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Select item 111648961.

Suppression of smooth muscle cell inflammation by myocardin-related transcription factors involves inactivation of TANK-binding kinase 1

Elisabeth Bankell, Li Liu, Jennifer van der Horst, Catarina Rippe, Thomas A. Jepps, Bengt-Olof Nilsson, Karl Swärd

Sci Rep. 2024; 14: 13321. Published online 2024 Jun 10. doi: 10.1038/s41598-024-63901-3

PMCID:: PMC11164896

Abstract Article PDF–7.1M

Select item 93432782.

Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factors

Li Liu, Dmytro Kryvokhyzha, Catarina Rippe, Aishwarya Jacob, Andrea Borreguero-Muñoz, Karin G. Stenkula, Ola Hansson, Christopher W. J. Smith, Steven A. Fisher, Karl Swärd

Cell Mol Life Sci. 2022 Aug; 79(8): 459. Published online 2022 Aug 1. doi: 10.1007/s00018-022-04497-7

PMCID:: PMC9343278

Abstract Article PDF–9.1M

Select item 88270843.

Myocardin/microRNA-30a/Beclin1 signaling controls the phenotypic modulation of vascular smooth muscle cells by regulating autophagy

Danyang Shi, Jinhua Ding, Shouqiang Xie, Lei Huang, Hongmin Zhang, Xiaojie Chen, Xuejun Ren, Sa Zhou, Hongpeng He, Wenjian Ma, Tongcun Zhang, Nan Wang

Cell Death Dis. 2022 Feb; 13(2): 121. Published online 2022 Feb 8. doi: 10.1038/s41419-022-04588-0

Correction in:: Cell Death Dis. 2022 Apr; 13(4): 369.

PMCID:: PMC8827084

Abstract Article PDF–4.0M

Select item 87260164.

CARMN is an Evolutionarily Conserved Smooth Muscle Cell-specific LncRNA that Maintains Contractile Phenotype by Binding Myocardin

Kunzhe Dong, Jian Shen, Xiangqin He, Guoqing Hu, Liang Wang, Islam Osman, Kristopher M. Bunting, Rachael Dixon-Melvin, Zeqi Zheng, Hongbo Xin, Meixiang Xiang, Almira Vazdarjanova, David J. R. Fulton, Jiliang Zhou

Circulation. Author manuscript; available in PMC 2022 Dec 7.

Published in final edited form as: Circulation. 2021 Dec 7; 144(23): 1856–1875. Published online 2021 Oct 25. doi: 10.1161/CIRCULATIONAHA.121.055949

PMCID:: PMC8726016

Abstract Article PDF–5.0M

Select item 79256945.

Serum response factor‐cofactor interactions and their implications in disease

John Oloche Onuh, Hongyu Qiu

FEBS J. 2021 May; 288(10): 3120–3134. Published online 2020 Sep 12. doi: 10.1111/febs.15544

PMCID:: PMC7925694

Abstract Article PDF–594K

Select item 75237066.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 72742037.

Coronary Disease Associated Gene TCF21 Inhibits Smooth Muscle Cell Differentiation by Blocking the Myocardin-Serum Response Factor Pathway

Manabu Nagao, Qing Lyu, Quanyi Zhao, Robert C Wirka, Joetsaroop Bagga, Trieu Nguyen, Paul Cheng, Juyong Brian Kim, Milos Pjanic, Joseph M. Miano, Thomas Quertermous

Circ Res. Author manuscript; available in PMC 2021 Feb 14.

Published in final edited form as: Circ Res. 2020 Feb 14; 126(4): 517–529. Published online 2019 Dec 9. doi: 10.1161/CIRCRESAHA.119.315968

PMCID:: PMC7274203

Abstract Article PDF–2.3M

Select item 70622908.

The transcriptome of cervical ripening in human pregnancy before the onset of labor at term: identification of novel molecular functions involved in this process

Sonia S Hassan, Roberto Romero, Adi Tarca, Chia-Ling Nhan-Chang, Edi Vaisbuch, Offer Erez, Pooja Mittal, Juan Pedro Kusanovic, Shali Mazaki-Tovi, Lami Yeo, Sorin Draghici, Jung-Sun Kim, Niels Uldbjerg, Chong Jai Kim

J Matern Fetal Neonatal Med. Author manuscript; available in PMC 2020 Mar 9.

Published in final edited form as: J Matern Fetal Neonatal Med. 2009 Dec; 22(12): 1183–1193. doi: 10.3109/14767050903353216

PMCID:: PMC7062290

Abstract Article PDF–408K

Select item 69277549.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong

eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223

PMCID:: PMC6927754

Abstract Article PDF–5.1M

Select item 687730110.

Loss-of-function variants in myocardin cause congenital megabladder in humans and mice

Arjan C. Houweling, Glenda M. Beaman, Alex V. Postma, T. Blair Gainous, Klaske D. Lichtenbelt, Francesco Brancati, Filipa M. Lopes, Ingeborg van der Made, Abeltje M. Polstra, Michael L. Robinson, Kevin D. Wright, Jamie M. Ellingford, Ashley R. Jackson, Eline Overwater, Rita Genesio, Silvio Romano, Letizia Camerota, Emanuela D’Angelo, Elizabeth J. Meijers-Heijboer, Vincent M. Christoffels, Kirk M. McHugh, Brian L. Black, William G. Newman, Adrian S. Woolf, Esther E. Creemers

J Clin Invest. 2019 Dec 2; 129(12): 5374–5380. Published online 2019 Nov 4. doi: 10.1172/JCI128545

PMCID:: PMC6877301

Abstract Article PDF–8.0M

Select item 674264611.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 660421912.

Myocardin Is Involved in Mesothelial–Mesenchymal Transition of Human Pleural Mesothelial Cells

Torry Tucker, Yoshikazu Tsukasaki, Tsuyoshi Sakai, Shinya Mitsuhashi, Satoshi Komatsu, Ann Jeffers, Steven Idell, Mitsuo Ikebe

Am J Respir Cell Mol Biol. 2019 Jul; 61(1): 86–96. doi: 10.1165/rcmb.2018-0121OC

PMCID:: PMC6604219

Abstract Article PDF–2.7M

Select item 598461913.

Yes-associated protein inhibits transcription of myocardin and attenuates differentiation of vascular smooth muscle cell from cardiovascular progenitor cell lineage

Lunchang Wang, Ping Qiu, Jiao Jiao, Hiroyuki Hirai, Wei Xiong, Jifeng Zhang, Tianqing Zhu, Peter X. Ma, Y. Eugene Chen, Bo Yang

Stem Cells. Author manuscript; available in PMC 2018 Jun 2.

Published in final edited form as: Stem Cells. 2017 Feb; 35(2): 351–361. Published online 2016 Sep 20. doi: 10.1002/stem.2484

PMCID:: PMC5984619

Abstract Article PDF–932K

Select item 545398214.

VEGF-A Stimulates STAT3 Activity via Nitrosylation of Myocardin to Regulate the Expression of Vascular Smooth Muscle Cell Differentiation Markers

Xing Hua Liao, Yuan Xiang, Hui Li, De Liang Zheng, Yao Xu, Cheng Xi Yu, Jia Peng Li, Xiao Yu Zhang, Wei Bin Xing, Dong Sun Cao, Le Yuan Bao, Tong Cun Zhang

Sci Rep. 2017; 7: 2660. Published online 2017 Jun 1. doi: 10.1038/s41598-017-02907-6

PMCID:: PMC5453982

Abstract Article PDF–3.3M

Select item 485628515.

MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension

Sanghamitra Sahoo, Daniel N. Meijles, Imad Al Ghouleh, Manuj Tandon, Eugenia Cifuentes-Pagano, John Sembrat, Mauricio Rojas, Elena Goncharova, Patrick J. Pagano

PLoS One. 2016; 11(5): e0153780. Published online 2016 May 4. doi: 10.1371/journal.pone.0153780

PMCID:: PMC4856285

Abstract Article PDF–2.9M

Select item 465619816.

Angiotensin II Downregulates MicroRNA-145 to Regulate Kruppel-like Factor 4 and Myocardin Expression in Human Coronary Arterial Smooth Muscle Cells under High Glucose Conditions

Kou-Gi Shyu, Wen-Ping Cheng, Bao-Wei Wang

Mol Med. 2015; 21(1): 616–625. Prepublished online 2015 Jul 14. Published online 2015 Jul 14. doi: 10.2119/molmed.2015.00041

PMCID:: PMC4656198

Abstract Article PDF–3.4M

Select item 452812917.

STAT3 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin

Xing-Hua Liao, Nan Wang, Dong-Wei Zhao, De-Liang Zheng, Li Zheng, Wen-Jing Xing, Wen-Jian Ma, Le-Yuan Bao, Jian Dong, Tong-Cun Zhang

J Biol Chem. 2015 Aug 7; 290(32): 19641–19652. Published online 2015 Jun 22. doi: 10.1074/jbc.M114.630111

PMCID:: PMC4528129

Abstract Article PDF–3.0M

Select item 452623118.

Myocardin Family Members Drive Formation of Caveolae

Katarzyna K. Krawczyk, Ingrid Yao Mattisson, Mari Ekman, Nikolay Oskolkov, Rebecka Grantinge, Dorota Kotowska, Björn Olde, Ola Hansson, Sebastian Albinsson, Joseph M. Miano, Catarina Rippe, Karl Swärd

PLoS One. 2015; 10(8): e0133931. Published online 2015 Aug 5. doi: 10.1371/journal.pone.0133931

PMCID:: PMC4526231

Abstract Article PDF–6.6M

Select item 439012519.

Myocardin Regulates Vascular Smooth Muscle Cell Inflammatory Activation and Disease

Matthew Ackers-Johnson, Amarnath Talasila, Andrew P Sage, Xiaochun Long, Ilze Bot, Nicholas W Morrell, Martin R Bennett, Joseph M. Miano, Sanjay Sinha

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2016 Apr 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Apr; 35(4): 817–828. Published online 2015 Jan 22. doi: 10.1161/ATVBAHA.114.305218

PMCID:: PMC4390125

Abstract Article PDF–1.5M

Select item 426658820.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

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