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Select item 106360631.

Progesterone activation of β₁-containing BK channels involves two binding sites

Kelsey C. North, Andrew A. Shaw, Anna N. Bukiya, Alex M. Dopico

Nat Commun. 2023; 14: 7248. Published online 2023 Nov 9. doi: 10.1038/s41467-023-42827-w

PMCID:: PMC10636063

Abstract Article PDF–2.7M

Select item 100270902.

Interspecies and regional variability of alcohol action on large cerebral arteries: regulation by KCNMB1 proteins

Steven Mysiewicz, Kelsey C. North, Luiz Moreira, Jr., Schyler J. Odum, Anna N. Bukiya, Alex M. Dopico

Am J Physiol Regul Integr Comp Physiol. 2023 Apr 1; 324(4): R480–R496. Published online 2023 Jan 30. doi: 10.1152/ajpregu.00103.2022

PMCID:: PMC10027090

Abstract Article

Select item 71768883.

Knockout of AKAP150 improves impaired BK channel‐mediated vascular dysfunction through the Akt/GSK3β signalling pathway in diabetes mellitus

Yan‐Rong Zhu, Xiao‐Xin Jiang, Peng Ye, Zhi‐Mei Wang, Yaguo Zheng, Zhizhong Liu, Shao‐Liang Chen, Dai‐Min Zhang

J Cell Mol Med. 2020 Apr; 24(8): 4716–4725. Published online 2020 Mar 12. doi: 10.1111/jcmm.15143

PMCID:: PMC7176888

Abstract Article PDF–1.1M

Select item 61396564.

β1-Subunit of the calcium-sensitive potassium channel modulates the pulmonary vascular smooth muscle cell response to hypoxia

Elizabeth A. Barnes, Lori Lee, Shayna L. Barnes, Robert Brenner, Cristina M. Alvira, David N. Cornfield

Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1; 315(2): L265–L275. Published online 2018 Apr 12. doi: 10.1152/ajplung.00060.2018

PMCID:: PMC6139656

Abstract Article

Select item 58122745.

Membrane depolarization activates BK channels through ROCK-mediated β1 subunit surface trafficking to limit vasoconstriction

M. Dennis Leo, Xue Zhai, Padmapriya Muralidharan, Korah P. Kuruvilla, Simon Bulley, Frederick A. Boop, Jonathan H. Jaggar

Sci Signal. Author manuscript; available in PMC 2018 May 9.

Published in final edited form as: Sci Signal. 2017 May 9; 10(478): eaah5417. Published online 2017 May 9. doi: 10.1126/scisignal.aah5417

PMCID:: PMC5812274

Abstract Article PDF–1.2M

Select item 52746336.

Distinct mechanisms underlying cholesterol protection against alcohol-induced BK channel inhibition and resulting vasoconstriction

Shivantika Bisen, Olga Seleverstov, Jitendra Belani, Scott Rychnovsky, Alex M. Dopico, Anna N. Bukiya

Biochim Biophys Acta. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Biochim Biophys Acta. 2016 Nov; 1861(11): 1756–1766. Published online 2016 Aug 24. doi: 10.1016/j.bbalip.2016.08.013

PMCID:: PMC5274633

Abstract Article PDF–1.0M

Select item 50072917.

High-fat diet-induced obesity alters nitric oxide-mediated neuromuscular transmission and smooth muscle excitability in the mouse distal colon

Yogesh Bhattarai, David Fried, Brian Gulbransen, Mark Kadrofske, Roxanne Fernandes, Hui Xu, James Galligan

Am J Physiol Gastrointest Liver Physiol. 2016 Aug 1; 311(2): G210–G220. Published online 2016 Jun 10. doi: 10.1152/ajpgi.00085.2016

PMCID:: PMC5007291

Abstract Article

Select item 47435388.

BK channel β1-subunit deficiency exacerbates vascular fibrosis and remodeling but does not promote hypertension in high fat fed obesity in mice

Hui Xu, Hannah Garver, Roxanne Fernandes, Jeremiah T Phelps, Jack J Harkema, James J Galligan, Gregory D Fink

J Hypertens. Author manuscript; available in PMC 2016 Feb 5.

Published in final edited form as: J Hypertens. 2015 Aug; 33(8): 1611–1623. doi: 10.1097/HJH.0000000000000590

PMCID:: PMC4743538

Abstract Article PDF–3.2M

Select item 43707369.

Ion Channel Expression in the Developing Enteric Nervous System

Caroline S. Hirst, Jaime P. P. Foong, Lincon A. Stamp, Emily Fegan, Stephan Dent, Edward C. Cooper, Alan E. Lomax, Colin R. Anderson, Joel C. Bornstein, Heather M. Young, Sonja J. McKeown

PLoS One. 2015; 10(3): e0123436. Published online 2015 Mar 23. doi: 10.1371/journal.pone.0123436

PMCID:: PMC4370736

Abstract Article PDF–9.5M

Select item 432784410.

Vascular BK channel deficiency exacerbates organ damage and mortality in endotoxemic mice

Hui Xu, Youping Wang, Hannah Garver, James J. Galligan, Gregory D. Fink

J Cardiovasc Pharmacol. Author manuscript; available in PMC 2015 Feb 13.

Published in final edited form as: J Cardiovasc Pharmacol. 2012 Mar; 59(3): 207–214. doi: 10.1097/FJC.0b013e31823b493b

PMCID:: PMC4327844

Abstract Article PDF–1.9M

Select item 408093811.

Smooth muscle BK channel activity influences blood pressure independent of vascular tone in mice

Gregor Sachse, Jörg Faulhaber, Anika Seniuk, Heimo Ehmke, Olaf Pongs

J Physiol. 2014 Jun 15; 592(Pt 12): 2563–2574. Published online 2014 Mar 31. doi: 10.1113/jphysiol.2014.272880

PMCID:: PMC4080938

Abstract Article PDF–987K

Select item 408027912.

Transcriptional profiling reveals ductus arteriosus-specific genes that regulate vascular tone

Elaine L. Shelton, Gerren Ector, Cristi L. Galindo, Christopher W. Hooper, Naoko Brown, Irene Wilkerson, Elise R. Pfaltzgraff, Bibhash C. Paria, Robert B. Cotton, Jason Z. Stoller, Jeff Reese

Physiol Genomics. 2014 Jul 1; 46(13): 457–466. Published online 2014 May 1. doi: 10.1152/physiolgenomics.00171.2013

PMCID:: PMC4080279

Abstract Article

Select item 403619813.

Regulation of Large Conductance Ca²⁺-activated K⁺ (BK) Channel β1 Subunit Expression by Muscle RING Finger Protein 1 in Diabetic Vessels

Fu Yi, Huan Wang, Qiang Chai, Xiaoli Wang, Win-Kuang Shen, Monte S. Willis, Hon-Chi Lee, Tong Lu

J Biol Chem. 2014 Apr 11; 289(15): 10853–10864. Published online 2014 Feb 25. doi: 10.1074/jbc.M113.520940

PMCID:: PMC4036198

Abstract Article PDF–2.1M

Select item 395411714.

AKAP150 Contributes to Enhanced Vascular Tone by Facilitating BK_Ca Channel Remodeling in Hyperglycemia and Diabetes

Matthew A. Nystoriak, Madeline Nieves-Cintrón, Patrick J. Nygren, Simon A. Hinke, C. Blake Nichols, Chao-Yin Chen, Jose L. Puglisi, Leighton T. Izu, Donald M. Bers, Mark L. Dell’Acqua, John D. Scott, Luis F. Santana, Manuel F. Navedo

Circ Res. Author manuscript; available in PMC 2015 Feb 14.

Published in final edited form as: Circ Res. 2014 Feb 14; 114(4): 607–615. Published online 2013 Dec 9. doi: 10.1161/CIRCRESAHA.114.302168

PMCID:: PMC3954117

Abstract Article PDF–3.1M

Select item 379137915.

Functional effects of KCNQ K⁺ channels in airway smooth muscle

Alexey I. Evseev, Iurii Semenov, Crystal R. Archer, Jorge L. Medina, Peter H. Dube, Mark S. Shapiro, Robert Brenner

Front Physiol. 2013; 4: 277. Published online 2013 Oct 7. doi: 10.3389/fphys.2013.00277

PMCID:: PMC3791379

Abstract Article PDF–2.5M

Select item 368072516.

DiBAC₄(3) hits a “sweet spot” for the activation of arterial large-conductance Ca²⁺-activated potassium channels independently of the β₁-subunit

Fabiana S. Scornik, Ronald S. Bucciero, Yuesheng Wu, Elisabet Selga, Cristina Bosch Calero, Ramon Brugada, Guillermo J. Pérez

Am J Physiol Heart Circ Physiol. 2013 Jun 1; 304(11): H1471–H1482. Published online 2013 Mar 29. doi: 10.1152/ajpheart.00939.2012

PMCID:: PMC3680725

Abstract Article

Select item 363382217.

Reduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice

Elaine Wan, Jared S. Kushner, Sergey Zakharov, Xiao-wei Nui, Neelesh Chudasama, Christopher Kelly, Marc Waase, Darshan Doshi, Guoxia Liu, Shinichi Iwata, Takayuki Shiomi, Alexander Katchman, Jeanine D'Armiento, Shunichi Homma, Steven O. Marx

FASEB J. 2013 May; 27(5): 1859–1867. doi: 10.1096/fj.12-223511