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Items: 1 to 20 of 85

1.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
2.
The tacrolimus-binding protein FKBP8 directs myosin light chain kinase-dependent barrier regulation and is a potential therapeutic target in Crohn’s disease
Li Zuo, Wei-Ting Kuo, Feng Cao, Sandra D. Chanez-Paredes, Daniel Zeve, Prabhath Mannam, Léa Jean-François, Anne Day, W Vallen Graham, Yan Y. Sweat, Nitesh Shashikanth, David T. Breault, Jerrold R. Turner
Gut. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: Gut. 2023 May; 72(5): 870–881. Published online 2022 May 10. doi: 10.1136/gutjnl-2021-326534
PMCID:
PMC9977574
AbstractArticlePDF–5.2M
3.
Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression
Wenjing Xiao, Jianqun Wang, Xiaojing Wang, Shuang Cai, Yanhua Guo, Lin Ye, Dan Li, Anpei Hu, Shikai Jin, Boling Yuan, Yi Zhou, Qilan Li, Qiangsong Tong, Liduan Zheng
Autophagy. 2022; 18(11): 2615–2635. Published online 2022 Mar 6. doi: 10.1080/15548627.2022.2044651
PMCID:
PMC9629121
AbstractArticlePDF–8.1M
4.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
5.
SIK2 promotes ovarian cancer cell motility and metastasis by phosphorylating MYLK
Xiu Shi, Xuejiao Yu, Juan Wang, Shimin Bian, Qiutong Li, Fengqing Fu, Xinwei Zou, Lin Zhang, Robert C. Bast, Jr., Zhen Lu, Lingchuan Guo, Youguo Chen, Jinhua Zhou
Mol Oncol. 2022 Jul; 16(13): 2558–2574. Published online 2022 Mar 25. doi: 10.1002/1878-0261.13208
PMCID:
PMC9251837
AbstractArticlePDF–12M
6.
Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0
Fujun Hou, Zeyu Sun, Yue Deng, Siyu Chen, Xiyuan Yang, Feiyang Ji, Menghao Zhou, Keyi Ren, Dongli Pan
Front Microbiol. 2022; 13: 856471. Published online 2022 Apr 18. doi: 10.3389/fmicb.2022.856471
PMCID:
PMC9062659
AbstractArticlePDF–3.5M
7.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
8.
Myosin light chain kinase-driven myosin II turnover regulates actin cortex contractility during mitosis
Nilay Taneja, Sophie M. Baillargeon, Dylan T. Burnette
Mol Biol Cell. 2021 Oct 1; 32(20): br3. doi: 10.1091/mbc.E20-09-0608
PMCID:
PMC8684764
AbstractArticlePDF–2.4M
9.
CHD1L prevents lipopolysaccharide-induced hepatocellular carcinomar cell death by activating hnRNP A2/B1-nmMYLK axis
Guangliang Wang, Xiaofeng Zhang, Wei Cheng, Yanxuan Mo, Juan Chen, Zhiming Cao, Xiaogang Chen, Huiqin Cui, Shanshan Liu, Li Huang, Ming Liu, Lei Ma, Ning-Fang Ma
Cell Death Dis. 2021 Oct; 12(10): 891. Published online 2021 Sep 29. doi: 10.1038/s41419-021-04167-9
Correction in:
Cell Death Dis. 2022 Mar; 13(3): 196.
PMCID:
PMC8481269
AbstractArticlePDF–3.7M
10.
A novel tumor suppressor role of myosin light chain kinase splice variants through downregulation of the TEAD4/CD44 axis
Yen-Ju Huang, Tsung-Chun Lee, Yu-Chen Pai, Been-Ren Lin, Jerrold R Turner, Linda Chia-Hui Yu
Carcinogenesis. 2021 Jul; 42(7): 961–974. Published online 2021 May 17. doi: 10.1093/carcin/bgab038
PMCID:
PMC8283729
AbstractArticlePDF–35M
11.
MYLK and PTGS1 Genetic Variations Associated with Osteoporosis and Benign Breast Tumors in Korean Women
Hye-Won Cho, Hyun-Seok Jin, Yong-Bin Eom
Genes (Basel) 2021 Mar; 12(3): 378. Published online 2021 Mar 6. doi: 10.3390/genes12030378
PMCID:
PMC7998336
AbstractArticlePDF–1.0M
12.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
13.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
Ivanka R. Sevrieva, Birgit Brandmeier, Saraswathi Ponnam, Mathias Gautel, Malcolm Irving, Kenneth S. Campbell, Yin-Biao Sun, Thomas Kampourakis
J Biol Chem. 2020 Apr 3; 295(14): 4398–4410. Published online 2020 Feb 21. doi: 10.1074/jbc.RA119.011945
PMCID:
PMC7135997
AbstractArticlePDF–3.3M
16.
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Susan A. Kennedy, Mohamed-Ali Jarboui, Sriganesh Srihari, Cinzia Raso, Kenneth Bryan, Layal Dernayka, Theodosia Charitou, Manuel Bernal-Llinares, Carlos Herrera-Montavez, Aleksandar Krstic, David Matallanas, Max Kotlyar, Igor Jurisica, Jasna Curak, Victoria Wong, Igor Stagljar, Thierry LeBihan, Lisa Imrie, Priyanka Pillai, Miriam A. Lynn, Erik Fasterius, Cristina Al-Khalili Szigyarto, James Breen, Christina Kiel, Luis Serrano, Nora Rauch, Oleksii Rukhlenko, Boris N. Kholodenko, Luis F. Iglesias-Martinez, Colm J. Ryan, Ruth Pilkington, Patrizia Cammareri, Owen Sansom, Steven Shave, Manfred Auer, Nicola Horn, Franziska Klose, Marius Ueffing, Karsten Boldt, David J. Lynn, Walter Kolch
Nat Commun. 2020; 11: 499. Published online 2020 Jan 24. doi: 10.1038/s41467-019-14224-9
PMCID:
PMC6981206
AbstractArticlePDF–3.7M
17.
Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence
Izumi Horikawa, Kaori Fujita, Lisa M. Miller Jenkins, Yukiharu Hiyoshi, Abdul M. Mondal, Borivoj Vojtesek, David P. Lane, Ettore Appella, Curtis C. Harris
Nat Commun. Author manuscript; available in PMC 2019 Jul 29.
Published in final edited form as: Nat Commun. 2014 Aug 21; 5: 4706. Published online 2014 Aug 21. doi: 10.1038/ncomms5706
PMCID:
PMC6662595
AbstractArticlePDF–1.6M
18.
An Interaction Network of the Human SEPT9 Established by Quantitative Mass Spectrometry
Matthias Hecht, Reinhild Rösler, Sebastian Wiese, Nils Johnsson, Thomas Gronemeyer
G3 (Bethesda) 2019 Jun; 9(6): 1869–1880. Published online 2019 Apr 11. doi: 10.1534/g3.119.400197
PMCID:
PMC6553528
AbstractArticlePDF–2.9M
19.
Intracellular MLCK1 diversion reverses barrier loss to restore mucosal homeostasis
W Vallen Graham, Weiqi He, Amanda M. Marchiando, Juanmin Zha, Gurminder Singh, Hua-Shan Li, Amlan Biswas, Ma. Lora Drizella M. Ong, Zhi-Hui Jiang, Wangsun Choi, Harmon Zuccola, Yitang Wang, James Griffith, Jingshing Wu, Harry J. Rosenberg, Yingmin Wang, Scott B. Snapper, David Ostrov, Stephen C. Meredith, Lawrence W. Miller, Jerrold R. Turner
Nat Med. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Nat Med. 2019 Apr; 25(4): 690–700. Published online 2019 Apr 1. doi: 10.1038/s41591-019-0393-7
PMCID:
PMC6461392
AbstractArticlePDF–1.9M
20.
MYLK Mutations: Aortic Disease Presentation, Pregnancy Risk, and Characterization of Pathogenic Missense Variants
Stephanie E. Wallace, Ellen S. Regalado, Limin Gong, Alexandra L. Janda, Dong-chuan Guo, Claudio F. Russo, Richard J. Kulmacz, Nadine Hanna, Guillaume Jondeau, Catherine Boileau, Pauline Arnaud, Montalcino Aortic Consortium, Kwanghyuk Lee, Suzanne M. Leal, Matias Hannuksela, Bo Carlberg, Tami Johnston, Christian Antolik, Ellen M. Hostetler, Roberto Colombo, Dianna M. Milewicz
Genet Med. Author manuscript; available in PMC 2019 Mar 5.
Published in final edited form as: Genet Med. 2019 Jan; 21(1): 144–151. Published online 2018 Jun 20. doi: 10.1038/s41436-018-0038-0
PMCID:
PMC6400320
AbstractArticlePDF–874K

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