.56383
PMCID:
PMC7978294
AbstractArticlePDF–3.2M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
Allosteric Inhibition of Adenylyl Cyclase Type 5 by G-Protein: A Molecular Dynamics Study
Elisa Frezza, Tina-Méryl Amans, Juliette Martin
Biomolecules. 2020 Sep; 10(9): 1330. Published online 2020 Sep 17. doi: 10.3390/biom10091330
PMCID:
PMC7563791
AbstractArticlePDF–18M
13.
GINIP, a Gαi-Interacting Protein, Functions as a Key Modulator of Peripheral GABAB Receptor-Mediated Analgesia
Stéphane Gaillard, Laure Lo Re, Annabelle Mantilleri, Régine Hepp, Louise Urien, Pascale Malapert, Serge Alonso, Michael Deage, Charline Kambrun, Marc Landry, Sarah A. Low, Abdelkrim Alloui, Bertrand Lambolez, Grégory Scherrer, Yves Le Feuvre, Emmanuel Bourinet, Aziz Moqrich
Neuron. Author manuscript; available in PMC 2020 Jul 10.
Published in final edited form as: Neuron. 2014 Oct 1; 84(1): 123–136. Published online 2014 Sep 18. doi: 10.1016/j.neuron.2014.08.056
PMCID:
PMC7348640
AbstractArticlePDF–3.1M
14.
Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
Lei Wang, Sai P. Pydi, Lu Zhu, Luiz F. Barella, Yinghong Cui, Oksana Gavrilova, Kendra K. Bence, Cecile Vernochet, Jürgen Wess
Nat Commun. 2020; 11: 2995. Published online 2020 Jun 12. doi: 10.1038/s41467-020-16756-x
PMCID:
PMC7293267
AbstractArticlePDF–3.6M
15.
GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2
Zhi-Wei Li, Beicheng Sun, Ting Gong, Sheng Guo, Jianhua Zhang, Junlong Wang, Atsushi Sugawara, Meisheng Jiang, Junjun Yan, Alexandra Gurary, Xin Zheng, Bifeng Gao, Shu-Yuan Xiao, Wenlian Chen, Chi Ma, Christine Farrar, Chenjun Zhu, Owen T. M. Chan, Can Xin, Andrew Winnicki, John Winnicki, Mingxin Tang, Ryan Park, Mary Winnicki, Katrina Diener, Zhanwei Wang, Qicai Liu, Catherine H. Chu, Zhaohui L. Arter, Peibin Yue, Lindsay Alpert, George S. Hui, Peiwen Fei, James Turkson, Wentian Yang, Guangyu Wu, Ailin Tao, Joe W. Ramos, Stefan Moisyadi, Randall F. Holcombe, Wei Jia, Lutz Birnbaumer, Xiqiao Zhou, Wen-Ming Chu
Gastroenterology. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Gastroenterology. 2019 Jun; 156(8): 2297–2312. Published online 2019 Mar 2. doi: 10.1053/j.gastro.2019.02.040
PMCID:
PMC6628260
AbstractArticlePDF–4.3M
16.
Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6
Caroline Bull Melsom, Marie-Victoire Cosson, Øivind Ørstavik, Ngai Chin Lai, H. Kirk Hammond, Jan-Bjørn Osnes, Tor Skomedal, Viacheslav Nikolaev, Finn Olav Levy, Kurt Allen Krobert
PLoS One. 2019; 14(6): e0218110. Published online 2019 Jun 7. doi: 10.1371/journal.pone.0218110
PMCID:
PMC6556981
AbstractArticlePDF–2.3M
17.
A link between planar polarity and staircase-like bundle architecture in hair cells
Basile Tarchini, Abigail L. D. Tadenev, Nicholas Devanney, Michel Cayouette
Development. 2016 Nov 1; 143(21): 3926–3932. Published online 2016 Nov 1. doi: 10.1242/dev.139089
PMCID:
PMC6514398
AbstractArticle
18.
Intrinsic planar polarity mechanisms influence the position-dependent regulation of synapse properties in inner hair cells
Philippe Jean, Özge Demet Özçete, Basile Tarchini, Tobias Moser
Proc Natl Acad Sci U S A. 2019 Apr 30; 116(18): 9084–9093. Published online 2019 Apr 11. doi: 10.1073/pnas.1818358116
PMCID:
PMC6500111
AbstractArticlePDF–17M
19.
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization
Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II
Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053
Correction in:
Proteomes. 2019 Mar; 7(1): 7.
PMCID:
PMC6313900
AbstractArticlePDF–2.5M
20.
RNA binding proteins co-localize with small tau inclusions in tauopathy
Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin
Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5
PMCID:
PMC6069705
AbstractArticlePDF–5.5M

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