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Items: 1 to 20 of 140

1.
ELANE rs17223045C/T and rs3761007G/A variants: Protective factors against COVID-19
José Manuel Fragoso, Gilberto Vargas-Alarcón, Ángel Emmanuel Martínez-Flores, Isela Montufar-Robles, Rosa Elda Barbosa-Cobos, Gustavo Rojas-Velasco, Julian Ramírez-Bello
Biomol Biomed. 2024 Jun 1; 24(3): 665–672. Published online 2024 Jun 1. doi: 10.17305/bb.2023.9940
PMCID:
PMC11088890
AbstractArticlePDF–809K
2.
Neutrophil Elastase Degrades Histone Deacetylases and Sirtuin 1 in Primary Human Monocyte Derived Macrophages
Shuo Zheng, Gamze B. Bulut, Apparao B. Kummarapurugu, Jonathan Ma, Judith A. Voynow
Int J Mol Sci. 2024 Apr; 25(8): 4265. Published online 2024 Apr 12. doi: 10.3390/ijms25084265
PMCID:
PMC11050352
AbstractArticlePDF–3.7M
3.
Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase–mediated proteolysis of corticosteroid-binding globulin
Anastasia Chernykh, Jodie L. Abrahams, Oliver C. Grant, Lucas Kambanis, Zeynep Sumer-Bayraktar, Julian Ugonotti, Rebeca Kawahara, Leo Corcilius, Richard J. Payne, Robert J. Woods, Morten Thaysen-Andersen
J Biol Chem. 2024 Jan; 300(1): 105519. Published online 2023 Nov 30. doi: 10.1016/j.jbc.2023.105519
PMCID:
PMC10784704
AbstractArticlePDF–5.2M
4.
Elevated first-trimester neutrophil elastase and proteinase 3 increase the risk of gestational diabetes mellitus and adverse fetal outcomes
Lihong Wang, Zhoujunhao Zhou, Xinming Xu, Yue Li, Rui Zhang, Zhiyan Yu, Xinmei Huang, Shufei Zang, Tiange Sun
Reprod Biol Endocrinol. 2024; 22: 2. Published online 2024 Jan 2. doi: 10.1186/s12958-023-01170-x
PMCID:
PMC10759696
AbstractArticlePDF–1.5M
5.
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis
Chang Cui, Kasturi Chakraborty, Xu Anna Tang, Guolin Zhou, Kelly Q. Schoenfelt, Kristen M. Becker, Alexandria Hoffman, Ya-Fang Chang, Ariane Blank, Catherine A. Reardon, Hilary A. Kenny, Tomas Vaisar, Ernst Lengyel, Geoffrey Greene, Lev Becker
Cell. Author manuscript; available in PMC 2023 Dec 11.
Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3163–3177.e21. Published online 2021 May 7. doi: 10.1016/j.cell.2021.04.016
PMCID:
PMC10712736
AbstractArticlePDF–3.3M
6.
Could the Oxidation of α1-Antitrypsin Prevent the Binding of Human Neutrophil Elastase in COVID-19 Patients?
Maura D’Amato, Monica Campagnoli, Paolo Iadarola, Paola Margherita Bignami, Marco Fumagalli, Laurent Roberto Chiarelli, Giovanni Stelitano, Federica Meloni, Pasquale Linciano, Simona Collina, Giampiero Pietrocola, Valentina Vertui, Anna Aliberti, Tommaso Fossali, Simona Viglio
Int J Mol Sci. 2023 Sep; 24(17): 13533. Published online 2023 Aug 31. doi: 10.3390/ijms241713533
PMCID:
PMC10488172
AbstractArticlePDF–3.6M
7.
Neutrophil elastase decreases SARS-CoV-2 spike protein binding to human bronchial epithelia by clipping ACE-2 ectodomain from the epithelial surface
Apparao B. Kummarapurugu, Adam M. Hawkridge, Jonathan Ma, Stephanie Osei, Rebecca K. Martin, Shuo Zheng, Judith A. Voynow
J Biol Chem. 2023 Jun; 299(6): 104820. Published online 2023 May 13. doi: 10.1016/j.jbc.2023.104820
PMCID:
PMC10181948
AbstractArticlePDF–2.0M
8.
The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing
Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai
Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140
PMCID:
PMC10164564
AbstractArticlePDF–3.8M
9.
Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells
Sara S. Oltra, Sara Colomo, Laura Sin, María Pérez-López, Sara Lázaro, Angela Molina-Crespo, Kyoung-Han Choi, David Ros-Pardo, Lidia Martínez, Saleta Morales, Cristina González-Paramos, Alba Orantes, Mario Soriano, Alberto Hernández, Ana Lluch, Federico Rojo, Joan Albanell, Paulino Gómez-Puertas, Jae-Kyun Ko, David Sarrió, Gema Moreno-Bueno
Cell Death Differ. 2023 May; 30(5): 1366–1381. Published online 2023 Mar 11. doi: 10.1038/s41418-023-01143-y
PMCID:
PMC10154425
AbstractArticlePDF–6.6M
10.
Paediatric autoimmune diseases with ELANE mutations associated with neutropenia
Dan Zhang, Gaixiu Su, Sheng Hao, Jianming Lai, Shunqiao Feng
Pediatr Rheumatol Online J. 2023; 21: 41. Published online 2023 Apr 28. doi: 10.1186/s12969-023-00824-9
PMCID:
PMC10142225
AbstractArticlePDF–1.2M
11.
The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against Moraxella catarrhalis
Justyna Roszkowiak, Siobhán McClean, Aleksandra M. Mirończuk, Daria Augustyniak
Int J Mol Sci. 2023 Apr; 24(7): 6607. Published online 2023 Apr 1. doi: 10.3390/ijms24076607
PMCID:
PMC10094786
AbstractArticlePDF–5.0M
12.
Cloaking the ACE2 receptor with salivary cationic proteins inhibits SARS-CoV-2 entry
Katsutoshi Yoshizato, Toshio Taira, Misako Sato-Matsubara, Shizuko Sekiguchi, Yoriko Yabunaka, Yukimi Kira, Tetsu Ohashi, Atsuko Daikoku, Ken Ofusa, Chiho Kadono, Daisuke Oikawa, Tsutomu Matsubara, Yu Nakagama, Yasutoshi Kido, Fuminori Tokunaga, Kazuo Ikeda, Akira Kaneko, Norifumi Kawada
J Biochem. 2022 Oct; 172(4): 205–216. Published online 2022 Jul 6. doi: 10.1093/jb/mvac054
PMCID:
PMC9278198
AbstractArticlePDF–1.5M
13.
Neutrophil Elastase Triggers the Release of Macrophage Extracellular Traps: Relevance to Cystic Fibrosis
Apparao B. Kummarapurugu, Shuo Zheng, Jonathan Ma, Shobha Ghosh, Adam Hawkridge, Judith A. Voynow
Am J Respir Cell Mol Biol. 2022 Jan; 66(1): 76–85. Published online 2021 Oct 1. doi: 10.1165/rcmb.2020-0410OC
PMCID:
PMC8803356
AbstractArticlePDF–1.2M
14.
Adenovirus Co-Opts Neutrophilic Inflammation to Enhance Transduction of Epithelial Cells
James M. Readler, Meghan R. Burke, Priyanka Sharma, Katherine J. D. A. Excoffon, Abimbola O. Kolawole
Viruses. 2022 Jan; 14(1): 13. Published online 2021 Dec 22. doi: 10.3390/v14010013
PMCID:
PMC8781108
AbstractArticlePDF–3.0M
15.
Reduced ELANE and SLPI expression compromises dental pulp cell activity
Kanokwan Sriwattanapong, Noppadol Sa‐Ard‐Iam, Lawan Boonprakong, Keskanya Subbalekha, Vorapat Trachoo, Narissara Suratannon, Thantrira Porntaveetus, Vorasuk Shotelersuk
Cell Prolif. 2021 Nov; 54(11): e13132. Published online 2021 Sep 27. doi: 10.1111/cpr.13132
PMCID:
PMC8560611
AbstractArticlePDF–2.0M
16.
Severe Pulmonary Arterial Hypertension Is Characterized by Increased Neutrophil Elastase and Relative Elafin Deficiency
Andrew J. Sweatt, Kazuya Miyagawa, Christopher J. Rhodes, Shalina Taylor, Patricia A. Del Rosario, Andrew Hsi, Francois Haddad, Edda Spiekerkoetter, Michal Bental-Roof, Richard D. Bland, Emilia M. Swietlik, Stefan Gräf, Martin R. Wilkins, Nicholas W. Morrell, Mark R. Nicolls, Marlene Rabinovitch, Roham T. Zamanian
Chest. 2021 Oct; 160(4): 1442–1458. Published online 2021 Jun 26. doi: 10.1016/j.chest.2021.06.028
PMCID:
PMC8546243
AbstractArticlePDF–1.8M
17.
Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases
Xiaojie Chu, Zehua Sun, Du-San Baek, Wei Li, John W. Mellors, Steven D. Shapiro, Dimiter S. Dimitrov
Int J Mol Sci. 2021 Oct; 22(20): 11136. Published online 2021 Oct 15. doi: 10.3390/ijms222011136
PMCID:
PMC8539514
AbstractArticlePDF–2.1M
18.
ELANE: an emerging lane to selective anticancer therapy
Boqiang Peng, Jiankun Hu, Xianghui Fu
Signal Transduct Target Ther. 2021; 6: 358. Published online 2021 Oct 1. doi: 10.1038/s41392-021-00766-2
PMCID:
PMC8486838
ArticlePDF–551K
19.
A possible pathogenic correlation between neutrophil elastase (NE) enzyme and inflammation in the pathogenesis of coronavirus disease 2019 (COVID-19)
Sajad Karampoor, Khashayar Hesamizadeh, Faezeh Maleki, Mohammad Farahmand, Hamid Zahednasab, Rasoul Mirzaei, Helene Banoun, Farhad Zamani, Marzieh Hajibaba, Alireza Tabibzadeh, Behnaz Bouzari, Mohammad-Navid Bastani, Azadeh Laali, Hossein Keyvani
Int Immunopharmacol. 2021 Nov; 100: 108137. Published online 2021 Sep 14. doi: 10.1016/j.intimp.2021.108137
PMCID:
PMC8437823
AbstractArticlePDF–5.2M
20.
Discrimination of Methionine Sulfoxide and Sulfone by Human Neutrophil Elastase
Darren Leahy, Cameron Grant, Alex Jackson, Alex Duff, Nicholas Tardiota, Jessica Van Haeften, Xingchen Chen, Jonathan M. Peake, Michael D. Kruppa, Eliot T. Smith, David A. Johnson, William B. Lott, Jonathan M. Harris
Molecules. 2021 Sep; 26(17): 5344. Published online 2021 Sep 2. doi: 10.3390/molecules26175344
PMCID:
PMC8434204
AbstractArticlePDF–2.1M

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