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Items: 1 to 20 of 39

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia
Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju
J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787
PMCID:
PMC8988008
AbstractArticlePDF–6.1M
3.
ADAM8 signaling drives neutrophil migration and ARDS severity
Catharina Conrad, Daniela Yildiz, Simon J. Cleary, Andreas Margraf, Lena Cook, Uwe Schlomann, Barry Panaretou, Jessica L. Bowser, Harry Karmouty-Quintana, Jiwen Li, Nathaniel K. Berg, Samuel C. Martin, Ahmad Aljohmani, S. Farshid Moussavi-Harami, Kristin M. Wang, Jennifer J. Tian, Mélia Magnen, Colin Valet, Longhui Qiu, Jonathan P. Singer, Holger K. Eltzschig, CAPSys Study Group, Wilhelm Bertrams, Susanne Herold, Norbert Suttorp, Bernd Schmeck, Zachary T. Ball, Alexander Zarbock, Mark R. Looney, Jörg W. Bartsch
JCI Insight. 2022 Feb 8; 7(3): e149870. Published online 2022 Feb 8. doi: 10.1172/jci.insight.149870
PMCID:
PMC8855804
AbstractArticlePDF–8.2M
4.
Suppression of ADAM8 attenuates angiotensin II-induced cardiac fibrosis and endothelial-mesenchymal transition via inhibiting TGF-β1/Smad2/Smad3 pathways
Lixia Yao, Weihua Shao, Yan Chen, Suxing Wang, Dai Huang
Exp Anim. 2022; 71(1): 90–99. Published online 2021 Oct 7. doi: 10.1538/expanim.21-0064
PMCID:
PMC8828410
AbstractArticlePDF–10M
5.
Expression of the Metalloproteinase ADAM8 Is Upregulated in Liver Inflammation Models and Enhances Cytokine Release In Vitro
Tanzeela Awan, Aaron Babendreyer, Justyna Wozniak, Abid Mahmood Alvi, Viktor Sterzer, Lena Cook, Jörg W. Bartsch, Christian Liedtke, Daniela Yildiz, Andreas Ludwig
Mediators Inflamm. 2021; 2021: 6665028. Published online 2021 Mar 11. doi: 10.1155/2021/6665028
PMCID:
PMC7987468
AbstractArticlePDF–1.9M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Expression levels of the metalloproteinase ADAM8 critically regulate proliferation, migration and malignant signalling events in hepatoma cells
Tanzeela Awan, Aaron Babendreyer, Abid Mahmood Alvi, Stefan Düsterhöft, Daniela Lambertz, Jörg W. Bartsch, Christian Liedtke, Andreas Ludwig
J Cell Mol Med. 2021 Feb; 25(4): 1982–1999. Published online 2020 Dec 13. doi: 10.1111/jcmm.16015
PMCID:
PMC7882935
AbstractArticlePDF–3.1M
8.
Vasculature-driven stem cell population coordinates tissue scaling in dynamic organs
R. Ichijo, M. Kabata, H. Kidoya, F. Muramatsu, R. Ishibashi, K. Abe, K. Tsutsui, H. Kubo, Y. Iizuka, S. Kitano, H. Miyachi, Y. Kubota, H. Fujiwara, A. Sada, T. Yamamoto, F. Toyoshima
Sci Adv. 2021 Feb; 7(7): eabd2575. Published online 2021 Feb 10. doi: 10.1126/sciadv.abd2575
PMCID:
PMC7875541
AbstractArticlePDF–1.3M
9.
Elevated inflammatory gene expression in intervertebral disc tissues in mice with ADAM8 inactivated
Yejia Zhang, Zuozhen Tian, David Gerard, Lutian Yao, Frances S. Shofer, Gabriella Cs-Szabo, Ling Qin, Maurizio Pacifici, Motomi Enomoto-Iwamoto
Sci Rep. 2021; 11: 1804. Published online 2021 Jan 19. doi: 10.1038/s41598-021-81495-y
PMCID:
PMC7815795
AbstractArticlePDF–2.0M
10.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
11.
Tumor Necrosis Factor α Induces a Metalloprotease-Disintegrin, ADAM8 (CD 156): Implications for Neuron–Glia Interactions during Neurodegeneration
Uwe Schlomann, Silvia Rathke-Hartlieb, Shunsuke Yamamoto, Harald Jockusch, Jörg W. Bartsch
J Neurosci. 2000 Nov 1; 20(21): 7964–7971. doi: 10.1523/JNEUROSCI.20-21-07964.2000
PMCID:
PMC6772711
AbstractArticlePDF–7.3M
12.
Tumor Necrosis Factor-α (TNF-α) Regulates Shedding of TNF-α Receptor 1 by the Metalloprotease-Disintegrin ADAM8: Evidence for a Protease-Regulated Feedback Loop in Neuroprotection
Jörg W. Bartsch, Dirk Wildeboer, Garrit Koller, Silvia Naus, Andrea Rittger, Marcia L. Moss, Yuji Minai, Harald Jockusch
J Neurosci. 2010 Sep 8; 30(36): 12210–12218. doi: 10.1523/JNEUROSCI.1520-10.2010
PMCID:
PMC6633558
AbstractArticlePDF–2.0M
13.
A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease
Francesca Polverino, Joselyn Rojas-Quintero, Xiaoyun Wang, Hans Petersen, Li Zhang, Xiaoyan Gai, Andrew Higham, Duo Zhang, Kushagra Gupta, Amit Rout, Ilyas Yambayev, Victor Pinto-Plata, Lynette M. Sholl, Danen Cunoosamy, Bartolomé R. Celli, James Goldring, Dave Singh, Yohannes Tesfaigzi, Jadwiga Wedzicha, Henric Olsson, Caroline A. Owen
Am J Respir Crit Care Med. 2018 Nov 15; 198(10): 1254–1267. Published online 2018 Nov 15. doi: 10.1164/rccm.201707-1331OC
PMCID:
PMC6290938
AbstractArticlePDF–1.7M
14.
Intervertebral Disc Degeneration in a Percutaneous Mouse Tail Injury Model
Zuozhen Tian, Xiaoyuan Ma, Miersalijiang Yasen, Robert L. Mauck, Ling Qin, Frances S. Shofer, Lachlan J. Smith, Maurizio Pacifici, Motomi Enomoto-Iwamoto, Yejia Zhang
Am J Phys Med Rehabil. Author manuscript; available in PMC 2019 Mar 1.
Published in final edited form as: Am J Phys Med Rehabil. 2018 Mar; 97(3): 170–177. doi: 10.1097/PHM.0000000000000818
PMCID:
PMC5823709
AbstractArticlePDF–770K
15.
Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression
Kosta Theodorou, Emiel P. C. van der Vorst, Marion J. Gijbels, Ine M. J. Wolfs, Mike Jeurissen, Thomas L. Theelen, Judith C. Sluimer, Erwin Wijnands, Jack P. Cleutjens, Yu Li, Yvonne Jansen, Christian Weber, Andreas Ludwig, Jacob F. Bentzon, Jörg W. Bartsch, Erik A. L. Biessen, Marjo M. P. C. Donners
Sci Rep. 2017; 7: 11670. Published online 2017 Sep 15. doi: 10.1038/s41598-017-10549-x
PMCID:
PMC5601942
AbstractArticlePDF–6.3M
16.
Deletion of Stk40 impairs definitive erythropoiesis in the mouse fetal liver
Lina Wang, Hongyao Yu, Hui Cheng, Ke He, Zhuoqing Fang, Laixiang Ge, Tao Cheng, Ying Jin
Cell Death Dis. 2017 Mar; 8(3): e2722. Published online 2017 Mar 30. doi: 10.1038/cddis.2017.148
PMCID:
PMC5386544
AbstractArticlePDF–2.5M
17.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
18.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
19.
A Murine Model for Retinopathy of Prematurity Identifies Endothelial Cell Proliferation as a Potential Mechanism for Plus Disease
Victor H. Guaiquil, Nina J. Hewing, Michael F. Chiang, Mark I. Rosenblatt, R. V. Paul Chan, Carl P. Blobel
Invest Ophthalmol Vis Sci. 2013 Aug; 54(8): 5294–5302. Published online 2013 Aug 7. doi: 10.1167/iovs.12-11492
PMCID:
PMC3738219
AbstractArticlePDF–1.5M
20.
Adam8 Limits the Development of Allergic Airway Inflammation in Mice
Martin D. Knolle, Takahiro Nakajima, Anja Hergrueter, Kushagra Gupta, Francesca Polverino, Vanessa J. Craig, Susanne E. Fyfe, Muhammad Zahid, Perdita Permaul, Manuela Cernadas, Gilbert Montano, Yohannes Tesfaigzi, Lynette Sholl, Lester Kobzik, Elliot Israel, Caroline A. Owen
J Immunol. Author manuscript; available in PMC 2014 Jun 15.
Published in final edited form as: J Immunol. 2013 Jun 15; 190(12): 6434–6449. Published online 2013 May 13. doi: 10.4049/jimmunol.1202329
PMCID:
PMC3679335
AbstractArticlePDF–5.0M

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