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Select item 100084871.

TIPE2 acts as a tumor suppressor and correlates with tumor microenvironment immunity in epithelial ovarian cancer

Shuai Xu, Xiaolin Gao, Jianqing Qiu, Fanzhen Hong, Fufeng Gao, Xia Wang, Shiqian Zhang

Aging (Albany NY) 2023 Feb 28; 15(4): 1052–1073. Published online 2023 Feb 17. doi: 10.18632/aging.204529

PMCID:: PMC10008487

Abstract Article PDF–2.3M

Select item 90959412.

TIPE2 May Target the Nrf2/HO-1 Pathway to Inhibit M1 Macrophage–Related Neutrophilic Inflammation in Asthma

Bingqing Shi, Yuqiu Hao, Wei Li, Hongna Dong, Mengting Xu, Peng Gao

Front Immunol. 2022; 13: 883885. Published online 2022 Apr 28. doi: 10.3389/fimmu.2022.883885

PMCID:: PMC9095941

Abstract Article PDF–14M

Select item 84431873.

TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity

Jiacheng Bi, Chen Cheng, Chaoyue Zheng, Chen Huang, Xiaohu Zheng, Xiaochun Wan, Youhai H. Chen, Zhigang Tian, Haoyu Sun

Sci Adv. 2021 Sep; 7(38): eabi6515. Published online 2021 Sep 15. doi: 10.1126/sciadv.abi6515

PMCID:: PMC8443187

Abstract Article PDF–1.3M

Select item 82050994.

TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTORC1 axis

Wen Li, Yulan Li, Yetong Guan, Yingxin Du, Mingsheng Zhao, Xiaotong Chen, Faliang Zhu, Chun Guo, Yufeng Jia, Yuan Li, Xiaoyu Wang, Xiaoyan Wang, Yongyu Shi, Qun Wang, Yan Li, Lining Zhang

Autophagy. 2021; 17(6): 1410–1425. Published online 2020 May 28. doi: 10.1080/15548627.2020.1761748

PMCID:: PMC8205099

Abstract Article PDF–19M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80403956.

A novel prognostic factor TIPE2 inhibits cell proliferation and promotes apoptosis in pancreatic ductal adenocarcinoma (PDAC)

Yuqi Sun, Shougen Cao, Zequn Li, Xiaodong Liu, Jinxiang Xu, Yulong Tian, Shuai Shen, Yanbing Zhou

Int J Med Sci. 2021; 18(9): 2051–2062. Published online 2021 Mar 11. doi: 10.7150/ijms.51497

PMCID:: PMC8040395

Abstract Article PDF–2.2M

Select item 78406917.

Tumor Necrosis Factor (TNF)-α-Induced Protein 8-like-2 (TIPE2) Inhibits Proliferation and Tumorigenesis in Breast Cancer Cells

Ke Wang, Yu Ren, Yang Liu, Jian Zhang, Jian-jun He

Oncol Res. 2017; 25(1): 55–63. Published online 2017 Jan 2. doi: 10.3727/096504016X14719078133320

PMCID:: PMC7840691

Abstract Article PDF–7.1M

Select item 78386678.

TIPE2 Overexpression Suppresses the Proliferation, Migration, and Invasion in Prostate Cancer Cells by Inhibiting PI3K/Akt Signaling Pathway

Qiang Lu, Zhe Liu, Zhuo Li, Jia Chen, Zhi Liao, Wan-rui Wu, Yuan-wei Li

Oncol Res. 2016; 24(5): 305–313. Published online 2016 Sep 14. doi: 10.3727/096504016X14666990347437

PMCID:: PMC7838667

Abstract Article PDF–7.1M

Select item 78386279.

TIPE2 Inhibits Hypoxia-Induced Wnt/β-Catenin Pathway Activation and EMT in Glioma Cells

Zhi-jun Liu, Hong-lin Liu, Hai-cun Zhou, Gui-cong Wang

Oncol Res. 2016; 24(4): 255–261. Published online 2016 Aug 10. doi: 10.3727/096504016X14666990347356

PMCID:: PMC7838627

Abstract Article PDF–3.6M

Select item 719316010.

Down‐regulation of anti‐inflammatory TIPE2 may aggravate adenoidal hypertrophy in children

Kun Gao, Yanzhong Li, Zhiyong Yue, Jie Han, Xuanchen Zhou, Xiaoting Wang

FEBS Open Bio. 2020 May; 10(5): 761–766. Published online 2020 Mar 22. doi: 10.1002/2211-5463.12821

PMCID:: PMC7193160

Abstract Article PDF–933K

Select item 704170511.

TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis

Dehong Yan, Jinghui Wang, Honghong Sun, Ali Zamani, Honglin Zhang, Weihong Chen, Aifa Tang, Qingguo Ruan, Xiaolu Yang, Youhai H. Chen, Xiaochun Wan

J Exp Med. 2020 Feb 3; 217(2): e20182005. Published online 2019 Oct 29. doi: 10.1084/jem.20182005

PMCID:: PMC7041705

Abstract Article PDF–3.0M

Select item 699557512.

TIPE2 Induced the Proliferation, Survival, and Migration of Lung Cancer Cells Through Modulation of Akt/mTOR/NF-κB Signaling Cascade

Devivasha Bordoloi, Kishore Banik, Ganesan Padmavathi, Rajesh Vikkurthi, Choudhary Harsha, Nand Kishor Roy, Anuj Kumar Singh, Javadi Monisha, Hong Wang, Alan Prem Kumar, Ajaikumar B Kunnumakkara

Biomolecules. 2019 Dec; 9(12): 836. Published online 2019 Dec 6. doi: 10.3390/biom9120836

PMCID:: PMC6995575

Abstract Article PDF–7.5M

Select item 637819813.

Tumour necrosis factor‐α‐induced protein 8‐like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells

Dong‐Dong Wu, Shi‐Yu Liu, Ying‐Ran Gao, Dan Lu, Ya Hong, Ya‐Ge Chen, Peng‐Zhen Dong, Da‐Yong Wang, Tao Li, Hui‐Min Li, Zhi‐Guang Ren, Jian‐Cheng Guo, Fei He, Xue‐Qun Ren, Shi‐Yong Sun, Shao‐Feng Duan, Xin‐Ying Ji

J Cell Mol Med. 2019 Mar; 23(3): 1698–1713. Published online 2019 Jan 13. doi: 10.1111/jcmm.14065

PMCID:: PMC6378198

Abstract Article PDF–8.1M

Select item 629942314.

Elevated Tumor Necrosis Factor-a-induced Protein 8-like 2 mRNA from Peripheral Blood Mononuclear Cells in Patients with Acute Ischemic Stroke

Yuan-Yuan Zhang, Na-Na Huang, Yan-Xin Zhao, Yan-Shuang Li, Dong Wang, Yu-Chen Fan, Xiao-Hong Li

Int J Med Sci. 2018; 15(14): 1713–1722. Published online 2018 Nov 22. doi: 10.7150/ijms.27817

PMCID:: PMC6299423

Abstract Article PDF–1.6M

Select item 611643515.

Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells

Wenming Liu, Yanyun Fan, Ying Shi, Zhenhe Lin, Xiaoxiao Huang, Wei Huang, Dongyan Shen, Zhongquan Qi

BMC Cancer. 2018; 18: 857. Published online 2018 Aug 29. doi: 10.1186/s12885-018-4761-3

PMCID:: PMC6116435

Abstract Article PDF–4.7M

Select item 607239616.

TIPE2 inhibits GC via regulation of cell proliferation, apoptosis and inflammation

Zhenhe Lin, Wenming Liu, Chuanxing Xiao, Yanyun Fan, Guohong Zhuang, Zhongquan Qi

Oncol Rep. 2018 Sep; 40(3): 1307–1316. Published online 2018 Jul 13. doi: 10.3892/or.2018.6576

PMCID:: PMC6072396

Abstract Article PDF–1.0M

Select item 592865617.

TIPE-2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3-kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian

Mol Med Rep. 2018 May; 17(5): 7017–7026. Published online 2018 Mar 20. doi: 10.3892/mmr.2018.8789

PMCID:: PMC5928656

Abstract Article PDF–2.5M

Select item 564532318.

TIPE2 negatively regulates mycoplasma pneumonia-triggered immune response via MAPK signaling pathway

Yuanyuan Zhang, Shufen Mei, Yunlian Zhou, Dehua Yang, Ting Pan, Zhimin Chen, Qingqing Wang

Sci Rep. 2017; 7: 13319. Published online 2017 Oct 17. doi: 10.1038/s41598-017-13825-y

PMCID:: PMC5645323

Abstract Article PDF–1.4M

Select item 557637619.

The decreased expression of TIPE2 protein in the decidua of patients with missed abortion and possible significance

Yingshuo Sun, Xiaoyan Wang, Yue Li, Han Sun, Lu Wan, Xishuang Wang, Lining Zhang, Zhenghui Fang, Zengtao Wei

Reprod Biol Endocrinol. 2017; 15: 68. Published online 2017 Aug 29. doi: 10.1186/s12958-017-0285-y

PMCID:: PMC5576376

Abstract Article PDF–1.1M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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