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Select item 114923211.

Gene expression and characterization of clonally derived murine embryonic brown and brite adipocytes

Cristina Velez‐delValle, Claudia Patricia Hernandez‐Mosqueira, Lidia Itzel Castro‐Rodriguez, Alfredo Vazquez‐Sandoval, Meytha Marsch‐Moreno, Walid Kuri‐Harcuch

FEBS Open Bio. 2024 Sep; 14(9): 1503–1525. Published online 2024 Jul 7. doi: 10.1002/2211-5463.13861

PMCID:: PMC11492321

Abstract Article PDF–3.6M

Select item 113524272.

Activation of VGLL4 Suppresses Cardiomyocyte Maturational Hypertrophic Growth

Aaron Farley, Yunan Gao, Yan Sun, Sylvia Zohrabian, William T. Pu, Zhiqiang Lin

Cells. 2024 Aug; 13(16): 1342. Published online 2024 Aug 13. doi: 10.3390/cells13161342

PMCID:: PMC11352427

Abstract Article PDF–6.2M

Select item 112138713.

A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain

Sofia Madsen, Ana C. Delgado, Christelle Cadilhac, Vanille Maillard, Fabrice Battiston, Carla Marie Igelbüscher, Simon De Neck, Elia Magrinelli, Denis Jabaudon, Ludovic Telley, Fiona Doetsch, Marlen Knobloch

Nat Commun. 2024; 15: 5489. Published online 2024 Jun 28. doi: 10.1038/s41467-024-49449-w

PMCID:: PMC11213871

Abstract Article PDF–7.1M

Select item 110884654.

SLC25A28 Overexpression Promotes Adipogenesis by Reducing ATGL

Hua Guan, Lin Xiao, Kaikai Hao, Qiang Zhang, Dongliang Wu, Zhanyi Geng, Bowen Duan, Hui Dai, Ruifen Xu, Xuyang Feng

J Diabetes Res. 2024; 2024: 5511454. Published online 2024 May 4. doi: 10.1155/2024/5511454

PMCID:: PMC11088465

Abstract Article PDF–1.9M

Select item 110211975.

Glucose controls lipolysis through Golgi PtdIns4P-mediated regulation of ATGL

Lianggong Ding, Florian Huwyler, Fen Long, Wu Yang, Jonas Binz, Kendra Wernlé, Matthias Pfister, Manuel Klug, Miroslav Balaz, Barbara Ukropcova, Jozef Ukropec, Chunyan Wu, Tongtong Wang, Min Gao, Pierre-Alain Clavien, Philipp Dutkowski, Mark W. Tibbitt, Christian Wolfrum

Nat Cell Biol. 2024; 26(4): 552–566. Published online 2024 Apr 1. doi: 10.1038/s41556-024-01386-y

PMCID:: PMC11021197

Abstract Article PDF–31M

Select item 108666536.

Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice

Nabil E. Boutagy, Ana Gamez-Mendez, Joseph W.M. Fowler, Hanming Zhang, Bal K. Chaube, Enric Esplugues, Andrew Kuo, Sungwoon Lee, Daiki Horikami, Jiasheng Zhang, Kathryn M. Citrin, Abhishek K. Singh, Brian G. Coon, Monica Y. Lee, Yajaira Suarez, Carlos Fernandez-Hernando, William C. Sessa

J Clin Invest. 2024 Feb 15; 134(4): e170453. Published online 2024 Jan 4. doi: 10.1172/JCI170453

PMCID:: PMC10866653

Abstract Article PDF–6.2M

Select item 108509717.

Renal tubule-specific Atgl deletion links kidney lipid metabolism to glucagon-like peptide 1 and insulin secretion independent of renal inflammation or lipotoxicity

Maria F. Fernandes, Juan J. Aristizabal-Henao, Phillip M. Marvyn, Iman M'Hiri, Meghan A. Wiens, Monica Hoang, Manuel Sebastian, Renato Nachbar, Philippe St-Pierre, Kalsha Diaguarachchige De Silva, Geoffrey A. Wood, Jamie W. Joseph, Christine A. Doucette, André Marette, Ken D. Stark, Robin E. Duncan

Mol Metab. 2024 Mar; 81: 101887. Published online 2024 Jan 26. doi: 10.1016/j.molmet.2024.101887

PMCID:: PMC10850971

Abstract Article PDF–2.5M

Select item 108396918.

Acute activation of adipocyte lipolysis reveals dynamic lipid remodeling of the hepatic lipidome

Sicheng Zhang, Kevin J. Williams, Amandine Verlande-Ferrero, Alvin P. Chan, Gino B. Su, Erin E. Kershaw, James E. Cox, John Alan Maschek, Suzanne N. Shapira, Heather R. Christofk, Thomas Q. de Aguiar Vallim, Selma Masri, Claudio J. Villanueva

J Lipid Res. 2024 Feb; 65(2): 100434. Published online 2023 Aug 26. doi: 10.1016/j.jlr.2023.100434

PMCID:: PMC10839691

Abstract Article PDF–7.4M

Select item 108285869.

Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58

Natalia Kulminskaya, Carlos Francisco Rodriguez Gamez, Peter Hofer, Ines Kathrin Cerk, Noopur Dubey, Roland Viertlmayr, Theo Sagmeister, Tea Pavkov-Keller, Rudolf Zechner, Monika Oberer

J Lipid Res. 2024 Jan; 65(1): 100491. Published online 2023 Dec 20. doi: 10.1016/j.jlr.2023.100491

Correction in:: J Lipid Res. 2024 Aug; 65(8): 100613.

PMCID:: PMC10828586

Abstract Article PDF–4.1M

Select item 1080922310.

Epinephrine inhibits PI3Kα via the Hippo kinases

Ting-Yu Lin, Shakti Ramsamooj, Tiffany Perrier, Katarina Liberatore, Louise Lantier, Neil Vasan, Kannan Karukurichi, Seo-Kyoung Hwang, Edward A. Kesicki, Edward R. Kastenhuber, Thorsten Wiederhold, Tomer M. Yaron, Emily M. Huntsman, Mengmeng Zhu, Yilun Ma, Marcia N. Paddock, Guoan Zhang, Benjamin D. Hopkins, Owen McGuinness, Robert E. Schwartz, Baran A. Ersoy, Lewis C. Cantley, Jared L. Johnson, Marcus D. Goncalves

Cell Rep. Author manuscript; available in PMC 2024 Jan 25.

Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113535. Published online 2023 Dec 4. doi: 10.1016/j.celrep.2023.113535

PMCID:: PMC10809223

Abstract Article PDF–2.3M

Select item 1059086611.

Sympathetic overdrive and unrestrained adipose lipolysis drive alcohol-induced hepatic steatosis in rodents

Chunxue Zhou, Henry H. Ruiz, Li Ling, Giulia Maurizi, Kenichi Sakamoto, Claudia G. Liberini, Ling Wang, Adrien Stanley, Hale E. Egritag, Sofia M. Sanz, Claudia Lindtner, Mary A. Butera, Christoph Buettner

Mol Metab. 2023 Dec; 78: 101813. Published online 2023 Sep 29. doi: 10.1016/j.molmet.2023.101813

PMCID:: PMC10590866

Abstract Article PDF–2.5M

Select item 1040697612.

PNPLA2 mobilizes retinyl esters from retinosomes and promotes the generation of 11-cis-retinal in the visual cycle

Miwa Hara, Wenjing Wu, Volha V. Malechka, Yusuke Takahashi, Jian-Xing Ma, Gennadiy Moiseyev

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112091. Published online 2023 Feb 8. doi: 10.1016/j.celrep.2023.112091

PMCID:: PMC10406976

Abstract Article PDF–2.1M

Select item 1039867213.

PRMT5 links lipid metabolism to contractile function of skeletal muscles

Kun Ho Kim, Zhihao Jia, Madigan Snyder, Jingjuan Chen, Jiamin Qiu, Stephanie N Oprescu, Xiyue Chen, Sabriya A Syed, Feng Yue, Bruno T Roseguini, Anthony N Imbalzano, Changdeng Hu, Shihuan Kuang

EMBO Rep. 2023 Aug; 24(8): e57306. Published online 2023 Jun 19. doi: 10.15252/embr.202357306

PMCID:: PMC10398672

Abstract Article PDF–4.0M

Select item 1024886914.

Sympathetic tone dictates the impact of lipolysis on FABP4 secretion

Kacey J. Prentice, Alexandra Lee, Paulina Cedillo, Karen E. Inouye, Meric Erikci Ertunc, Jillian K. Riveros, Grace Yankun Lee, Gökhan S. Hotamisligil

J Lipid Res. 2023 Jun; 64(6): 100386. Published online 2023 May 10. doi: 10.1016/j.jlr.2023.100386

PMCID:: PMC10248869

Abstract Article PDF–1.2M

Select item 1023321015.

Ablation of pigment epithelium-derived factor receptor (PEDF-R/Pnpla2) causes photoreceptor degeneration

Alexandra Bernardo-Colón, Lijin Dong, Mones Abu-Asab, Richard S. Brush, Martin-Paul Agbaga, S. Patricia Becerra

J Lipid Res. 2023 May; 64(5): 100358. Published online 2023 Mar 17. doi: 10.1016/j.jlr.2023.100358

PMCID:: PMC10233210

Abstract Article PDF–3.4M

Select item 987505216.

Lipolysis-derived linoleic acid drives beige fat progenitor cell proliferation

Ichitaro Abe, Yasuo Oguri, Anthony R.P. Verkerke, Lauar B. Monteiro, Carly M. Knuth, Christopher Auger, Yunping Qiu, Gregory P. Westcott, Saverio Cinti, Kosaku Shinoda, Marc G. Jeschke, Shingo Kajimura

Dev Cell. Author manuscript; available in PMC 2023 Jan 25.

Published in final edited form as: Dev Cell. 2022 Dec 5; 57(23): 2623–2637.e8. doi: 10.1016/j.devcel.2022.11.007

PMCID:: PMC9875052

Abstract Article PDF–3.6M

Select item 987119717.

N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage

Jiesi Xu, Zhenglong Liu, Jianxin Zhang, Siyu Chen, Wei Wang, Xuefan Zhao, Mei Zhen, Xun Huang

Diabetes. 2023 Feb; 72(2): 210–222. Published online 2022 Nov 8. doi: 10.2337/db22-0362

PMCID:: PMC9871197

Abstract Article PDF–67M

Select item 981919718.

Lipid-Laden Lung Mesenchymal Cells Foster Breast Cancer Metastasis via Metabolic Reprogramming of Tumor Cells and Natural Killer Cells

Zheng Gong, Qing Li, Jiayuan Shi, Edison T. Liu, Leonard D. Shultz, Guangwen Ren

Cell Metab. Author manuscript; available in PMC 2023 Dec 6.

Published in final edited form as: Cell Metab. 2022 Dec 6; 34(12): 1960–1976.e9. doi: 10.1016/j.cmet.2022.11.003

PMCID:: PMC9819197

Abstract Article PDF–3.2M

Select item 961883719.

Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency

Jide Oluwadare, Ainara G. Cabodevilla, Ni-Huiping Son, Yunying Hu, Adam E. Mullick, Michael Verano, Jose O. Alemán, Ravichandran Ramasamy, Ira J. Goldberg

J Lipid Res. 2022 Nov; 63(11): 100274. Published online 2022 Sep 15. doi: 10.1016/j.jlr.2022.100274

PMCID:: PMC9618837

Abstract Article PDF–4.7M

Select item 957451520.

A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability

Sebastian H.J. Koochaki, Mikołaj Słabicki, Ryan Lumpkin, Charles Zou, Roger Belizaire, Eric S. Fischer, Benjamin L. Ebert

J Biol Chem. 2022 Oct; 298(10): 102484. Published online 2022 Sep 13. doi: 10.1016/j.jbc.2022.102484

PMCID:: PMC9574515

Abstract Article PDF–1.8M

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