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Select item 108349611.

WTAP-mediated m⁶A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis

Xueying An, Rongliang Wang, Zhongyang Lv, Wenshu Wu, Ziying Sun, Rui Wu, Wenjin Yan, Qing Jiang, Xingquan Xu

Exp Mol Med. 2024 Feb; 56(1): 156–167. Published online 2024 Jan 4. doi: 10.1038/s12276-023-01135-5

PMCID:: PMC10834961

Abstract Article PDF–8.9M

Select item 92585402.

Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis

Margo Tuerlings, Marcella van Hoolwerff, Jessica M van Bokkum, H Eka D Suchiman, Nico Lakenberg, Demiën Broekhuis, Rob G H H Nelissen, Yolande F M Ramos, Hailiang Mei, Davy Cats, Rodrigo Coutinho de Almeida, Ingrid Meulenbelt

Rheumatology (Oxford) 2022 Jul; 61(7): 3023–3032. Published online 2021 Nov 3. doi: 10.1093/rheumatology/keab826

PMCID:: PMC9258540

Abstract Article PDF–907K

Select item 84611613.

The Expressions of Dickkopf-Related Protein 1 and Frizzled-Related Protein Are Negatively Correlated to Local Inflammation and Osteoarthritis Severity

Xiaobin Huang, Leilei Zhong, Eefje van Helvoort, Floris Lafeber, Simon Mastbergen, Jan Hendriks, Janine N. Post, Marcel Karperien

Cartilage. 2021 Oct; 12(4): 496–504. Published online 2019 Apr 4. doi: 10.1177/1947603519841676

PMCID:: PMC8461161

Abstract Article PDF–815K

Select item 81091214.

Secreted frizzled-related protein 3 was genetically and functionally associated with developmental dysplasia of the hip

Renjie Xu, Fei Zhang, Junlan Lu, Kexin Wang, Peng Pan, Ye Sun, Yuxin Zhang

Aging (Albany NY) 2021 Apr 30; 13(8): 11281–11295. Published online 2021 Apr 4. doi: 10.18632/aging.202815

PMCID:: PMC8109121

Abstract Article PDF–1.7M

Select item 77898065.

FRZB as a key molecule in abdominal aortic aneurysm progression affecting vascular integrity

Chang-Kyu Oh, Yeji Ko, Jeong Jun Park, Hye Jin Heo, Junho Kang, Eun Jung Kwon, Ji Wan Kang, Yoonsung Lee, Kyungjae Myung, Jin Mo Kang, Dai Sik Ko, Yun Hak Kim

Biosci Rep. 2021 Jan 29; 41(1): BSR20203204. Published online 2021 Jan 6. doi: 10.1042/BSR20203204

PMCID:: PMC7789806

Abstract Article PDF–980K

Select item 75668816.

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat

Nat Metab. Author manuscript; available in PMC 2020 Dec 1.

Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z

PMCID:: PMC7566881

Abstract Article PDF–4.8M

Select item 72458717.

Leire Casas-Fraile, Frederique M. Cornelis, Domiziana Costamagna, Anabel Rico, Robin Duelen, Maurilio M. Sampaolesi, Adolfo López de Munain, Rik J. Lories, Amets Sáenz

Orphanet J Rare Dis. 2020; 15: 119. Published online 2020 May 24. doi: 10.1186/s13023-020-01372-1

PMCID:: PMC7245871

Abstract Article PDF–2.8M

Select item 71699838.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 61666829.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 608675610.

Decreased Local and Systemic Levels of sFRP3 protein in Osteosarcoma Patients

Dalibel Bravo, Ahmet Salduz, Kristen L. Shogren, Madison N. Okuno, James L. Herrick, Scott H. Okuno, Mario Galindo, Andre J. van Wijnen, Michael J. Yaszemski, Avudaiappan Maran

Gene. Author manuscript; available in PMC 2019 Oct 20.

Published in final edited form as: Gene. 2018 Oct 20; 674: 1–7. Published online 2018 Jun 19. doi: 10.1016/j.gene.2018.06.059

PMCID:: PMC6086756

Abstract Article PDF–598K

Select item 512473711.

Endogenous DKK1 and FRZB Regulate Chondrogenesis and Hypertrophy in Three-Dimensional Cultures of Human Chondrocytes and Human Mesenchymal Stem Cells

Leilei Zhong, Xiaobin Huang, Emilie Dooms Rodrigues, Jeroen C.H. Leijten, Theo Verrips, Mohamed El Khattabi, Marcel Karperien, Janine N. Post

Stem Cells Dev. 2016 Dec 1; 25(23): 1808–1817. Published online 2016 Dec 1. doi: 10.1089/scd.2016.0222

PMCID:: PMC5124737

Abstract Article PDF–828K

Select item 483807012.

Expression patterns of Wnt signaling component, secreted frizzled-related protein 3 in astrocytoma and glioblastoma

NIVES PEĆINA-ŠLAUS, ANJA KAFKA, ANA MARIA VAROŠANEC, LEON MARKOVIĆ, ŽELJKA KRSNIK, NIKO NJIRIĆ, GORAN MRAK

Mol Med Rep. 2016 May; 13(5): 4245–4251. Published online 2016 Mar 28. doi: 10.3892/mmr.2016.5061

PMCID:: PMC4838070

Abstract Article PDF–817K

Select item 476879313.

Secreted frizzled related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma

Julie J.G. Kephart, Rosanne G.J. Tiller, Lisa E.S. Crose, Katherine K. Slemmons, Po-Han Chen, Ashley R. Hinson, Rex C. Bentley, Jen-Tsan Ashley Chi, Corinne M. Linardic

Clin Cancer Res. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Clin Cancer Res. 2015 Nov 1; 21(21): 4868–4880. Published online 2015 Jun 12. doi: 10.1158/1078-0432.CCR-14-1797

PMCID:: PMC4768793

Abstract Article PDF–3.3M

Select item 468048514.

FRZB up-regulated in hepatocellular carcinoma bone metastasis

Jia Huang, Wenhao Hu, Xiangjin Lin, Xuanwei Wang, Ketao Jin

Int J Clin Exp Pathol. 2015; 8(10): 13353–13359. Published online 2015 Oct 1.

PMCID:: PMC4680485

Abstract Article PDF–749K

Select item 454583115.

Secreted Frizzled Related Protein 3 in Chronic Heart Failure: Analysis from the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA)

Erik Tandberg Askevold, Lars Gullestad, Ståle Nymo, John Kjekshus, Arne Yndestad, Roberto Latini, John G. F. Cleland, John J. V. McMurray, Pål Aukrust, Thor Ueland

PLoS One. 2015; 10(8): e0133970. Published online 2015 Aug 19. doi: 10.1371/journal.pone.0133970

PMCID:: PMC4545831

Abstract Article PDF–1.2M

Select item 446698316.

FRZB up-regulation is correlated with hepatic metastasis and poor prognosis in colon carcinoma patients with hepatic metastasis

Yanping Shen, Fang Zhang, Huanrong Lan, Ke Chen, Qi Zhang, Guoming Xie, Lisong Teng, Ketao Jin

Int J Clin Exp Pathol. 2015; 8(4): 4083–4090. Published online 2015 Apr 1.

PMCID:: PMC4466983

Abstract Article PDF–817K

Select item 441288517.

Large-Scale Analysis of Association Between GDF5 and FRZB Variants and Osteoarthritis of the Hip, Knee, and Hand

Evangelos Evangelou, Kay Chapman, Ingrid Meulenbelt, Fotini B. Karassa, John Loughlin, Andrew Carr, Michael Doherty, Sally Doherty, Juan J. Gómez-Reino, Antonio Gonzalez, Bjarni V. Halldorsson, Valdimar B. Hauksson, Albert Hofman, Deborah J. Hart, Shiro Ikegawa, Thorvaldur Ingvarsson, Qing Jiang, Ingileif Jonsdottir, Helgi Jonsson, Hanneke J. M. Kerkhof, Margreet Kloppenburg, Nancy E. Lane, Jia Li, Rik J. Lories, Joyce B. J. van Meurs, Annu Näkki, Michael C. Nevitt, Julio Rodriguez-Lopez, Dongquan Shi, P. Eline Slagboom, Kari Stefansson, Aspasia Tsezou, Gillian A. Wallis, Christopher M. Watson, Tim D. Spector, Andre G. Uitterlinden, Ana M. Valdes, John P. A. Ioannidis

Arthritis Rheum. Author manuscript; available in PMC 2015 Apr 29.

Published in final edited form as: Arthritis Rheum. 2009 Jun; 60(6): 1710–1721. doi: 10.1002/art.24524

PMCID:: PMC4412885

Abstract Article PDF–656K

Select item 397882518.

GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors

Jeroen CH Leijten, Steffan D Bos, Ellie BM Landman, Nicole Georgi, Holger Jahr, Ingrid Meulenbelt, Janine N Post, Clemens A van Blitterswijk, Marcel Karperien

Arthritis Res Ther. 2013; 15(5): R126. Published online 2013 Sep 19. doi: 10.1186/ar4306

PMCID:: PMC3978825

Abstract Article PDF–1.0M

Select item 397072919.

Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans

M-H Jang, Y Kitabatake, E Kang, H Jun, MV Pletnikov, KM Christian, R Hen, S Lucae, EB Binder, H Song, G-I Ming

Mol Psychiatry. Author manuscript; available in PMC 2014 Mar 31.

Published in final edited form as: Mol Psychiatry. 2013 Sep; 18(9): 957–958. Published online 2012 Dec 4. doi: 10.1038/mp.2012.158

PMCID:: PMC3970729

Article PDF–599K

Select item 392561020.

Promoter Methylation of SFRP3 Is Frequent in Hepatocellular Carcinoma

Ya-Wen Lin, Yu-Lueng Shih, Gi-Shih Lien, Fat-Moon Suk, Chung-Bao Hsieh, Ming-De Yan

Dis Markers. 2014; 2014: 351863. Published online 2014 Jan 21. doi: 10.1155/2014/351863

PMCID:: PMC3925610

Abstract Article PDF–1.0M

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