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Items: 1 to 20 of 227

1.
METTL3-mediated N6-methyladenosine modification of STAT5A promotes gastric cancer progression by regulating KLF4
Yichen Zang, Zhuangfei Tian, Dandan Wang, Yaxuan Li, Wenhui Zhang, Cunying Ma, Zhenzhi Liao, Wenrong Gao, Lilin Qian, Xia Xu, Jihui Jia, Zhifang Liu
Oncogene. 2024; 43(30): 2338–2354. Published online 2024 Jun 15. doi: 10.1038/s41388-024-03085-2
PMCID:
PMC11271408
AbstractArticlePDF–7.9M
2.
Intracellular Fusobacterium nucleatum infection increases METTL3-mediated m6A methylation to promote the metastasis of esophageal squamous cell carcinoma
Songhe Guo, Fangfang Chen, Linfang Li, Shuheng Dou, Qifan Li, Yuying Huang, Zijun Li, Wanli Liu, Ge Zhang
J Adv Res. 2024 Jul; 61: 165–178. Published online 2023 Aug 22. doi: 10.1016/j.jare.2023.08.014
PMCID:
PMC11258656
AbstractArticlePDF–4.2M
3.
METTL3-mediated NDUFB5 m6A modification promotes cell migration and mitochondrial respiration to promote the wound healing of diabetic foot ulcer
Tao Wang, Xu Li, Yue Tao, Xiaojun Wang, Limeng Li, Jianjun Liu
J Transl Med. 2024; 22: 643. Published online 2024 Jul 9. doi: 10.1186/s12967-024-05463-6
PMCID:
PMC11234709
AbstractArticlePDF–11M
4.
METTL3 regulates thyroid cancer differentiation and chemosensitivity by modulating PAX8
Ning Kang, Zewei Zhao, Zhongyu Wang, Junya Ning, Huijuan Wang, Wei Zhang, Xianhui Ruan, Ming Gao, Xiangqian Zheng
Int J Biol Sci. 2024; 20(9): 3426–3441. Published online 2024 Jun 17. doi: 10.7150/ijbs.84797
PMCID:
PMC11234206
AbstractArticlePDF–10M
5.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
6.
N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension
Kang Kang, Jingjing Xiang, Xingshi Zhang, Yuting Xie, Mengting Zhou, Le Zeng, Junhao Zhuang, Jiahao Kuang, Yuanyuan Lin, Bozhe Hu, Qianmin Xiong, Qing Yin, Qiang Su, Xiaoyun Liao, Jun Wang, Yanqin Niu, Cuilian Liu, Jinglin Tian, Deming Gou
Cell Mol Biol Lett. 2024; 29: 69. Published online 2024 May 13. doi: 10.1186/s11658-024-00590-w
PMCID:
PMC11089701
AbstractArticlePDF–1.5M
7.
METTL3 promotes oxaliplatin resistance of gastric cancer CD133+ stem cells by promoting PARP1 mRNA stability
Huafu Li, Chunming Wang, Linxiang Lan, Leping Yan, Wuguo Li, Ian Evans, E. Josue Ruiz, Qiao Su, Guangying Zhao, Wenhui Wu, Haiyong Zhang, Zhijun Zhou, Zhenran Hu, Wei Chen, Joaquim M. Oliveira, Axel Behrens, Rui L. Reis, Changhua Zhang
Cell Mol Life Sci. 2022 Mar; 79(3): 135. Published online 2022 Feb 18. doi: 10.1007/s00018-022-04129-0
PMCID:
PMC11072755
AbstractArticlePDF–9.6M
8.
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes
Dario F. De Jesus, Zijie Zhang, Natalie K. Brown, Xiaolu Li, Ling Xiao, Jiang Hu, Matthew J. Gaffrey, Garrett Fogarty, Sevim Kahraman, Jiangbo Wei, Giorgio Basile, Tariq M. Rana, Clayton Mathews, Alvin C. Powers, Audrey V. Parent, Mark A. Atkinson, Sirano Dhe-Paganon, Decio L. Eizirik, Wei-Jun Qian, Chuan He, Rohit N. Kulkarni
Nat Cell Biol. Author manuscript; available in PMC 2024 Apr 24.
Published in final edited form as: Nat Cell Biol. 2024 Mar; 26(3): 421–437. Published online 2024 Feb 26. doi: 10.1038/s41556-024-01368-0
PMCID:
PMC11042681
AbstractArticlePDF–8.2M
9.
METTL3 recruiting M2-type immunosuppressed macrophages by targeting m6A-SNAIL-CXCL2 axis to promote colorectal cancer pulmonary metastasis
Peng Ouyang, Kang Li, Wei Xu, Caiyun Chen, Yangdong Shi, Yao Tian, Jin Gong, Zhen Bao
J Exp Clin Cancer Res. 2024; 43: 111. Published online 2024 Apr 11. doi: 10.1186/s13046-024-03035-6
PMCID:
PMC11007974
AbstractArticlePDF–6.8M
10.
Desulfovibrio desulfuricans and its derived metabolites confer resistance to FOLFOX through METTL3
Guifang Li, Huan Liu, Yangmeng Yu, Qian Wang, Chen Yang, Yang Yan, Fang Wang, Yong Mao
eBioMedicine. 2024 Apr; 102: 105041. Published online 2024 Mar 13. doi: 10.1016/j.ebiom.2024.105041
PMCID:
PMC10950750
AbstractArticlePDF–5.0M
11.
METTL3 promotes osteogenic differentiation of human umbilical cord mesenchymal stem cells by up-regulating m6A modification of circCTTN
Shujiang Chen, Xiaoqiong Duan, Yanjin He, Wenchuan Chen
Biosci Rep. 2024 Mar 29; 44(3): BSR20231186. Published online 2024 Mar 12. doi: 10.1042/BSR20231186
PMCID:
PMC10932744
AbstractArticlePDF–1.5M
12.
METTL3 Promotes Osteogenic Differentiation of Human Periodontal Ligament Stem Cells through IGF2BP1-Mediated Regulation of Runx2 Stability
Xuefei Sun, Xiujiao Meng, Yu Piao, Shaojie Dong, Qianqian Dong
Int J Med Sci. 2024; 21(4): 664–673. Published online 2024 Feb 4. doi: 10.7150/ijms.90485
PMCID:
PMC10920842
AbstractArticlePDF–3.5M
13.
METTL3 as a novel diagnosis and treatment biomarker and its association with glycolysis, cuproptosis and ceRNA in oesophageal carcinoma
Xu‐Sheng Liu, Yu Zhang, Zi‐Yue Liu, Yan Gao, Ling‐Ling Yuan, Dao‐Bing Zeng, Fan Tan, Hua‐Bing Wan, Zhi‐Jun Pei
J Cell Mol Med. 2024 Mar; 28(6): e18195. Published online 2024 Mar 1. doi: 10.1111/jcmm.18195
PMCID:
PMC10907846
AbstractArticlePDF–17M
14.
METTL3/YTHDF2 m6A axis mediates the progression of diabetic nephropathy through epigenetically suppressing PINK1 and mitophagy
Fangfang Wang, Juan Bai, Xin Zhang, Dali Wang, Xin Zhang, Jingwen Xue, Haoyang Chen, Shuxiang Wang, Baojin Chi, Jing Li, Xiaoru Ma
J Diabetes Investig. 2024 Mar; 15(3): 288–299. Published online 2023 Nov 28. doi: 10.1111/jdi.14113
PMCID:
PMC10906015
AbstractArticlePDF–3.8M
15.
Silencing of METTL3 prevents the proliferation, migration, epithelial-mesenchymal transition, and renal fibrosis of high glucose-induced HK2 cells by mediating WISP1 in m6A-dependent manner
Yuanzhen Chen, Ping Li, Mei Lin, Ying Jiang, Guiping Tan, Lianfang Huang, Dan Song
Aging (Albany NY) 2024 Jan 31; 16(2): 1237–1248. Published online 2024 Jan 29. doi: 10.18632/aging.205401
PMCID:
PMC10866449
AbstractArticlePDF–1.2M
16.
The RNA m6A writer METTL3 in tumor microenvironment: emerging roles and therapeutic implications
Weiqi Su, Lin Che, Wenting Liao, Huilin Huang
Front Immunol. 2024; 15: 1335774. Published online 2024 Jan 22. doi: 10.3389/fimmu.2024.1335774
PMCID:
PMC10845340
AbstractArticlePDF–1.7M
17.
METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke
Wenjie Su, Xiang Yu, Shan Wang, Xu Wang, Zheng Dai, Yi Li
Cell Biol Toxicol. 2024; 40(1): 8. Published online 2024 Feb 2. doi: 10.1007/s10565-024-09844-x
PMCID:
PMC10834616
AbstractArticlePDF–7.0M
18.
METTL3 facilitates renal cell carcinoma progression by PLOD2 m6A-methylation under prolonged hypoxia
Yimeng Chen, Yichen He, Zhengsheng Li, Nan Zhang, Cuixing Zhou, Xiaozhou He, Dong Xue
Cell Death Dis. 2024 Jan; 15(1): 62. Published online 2024 Jan 17. doi: 10.1038/s41419-023-06411-w
PMCID:
PMC10794171
AbstractArticlePDF–4.5M
19.
FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation
Kai Chen, Yue Wang, Xingna Dai, Jingjing Luo, Shangshang Hu, Zhihui Zhou, Jinglong Shi, Xueshan Pan, Tong Cao, Jun Xia, Yuyun Li, Zhiwei Wang, Jia Ma
Cell Death Dis. 2024 Jan; 15(1): 37. Published online 2024 Jan 12. doi: 10.1038/s41419-024-06425-y
PMCID:
PMC10786907
AbstractArticlePDF–5.1M
20.
Targeting key RNA methylation enzymes to improve the outcome of colorectal cancer chemotherapy (Review)
Chiyun Shao, Yanjie Han, Yuying Huang, Zhe Zhang, Tao Gong, Yajie Zhang, Xiaokang Tian, Mingzhi Fang, Xuan Han, Min Li
Int J Oncol. 2024 Feb; 64(2): 17. Published online 2023 Dec 19. doi: 10.3892/ijo.2023.5605
PMCID:
PMC10783943
AbstractArticlePDF–3.3M

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