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Select item 114415531.

The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice

Hiroshi Sakai, Hideaki Uno, Harumi Yamakawa, Kaori Tanaka, Aoi Ikedo, Akiyoshi Uezumi, Yasuyuki Ohkawa, Yuuki Imai

Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39): e2407768121. Published online 2024 Sep 18. doi: 10.1073/pnas.2407768121

PMCID:: PMC11441553

Abstract Article PDF–1.1M

Select item 113490292.

Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy

Maria Josè Polanco, Sara Parodi, Diana Piol, Conor Stack, Mathilde Chivet, Andrea Contestabile, Helen C. Miranda, Patricia M.-J. Lievens, Stefano Espinoza, Tobias Jochum, Anna Rocchi, Christopher Grunseich, Raul R. Gainetdinov, Andrew C. B. Cato, Andrew P. Lieberman, Albert R. La Spada, Fabio Sambataro, Kenneth H. Fischbeck, Illana Gozes, Maria Pennuto

Sci Transl Med. Author manuscript; available in PMC 2024 Aug 27.

Published in final edited form as: Sci Transl Med. 2016 Dec 21; 8(370): 370ra181. doi: 10.1126/scitranslmed.aaf9526

PMCID:: PMC11349029

Abstract Article PDF–1.3M

Select item 111516963.

Investigating GABA Neuron–Specific Androgen Receptor Knockout in two Hyperandrogenic Models of PCOS

Irene E Sucquart, Chris Coyle, Valentina Rodriguez Paris, Melanie Prescott, Kelly A Glendining, Kyoko Potapov, Denovan P Begg, Robert B Gilchrist, Kirsty A Walters, Rebecca E Campbell

Endocrinology. 2024 Jul; 165(7): bqae060. Published online 2024 May 24. doi: 10.1210/endocr/bqae060

PMCID:: PMC11151696

Abstract Article

Select item 110964014.

Analysis of androgen receptor expression and activity in the mouse brain

D. Alwyn Dart, Charlotte L. Bevan, Pinar Uysal-Onganer, Wen Guo Jiang

Sci Rep. 2024; 14: 11115. Published online 2024 May 15. doi: 10.1038/s41598-024-61733-9

PMCID:: PMC11096401

Abstract Article PDF–4.3M

Select item 109165015.

A plasma membrane–associated form of the androgen receptor enhances nuclear androgen signaling in osteoblasts and prostate cancer cells

Hema Kalyanaraman, Darren E. Casteel, Shyamsundar Pal China, Shunhui Zhuang, Gerry R. Boss, Renate B. Pilz

Sci Signal. Author manuscript; available in PMC 2024 Mar 6.

Published in final edited form as: Sci Signal. 2024 Jan 30; 17(821): eadi7861. Published online 2024 Jan 30. doi: 10.1126/scisignal.adi7861

PMCID:: PMC10916501

Abstract Article PDF–4.2M

Select item 108730926.

Direct androgen receptor control of sexually dimorphic gene expression in the mammalian kidney

Lingyun Xiong, Jing Liu, Seung Yub Han, Kari Koppitch, Jin-Jin Guo, Megan Rommelfanger, Zhen Miao, Fan Gao, Ingileif B. Hallgrimsdottir, Lior Pachter, Junhyong Kim, Adam L. MacLean, Andrew P. McMahon

Dev Cell. Author manuscript; available in PMC 2024 Nov 6.

Published in final edited form as: Dev Cell. 2023 Nov 6; 58(21): 2338–2358.e5. Published online 2023 Sep 5. doi: 10.1016/j.devcel.2023.08.010

PMCID:: PMC10873092

Abstract Article PDF–1.7M

Select item 108262587.

Interplay between androgen and CXCR4 chemokine signaling in myelin repair

Narimène Asbelaoui, Charly Abi-Ghanem, Géraldine Schlecht-Louf, Hania Oukil, Cindy Degerny, The Netherlands Brain Bank, Michael Schumacher, Abdel Mouman Ghoumari

Acta Neuropathol Commun. 2024; 12: 18. Published online 2024 Jan 30. doi: 10.1186/s40478-024-01730-1

Correction in:: Acta Neuropathol Commun. 2024; 12: 116.

PMCID:: PMC10826258

Abstract Article PDF–12M

Select item 108021838.

Androgen-regulated stromal complement component 7 (C7) suppresses prostate cancer growth

Zhicheng Zhou, Deyong Jia, Ohjoon Kwon, Shan Li, Huiyun Sun, Martine P. Roudier, Daniel W. Lin, Lawrence True, Colm Morrissey, Chad J. Creighton, John K. Lee, Li Xin

Oncogene. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Oncogene. 2023 Aug; 42(32): 2428–2438. Published online 2023 Jul 3. doi: 10.1038/s41388-023-02759-7

PMCID:: PMC10802183

Abstract Article PDF–2.1M

Select item 107625369.

Testosterone reduces hippocampal synaptic damage in an androgen receptor-independent manner

Yizhou Zhang, Meiqin Chen, Huan Chen, Shixiong Mi, Chang Wang, Hongchun Zuo, Leigang Song, Juan Du, Huixian Cui, Sha Li

J Endocrinol. 2024 Feb 1; 260(2): e230114. Prepublished online 2023 Nov 22. Published online 2023 Dec 13. doi: 10.1530/JOE-23-0114

PMCID:: PMC10762536

Abstract Article PDF–11M

Select item 1053857410.

Gene Dosage Changes in KCTD13 Result in Penile and Testicular Anomalies Via Diminished Androgen Receptor Function

Abhishek Seth, Armando Rivera, In-Seon Choi, Olga Medina-Martinez, Shaye Lewis, Marisol O’Neill, Alex Ridgeway, Joshua Moore, Carolina Jorgez, Dolores J. Lamb

FASEB J. Author manuscript; available in PMC 2023 Nov 1.

Published in final edited form as: FASEB J. 2022 Nov; 36(11): e22567. doi: 10.1096/fj.202200558R

PMCID:: PMC10538574

Abstract Article PDF–2.8M

Select item 1040154711.

Androgen receptor coordinates muscle metabolic and contractile functions

Kamar Ghaibour, Mélanie Schuh, Sirine Souali‐Crespo, Céline Chambon, Anouk Charlot, Joe Rizk, Daniela Rovito, Anna‐Isavella Rerra, Qingshuang Cai, Nadia Messaddeq, Joffrey Zoll, Delphine Duteil, Daniel Metzger

J Cachexia Sarcopenia Muscle. 2023 Aug; 14(4): 1707–1720. Published online 2023 May 20. doi: 10.1002/jcsm.13251

PMCID:: PMC10401547

Abstract Article PDF–3.7M

Select item 1035814712.

Androgen Resistance in Female Mice Increases Susceptibility to DMBA-Induced Mammary Tumors

Ulla Simanainen, Yan Ru Gao, Kirsty A. Walters, Geoff Watson, Reena Desai, Mark Jimenez, David J. Handelsman

Horm Cancer. 2012 Jun; 3(3): 113–124. Published online 2012 Feb 28. doi: 10.1007/s12672-012-0107-9

PMCID:: PMC10358147

Abstract Article PDF–703K

Select item 1031239213.

Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic β cells

Weiwei Xu, M.M. Fahd Qadir, Daniela Nasteska, Paula Mota de Sa, Caroline M. Gorvin, Manuel Blandino-Rosano, Charles R. Evans, Thuong Ho, Evgeniy Potapenko, Rajakrishnan Veluthakal, Fiona B. Ashford, Stavroula Bitsi, Jia Fan, Manika Bhondeley, Kejing Song, Venkata N. Sure, Siva S.V.P. Sakamuri, Lina Schiffer, Wandy Beatty, Rachael Wyatt, Daniel E. Frigo, Xiaowen Liu, Prasad V. Katakam, Wiebke Arlt, Jochen Buck, Lonny R. Levin, Tony Hu, Jay Kolls, Charles F. Burant, Alejandra Tomas, Matthew J. Merrins, Debbie C. Thurmond, Ernesto Bernal-Mizrachi, David J. Hodson, Franck Mauvais-Jarvis

Cell Rep. Author manuscript; available in PMC 2023 Jun 30.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112529. Published online 2023 May 17. doi: 10.1016/j.celrep.2023.112529

PMCID:: PMC10312392

Abstract Article PDF–3.8M

Select item 1025364714.

Intratumoral Restoration of miR-137 Plus Cholesterol Favors Homeostasis of the miR-137/Coactivator p160/AR Axis and Negatively Modulates Tumor Progression in Advanced Prostate Cancer

Ruan Pimenta, Carolina Mie Mioshi, Guilherme L. Gonçalves, Patrícia Candido, Juliana A. Camargo, Vanessa R. Guimarães, Caroline Chiovatto, Vitória Ghazarian, Poliana Romão, Karina Serafim da Silva, Gabriel A. dos Santos, Iran A. Silva, Miguel Srougi, William C. Nahas, Kátia R. Leite, Nayara I. Viana, Sabrina T. Reis

Int J Mol Sci. 2023 Jun; 24(11): 9633. Published online 2023 Jun 1. doi: 10.3390/ijms24119633

PMCID:: PMC10253647

Abstract Article PDF–14M

Select item 1024843015.

ZIP9 mediates the effects of DHT on learning, memory and hippocampal synaptic plasticity of male Tfm and APP/PS1 mice

Leigang Song, Huan Chen, Dan Qiao, Bohan Zhang, Fangzhen Guo, Yizhou Zhang, Chang Wang, Sha Li, Huixian Cui

Front Endocrinol (Lausanne) 2023; 14: 1139874. Published online 2023 May 25. doi: 10.3389/fendo.2023.1139874

PMCID:: PMC10248430

Abstract Article PDF–49M

Select item 1023913316.

X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease

Anastasia Gromova, Byeonggu Cha, Erica M. Robinson, Laura M. Strickland, Nhat Nguyen, Mai K. ElMallah, Constanza J. Cortes, Albert R. La Spada

Acta Neuropathol Commun. 2023; 11: 90. Published online 2023 Jun 2. doi: 10.1186/s40478-023-01582-1

PMCID:: PMC10239133

Abstract Article PDF–1.8M

Select item 1022591017.

Deletion of Androgen Receptors From Kisspeptin Neurons Prevents PCOS Features in a Letrozole Mouse Model

Caroline Decourt, Yugo Watanabe, Maggie C Evans, Megan A Inglis, Lorryn C Fisher, Christine L Jasoni, Rebecca E Campbell, Greg M Anderson

Endocrinology. 2023 Jun; 164(6): bqad077. Published online 2023 May 16. doi: 10.1210/endocr/bqad077

PMCID:: PMC10225910

Abstract Article

Select item 1018467418.

Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice

Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A. Youssef, Alain de Bruin, Elvira R. M. Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl

Dis Model Mech. 2023 Jun 1; 16(6): dmm050053. Published online 2023 May 10. doi: 10.1242/dmm.050053

PMCID:: PMC10184674

Abstract Article

Select item 1015467719.

Androgen receptor signaling regulates follicular growth and steroidogenesis in interaction with gonadotropins in the ovary during mini-puberty in mice

Marie M. Devillers, Charlotte M. François, Mélanie Chester, Raphaël Corre, Victoria Cluzet, Frank Giton, Joëlle Cohen-Tannoudji, Céline J. Guigon

Front Endocrinol (Lausanne) 2023; 14: 1130681. Published online 2023 Apr 19. doi: 10.3389/fendo.2023.1130681

PMCID:: PMC10154677

Abstract Article PDF–5.2M

Select item 1012199720.

Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice

Mariarita Galbiati, Marco Meroni, Marina Boido, Matilde Cescon, Paola Rusmini, Valeria Crippa, Riccardo Cristofani, Margherita Piccolella, Veronica Ferrari, Barbara Tedesco, Elena Casarotto, Marta Chierichetti, Marta Cozzi, Francesco Mina, Maria Elena Cicardi, Silvia Pedretti, Nico Mitro, Anna Caretto, Patrizia Risè, Angelo Sala, Andrew P. Lieberman, Paolo Bonaldo, Maria Pennuto, Alessandro Vercelli, Angelo Poletti

Neurotherapeutics. 2023 Mar; 20(2): 524–545. Published online 2023 Jan 30. doi: 10.1007/s13311-023-01343-x

PMCID:: PMC10121997

Abstract Article PDF–7.9M

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