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Select item 114478351.

Yeast Tor complex 1 phosphorylates eIF4E‐binding protein, Caf20

Yoshiaki Kamada, Ryoko Ando, Shingo Izawa, Akira Matsuura

Genes Cells. 2023 Nov; 28(11): 789–799. Published online 2023 Sep 12. doi: 10.1111/gtc.13067

PMCID:: PMC11447835

Abstract Article PDF–3.0M

Select item 113578572.

Ccr4-not ubiquitin ligase signaling regulates ribosomal protein homeostasis and inhibits 40S ribosomal autophagy

Daniel L. Johnson, Ravinder Kumar, David Kakhniashvili, Lawrence M. Pfeffer, R. Nicholas Laribee

J Biol Chem. 2024 Aug; 300(8): 107582. Published online 2024 Jul 16. doi: 10.1016/j.jbc.2024.107582

PMCID:: PMC11357857

Abstract Article PDF–3.9M

Select item 111726673.

Expression of Wild-Type and Mutant Human TDP-43 in Yeast Inhibits TOROID (TORC1 Organized in Inhibited Domain) Formation and Autophagy Proportionally to the Levels of TDP-43 Toxicity

Sangeun Park, Sei-Kyoung Park, Susan W. Liebman

Int J Mol Sci. 2024 Jun; 25(11): 6258. Published online 2024 Jun 6. doi: 10.3390/ijms25116258

PMCID:: PMC11172667

Abstract Article PDF–2.1M

Select item 109416554.

Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes

Yoshiaki Kamada, Chiharu Umeda, Yukio Mukai, Hokuto Ohtsuka, Yoko Otsubo, Akira Yamashita, Takahiro Kosugi

J Cell Sci. 2024 Feb 15; 137(4): jcs261625. Published online 2024 Feb 28. doi: 10.1242/jcs.261625

PMCID:: PMC10941655

Abstract Article

Select item 108724775.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001386.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105481767.

TOR‐mediated Ypt1 phosphorylation regulates autophagy initiation complex assembly

Weijing Yao, Yuting Chen, Yingcong Chen, Pengwei Zhao, Jing Liu, Yi Zhang, Qiang Jiang, Choufei Wu, Yu Xie, Siyu Fan, Miao Ye, Yigang Wang, Yuyao Feng, Xue Bai, Mingzhu Fan, Shan Feng, Juan Wang, Yixian Cui, Hongguang Xia, Cheng Ma, Zhiping Xie, Liqin Zhang, Qiming Sun, Wei Liu, Cong Yi

EMBO J. 2023 Oct; 42(19): e112814. Published online 2023 Aug 28. doi: 10.15252/embj.2022112814

PMCID:: PMC10548176

Abstract Article PDF–19M

Select item 102977008.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 102922109.

Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin

Sanjeev Kumar Choudhry, Maxwell L. Neal, Song Li, Arti T. Navare, Trevor Van Eeuwen, Richard W. Wozniak, Fred D. Mast, Michael P. Rout, John D. Aitchison

J Cell Biol. 2023 Sep 4; 222(9): e202207060. Published online 2023 Jun 26. doi: 10.1083/jcb.202207060

PMCID:: PMC10292210

Abstract Article PDF–5.9M

Select item 963098610.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 957451411.

Elucidation of the interaction proteome of mitochondrial chaperone Hsp78 highlights its role in protein aggregation during heat stress

Witold Jaworek, Marc Sylvester, Giovanna Cenini, Wolfgang Voos

J Biol Chem. 2022 Oct; 298(10): 102494. Published online 2022 Sep 15. doi: 10.1016/j.jbc.2022.102494

PMCID:: PMC9574514

Abstract Article PDF–1.9M

Select item 928602312.

Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton

Curr Biol. 2022 Jul 11; 32(13): 2884–2896.e6. doi: 10.1016/j.cub.2022.05.019

PMCID:: PMC9286023

Abstract Article

Select item 920981113.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 903130914.

TORC1 Signaling Controls the Stability and Function of α-Arrestins Aly1 and Aly2

Ray W. Bowman, II, Eric M. Jordahl, Sydnie Davis, Stefanie Hedayati, Hannah Barsouk, Nejla Ozbaki-Yagan, Annette Chiang, Yang Li, Allyson F. O’Donnell

Biomolecules. 2022 Apr; 12(4): 533. Published online 2022 Mar 31. doi: 10.3390/biom12040533

PMCID:: PMC9031309

Abstract Article PDF–12M

Select item 898260015.

Bur1 functions with TORC1 for vacuole‐mediated cell cycle progression

Yui Jin, Natsuko Jin, Yu Oikawa, Ron Benyair, Michiko Koizumi, Thomas E Wilson, Yoshinori Ohsumi, Lois S Weisman

EMBO Rep. 2022 Apr; 23(4): e53477. Published online 2022 Feb 15. doi: 10.15252/embr.202153477

PMCID:: PMC8982600

Abstract Article PDF–2.2M

Select item 866458616.

TORC1 signaling modulates Cdk8-dependent GAL gene expression in Saccharomyces cerevisiae

Riley Horvath, Nicole Hawe, Cindy Lam, Konstantin Mestnikov, Mariam Eji-Lasisi, John Rohde, Ivan Sadowski

Genetics. 2021 Dec; 219(4): iyab168. Published online 2021 Oct 5. doi: 10.1093/genetics/iyab168

PMCID:: PMC8664586

Abstract Article PDF–1.2M

Select item 859956417.

Pterocarpus marsupium extract extends replicative lifespan in budding yeast

Mitchell B. Lee, Michael G. Kiflezghi, Mitsuhiro Tsuchiya, Brian Wasko, Daniel T. Carr, Priya A. Uppal, Katherine A. Grayden, Yordanos C. Elala, Tu Anh Nguyen, Jesse Wang, Priya Ragosti, Sunny Nguyen, Yan Ting Zhao, Deborah Kim, Socheata Thon, Irika Sinha, Thao T. Tang, Ngoc H. B. Tran, Thu H. B. Tran, Margarete D. Moore, Mary Ann K. Li, Karl Rodriguez, Daniel E. L. Promislow, Matt Kaeberlein

GeroScience. 2021 Oct; 43(5): 2595–2609. Published online 2021 Jul 23. doi: 10.1007/s11357-021-00418-x