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Select item 106415241.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 104499032.

The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension

Katharina Sporbeck, Maximilian L. Haas, Carmen J. Pastor-Maldonado, David S. Schüssele, Catherine Hunter, Zsuzsanna Takacs, Ana L. Diogo de Oliveira, Mirita Franz-Wachtel, Chara Charsou, Simon G. Pfisterer, Andrea Gubas, Patricia K. Haller, Roland L. Knorr, Manuel Kaulich, Boris Macek, Eeva-Liisa Eskelinen, Anne Simonsen, Tassula Proikas-Cezanne

Commun Biol. 2023; 6: 872. Published online 2023 Aug 24. doi: 10.1038/s42003-023-05236-9

PMCID:: PMC10449903

Abstract Article PDF–5.2M

Select item 91086103.

CROP: a retromer‐PROPPIN complex mediating membrane fission in the endo‐lysosomal system

Thibault Courtellemont, Maria Giovanna De Leo, Navin Gopaldass, Andreas Mayer

EMBO J. 2022 May; 41(10): e109646. Published online 2022 Apr 25. doi: 10.15252/embj.2021109646

PMCID:: PMC9108610

Abstract Article PDF–8.1M

Select item 86322854.

WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanisms

Maria Giovanna De Leo, Philipp Berger, Andreas Mayer

Autophagy. 2021; 17(11): 3644–3670. Published online 2021 Mar 8. doi: 10.1080/15548627.2021.1886830

PMCID:: PMC8632285

Abstract Article PDF–9.0M

Select item 83867405.

Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy

Waka Kojima, Koji Yamano, Hidetaka Kosako, Kenichiro Imai, Reika Kikuchi, Keiji Tanaka, Noriyuki Matsuda

Autophagy. 2021; 17(8): 2011–2036. Published online 2021 Jan 26. doi: 10.1080/15548627.2021.1874133

PMCID:: PMC8386740

Abstract Article PDF–13M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79158027.

The Role of Cardiolipin as a Scaffold Mitochondrial Phospholipid in Autophagosome Formation: In Vitro Evidence

Valeria Manganelli, Antonella Capozzi, Serena Recalchi, Gloria Riitano, Vincenzo Mattei, Agostina Longo, Roberta Misasi, Tina Garofalo, Maurizio Sorice

Biomolecules. 2021 Feb; 11(2): 222. Published online 2021 Feb 5. doi: 10.3390/biom11020222

PMCID:: PMC7915802

Abstract Article PDF–3.0M

Select item 66291518.

WIPI1 is a conserved mediator of right ventricular failure

Christos Tzimas, Christoph D. Rau, Petra E. Buergisser, Gaston Jean-Louis, Jr., Katherine Lee, Jeffrey Chukwuneke, Wen Dun, Yibin Wang, Emily J. Tsai

JCI Insight. 2019 Jun 6; 4(11): e122929. Published online 2019 Jun 6. doi: 10.1172/jci.insight.122929

PMCID:: PMC6629151

Abstract Article PDF–17M

Select item 66257939.

The autophagic membrane tether ATG2A transfers lipids between membranes

Shintaro Maeda, Chinatsu Otomo, Takanori Otomo

eLife. 2019; 8: e45777. Published online 2019 Jul 4. doi: 10.7554/eLife.45777

PMCID:: PMC6625793

Abstract Article PDF–3.8M

Select item 630481810.

WIPI1, BAG1, and PEX3 Autophagy-Related Genes Are Relevant Melanoma Markers

Daniela D'Arcangelo, Claudia Giampietri, Mario Muscio, Francesca Scatozza, Francesco Facchiano, Antonio Facchiano

Oxid Med Cell Longev. 2018; 2018: 1471682. Published online 2018 Dec 2. doi: 10.1155/2018/1471682

PMCID:: PMC6304818

Abstract Article PDF–1.2M

Select item 559655811.

TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A

Yizhe Sun, Yingyu Chen, Jingyu Zhang, Lulu Cao, Minwei He, Xi Liu, Ning Zhao, Ang Yin, He Huang, Lu Wang

Cell Death Dis. 2017 Aug; 8(8): e3031. Published online 2017 Aug 31. doi: 10.1038/cddis.2017.370

PMCID:: PMC5596558

Abstract Article PDF–4.8M

Select item 555930612.

A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220

Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang

Cancer Res. Author manuscript; available in PMC 2018 Aug 15.

Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4402–4413. Published online 2017 Jun 16. doi: 10.1158/0008-5472.CAN-16-1627

PMCID:: PMC5559306

Abstract Article PDF–885K

Select item 553161113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 546003814.

WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy

Daniela Bakula, Amelie J. Müller, Theresia Zuleger, Zsuzsanna Takacs, Mirita Franz-Wachtel, Ann-Katrin Thost, Daniel Brigger, Mario P. Tschan, Tancred Frickey, Horst Robenek, Boris Macek, Tassula Proikas-Cezanne

Nat Commun. 2017; 8: 15637. Published online 2017 May 31. doi: 10.1038/ncomms15637

PMCID:: PMC5460038

Abstract Article PDF–4.5M

Select item 461721115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043