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Items: 1 to 20 of 30

1.
Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation
Gerry A. Shipman, Reinnier Padilla, Cynthia Horth, Bo Hu, Eric Bareke, Francisca N. Vitorino, Joanna M. Gongora, Benjamin A. Garcia, Chao Lu, Jacek Majewski
Genome Biol. 2024; 25: 263. Published online 2024 Oct 10. doi: 10.1186/s13059-024-03415-3
PMCID:
PMC11465688
AbstractArticlePDF–6.0M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
ASH1L contributes to oocyte apoptosis by regulating DNA damage
Tuo Zhang, Tianhe Ren, Huan Lin, Yuntong Tong, Jixian Zhang, Jie Nie, Yingjie Zhu, Yiting Wang, Bangming Jin, Chunlin Zhang, Tengxiang Chen, Meina He
Am J Physiol Cell Physiol. 2022 Oct 1; 323(4): C1264–C1273. Published online 2022 Sep 12. doi: 10.1152/ajpcell.00196.2022
PMCID:
PMC9576165
AbstractArticle
4.
Neural Hyperactivity Is a Core Pathophysiological Change Induced by Deletion of a High Autism Risk Gene Ash1L in the Mouse Brain
Yuen Gao, Mohammad B. Aljazi, Jin He
Front Behav Neurosci. 2022; 16: 873466. Published online 2022 Apr 5. doi: 10.3389/fnbeh.2022.873466
PMCID:
PMC9016273
AbstractArticlePDF–3.3M
5.
Deficiency of autism risk factor ASH1L in prefrontal cortex induces epigenetic aberrations and seizures
Luye Qin, Jamal B. Williams, Tao Tan, Tiaotiao Liu, Qing Cao, Kaijie Ma, Zhen Yan
Nat Commun. 2021; 12: 6589. Published online 2021 Nov 15. doi: 10.1038/s41467-021-26972-8
PMCID:
PMC8593046
AbstractArticlePDF–2.8M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors
Yuen Gao, Natalia Duque-Wilckens, Mohammad B. Aljazi, Yan Wu, Adam J. Moeser, George I. Mias, Alfred J. Robison, Jin He
Commun Biol. 2021; 4: 756. Published online 2021 Jun 18. doi: 10.1038/s42003-021-02282-z
PMCID:
PMC8213741
AbstractArticlePDF–3.2M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
Novel role of ASH1L histone methyltransferase in anaplastic thyroid carcinoma
Bin Xu, Tingting Qin, Jingcheng Yu, Thomas J. Giordano, Maureen A. Sartor, Ronald J. Koenig
J Biol Chem. 2020 Jun 26; 295(26): 8834–8845. Published online 2020 May 12. doi: 10.1074/jbc.RA120.013530
PMCID:
PMC7324504
AbstractArticlePDF–2.0M
10.
The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression
Ilaria Castiglioni, Roberta Caccia, Jose Manuel Garcia-Manteiga, Giulia Ferri, Giuseppina Caretti, Ivan Molineris, Kenichi Nishioka, Davide Gabellini
Nat Commun. 2018; 9: 5026. Published online 2018 Nov 28. doi: 10.1038/s41467-018-07313-8
PMCID:
PMC6262021
AbstractArticlePDF–2.7M
11.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
12.
MIR142 loss-of-function mutations derepress ASH1L to increase HOXA gene expression and promote leukemogenesis
Maria C. Trissal, Terrence N. Wong, Juo-Chin Yao, Rahul Ramaswamy, Iris Kuo, Jack Baty, Yaping Sun, Gloria Jih, Nishi Parikh, Melissa M. Berrien-Elliott, Todd A. Fehniger, Timothy J. Ley, Ivan Maillard, Pavan R. Reddy, Daniel C. Link
Cancer Res. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Cancer Res. 2018 Jul 1; 78(13): 3510–3521. Published online 2018 May 3. doi: 10.1158/0008-5472.CAN-17-3592
PMCID:
PMC6030481
AbstractArticlePDF–1.8M
13.
Ash1l and lnc-Smad3 coordinate Smad3 locus accessibility to modulate iTreg polarization and T cell autoimmunity
Meng Xia, Juan Liu, Shuxun Liu, Kun Chen, Hongyu Lin, Minghong Jiang, Xiaoqing Xu, Yiquan Xue, Wei Liu, Yan Gu, Xiang Zhang, Zhiqing Li, Lin Yi, Youcun Qian, Chen Zhou, Ru Li, Xuan Zhang, Zhanguo Li, Xuetao Cao
Nat Commun. 2017; 8: 15818. Published online 2017 Jun 9. doi: 10.1038/ncomms15818
PMCID:
PMC5472765
AbstractArticlePDF–2.0M
14.
The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice
Gang Li, Zhisheng Ye, Cheng Shi, Ling Sun, Min Han, Yuan Zhuang, Tian Xu, Shimin Zhao, Xiaohui Wu
Sci Rep. 2017; 7: 45401. Published online 2017 Apr 4. doi: 10.1038/srep45401
PMCID:
PMC5379632
AbstractArticlePDF–2.3M
15.
Histone methyltransferase Ash1L mediates activity-dependent repression of neurexin-1α
Τao Zhu, Chen Liang, Dongdong Li, Miaomiao Tian, Sanxiong Liu, Guanjun Gao, Ji-Song Guan
Sci Rep. 2016; 6: 26597. Published online 2016 May 27. doi: 10.1038/srep26597
PMCID:
PMC4882582
AbstractArticlePDF–2.1M
16.
The Histone Methyltransferase Gene Absent, Small, or Homeotic Discs-1 Like Is Required for Normal Hox Gene Expression and Fertility in Mice
Michelle L. Brinkmeier, Krista A. Geister, Morgan Jones, Meriam Waqas, Ivan Maillard, Sally A. Camper
Biol Reprod. 2015 Nov; 93(5): 121. Published online 2015 Sep 2. doi: 10.1095/biolreprod.115.131516
PMCID:
PMC4712006
AbstractArticlePDF–3.3M
17.
Reprogramming of Polycomb-Mediated Gene Silencing in Embryonic Stem Cells by the miR-290 Family and the Methyltransferase Ash1l
Chryssa Kanellopoulou, Timothy Gilpatrick, Gokhul Kilaru, Patrick Burr, Cuong K. Nguyen, Aaron Morawski, Michael J. Lenardo, Stefan A. Muljo
Stem Cell Reports. 2015 Dec 8; 5(6): 971–978. Published online 2015 Nov 5. doi: 10.1016/j.stemcr.2015.10.001
PMCID:
PMC4682067
AbstractArticlePDF–1.9M
18.
Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells
Morgan Jones, Jennifer Chase, Michelle Brinkmeier, Jing Xu, Daniel N. Weinberg, Julien Schira, Ann Friedman, Sami Malek, Jolanta Grembecka, Tomasz Cierpicki, Yali Dou, Sally A. Camper, Ivan Maillard
J Clin Invest. 2015 May 1; 125(5): 2007–2020. Published online 2015 Apr 13. doi: 10.1172/JCI78124
PMCID:
PMC4463197
AbstractArticlePDF–2.9M
19.
Histone H2A Ubiquitination Inhibits the Enzymatic Activity of H3 Lysine 36 Methyltransferases
Gang Yuan, Ben Ma, Wen Yuan, Zhuqiang Zhang, Ping Chen, Xiaojun Ding, Li Feng, Xiaohua Shen, She Chen, Guohong Li, Bing Zhu
J Biol Chem. 2013 Oct 25; 288(43): 30832–30842. Published online 2013 Sep 9. doi: 10.1074/jbc.M113.475996
PMCID:
PMC3829398
AbstractArticlePDF–2.6M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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