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Items: 1 to 20 of 30

1.
microRNA-449a reduces growth hormone-stimulated senescent cell burden through PI3K-mTOR signaling
Sarah Noureddine, Jia Nie, Augusto Schneider, Vinal Menon, Zoubeida Fliesen, Joseph Dhahbi, Berta Victoria, Jeremiah Oyer, Liza Robles-Carrillo, Allancer Divino De Carvalho Nunes, Sarah Ashiqueali, Artur Janusz, Alicja Copik, Paul D. Robbins, Nicolas Musi, Michal M. Masternak
Proc Natl Acad Sci U S A. 2023 Apr 4; 120(14): e2213207120. Published online 2023 Mar 28. doi: 10.1073/pnas.2213207120
PMCID:
PMC10083567
AbstractArticlePDF–1.6M
2.
miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly
Merit Wildung, Christian Herr, Dietmar Riedel, Cornelia Wiedwald, Alena Moiseenko, Fidel Ramírez, Hataitip Tasena, Maren Heimerl, Mihai Alevra, Naira Movsisyan, Maike Schuldt, Larisa Volceanov-Hahn, Sharen Provoost, Tabea Nöthe-Menchen, Diana Urrego, Bernard Freytag, Julia Wallmeier, Christoph Beisswenger, Robert Bals, Maarten van den Berge, Wim Timens, Pieter S. Hiemstra, Corry-Anke Brandsma, Tania Maes, Stefan Andreas, Irene H. Heijink, Luis A. Pardo, Muriel Lizé
Int J Mol Sci. 2022 Jul; 23(14): 7749. Published online 2022 Jul 13. doi: 10.3390/ijms23147749
PMCID:
PMC9320302
AbstractArticlePDF–4.7M
3.
MicroRNAs mediate precise control of spinal interneuron populations to exert delicate sensory-to-motor outputs
Shih-Hsin Chang, Yi-Ching Su, Mien Chang, Jun-An Chen
eLife. 2021; 10: e63768. Published online 2021 Mar 31. doi: 10.7554/eLife.63768
PMCID:
PMC8075582
AbstractArticlePDF–5.5M
4.
Long non-coding RNA GAS5 aggravates myocardial depression in mice with sepsis via the microRNA-449b/HMGB1 axis and the NF-κB signaling pathway
Hongfeng Gao, Huijing Ma, Min Gao, Aichun Chen, Shujuan Zha, Jixi Yan
Biosci Rep. 2021 Apr 30; 41(4): BSR20201738. Published online 2021 Apr 9. doi: 10.1042/BSR20201738
PMCID:
PMC8035624
AbstractArticlePDF–1.9M
5.
miR-449a-5p suppresses CDK6 expression to inhibit cardiomyocyte proliferation
Bing Li, Zhi Wang, Fan Yang, Jing Huang, Xingwei Hu, Shiyan Deng, Maobo Tian, Xiaoyun Si
Mol Med Rep. 2021 Jan; 23(1): 14. Published online 2020 Nov 3. doi: 10.3892/mmr.2020.11652
PMCID:
PMC7673318
AbstractArticlePDF–4.2M
6.
Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis
Merit Wildung, Tilman Uli Esser, Katie Baker Grausam, Cornelia Wiedwald, Larisa Volceanov-Hahn, Dietmar Riedel, Sabine Beuermann, Li Li, Jessica Zylla, Ann-Kathrin Guenther, Magdalena Wienken, Evrim Ercetin, Zhiyuan Han, Felix Bremmer, Orr Shomroni, Stefan Andreas, Haotian Zhao, Muriel Lizé
Cell Death Differ. 2019 Dec; 26(12): 2740–2757. Published online 2019 May 8. doi: 10.1038/s41418-019-0332-7
PMCID:
PMC7224178
AbstractArticlePDF–4.2M
7.
MicroRNA-449a regulates the progression of brain aging by targeting SCN2B in SAMP8 mice
Ya-Xin Tan, Ying Hong, Shui Jiang, Min-Nan Lu, Shan Li, Bo Chen, Li Zhang, Tao Hu, Rui Mao, Rong Mei, Yan-Bin Xiyang
Int J Mol Med. 2020 Apr; 45(4): 1091–1102. Published online 2020 Feb 13. doi: 10.3892/ijmm.2020.4502
PMCID:
PMC7053848
AbstractArticlePDF–1.1M
8.
miR-449a regulates insulin signalling by targeting the Notch ligand, Jag1 in skeletal muscle cells
Shagun Poddar, Devesh Kesharwani, Malabika Datta
Cell Commun Signal. 2019; 17: 84. Published online 2019 Jul 25. doi: 10.1186/s12964-019-0394-7
PMCID:
PMC6659245
AbstractArticlePDF–2.2M
9.
The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system
Pengcheng Shu, Chao Wu, Wei Liu, Xiangbin Ruan, Chang Liu, Lin Hou, Yi Zeng, Hongye Fu, Ming Wang, Pan Chen, Xiaoling Zhang, Bin Yin, Jiangang Yuan, Boqin Qiang, Xiaozhong Peng
J Biol Chem. 2019 Mar 8; 294(10): 3444–3453. Published online 2018 Dec 21. doi: 10.1074/jbc.RA118.004390
PMCID:
PMC6416447
AbstractArticlePDF–3.4M
10.
Motile cilia of the male reproductive system require miR-34/miR-449 for development and function to generate luminal turbulence
Shuiqiao Yuan, Yue Liu, Hongying Peng, Chong Tang, Grant W. Hennig, Zhuqing Wang, Li Wang, Tian Yu, Rachel Klukovich, Ying Zhang, Huili Zheng, Chen Xu, Jingwen Wu, Rex A. Hess, Wei Yan
Proc Natl Acad Sci U S A. 2019 Feb 26; 116(9): 3584–3593. Published online 2019 Jan 18. doi: 10.1073/pnas.1817018116
PMCID:
PMC6397547
AbstractArticlePDF–3.7M
11.
Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades
Ningning Li, Ying Zhang, Kastytis Sidlauskas, Matthew Ellis, Ian Evans, Paul Frankel, Joanne Lau, Tedani El-Hassan, Loredana Guglielmi, Jessica Broni, Angela Richard-Loendt, Sebastian Brandner
Oncogene. 2018; 37(31): 4313–4333. Published online 2018 May 3. doi: 10.1038/s41388-018-0277-1
PMCID:
PMC6072706
AbstractArticlePDF–5.3M
12.
microRNA-449a modulates medullary thymic epithelial cell differentiation
Pengfei Chen, Haohao Zhang, Xiaohua Sun, Yiming Hu, Wenxia Jiang, Zhanjie Liu, Sanhong Liu, Xiaoren Zhang
Sci Rep. 2017; 7: 15915. Published online 2017 Nov 21. doi: 10.1038/s41598-017-16162-2
PMCID:
PMC5698406
AbstractArticlePDF–9.4M
13.
Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit
Tobias Otto, Sheyla V. Candido, Mary S. Pilarz, Ewa Sicinska, Roderick T. Bronson, Michaela Bowden, Iga A. Lachowicz, Kristin Mulry, Anne Fassl, Richard C. Han, Emmanuelle S. Jecrois, Piotr Sicinski
Proc Natl Acad Sci U S A. 2017 Oct 3; 114(40): 10660–10665. Published online 2017 Sep 18. doi: 10.1073/pnas.1702914114
PMCID:
PMC5635871
AbstractArticlePDF–1.3M
14.
MicroRNA-449a deficiency promotes colon carcinogenesis
Masanori Niki, Kohei Nakajima, Daichi Ishikawa, Jun Nishida, Chieko Ishifune, Shin-ichi Tsukumo, Mitsuo Shimada, Shinji Nagahiro, Yoshinori Mitamura, Koji Yasutomo
Sci Rep. 2017; 7: 10696. Published online 2017 Sep 6. doi: 10.1038/s41598-017-10500-0
PMCID:
PMC5587792
AbstractArticlePDF–2.8M
15.
miR-449a Contributes to Glucocorticoid-Induced CRF-R1 Downregulation in the Pituitary During Stress
Takahiro Nemoto, Asuka Mano, Tamotsu Shibasaki
Mol Endocrinol. 2013 Oct; 27(10): 1593–1602. Published online 2013 Jul 26. doi: 10.1210/me.2012-1357
PMCID:
PMC5427883
AbstractArticle
16.
MicroRNA‐34/449 controls mitotic spindle orientation during mammalian cortex development
Juan Pablo Fededa, Christopher Esk, Beata Mierzwa, Rugile Stanyte, Shuiqiao Yuan, Huili Zheng, Klaus Ebnet, Wei Yan, Juergen A Knoblich, Daniel W Gerlich
EMBO J. 2016 Nov 15; 35(22): 2386–2398. Published online 2016 Oct 5. doi: 10.15252/embj.201694056
PMCID:
PMC5109238
AbstractArticlePDF–1.9M
17.
Deregulation of MiR-34b/Sox2 Predicts Prostate Cancer Progression
Irene Forno, Stefano Ferrero, Maria Veronica Russo, Giacomo Gazzano, Sara Giangiobbe, Emanuele Montanari, Alberto Del Nero, Bernardo Rocco, Giancarlo Albo, Lucia R. Languino, Dario C. Altieri, Valentina Vaira, Silvano Bosari
PLoS One. 2015; 10(6): e0130060. Published online 2015 Jun 24. doi: 10.1371/journal.pone.0130060
PMCID:
PMC4479381
AbstractArticlePDF–7.0M
18.
Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci
Stefano Comazzetto, Monica Di Giacomo, Kasper Dindler Rasmussen, Christian Much, Chiara Azzi, Emerald Perlas, Marcos Morgan, Dónal O'Carroll
PLoS Genet. 2014 Oct; 10(10): e1004597. Published online 2014 Oct 16. doi: 10.1371/journal.pgen.1004597
PMCID:
PMC4199480
AbstractArticlePDF–1.7M
19.
Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis
Jingwen Wu, Jianqiang Bao, Minkyung Kim, Shuiqiao Yuan, Chong Tang, Huili Zheng, Grant S. Mastick, Chen Xu, Wei Yan
Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28): E2851–E2857. Published online 2014 Jun 30. doi: 10.1073/pnas.1407777111
PMCID:
PMC4104921
AbstractArticlePDF–1.8M
20.
MicroRNA-449 and MicroRNA-34b/c Function Redundantly in Murine Testes by Targeting E2F Transcription Factor-Retinoblastoma Protein (E2F-pRb) Pathway
Jianqiang Bao, Ding Li, Li Wang, Jingwen Wu, Yanqin Hu, Zhugang Wang, Yan Chen, Xinkai Cao, Cizhong Jiang, Wei Yan, Chen Xu
J Biol Chem. 2012 Jun 22; 287(26): 21686–21698. Published online 2012 May 8. doi: 10.1074/jbc.M111.328054
PMCID:
PMC3381132
AbstractArticlePDF–4.8M

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