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Select item 105305651.

TSG6 hyaluronan matrix remodeling dampens the inflammatory response during colitis

Nansy Albtoush, Kimberly A. Queisser, Ash Zawerton, Mark E. Lauer, Ellen J. Beswick, Aaron C Petrey

Matrix Biol. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Matrix Biol. 2023 Aug; 121: 149–166. Published online 2023 Jun 29. doi: 10.1016/j.matbio.2023.06.007

PMCID:: PMC10530565

Abstract Article PDF–4.0M

Select item 100516872.

Characterization of the Involvement of Tumour Necrosis Factor (TNF)-α-Stimulated Gene 6 (TSG-6) in Ischemic Brain Injury Caused by Middle Cerebral Artery Occlusion in Mouse

Chiara Di Santo, Daniele La Russa, Rosaria Greco, Alessandra Persico, Anna Maria Zanaboni, Giacinto Bagetta, Diana Amantea

Int J Mol Sci. 2023 Mar; 24(6): 5800. Published online 2023 Mar 18. doi: 10.3390/ijms24065800

PMCID:: PMC10051687

Abstract Article PDF–1.8M

Select item 97007413.

Mesenchymal stem/stromal cells primed by inflammatory cytokines alleviate psoriasis-like inflammation via the TSG-6-neutrophil axis

Yayun Ding, Pixia Gong, Junjie Jiang, Chao Feng, Yanan Li, Xiao Su, Xiaojing Bai, Chenchang Xu, Chunxiao Liu, Jianxin Yang, Jiankai Fang, Xiaocao Ji, Yongjing Chen, Peishan Li, Lingchuan Guo, Changshun Shao, Yufang Shi

Cell Death Dis. 2022 Nov; 13(11): 996. Published online 2022 Nov 25. doi: 10.1038/s41419-022-05445-w

PMCID:: PMC9700741

Abstract Article PDF–12M

Select item 83362664.

Anti-inflammatory protein TNFα-stimulated gene-6 (TSG-6) reduces inflammatory response after brain injury in mice

Kazadi Nadine Mutoji, Mingxia Sun, Amanda Nash, Sudan Puri, Vincent Hascall, Vivien J. Coulson-Thomas

BMC Immunol. 2021; 22: 52. Published online 2021 Aug 4. doi: 10.1186/s12865-021-00443-7

PMCID:: PMC8336266

Abstract Article PDF–5.2M

Select item 77497185.

Cutaneous Wounds in Mice Lacking Tumor Necrosis Factor-stimulated Gene-6 Exhibit Delayed Closure and an Abnormal Inflammatory Response

Sajina Shakya, Judith A. Mack, Minou Alipour, Edward V. Maytin

J Invest Dermatol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Invest Dermatol. 2020 Dec; 140(12): 2505–2514. Published online 2020 May 15. doi: 10.1016/j.jid.2020.04.015

PMCID:: PMC7749718

Abstract Article PDF–1.9M

Select item 70102336.

TSG-6 in extracellular vesicles from canine mesenchymal stem/stromal is a major factor in relieving DSS-induced colitis

Ju-Hyun An, Qiang Li, Min-Ok Ryu, A-Ryung Nam, Dong-Ha Bhang, Yun-Chan Jung, Woo-Jin Song, Hwa-Young Youn

PLoS One. 2020; 15(2): e0220756. Published online 2020 Feb 10. doi: 10.1371/journal.pone.0220756

PMCID:: PMC7010233

Abstract Article PDF–2.5M

Select item 69585987.

Mesenchymal stem cells alleviate liver injury induced by chronic-binge ethanol feeding in mice via release of TSG6 and suppression of STAT3 activation

Yue-Meng Wan, Zhi-qiang Li, Qiong Zhou, Chang Liu, Men-Jie Wang, Hui-Xin Wu, Yun-Zhen Mu, Yue-Feng He, Yuan Zhang, Xi-Nan Wu, Yu-Hua Li, Zhi-Yuan Xu, Hua-Mei Wu, Ying Xu, Jin-Hui Yang, Xiao-Fang Wang

Stem Cell Res Ther. 2020; 11: 24. Published online 2020 Jan 13. doi: 10.1186/s13287-019-1547-8

PMCID:: PMC6958598

Abstract Article PDF–7.0M

Select item 63152918.

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1‐integrin

Giuliana Fossati, Davide Pozzi, Alice Canzi, Filippo Mirabella, Sonia Valentino, Raffaella Morini, Elsa Ghirardini, Fabia Filipello, Milena Moretti, Cecilia Gotti, Douglas S Annis, Deane F Mosher, Cecilia Garlanda, Barbara Bottazzi, Giulia Taraboletti, Alberto Mantovani, Michela Matteoli, Elisabetta Menna

EMBO J. 2019 Jan 3; 38(1): e99529. Published online 2018 Nov 5. doi: 10.15252/embj.201899529

PMCID:: PMC6315291

Abstract Article PDF–2.6M

Select item 62071949.

Midgut laterality is driven by hyaluronan on the right

Aravind Sivakumar, Aparna Mahadevan, Mark E. Lauer, Ricky J. Narvaez, Siddesh Ramesh, Cora M. Demler, Nathan R. Souchet, Vincent C. Hascall, Ron J. Midura, Stavros Garantziotis, David B. Frank, Koji Kimata, Natasza A. Kurpios

Dev Cell. Author manuscript; available in PMC 2019 Sep 10.

Published in final edited form as: Dev Cell. 2018 Sep 10; 46(5): 533–551.e5. Published online 2018 Aug 30. doi: 10.1016/j.devcel.2018.08.002

PMCID:: PMC6207194

Abstract Article PDF–2.1M

Select item 585568710.

Emerging Roles of Tumor Necrosis Factor-Stimulated Gene-6 in the Pathophysiology and Treatment of Atherosclerosis

Rena Watanabe, Yuki Sato, Nana Ozawa, Yui Takahashi, Shinji Koba, Takuya Watanabe

Int J Mol Sci. 2018 Feb; 19(2): 465. Published online 2018 Feb 5. doi: 10.3390/ijms19020465

PMCID:: PMC5855687

Abstract Article PDF–3.2M

Select item 574306211.

TNF-stimulated gene 6 promotes formation of hyaluronan–inter-α-inhibitor heavy chain complexes necessary for ozone-induced airway hyperresponsiveness

Vandy P. Stober, Collin G. Johnson, Alana Majors, Mark E. Lauer, Valbona Cali, Ronald J. Midura, Hans-Georg Wisniewski, Mark A. Aronica, Stavros Garantziotis

J Biol Chem. 2017 Dec 22; 292(51): 20845–20858. Published online 2017 Nov 9. doi: 10.1074/jbc.M116.756627

PMCID:: PMC5743062

Abstract Article PDF–3.4M

Select item 562827612.

Tumor necrosis factor-inducible gene 6 protein ameliorates chronic liver damage by promoting autophagy formation in mice

Sihyung Wang, Chanbin Lee, Jieun Kim, Jeongeun Hyun, Minso Lim, Hyuk-Jin Cha, Seh-Hoon Oh, Yung Hyun Choi, Youngmi Jung

Exp Mol Med. 2017 Sep; 49(9): e380. Published online 2017 Sep 22. doi: 10.1038/emm.2017.140

Expression of Concern in:: Exp Mol Med. 2021 Feb; 53(2): 300.

PMCID:: PMC5628276

Abstract Article PDF–5.7M

Select item 558447313.

Hyaluronan Rich Microenvironment in the Limbal Stem Cell Niche Regulates Limbal Stem Cell Differentiation

Tarsis F. Gesteira, Mingxia Sun, Yvette M. Coulson-Thomas, Yu Yamaguchi, Lung-Kun Yeh, Vincent Hascall, Vivien J. Coulson-Thomas

Invest Ophthalmol Vis Sci. 2017 Sep; 58(11): 4407–4421. doi: 10.1167/iovs.17-22326

PMCID:: PMC5584473

Abstract Article PDF–2.3M

Select item 543724214.

Phospholipase C-related but catalytically inactive proteins regulate ovarian follicle development

Miho Matsuda, Masato Hirata

J Biol Chem. 2017 May 19; 292(20): 8369–8380. Published online 2017 Mar 30. doi: 10.1074/jbc.M116.759928

PMCID:: PMC5437242

Abstract Article PDF–3.5M

Select item 516717015.

TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury

Manish Mittal, Chinnaswamy Tiruppathi, Saroj Nepal, You-Yang Zhao, Dagmara Grzych, Dheeraj Soni, Darwin J. Prockop, Asrar B. Malik

Proc Natl Acad Sci U S A. 2016 Dec 13; 113(50): E8151–E8158. Published online 2016 Nov 28. doi: 10.1073/pnas.1614935113

PMCID:: PMC5167170

Abstract Article PDF–1.4M

Select item 513715916.

Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-α Stimulated Gene/Protein 6

Zhigang He, Jie Hua, Daohai Qian, Jian Gong, Shengping Lin, Chenglei Xu, Ge Wei, Hongbo Meng, Tingsong Yang, Bo Zhou, Zhenshun Song

Sci Rep. 2016; 6: 38438. Published online 2016 Dec 5. doi: 10.1038/srep38438

PMCID:: PMC5137159

Abstract Article PDF–3.4M

Select item 502568117.

Tumor Necrosis Factor-stimulated Gene-6 (TSG-6) Is Constitutively Expressed in Adult Central Nervous System (CNS) and Associated with Astrocyte-mediated Glial Scar Formation following Spinal Cord Injury

Vivien J. Coulson-Thomas, Mark E. Lauer, Sara Soleman, Chao Zhao, Vincent C. Hascall, Anthony J. Day, James W. Fawcett

J Biol Chem. 2016 Sep 16; 291(38): 19939–19952. Published online 2016 Jul 19. doi: 10.1074/jbc.M115.710673

PMCID:: PMC5025681

Abstract Article PDF–4.1M

Select item 471422718.

Hyaluronan Rafts on Airway Epithelial Cells

Amina Abbadi, Mark Lauer, Shadi Swaidani, Aimin Wang, Vincent Hascall

J Biol Chem. 2016 Jan 15; 291(3): 1448–1455. Published online 2015 Nov 24. doi: 10.1074/jbc.M115.704288

PMCID:: PMC4714227

Abstract Article PDF–1.4M

Select item 466138619.

Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix

David C. Briggs, Holly L. Birchenough, Tariq Ali, Marilyn S. Rugg, Jon P. Waltho, Elena Ievoli, Thomas A. Jowitt, Jan J. Enghild, Ralf P. Richter, Antonietta Salustri, Caroline M. Milner, Anthony J. Day

J Biol Chem. 2015 Nov 27; 290(48): 28708–28723. Published online 2015 Oct 14. doi: 10.1074/jbc.M115.669838

PMCID:: PMC4661386

Abstract Article PDF–2.6M

Select item 456624820.

Acute and Temporal Expression of Tumor Necrosis Factor (TNF)-α-stimulated Gene 6 Product, TSG6, in Mesenchymal Stem Cells Creates Microenvironments Required for Their Successful Transplantation into Muscle Tissue

Shigeko Torihashi, Mioko Ho, Yuji Kawakubo, Kazumi Komatsu, Masataka Nagai, Yuri Hirayama, Yuka Kawabata, Nana Takenaka-Ninagawa, Orawan Wanachewin, Lisheng Zhuo, Koji Kimata

J Biol Chem. 2015 Sep 11; 290(37): 22771–22781. Published online 2015 Jul 15. doi: 10.1074/jbc.M114.629774