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Select item 100729061.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 92703982.

TRIM24 is an insulin-responsive regulator of P-bodies

Wen Wei, Qiaoli Chen, Minjun Liu, Yang Sheng, Qian OuYang, Weikuan Feng, Xinyu Yang, Longfei Ding, Shu Su, Jingzi Zhang, Lei Fang, Antonio Vidal-Puig, Hong-Yu Wang, Shuai Chen

Nat Commun. 2022; 13: 3972. Published online 2022 Jul 8. doi: 10.1038/s41467-022-31735-0

PMCID:: PMC9270398

Abstract Article PDF–5.2M

Select item 91063033.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 87487894.

Systematic identification of NF90 target RNAs by iCLIP analysis

Valeria Lodde, Matteo Floris, Rachel Munk, Jennifer L. Martindale, Davide Piredda, Catello Mario Panu Napodano, Francesco Cucca, Sergio Uzzau, Kotb Abdelmohsen, Myriam Gorospe, Ji Heon Noh, M. Laura Idda

Sci Rep. 2022; 12: 364. Published online 2022 Jan 10. doi: 10.1038/s41598-021-04101-1

PMCID:: PMC8748789

Abstract Article PDF–4.2M

Select item 81650305.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76994716.

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment

Eun-Jin Choi, Junping Ren, Ke Zhang, Wenzhe Wu, Yong Sun Lee, Inhan Lee, Xiaoyong Bao

Int J Mol Sci. 2020 Nov; 21(22): 8766. Published online 2020 Nov 20. doi: 10.3390/ijms21228766

PMCID:: PMC7699471

Abstract Article PDF–1.7M

Select item 67781377.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 61666828.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 55316119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 417443510.

Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage

Judith Hauptmann, Lukas Kater, Patrick Löffler, Rainer Merkl, Gunter Meister

RNA. 2014 Oct; 20(10): 1532–1538. doi: 10.1261/rna.045203.114

PMCID:: PMC4174435

Abstract Article PDF–239K

Select item 402487811.

TRIM65 regulates microRNA activity by ubiquitination of TNRC6

Shitao Li, Lingyan Wang, Bishi Fu, Michael A. Berman, Alos Diallo, Martin E. Dorf

Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 6970–6975. Published online 2014 Apr 28. doi: 10.1073/pnas.1322545111

PMCID:: PMC4024878

Abstract Article PDF–1.1M

Select item 369055712.

Importance of translation and non-nucleolytic Ago proteins for on-target RNA interference

Ligang Wu, Jihua Fan, Joel G. Belasco

Curr Biol. Author manuscript; available in PMC 2013 Jun 24.

Published in final edited form as: Curr Biol. 2008 Sep 9; 18(17): 1327–1332. doi: 10.1016/j.cub.2008.07.072

PMCID:: PMC3690557

Abstract Article PDF–861K

Select item 360474313.

Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain

Shuo Gu, Lan Jin, Yong Huang, Feijie Zhang, Mark A. Kay

Curr Biol. Author manuscript; available in PMC 2013 Aug 21.

Published in final edited form as: Curr Biol. 2012 Aug 21; 22(16): 1536–1542. Published online 2012 Jul 12. doi: 10.1016/j.cub.2012.06.040

PMCID:: PMC3604743

Abstract Article PDF–3.3M

Select item 341310614.

Argonaute identity defines the length of mature mammalian microRNAs

Prasanna Kumar Juvvuna, Piyush Khandelia, Li Ming Lee, Eugene V. Makeyev

Nucleic Acids Res. 2012 Aug; 40(14): 6808–6820. Published online 2012 Apr 13. doi: 10.1093/nar/gks293

PMCID:: PMC3413106

Abstract Article PDF–8.9M

Select item 333384715.

Expression determinants of mammalian argonaute proteins in mediating gene silencing

Paul N. Valdmanis, Shuo Gu, Nina Schüermann, Praveen Sethupathy, Dirk Grimm, Mark A. Kay

Nucleic Acids Res. 2012 Apr; 40(8): 3704–3713. Published online 2011 Dec 30. doi: 10.1093/nar/gkr1274

PMCID:: PMC3333847

Abstract Article PDF–1.8M

Select item 319082616.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907