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Select item 113314091.

Loss of ADAR1 protein induces changes in small RNA landscape in hepatocytes

Kristina Roučová, Václav Vopálenský, Tomáš Mašek, Edgar del Llano, Jan Provazník, Jonathan J.M. Landry, Nayara Azevedo, Edvard Ehler, Vladimír Beneš, Martin Pospíšek

RNA. 2024 Sep; 30(9): 1164–1183. doi: 10.1261/rna.080097.124

PMCID:: PMC11331409

Abstract Article PDF–4.4M

Select item 113159292.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 112969143.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112816614.

Comparative Proteomics and Interactome Analysis of the SARS-CoV-2 Nucleocapsid Protein in Human and Bat Cell Lines

Stuart D. Armstrong, Covadonga Alonso, Isabel Garcia-Dorival

Viruses. 2024 Jul; 16(7): 1117. Published online 2024 Jul 11. doi: 10.3390/v16071117

PMCID:: PMC11281661

Abstract Article PDF–1.9M

Select item 112099355.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111140326.

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas

Bin Yang, Peishan Hu, Xihua Lin, Wei Han, Liyuan Zhu, Xiaochao Tan, Fei Ye, Guanzhou Wang, Fan Wu, Bin Yin, Zhaoshi Bao, Tao Jiang, Jiangang Yuan, Boqin Qiang, Xiaozhong Peng

Cell Mol Life Sci. 2015 Nov; 72(22): 4383–4397. Published online 2015 Jun 6. doi: 10.1007/s00018-015-1938-7

PMCID:: PMC11114032

Abstract Article PDF–3.0M

Select item 110724567.

The E3 ubiquitin ligase SMURF2 stabilizes RNA editase ADAR1p110 and promotes its adenosine-to-inosine (A-to-I) editing function

Praveen Koganti, Venkata Narasimha Kadali, Dhanoop Manikoth Ayyathan, Andrea Emanuelli, Biagio Paolini, Gal Levy-Cohen, Michael Blank

Cell Mol Life Sci. 2022 May; 79(5): 237. Published online 2022 Apr 11. doi: 10.1007/s00018-022-04272-8

PMCID:: PMC11072456

Abstract Article PDF–6.5M

Select item 110197528.

Multifaceted roles of RNA editing enzyme ADAR1 in innate immunity

Inga Jarmoskaite, Jin Billy Li

RNA. 2024 May; 30(5): 500–511. doi: 10.1261/rna.079953.124

PMCID:: PMC11019752

Abstract Article PDF–1.5M

Select item 109938569.

Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells

Kyle A. Cottrell, Sua Ryu, Jackson R. Pierce, Luisangely Soto Torres, Holly E. Bohlin, Angela M. Schab, Jason D. Weber

Cancer Res Commun. 2024 Apr; 4(4): 986–1003. Published online 2024 Apr 4. doi: 10.1158/2767-9764.CRC-23-0488

PMCID:: PMC10993856

Abstract Article PDF–13M

Select item 1096235610.

Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing

Maria Rivera, Haoran Zhang, Jessica Pham, Jane Isquith, Qingchen Jenny Zhou, Larisa Balaian, Roman Sasik, Sabina Enlund, Adam Mark, Wenxue Ma, Frida Holm, Kathleen M. Fisch, Dennis John Kuo, Catriona Jamieson, Qingfei Jiang

Cell Rep. Author manuscript; available in PMC 2024 Mar 25.

Published in final edited form as: Cell Rep. 2024 Feb 27; 43(2): 113704. Published online 2024 Jan 23. doi: 10.1016/j.celrep.2024.113704

PMCID:: PMC10962356

Abstract Article PDF–1.9M

Select item 1094246711.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 1087225412.

Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1

Agya Karki, Kristen B Campbell, Sukanya Mozumder, Andrew J. Fisher, Peter A. Beal

Biochemistry. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochemistry. 2024 Feb 6; 63(3): 282–293. Published online 2024 Jan 8. doi: 10.1021/acs.biochem.3c00405

PMCID:: PMC10872254

Abstract Article PDF–1.7M

Select item 1075809813.

ADAR1 protects pulmonary macrophages from sepsis-induced pyroptosis and lung injury through miR-21/A20 signaling

Xiaojun Zhao, Jiangang Xie, Chujun Duan, Linxiao Wang, Yi Si, Shanshou Liu, Qianmei Wang, Dan Wu, Yifan Wang, Wen Yin, Ran Zhuang, Junjie Li

Int J Biol Sci. 2024; 20(2): 464–485. Published online 2024 Jan 1. doi: 10.7150/ijbs.86424

PMCID:: PMC10758098

Abstract Article PDF–13M

Select item 1068174514.

ADAR1 links R-loop homeostasis to ATR activation in replication stress response

Biao Zhang, Yi Li, Jieyou Zhang, Yuejiao Wang, Can Liang, Ting Lu, Chunyong Zhang, Ling Liu, Yan Qin, Jiahuan He, Xiangnan Zhao, Jia Yu, Jihui Hao, Jie Yang, Mulin Jun Li, Zhi Yao, Shuai Ma, Hui Cheng, Tao Cheng, Lei Shi

Nucleic Acids Res. 2023 Nov 27; 51(21): 11668–11687. Published online 2023 Oct 13. doi: 10.1093/nar/gkad839

PMCID:: PMC10681745

Abstract Article PDF–3.8M

Select item 1046961215.

High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA

Liuyiqi Jiang, Mu Xiao, Qing-Qing Liao, Luqian Zheng, Chunyan Li, Yuemei Liu, Bing Yang, Aiming Ren, Chao Jiang, Xin-Hua Feng

mSystems. 2023 Jul-Aug; 8(4): e00135-23. Published online 2023 Jun 14. doi: 10.1128/msystems.00135-23

PMCID:: PMC10469612

Abstract Article PDF–4.0M

Select item 1046073216.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 1040462417.

RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing

Yanfang Xing, Taisuke Nakahama, Yuke Wu, Maal Inoue, Jung In Kim, Hiroyuki Todo, Toshiharu Shibuya, Yuki Kato, Yukio Kawahara

J Biol Chem. 2023 Jul; 299(7): 104840. Published online 2023 May 18. doi: 10.1016/j.jbc.2023.104840

PMCID:: PMC10404624

Abstract Article PDF–2.2M

Select item 1037396518.

Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer

Hao Yu, Kexin Bai, Yidong Cheng, Jiancheng Lv, Qiang Song, Haiwei Yang, Qiang Lu, Xiao Yang

Aging (Albany NY) 2023 Jul 15; 15(13): 6302–6330. Published online 2023 Jul 6. doi: 10.18632/aging.204853

PMCID:: PMC10373965

Abstract Article PDF–18M

Select item 1035820419.

ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma

Wendi Yang, Kehong Chen, Qian Yu, Rongxin Liao, Hengqiu He, Yuan Peng, Zhenzhou Yang, Xiaoyue Zhang

Cancer Med. 2023 Jul; 12(13): 14820–14832. Published online 2023 May 10. doi: 10.1002/cam4.6044

PMCID:: PMC10358204

Abstract Article PDF–20M

Select item 1033785420.

LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex

Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yoshifumi Kawamura, Naoki Goshima, Nobuyoshi Akimitsu, Tetsu Akiyama

PNAS Nexus. 2023 Jul; 2(7): pgad220. Published online 2023 Jul 4. doi: 10.1093/pnasnexus/pgad220

PMCID:: PMC10337854

Abstract Article PDF–851K

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